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OK baizuo posted:I honestly haven't been able to keep up with the thread this week. What's the real deal as far as being reinfected with BA.2 after a previous omicron infection? I asked earlier today and it seems to be the sort of thing where it’s too soon to officially say but reinfections are definitely happening weeks after recovering from omicron and it sure seems like it’s BA.1 infections rolling right into BA.2 infections but not enough solid data exists yet to say that, could be BA.1 into BA.1 or idk Delta? So maybe just behave as if you can get immediately reinfected for safety’s sake.
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Jan 28, 2022 08:32
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Wild Type vaccines are slightly more effective against BA.2 than they were against BA.1 https://twitter.com/kallmemeg/status/1486821549458001927 
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Jan 28, 2022 08:34
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BA.2 has some kind of a fitness advantage, and I think it has to have significant evasion of antibodies generated by BA.1 infection. Its growth rate cannot be plausibly be due to a higher basic reproductive number and/or shorter generation time. It has to be reinfecting.
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Jan 28, 2022 08:34
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The rich are continuing to deny the essentials of life to the poor. We're lucky in the first world that the best covid vaccines are easily available, while companies gave scraps to South Africa and India. Bill Gates lobbied hard to stop the Global South from getting mRNA vaccines, and has the blood of millions on his hands. Pfizer's slow response to Omicron is exactly what you'd expect if they want to keep letting covid kill old and disabled people forever. And the billionaire class that murdered 20 million people over the last two years has controlled the media so effectively that the debate is "Should we get rid of all covid precautions?" vs "should we get rid of all covid precautions and vaccinate people?" The only sane answer is to eliminate the virus through vaccines, high-quality masks, and paying people to stay home, but the billionaires would rather let us die.
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Jan 28, 2022 08:35
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https://twitter.com/DrSalandyinGA/status/1486126028200333319
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Jan 28, 2022 08:35
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McNugget Buddy posted:Wild Type vaccines are slightly more effective against BA.2 than they were against BA.1 Bedford and others predicted this from the structure some time ago, and it’s nice to see that confirmed. BA.2 isn’t great, but as far as variants capable of causing a surge right after‐BA.1 go, this is arguably the least bad thing we could have seen.
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Jan 28, 2022 08:38
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Pittsburgh Fentanyl Cloud posted:lol I didn't know about Microcovid. I plugged in my 20 minute biweekly grocery run in an N95 and it's very high risk. hell yeah McCracAttack posted:
nice very nice thank you number
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Jan 28, 2022 08:38
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"all the rats were dead after being reinfected 11 times"
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Jan 28, 2022 08:38
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Chamale posted:I called them, they're out of stock. If anyone finds a place that does have Auras in stock, please let me know. https://www.grainger.com/product/3M-Disposable-Respirator-21LP02 Backordered, expected to arrive between Tue. Feb 08 - Tue. Feb 22. and also a bit pricier than normal but so what
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Jan 28, 2022 08:41
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jetz0r posted:Most sites are showing a 2 week lead time on auras right now, now that I'm looking closer. lmao
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Jan 28, 2022 08:42
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platzapS posted:this seems like ages ago WAP was released before the vaccines
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Jan 28, 2022 08:43
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rshughes knows whats up  
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Jan 28, 2022 08:44
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McNugget Buddy posted:Wild Type vaccines are slightly more effective against BA.2 than they were against BA.1 im the negative 26% VE vs. BA.2 on the rear end end of the 95% CI lol
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Jan 28, 2022 08:45
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Mild VEI
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Jan 28, 2022 08:47
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Tzen posted:rshughes knows whats up 
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Jan 28, 2022 08:49
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Morbus posted:im the negative 26% VE vs. BA.2 on the rear end end of the 95% CI lol Haha gently caress good catch, double checked the linked doc and it's not a typo. Knowing the demographics of the population sample that made up the negative range would be.. very valuable to say the least..
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Jan 28, 2022 08:54
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 "It's a living!"
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Jan 28, 2022 08:56
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Tzen posted:rshughes knows whats up RSHughes hosed up my order but they eventually made it right and were very nice on the phone for a small fry customer such as myself Glad i bought auras from them when they were 97 cents 
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Jan 28, 2022 08:57
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Isizzlehorn posted:Haha gently caress good catch, double checked the linked doc and it's not a typo. I mean, when a vaccine has low efficacy, it's inevitable that, for purely statistical reasons, your confidence interval will dip into the negatives. Like, if your actual VE is exactly zero, your CI ought to extend equally into the negative and positive. Since the mean VE for BA.2 in the 25+ wk cohort is notably lovely, it makes sense that if your CI is that broad (66 pt span lol), a lot of it will be in the negatives. So I don't think it should be taken as evidence for ADE or anything spicy like that. Still funny though, lol
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Jan 28, 2022 09:03
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lolStrep Vote posted:Also rename mastershakesman to shittytakesman
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Jan 28, 2022 09:03
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OK baizuo posted:RSHughes hosed up my order but they eventually made it right and were very nice on the phone for a small fry customer such as myself i see they're still offering the blue strapped auras for $1, not bad
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Jan 28, 2022 09:03
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Pittsburgh Fentanyl Cloud posted:
Haha don't feel bad PFC. I remember the goon who posted here with their filters on at completely mismatched angles. It takes some time to get used to it; imagine if the pandemic had been running for two years or something. Then maybe you could advocate for everyone to wear respirators since they would have plenty of time to learn how.
