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Foo Diddley posted:this guy might have played it: https://crpgaddict.blogspot.com Wow a ton of poo poo came out of uiuc back then
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Oct 28, 2021 01:25
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Ccs posted:The Moderna furry keeps posting this thread every week or so. Has anyone picked apart this study? Seems to contradict the idea that titers need to be continually maxed. Didn’t we already figure out this is an op account by Moderna’s marketing team and not an actual doctor
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Oct 28, 2021 01:25
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mastershakeman posted:Wow a ton of poo poo came out of uiuc back then yeah, the plato system i was kind of surprised to learn that the first RPGs were all multiplayer. i really thought MMOs came after single-player RPGs
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Oct 28, 2021 01:26
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Ccs posted:The Moderna furry keeps posting this thread every week or so. Has anyone picked apart this study? Seems to contradict the idea that titers need to be continually maxed. Seems obviously bullshit, I dunno, maybe it's the two unrelated breakthroughs among the six total employees at my workplace in the past week or the substantial representation of fully vaxxed people in the daily stats for infected and hospitalised. 
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Oct 28, 2021 01:33
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going to see if i can go get a moderna booster around me, or if they'll be sticklers bc i'm in novavax. even with novavax filing for EUA in europe today, my guess is that the heterologous boost is going to be a benefit
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Oct 28, 2021 01:36
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McNugget Buddy posted:https://twitter.com/EricTopol/status/1453489593668366339 by this logic wouldn't taking MDMA / ecstasy be a good idea early in infection? IIRC it basically wipes out all your serotonin after the trip (and why people crash hard after a night of intense euphoria)
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Oct 28, 2021 01:43
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McNugget Buddy posted:https://twitter.com/EricTopol/status/1453489593668366339 Hoo boy. Now that's something to be really concerned about. Imagine normal people just overdosing themselves daily on SSRI nationally wide
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Oct 28, 2021 01:43
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Foo Diddley posted:this guy might have played it: https://crpgaddict.blogspot.com Tks! I'm interested to see if it's on there!
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Oct 28, 2021 01:44
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Buddy, I have so little serotonin it's a problem. Don't have much dopamine bouncing around there either. Gotta lick elevator buttons at the hospital just to feel alive
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Oct 28, 2021 01:46
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facetoucher cat posted:Buddy, I have so little serotonin it's a problem. Don't have much dopamine bouncing around there either. Gotta lick elevator buttons at the hospital just to feel alive lol would make a great sci fi plot that a virus wipes out everyone on the planet except clinically depressed people who are chronically low on serotonin. the survivors have to begrudgingly repopulate the world, which they hate.
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Oct 28, 2021 01:47
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mod sassinator posted:lol would make a great sci fi plot that a virus wipes out everyone on the planet except clinically depressed people who are chronically low on serotonin. the survivors have to begrudgingly repopulate the world, which they hate. Also their libido is shot and they have to do it for hours.
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Oct 28, 2021 01:53
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the bleak shall inherit the earth
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Oct 28, 2021 01:58
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mod sassinator posted:lol would make a great sci fi plot that a virus wipes out everyone on the planet except clinically depressed people who are chronically low on serotonin. the survivors have to begrudgingly repopulate the world, which they hate. mod sassinator posted:the bleak shall inherit the earth my entire life has prepared me for this moment
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Oct 28, 2021 02:04
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Pepe Silvia Browne posted:the schwarma joke is superfluous, it makes the hibachi kind of a hat on a hat  but it did make me want to get a schwarma so i guess it succeeded there?
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Oct 28, 2021 02:08
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mod sassinator posted:the bleak shall inherit the earth I like this
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Oct 28, 2021 02:10
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https://twitter.com/renzpolster/status/1453299718432374784?s=21 lol lmao
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Oct 28, 2021 02:12
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mod sassinator posted:yeah i don't think we have a new delta or other variant growing. it's that kids went back to schools, cases grew, people noticed growing cases and went woahhhh there dial it back... and now a couple weeks later people think it's over and are going back out to eat and take risks again. weather has been crap for over a week too and i noticed restaurants were packed saturday night while walking around I do wonder how much child vaccines might help blunt the winter surge, if at all. Some studies have shown school age kids are a big cause of asymptomatic spread, and then eventually symptomatic household spread. Curious what areas with high child vaccine uptake + universal masking will look like this winter. My son's private high school in Connecticut mandated mRNA vaccines for every student and universal masking. A large majority of kids are boarding students and so far they haven't had any cases. We're homeschooling my youngest until she can be vaccinated at minimum. I don't know what the hell is going on in Connecticut. Mask compliance sucks, all of my neighbors are acting like COVID is over with kids running around unmasked playing together, hundreds of kids are unmasking at lunch in school, 70 kids to a school bus, doing 'modified' quarantines in schools, etc but CT's rates have been some of the lowest in the country. It doesn't make sense.
