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cowofwar posted:Gene therapy fixes mutations and that's not what drives the aging process. I think the idea is you turn off the limit on cell reproduction. Right now your cells will only reproduce a certain number of times. So even if you eliminate everything that makes you shake or tremble and are fantastically lucky crossing roads, your genetically perfect body will still suffer a catastrophic failure at around your 124th birthday. I'm not sure how you handle cardiovascular disease. Even super healthy elderly adults have hardened arteries.
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Apr 22, 2016 19:13
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Krispy Kareem posted:I think the idea is you turn off the limit on cell reproduction. Right now your cells will only reproduce a certain number of times. So even if you eliminate everything that makes you shake or tremble and are fantastically lucky crossing roads, your genetically perfect body will still suffer a catastrophic failure at around your 124th birthday. Gene therapy will be and has been used to fix somatic point mutations that cause disease.
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Apr 22, 2016 19:19
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Just become a lich for the low price of 100k gold pieces and a phylactery
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Apr 22, 2016 19:48
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Parallel Paraplegic posted:But they'll be young forever at least because they'll be able to reverse the aging process because gene therapy is magic and all the actual physical changes to your body goes through in aging is just something that can be reversed, like you just reset your body's odometer and suddenly your bones are strong and your organs are new and loving with the stuff that controls cell growth is definitely not going to cause all sorts of fascinating new kinds of cancer 10 years later There are a number of people seriously researching what it would take to completely cure old age. Genetic manipulation will certainly be part of it, but staying forever young will probably entail a pretty long list of treatments to fix all the things that wear out (especially if you're already old when this stuff becomes available).
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Apr 22, 2016 19:56
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cowofwar posted:Yeah but current gene therapy focuses on CRISPR/Cas9 technology which can't do anything about telomere shortening (which limits stem cell division to a finite number). You could hypothetically use CRISPR to flip the switch on telomerase promoters to keep those chromosme butts fit af. However, the real problem with gene therapy that nobody talks about is that it is basically a prescription for cancer. You have 37 trillion cells, and need to change one base pair in each one. Even with a one in a billion error rate, you are going to accrue many many wrong mutations, some of which may cause cancer. Even if it only causes cancer in 1 out of 100 people, that's a pretty big risk. After all, it only takes one cancerous cell to cause disease. In vivo gene therapy is still many decades away, in vitro gene therapy though, is right around the corner. Sepherothic fucked around with this message at 20:57 on Apr 22, 2016 |
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Apr 22, 2016 20:11
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Sounds expensive. Dying: GWM
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Apr 22, 2016 20:48
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Forever young isn't hard. Just have one of two parents be Asian, duh. Edit: Oh yeah, and sunscreen. It's GWM. Cheaper than both chemo and prostitutes. Blinkman987 fucked around with this message at 22:19 on Apr 22, 2016 |
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Apr 22, 2016 21:55
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cowofwar posted:Yeah but current gene therapy focuses on CRISPR/Cas9 technology which can't do anything about telomere shortening (which limits stem cell division to a finite number). http://bioviva-science.com/2016/04/21/first-gene-therapy-successful-against-human-aging/ quote:if early data is accurate, it is already the world’s first successful example of telomere lengthening via gene therapy in a human individual
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Apr 22, 2016 22:09
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Just what social security needs, a bunch of immortals
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Apr 22, 2016 22:16
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Barry posted:Just what social security needs, a bunch of immortals That's very true. In the end there can only be one.
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Apr 22, 2016 22:18
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Barry posted:Just what social security needs, a bunch of immortals At least they'd be able to wipe their own asses. With people having fewer kids, numerous countries are in very real danger of having more old people than they can care for. There really aren't a lot of options beyond "make it possible for people to live active, independent lives until they get bored of existing" or "go all Logan's Run".
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Apr 23, 2016 01:05
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Cockmaster posted:At least they'd be able to wipe their own asses. With people having fewer kids, numerous countries are in very real danger of having more old people than they can care for. There really aren't a lot of options beyond "make it possible for people to live active, independent lives until they get bored of existing" or "go all Logan's Run". There's also "accept young immigrants into your society" but half of pretty much every country will take to the streets and riot if you suggest it.
