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I've been reading about some studies and meta-analysis on anti depressant medications. There have been many studies over the years that prove that modern anti-depressant medications preform no better than placebo with mild to moderate depression and only slightly better than placebo with severe depression. Yet they give these drugs out like candy to anyone who comes to them feeling sad about life, despite all the harmful side effects. It has been proven time and time again that SSRI's can cause suicidal idealization in patients, along with a host of other more common unpleasant side effects. And even the patients taking the placebo can experience unpleasant side effects called the "nocebo effect" (although this is rare and largely misunderstood.) The people who are receiving relief from SSRI or other drugs are largely just psychosomatically "curing themselves." This is not science. It needs to change. It seems to me that we should stop proscribing these anti-depressant drugs, except for maybe in the most extreme cases. I feel that psychiatry is in its infancy and many of the treatments of today will be looked upon as absolute quackery by future generations.
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# ? Jun 4, 2016 19:29 |
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# ? May 15, 2024 04:28 |
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Source your quotes.
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# ? Jun 4, 2016 19:31 |
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You should take your meds as prescribed OP.
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# ? Jun 4, 2016 19:32 |
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Thanks for the Scientology manifesto, Tom.
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# ? Jun 4, 2016 19:34 |
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172306/
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# ? Jun 4, 2016 19:38 |
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Brainiac Five posted:http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172306/
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# ? Jun 4, 2016 19:41 |
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AARO posted:I've been reading about some studies and meta-analysis on anti depressant medications. There have been many studies over the years that prove that modern anti-depressant medications preform no better than placebo with mild to moderate depression and only slightly better than placebo with severe depression. Yet they give these drugs out like candy to anyone who comes to them feeling sad about life, despite all the harmful side effects. It has been proven time and time again that SSRI's can cause suicidal idealization in patients, along with a host of other more common unpleasant side effects. And even the patients taking the placebo can experience unpleasant side effects called the "nocebo effect" (although this is rare and largely misunderstood.) The people who are receiving relief from SSRI or other drugs are largely just psychosomatically "curing themselves." This is not science. It needs to change. You didn't take your doses did you?
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# ? Jun 4, 2016 19:42 |
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However, http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804177/
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# ? Jun 4, 2016 19:46 |
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i was diagnosed with mild depression and i cured myself of it with working out and doing sex, ymmv
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# ? Jun 4, 2016 19:46 |
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You lazy research vampires can go ahead and find the studies I'm talking about yourselves that prove these contentions. What I'm saying seems to be totally non-controversial. It's only the application of the studies which are not presently being taking into account. (USER WAS PUT ON PROBATION FOR THIS POST)
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# ? Jun 4, 2016 19:46 |
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I admitted in the OP that the actual drugs do work better than placebo in severe depression. But severe depression accounts for a very small number of the patients prescribed these drugs.
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# ? Jun 4, 2016 19:49 |
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are you telling me i've got to do more than find an abstract that I agree with in order to determine the truth of an assertion? this is bogus i'm going back to hardline religious doctrine to solve my problems
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# ? Jun 4, 2016 19:49 |
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AARO posted:I admitted in the OP that the actual drugs do work better than placebo in severe depression. But severe depression accounts for a very small number of the patients prescribed these drugs. This doesn't refer to severe depression, it refers to analyzing studies conducted of first-generation SSRIs and using reported changes in depressive mood as the yardstick instead of the 57-point scale. It includes patients with moderate and severe depression. Essentially, the conclusion as found in the study is that SSRI antidepressants do have a statistically significant effect when it comes to improving depressive mood over placebo, which in turn suggests that the 57-point scale may be ineffective. Neither is actually conclusive and final when it comes to determining the effectiveness of the treatments, though the meta-analysis does perforate the serotonin reuptake model of depression.
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# ? Jun 4, 2016 19:53 |
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AARO posted:You lazy research vampires can go ahead and find the studies I'm talking about yourselves that prove these contentions. What I'm saying seems to be totally non-controversial. It's only the application of the studies which are not presently being taking into account. I consider myself to be more of a research lich, personally.
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# ? Jun 4, 2016 19:54 |
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AARO posted:You lazy research vampires can go ahead and find the studies I'm talking about yourselves that prove these contentions. What I'm saying seems to be totally non-controversial. It's only the application of the studies which are not presently being taking into account. Bipolar Type I
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# ? Jun 4, 2016 19:55 |
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Angepain posted:are you telling me i've got to do more than find an abstract that I agree with in order to determine the truth of an assertion? this is bogus i'm going back to hardline religious doctrine to solve my problems I've read more than the abstract of these studies. Nowadays, all studies are easily available on the internet.
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# ? Jun 4, 2016 19:56 |
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I was taking a standard SSRI medication for depression. One random night I began experiencing muscle convulsions which grew so severe that my back muscles pulled my left shoulder out of the socket. The upper arm bone came to rest on my shoulderblade and was beaten halfway out of existence. I had to be first sedated to stop the insane muscle contractions (it was similar to being electrocuted in semi-slow motion), and then had to have my shoulder rebuilt using a piece of donor bone. It took me several months to recover. Now I'm sadbrain sometimes but poo poo out of luck. That's my SSRI story.
