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Albino Squirrel posted:The two primary IV ones that have been bandied about are hydromorphone and diacetylmorphine (heroin). For reasons of palatability hydromorphone was chosen, because 'literal heroin' is a tough sell to people who aren't familiar with the opioid world. Also, IV hydro is pretty widely available in the medical world because it's literally used all the time for non-addiction reasons; when they knocked my fat rear end out for a knee arthroscopy, part of the cocktail they used was hydromorphone. So part of the choice was familiarity. Also, hydromorphone is one of the cleaner opioids in terms of metabolites especially in renal failure, so there's fewer side effects. Just to be clear, I was simply blown away by the tolerances of some of your patients. No criticism, judgement, or moralizing intended. "armchair medicine" is always weak stuff, I'm sure that you & other medical professionals are dosing & prescribing appropriately. Suboxone is great stuff but the withdrawals were absolute hell on earth. I wasn't able to sleep a wink until day 5, and that's just the most memorable symptom. Thanks for the thorough explanation
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Mar 1, 2022 01:01
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The Lone Badger posted:My medical knowledge is extremely limited, but would it be possible to have a slow release implant like they use for birth control or an implanted pump like they use for insulin, keeping a constant concentration of (appropriate drug) in the bloodstream to prevent craving while being very difficult to misuse / increase the concentration? You've just described Sublocade; a once-monthly subcutaneous injection that releases buprenorphine at a controlled rate. https://www.sublocade.com/?utm_camp...wE&gclsrc=aw.ds King Possum III fucked around with this message at 06:31 on Mar 1, 2022 |
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Mar 1, 2022 06:28
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Kevin Sabet had better watch out ‘cause there’s a new shitlord in town: https://twitter.com/zachwritesstuff/status/1525847402334367744?s=21&t=6RuVPr8oCZL5bcrOhAK9cA
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May 15, 2022 16:30
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gently caress an Opioid Epidemic bring in the Oedipal Epidemic
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May 16, 2022 22:19
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So interesting development here in Canada on our similar Opioid issue: https://twitter.com/AndreaWoo/status/1531699777238208512?s=20&t=DVjQDYh0G9SMYYNU0Nh29g Feds announced starting next year (and in BC only for now), small amounts of hard drugs are going to be decriminalized. Up to 2.5 grams, with exceptions for schools and airports etc... No charges, no ticket, no seizures if under that amount. Amount is smaller than BC was asking for (they wanted 4.5g) but it's a start I suppose.
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May 31, 2022 20:52
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hey, good. Where I live in NY all the older folks (esp. the older Italian-Americans) are losing their minds about weed.
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May 31, 2022 21:49
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I'm surprised at no seizures, that's like a hundred bags of fentanyl. Am I correctly understanding that the harm reduction is in trying to destigmatize addiction and recognizing that jail isn't going to help these folks?
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Jun 1, 2022 19:46
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n/m
King Possum III fucked around with this message at 02:41 on Jun 2, 2022 |
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Jun 2, 2022 02:39
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https://www.nytimes.com/2022/09/29/opinion/opiate-fentanyl-epidemic.html Covers a lot of territory with not a lot of paint but gist is I think through just through dint of social channels that have been qualitatively similar since caveman times (even if many transmission media are new) opioids look to be in a self-limiting phase, in the US at least. A coherent, moral policy response would have been nice, though!
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Sep 29, 2022 15:48
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