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Jan 28, 2022 09:04
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Isizzlehorn posted:Knowing the demographics of the population sample that made up the negative range would be.. very valuable to say the least.. The negative figures have popped up for double-vaxxed in multiple studies I remember after the first one came out, it was handwaved away as an anomaly because "people with only 2 doses must be behaving differently" or whatever If it's not ADE then...what the hell is making them more susceptible to infection?
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Jan 28, 2022 09:05
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Aww, Australia only hit 98 deaths. The first three figure death day will have to wait. (until tomorrow probably)
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Jan 28, 2022 09:05
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McNugget Buddy posted:"all the rats were dead after being reinfected 11 times" Lol I remember that. We have some wild years ahead of us. I despair for the future of our children
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Jan 28, 2022 09:06
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Platystemon posted:Bedford and others predicted this from the structure some time ago, and it’s nice to see that confirmed. We still don't even know how bad BA.1 is yet. The wave has not washed over us. We have not felt the aftershocks. We have no idea what Omicron has in store for us.
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Jan 28, 2022 09:07
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You know... it's been three years of the pandemic, and still no one recognizes the mexican movie about a pandemic that pretty much predicted it all https://www.youtube.com/watch?v=wzWKoYZltbE "It's a new form of immortality, since they are not officcialy dead" "We're just the Fourth Power. If those above us are in accordance, there's little we can do. A News like this is so big it gets out of our hands" Or just ignore it because it's not english language. Do as you will. Just wanted to post it. Thought some of you would appreciate it.
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Jan 28, 2022 09:08
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UnfortunateSexFart posted:Aww, Australia only hit 98 deaths. can we not
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Jan 28, 2022 09:10
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Blackhawk posted:You know I've worked using and handling dangerous chemicals that produce either toxic gasses/aerosols or flammable gasses and explosive atmospheres. When working in these conditions there's no question about the level of PPE required for employees by law, in most cases a full face respirator would be a minimum, but in a few cases where I used to work we also had PAPR hoods with belt-mounted filters and supplied air respirators from hoses and a central air supply. Morbus posted:Actually these standards were widely and routinely followed for viral hazards in workplaces until SARS-CoV-2, lmao Blackhawk posted:https://www.cdc.gov/sars/guidance/f-lab/app5.html Blackhawk posted:Like imagine you're somebody working in a viral research lab. BSL-3, so the same kind of safety protocols as TB, SARS-1, MERS, yellow fever, west nile etc. You're holding a small plastic vial containing a gram of cell material with a SARS-CoV-2 infection. You're wearing a PAPR hood and gloves, and you're handling the vial inside a biological safety cabinet with powerful extraction fans and HEPA filters. This is a picture of you doing your work:  at all of this after having spent 5 hours in a crowded office setting where most folks were maskless because they were at their desk or drinking coffee or whatever dumb loving rules lawyering they were doingbased secure click save me
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Jan 28, 2022 09:10
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The Oldest Man posted:Looks like cope's back on the menu boys 
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Jan 28, 2022 09:17
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Steve Yun posted:
Krispy Kreme has done more to promote public health than the CDC lmao
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Jan 28, 2022 09:20
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McNugget Buddy posted:"all the rats were dead after being reinfected 11 times" So I'm not 100% sure about which particular study this factoid is referencing. But I'm pretty sure it's this one: https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC2787736/  They serially passaged SARS-CoV1 through mice for which the virus is not lethal. This produced mouse-adapted strains that were increasingly virulent. Eventually, a highly lethal strain was produced that killed all the mice who were infected with an inoculum size that produced zero deaths in the original strain. So the result wasn't that "serial reinfection with the same relatively non-lethal SARS-CoV eventually kills all the mice", it was that "if you keep loving around, you may eventually produce a very lethal strain" idk maybe I'm wrong, but I think the whole "all the mice dead after X infections" is a misinterpretation / gradual distortion of this paper.
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Jan 28, 2022 09:20
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The Oldest Man posted:Looks like cope's back on the menu boys People sure get paid to have opinions, huh
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Jan 28, 2022 09:20
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*28 variants later* HYPERimmunity is now the word to embrace
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Jan 28, 2022 09:21
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Morbus posted:So I'm not 100% sure about which particular study this factoid is referencing. But I'm pretty sure it's this one: Are you sure that the virus didn't instead mutate to become MILD and the mice stopped dying at all? That seems more likely
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Jan 28, 2022 09:22
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Trixie Hardcore posted:That lil rona looks like it’s flipping double birds I wouldn't mind this for $75 an hour tbh. Beats being an EMT because at least if they're already dead I can't gently caress things up any worse
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Jan 28, 2022 09:22
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Steve Yun posted:
This is not showing a lot of respect for my blood sugar but sure I'll consider lying to a nurse about being gay to get a big box of donuts.
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Jan 28, 2022 09:23
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Cup Runneth Over posted:Are you sure that the virus didn't instead mutate to become MILD and the mice stopped dying at all? That seems more likely You're right. Clearly the problem is that the mice were unvaxxed
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Jan 28, 2022 09:27
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Super Immunity II Turbo HD Remix
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Jan 28, 2022 09:29
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Hashy posted:This one is actually sending me insane. Health messaging has decoupled from reality. I need someone to explain what he might be talking about when he says "herd immunity is not synonymous with stopping the disease from spreading" before my skull opens up and shoots my brain matter into the air from the pressure of it all yes can we please stop causing each other psychic damage by posting every goddamn gibberish brained Twitter take. having to parse what the fuuuuuuck anyone is saying and then. grade it on a scale of how insane it is is horribly exhausting.
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