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Oct 28, 2021 02:15
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ugh unless it changes the school mask mandate will go away in my kids school district 60 days after 5-11 can get shots. makes no sense
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Oct 28, 2021 02:19
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sonatinas posted:ugh unless it changes the school mask mandate will go away in my kids school district 60 days after 5-11 can get shots. makes no sense so they'll stop making school kids wear masks once the school kids can get vaccinated? that does make sense, doesn't it? what am i missing 
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Oct 28, 2021 02:21
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So I'm a bit confused about this. Like I thought the current understanding of what causes Long COVID is the fact the virus is able to cause significant organ damage or clotting before the body is able to defeat the infection. If that was truly the cause of Long COVID, then wouldn't it logically follow as necessary that vaccinated individuals - at least those recently vaccinated with big titers - should have much lower rates of Long COVID since their big heaving titers are able to beat back the infection before it's able to cause said damage? Like I thought the same mechanisms that make it effective at preventing hospitalization and death would logically also make it effective ad preventing Long COVID. Still not to the point where any sane person would want to risk it, but yeah, still also to the point where you'd expect to see a statistical difference in studies like this.
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Oct 28, 2021 02:27
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RoboChrist 9000 posted:So I'm a bit confused about this. Like I thought the current understanding of what causes Long COVID is the fact the virus is able to cause significant organ damage or clotting before the body is able to defeat the infection. If that was truly the cause of Long COVID, then wouldn't it logically follow as necessary that vaccinated individuals - at least those recently vaccinated with big titers - should have much lower rates of Long COVID since their big heaving titers are able to beat back the infection before it's able to cause said damage? Like I thought the same mechanisms that make it effective at preventing hospitalization and death would logically also make it effective ad preventing Long COVID. Still not to the point where any sane person would want to risk it, but yeah, still also to the point where you'd expect to see a statistical difference in studies like this. If your titers fought it off you never would've been a case
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Oct 28, 2021 02:30
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RoboChrist 9000 posted:So I'm a bit confused about this. Like I thought the current understanding of what causes Long COVID is the fact the virus is able to cause significant organ damage or clotting before the body is able to defeat the infection. If that was truly the cause of Long COVID, then wouldn't it logically follow as necessary that vaccinated individuals - at least those recently vaccinated with big titers - should have much lower rates of Long COVID since their big heaving titers are able to beat back the infection before it's able to cause said damage? Like I thought the same mechanisms that make it effective at preventing hospitalization and death would logically also make it effective ad preventing Long COVID. Still not to the point where any sane person would want to risk it, but yeah, still also to the point where you'd expect to see a statistical difference in studies like this. These are breakthrough infections. So it doesnt compare the relative rates of vaxed vs not. Thie paper is once infected vaxed and unvaxed does vaxed do better and the answer is sorta. Yes vax people are going to be infected less but keep in mind we know that if antibodies wane you have very little protection against infection over someone who is unvaxed. This shows how even mild infection can be dangerous to those infected.
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Oct 28, 2021 02:35
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RoboChrist 9000 posted:So I'm a bit confused about this. Like I thought the current understanding of what causes Long COVID is the fact the virus is able to cause significant organ damage or clotting before the body is able to defeat the infection. If that was truly the cause of Long COVID, then wouldn't it logically follow as necessary that vaccinated individuals - at least those recently vaccinated with big titers - should have much lower rates of Long COVID since their big heaving titers are able to beat back the infection before it's able to cause said damage? Like I thought the same mechanisms that make it effective at preventing hospitalization and death would logically also make it effective ad preventing Long COVID. Still not to the point where any sane person would want to risk it, but yeah, still also to the point where you'd expect to see a statistical difference in studies like this.
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Oct 28, 2021 02:37
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McNugget Buddy posted:Didn’t we already figure out this is an op account by Moderna’s marketing team and not an actual doctor I'm pretty sure Chise is a real person. They're guest of honor at an upcoming furry con.
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Oct 28, 2021 02:43
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RoboChrist 9000 posted:So I'm a bit confused about this. Like I thought the current understanding of what causes Long COVID is the fact the virus is able to cause significant organ damage or clotting before the body is able to defeat the infection. If that was truly the cause of Long COVID, then wouldn't it logically follow as necessary that vaccinated individuals - at least those recently vaccinated with big titers - should have much lower rates of Long COVID since their big heaving titers are able to beat back the infection before it's able to cause said damage? Like I thought the same mechanisms that make it effective at preventing hospitalization and death would logically also make it effective ad preventing Long COVID. Still not to the point where any sane person would want to risk it, but yeah, still also to the point where you'd expect to see a statistical difference in studies like this. If you click through to the PDF, their data shows vaccines protected against respiratory failure, hypercoagulopathy and death at higher rates than in the unvaccinated: https://www.medrxiv.org/content/10.1101/2021.10.26.21265508v1.full.pdf+html
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Oct 28, 2021 02:44
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Foo Diddley posted:so they'll stop making school kids wear masks once the school kids can get vaccinated? that does make sense, doesn't it? what am i missing looking at the data of cohorts already vaxed, 5-11 will be the lowest percentage of eligible groups since the trend is downward, so regardless of percentage of kids not vaxed they will drop the mandate ,it’s a repeat of what happened earlier this year with everyone else
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Oct 28, 2021 02:44
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long covid could be be autoimmune. Development of ACE2 autoantibodies after SARS-CoV-2 infection https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0257016 "Conclusions Many patients with a history of SARS-CoV-2 infection have antibodies specific for ACE2. Patients with ACE2 antibodies have lower activity of soluble ACE2 in plasma. Plasma from these patients also inhibits exogenous ACE2 activity. These findings are consistent with the hypothesis that ACE2 antibodies develop after SARS-CoV-2 infection and decrease ACE2 activity. This could lead to an increase in the abundance of Ang II, which causes a proinflammatory state that triggers symptoms of Post-Acute Sequelae of SARS-CoV-2 infection (PASC)."