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# ? Jun 4, 2016 19:57 |
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Brainiac Five posted:This doesn't refer to severe depression, it refers to analyzing studies conducted of first-generation SSRIs and using reported changes in depressive mood as the yardstick instead of the 57-point scale. It includes patients with moderate and severe depression. Essentially, the conclusion as found in the study is that SSRI antidepressants do have a statistically significant effect when it comes to improving depressive mood over placebo, which in turn suggests that the 57-point scale may be ineffective. Neither is actually conclusive and final when it comes to determining the effectiveness of the treatments, though the meta-analysis does perforate the serotonin reuptake model of depression. So what to make of the meta-analysises which prove the opposite?
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# ? Jun 4, 2016 19:58 |
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I used to want to kill myself and now I don't thanks SSRIs
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# ? Jun 4, 2016 20:00 |
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Mister Adequate posted:I used to want to kill myself and now I don't thanks SSRIs Gald you're feeling ok today but it's proven that they may eventually increase your desire to kill yourself at some later point.
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# ? Jun 4, 2016 20:02 |
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AARO posted:So what to make of the meta-analysises which prove the opposite? Well, you didn't read the meta-analysis, then, because the meta-analysis is predicated on the use of the 57-point scale to prove clinical efficacy and the 2015 study challenges the value of the 57-point scale for analyzing depression. AARO posted:Gald you're feeling ok today but it's proven that they may eventually increase your desire to kill yourself at some later point. This is also not in the meta-analysis, though it's (irresponsibly) said in the abstract. Brainiac Five fucked around with this message at 20:04 on Jun 4, 2016 |
# ? Jun 4, 2016 20:02 |
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AARO listen to your doctors. I know you feel good right now but its pretty clear you are afaid and looking to educate yourself made you think you found a revelation, ala you were scared of vaccines so did some googling and now think you know its a scam. Don't be afraid of your condition.
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# ? Jun 4, 2016 20:04 |
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AARO posted:I've read more than the abstract of these studies. Nowadays, all studies are easily available on the internet. i'll admit that post was more based on my general optimism re: the ability of a mean-spirited comedy forum to delve into complex issues of scientific import rather than a specific attack on you, though on the other hand calling people vampires for wanting you to expand on your claims isn't really increasing my optimism any
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# ? Jun 4, 2016 20:09 |
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SSRIs give me super powers and I can see people's Aura's and poo poo so that's cool.
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# ? Jun 4, 2016 20:16 |
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AARO posted:lazy research vampires poo poo, what challenge rating are those?
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# ? Jun 4, 2016 20:16 |
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quote:http://jama.jamanetwork.com/article.aspx?articleid=185157
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# ? Jun 4, 2016 20:18 |
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it's true that SSRIs aren't great but it's not like big pharma is sitting on a better solution, a not great treatment for a disease is better than no treatment at all afaik SSRIs are often perscribed in conjunction with CBT and other forms of therapy
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# ? Jun 4, 2016 20:23 |
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Popular Thug Drink posted:it's true that SSRIs aren't great but it's not like big pharma is sitting on a better solution, a not great treatment for a disease is better than no treatment at all Thank you for this post. This is exactly the type of post I was looking for. I'm not being sarcastic. I just wanted someone to admit that these pills really aren't that great and psychiatric science is in its infancy.
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# ? Jun 4, 2016 20:32 |
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Business Gorillas posted:i was diagnosed with mild depression and i cured myself of it with working out and doing sex, ymmv Drinking socially instead of by myself seems to have a greater than placebo effect as well.
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# ? Jun 4, 2016 20:37 |
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Have you tried cocaine or ecstacy?
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# ? Jun 4, 2016 20:37 |
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foot posted:Have you tried cocaine or ecstacy? You know the problem with rec drugs is they eventually gently caress up your life and cause psychosis. Otherwise this would be the ultimate cure all.
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# ? Jun 4, 2016 20:38 |
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AARO posted:You know the problem with rec drugs is they eventually gently caress up your life and cause psychosis. Otherwise this would be the ultimate cure all. To an extent, so does breathing.
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# ? Jun 4, 2016 20:41 |
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OwlFancier posted:To an extent, so does breathing. If you snort coke everyday for 4 months, you're gonna start having some psychiatric problems. The same cannot be said for breathing.
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# ? Jun 4, 2016 20:45 |
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Only if your doing it right.
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# ? Jun 4, 2016 20:49 |
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More like $$RIs.
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# ? Jun 4, 2016 20:58 |
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Peven Stan posted:More like $$RIs. I don't care if you're being serious or not. If they actually did what they're purported to do they'd be worth every penny.
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# ? Jun 4, 2016 21:01 |
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agreed op, they are overprescribed but also clinically useful in some cases
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# ? Jun 4, 2016 21:18 |
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AARO posted:Gald you're feeling ok today but it's proven that they may eventually increase your desire to kill yourself at some later point. Well if I'm gonna do it either way better later than sooner!
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# ? Jun 4, 2016 21:19 |
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there's always alcohol
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# ? Jun 4, 2016 21:19 |
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# ? May 15, 2024 04:28 |
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once i was prescribed xanax and threw out the whole bottle unused. then i moved out of the PNW and enjoyted life again
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# ? Jun 4, 2016 21:22 |