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Apr 23, 2016 01:14
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Inverse Icarus posted:There's also "accept young immigrants into your society" but half of pretty much every country will take to the streets and riot if you suggest it. Plus it raises the question of who's going to take tare of the old people in their home countries.
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Apr 23, 2016 03:06
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Cockmaster posted:Plus it raises the question of who's going to take tare of the old people in their home countries. The immigrants tend to come from developing countries where there are higher numbers of children anyway. Solve easy/casual space flight and terraforming planets before we get around to functional immortality, I say!
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Apr 23, 2016 03:12
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I haven't thrown a house party on forever, nor have I smoked a brisket in forever. I essentially bought a bunch of meat and cheap-to-middling beer to give away to my friends tomorrow instead of  ing my money.Also, my roommate is moving out in a week and I'm in no hurry to replace that income stream because I'm worried that the older I get, the less likely I'll have a roommate that works out well (although he may have been the best I've ever had regarding money in vs. wear and tear or cramping my lifestyle in any way). I want more money, but I want it to be worth the hassle.
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Apr 23, 2016 04:18
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I just watched the big short. Saving money is bwm
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Apr 23, 2016 06:23
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HoogieChooChoo posted:I just watched the big short. Saving money is bwm I told one of my friends at the bar last night to watch it. I told him that JP Morgan has 63% of its option positions in OTC options. The same ones that were cashed in during the previous crisis. The banks have learnt nothing.
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Apr 23, 2016 07:55
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Devian666 posted:I told one of my friends at the bar last night to watch it. I told him that JP Morgan has 63% of its option positions in OTC options. The same ones that were cashed in during the previous crisis. The banks have learnt nothing.
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Apr 23, 2016 08:05
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It's not like Icarus didn't successfully fly around for a while before running into issues 🐒.
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Apr 23, 2016 19:34
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My employer is a big investor in Theranos.
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Apr 23, 2016 20:19
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Krispy Kareem posted:My employer is a big investor in Theranos. http://www.bloomberg.com/news/articles/2016-04-18/theranos-is-under-investigation-by-sec-u-s-attorney-s-office Investing in a disruptive unicorn startup headed by a Stanford dropout: BWM.
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Apr 23, 2016 20:52
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Krispy Kareem posted:My employer is a big investor in Theranos. Working at Walgreens: BWM
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Apr 23, 2016 22:01
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SiGmA_X posted:My company has a bunch (not that many, few hundred million notional, single digit millions FV) of OTC options with JPM. We won nicely Q1-3 last year, and JPM (and other banks) has won for the last 2Q.. That's the sort of performance you'd expect under usual conditions. I hope your company is up on them with 3 good quarters.
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Apr 23, 2016 23:24
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Just got back from seeing a friend of mine. Said he's got about $45,000 in cryptocurrency, on a $2200 investment. Asked him why he didn't just cash out now. "I can only cash out $10k per day" Ok that's only 5 days to get out "With these kinds of gains it could be worth a millions by the end of the year!" Ok, why not cash out your original investment plus some? "Because it's going to keep gaining, I don't want to lose those future gains!" Ugh. What the gently caress is Ethereum anyway? edit: the good news is I explained margin trading to him, and I think he understood it and said he'll avoid doing that. I don't even know how you can trade cryptocurrency on margin.
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Apr 23, 2016 23:45
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You can trade anything on margin.
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Apr 23, 2016 23:52
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The Mandingo posted:Just got back from seeing a friend of mine. Said he's got about $45,000 in cryptocurrency, on a $2200 investment. Asked him why he didn't just cash out now. You should crosspost this to the bitcoin thread in YOSPOS.
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Apr 24, 2016 03:34
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https://www.storehouse.co/stories/o9lon-concrete-cowboys i hope these young men don't end up horsepoor
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Apr 24, 2016 03:56
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Which scam was this? I got a knock on my door the other day. It was my downstairs neighbor (I live upstairs in a duplex) telling me someone from DTE was here and needed some information from us. When the dude saw me coming downstairs, he casually waved some badge he had hanging around his neck, and said some vague poo poo about customer service. When I questioned him directly, he said that there had been some complaints about an incorrect charge showing up on everyone's bills, and he'd been sent to make it right, I'd get a credit, whatever. The guy was specifically interested in the gas bill. The gas is shared, and not in my name, but before he found that out, he really, really wanted my DTE account number. I would have sent him packing, buy my neighbor seemed to think it was legit. I think my neighbor did wise up, though. I got a text from him later, saying, "That might have been a scam. Sorry." I'm pretty sure it was, indeed, a scam, but I'm not sure what the end-game was. Was there some scheme to switch us over to another company, or was this the start of a fishing expedition for identity theft, or was it something else, entirely? The dude hadn't asked for any personal information (yet) beyond the account number.