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Oct 28, 2021 02:45
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Foo Diddley posted:so they'll stop making school kids wear masks once the school kids can get vaccinated? that does make sense, doesn't it? what am i missing you’re trading all kids wearing masks for some kids being vaccinated i don’t know the math on how much protection mask mandates buy you but i bet it’s more than a partially vaccinated population
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Oct 28, 2021 02:45
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mod sassinator posted:. it's that kids went back to schools, cases grew, people noticed growing cases and went woahhhh there dial it back... schools have been remarkably tame for spread. out here there have been 70 cases total (of which 9 are in school spread) in the district for 8000+ kids and staff in two months. basically a quarter of a percent of the in school population catches it a week, somewhere else. I had thought delta and different NPIs was going to make that worse. but it’s remarkably similar to last year and og covid.
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Oct 28, 2021 02:45
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mod sassinator posted:the bleak shall inherit the earth
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Oct 28, 2021 02:46
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sonatinas posted:looking at the data of cohorts already vaxed, 5-11 will be the lowest percentage of eligible groups since the trend is downward, so regardless of percentage of kids not vaxed they will drop the mandate ,it’s a repeat of what happened earlier this year with everyone else Dren posted:you’re trading all kids wearing masks for some kids being vaccinated ahhh yeah, okay. stupid me, i thought it meant all the kids would be vaccinated
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Oct 28, 2021 02:48
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Rauros posted:long covid could be be autoimmune. Yeah I thought this article explains it pretty clearly. https://www.dicardiology.com/content/covid-long-hauler-symptoms-may-be-caused-antibody-attacks-ace2 Hope they’re already working on the drugs to treat it. I’m almost completely recovered from my breakthrough infection but don’t want to wake up in a month with long covid...
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Oct 28, 2021 03:01
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mdemone posted:Great news! My school has not had a single county-reported case of Covid since opening in September! Of course, around 20% of my students have missed more than a week of class already, and two teachers have been hospitalized. The official Vic government case alerts site now has a warning label saying "Not all exposure sites are published online" which is a bit of an understatement since they're only showing 4 covid exposure sites over the last 14 days for the entirety of the Greater Melbourne area, even though we're getting about 2000 new infections reported every day: 
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Oct 28, 2021 03:02
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Spoondick posted:covid with pneumonia coinfection seem common since pneumonia is an opportunistic bacteria, I could only see it helping, and the eligibility criteria for pneumonia vaccines was recently expanded to include younger people with risk factors Yeah, purely anecdotal data: my boyfriend has/had covid that immediately transitioned into bacterial pneumonia, and it’s worth noting that he’s never had the pneumonia vax. I had the pneumonia vax series a couple of years ago and did not get post-covid pneumonia. Obviously there are lots of other variables at play, but I’m guessing getting the pneumonia vax can only help.
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Oct 28, 2021 03:04
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Bar Ran Dun posted:schools have been remarkably tame for spread. out here there have been 70 cases total (of which 9 are in school spread) in the district for 8000+ kids and staff in two months. basically a quarter of a percent of the in school population catches it a week, somewhere else. I had thought delta and different NPIs was going to make that worse. but it’s remarkably similar to last year and og covid. At least for our district, we're having lower spread this fall than last spring. Super vaccinated area that got vaxxed pretty late I think so that's probably the big difference; less parents having it We're even testing all kids this fall and weren't in the spring
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Oct 28, 2021 03:06
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mod sassinator posted:the bleak shall inherit the earth omg stop doomposting  i literally cannot take a joke and will take this seriously
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Oct 28, 2021 03:10
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Lastgirl posted:omg stop doomposting right?????a??
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Oct 28, 2021 03:14
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silicone thrills posted:Light rail safety Goddamn secureclicks are huge
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Oct 28, 2021 03:25
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I’m really loving bitter that my choices right now are to continue taking taltz and go out as little as possible while getting boosted every six months because millions of people would rather see me dead than wear a loving mask or stop taking taltz and have everyone treat me like a leper because I look like the polka dot man.
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Oct 28, 2021 03:27
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