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Apr 24, 2016 12:49
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Centripetal Horse posted:Which scam was this? Google Just energy.
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Apr 24, 2016 13:35
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FadingChord posted:GWM: You don't need to wear clothes if you're out in the woods by yourself and you can save money on toilet paper by just using whatever leaves you pick up nearby! You joke but I'm told Native Americans used Mullein leaves as toilet paper because it's so ridiculously soft. When you touch it, you'll want to rub your rear end all over it as well.
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Apr 24, 2016 14:01
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PCjr sidecar posted:Google Just energy. I'm surprised they're not sued into the ground yet https://www.consumeraffairs.com/utilities/us_energy_savings.html
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Apr 24, 2016 14:34
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ChickenOfTomorrow posted:i hope these young men don't end up horsepoor Subjunctive posted:You can trade anything on margin. Are horse mortgages a thing? It would combine my two favorite BWM themes into one gloriously toxic package 
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Apr 24, 2016 14:49
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Guest2553 posted:Are horse mortgages a thing? It would combine my two favorite BWM themes into one gloriously toxic package Then the horse mortgages can be securitized and tranched! With CDSes on the equity slices!
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Apr 24, 2016 16:55
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Today in "it came from Reddit"... "My boyfriend wants to keep our finances separate forever. I am worried about how HORRIBLE he is with money [28F, 35M]" quote:Together for 3 years. My boyfriend has always said that he will NEVER combine finances with anybody, and all of our money will be separate for the length of our relationship. I am okay with this, though I did suggest we have a "house" account that we each contribute to for emergencies and he didn't want that either. He says his finances are none of my business and vice-versa.
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Apr 24, 2016 18:57
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Those are my favorite people. They believe their modest six-figure income is basically millions, that everyone's trying to get into their pockets and take half. Gotta really look out for their money! So, they refuse to mix financials but then blow their money on every stupid thing imaginable. At least if the girlfriend's hand was in his pants pocket, he gets a HJ. The truck salesman just pulled those pants down and hosed him.
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Apr 24, 2016 19:27
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I love how he's so insistent that they keep separate finances when it's the girlfriend having something to say, but he doesn't mind borrowing money from her. That alone, not even accounting for the fact that they will never be financially stable together, would be enough to immediately dump his rear end.
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Apr 24, 2016 19:40
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NancyPants posted:I love how he's so insistent that they keep separate finances when it's the girlfriend having something to say, but he doesn't mind borrowing money from her. That alone, not even accounting for the fact that they will never be financially stable together, would be enough to immediately dump his rear end. Yeah, that was what stuck out the most to me too. "What's mine is mine, and what's yours is also mine." At least it'll be easy to disentangle herself from this piece of poo poo when she dumps him.
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Apr 24, 2016 19:57
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reddit posted:And this is all that I know about! I know that he makes $7,000 a month after taxes. His monthly bills are around $3500-$4000 and I have no clue where the rest goes. He says he's paying off his debts and has a goal to be debt-free in 4 years, but they haven't gone down at all since we got together. I know he isn't into drugs or gambling. Maybe he has some younger siblings living in poverty, and he secretly supports them financially haha just kidding it's drugs and/or gambling. Come on, if you've been together for 3 years and still can't talk about financial basics, you might as well split up now, cause it's not gonna change in the next 3 years. Or 30.
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Apr 24, 2016 20:16
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CombatInformatiker posted:Maybe he has some younger siblings living in poverty, and he secretly supports them financially haha just kidding it's drugs and/or gambling. Yeah, exactly. Why you would consider even living with someone without coming to full agreement is so beyond me.
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Apr 24, 2016 22:34
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Regardless of the money situation the fact that he owns a $90,000 truck means he's probably an enormous douche manchild so I'm guessing their marriage is going to go fantastic.
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Apr 24, 2016 22:38
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