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Murray Mantoinette posted:Part of the problem is that if you want approval for an antibiotic from, e.g., the FDA, or to get a patent, you need to give them the chemical structure and often a method for synthesis. The info is now public The singing rear end in a top hat outside my building finally stopped. He was singing all those hours without any break or slow down. I guess peeing is not a problem snce nobody drinks water here. I have a feeling he will be back after dinner.
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Jan 25, 2017 11:44
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What's the appeal of doing karaoke outside, on a street corner? I guess I could understand in a park, but...
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Jan 25, 2017 12:34
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Unrestrained and burning hatred for your fellow man. Hey, somebody might even drop a few rambos on the way.
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Jan 25, 2017 13:19
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barbecue at the folks posted:2 or 3 out of 5 of our grandkids are gonna be dying from formerly easily treatable diseases like tuberculosis, like it was the 19th century all over again. There was an article on the paper today on how China casually uses colistin to treat livestock in massive amounts, ruining the only really effective antibiotic left for the whole planet. After antibiotics are finally done for, the plagues begin. Really Trump starting a trade war, or regular war with china is basically just self defence at this point.
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Jan 25, 2017 13:48
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nickmeister posted:What's the appeal of doing karaoke outside, on a street corner? I guess I could understand in a park, but... The city is legitimately quiet now all day. It is amazing and beautiful. If Shenzhen was always like this, I would be living in the best place in China. I was walking across 8-lane roads on the green lights because the cars were so sparse. The park that is usually hell on weekends and days-off was empty and calm. I even saw another white guy tanning on a blanket, able to be shameless since there were no gawkers around. Because it's a holiday, the people that are here are not working and are mostly drunk by sunset. I kanrenao'd two separate drunk people screaming matches on the sidewalk. The good one was one guy sitting in his car with the windows rolled up, hanging his head in shame, while an old man was shouting as loud as possible and pointing at the guy, while a younger girl limply pretending to pull him away. I guess the fake arm pulling stuff is a Face thing? They all do it here. The BBW sent me a message showing me the huge amount of alcohol she bought for the Spring Festival party she is forced to throw for her family. She went to HK and bought a case of wine, boxes of imported German beers, and came back to Mainland and bought a giant box of RIO. I was confused they she had harder stuff, but then a ton of RIO.  The RIO is for her daughter. Her daughter is 11.
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Jan 25, 2017 15:42
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Beachcomber posted:Could we just not tell them the next time we develop one? Colistin is actually an old antibiotic. We didn't use it very much because it has bad side effects. The idea that we can just make new antibiotics is not sound either. There are realistically only so many chemicals we can come up with that are poison for bacteria but also don't kill us -- bacteria share a lot of our essential biological machinery after all. In a perfect world antibiotic use would be forbidden for anything non-human (maybe with an exception for pets) and there'd be a governing body that rotated one family of antibiotics out of use every 15-20 years. Drug resistance is metabolically very expensive for a bacterium and the ones that don't have it will outcompete the ones that do given some time and the right (certain antibiotic free) environment. You also have to go by family of antibiotic. Some antibiotics work in a very similar way and therefore the resistance mechanism bactria develop is similar or the same for the whole family (slime layer to prevent attachment to the cell wall, enzyme/protein production that digests/corrupts an antibiotic, etc). The downsides would be meat would be much more expensive as animal density can only go so high before regular antibiotics become necessary, and also antibiotics would become slightly more expensive. The second issue could be helped if it wasn't only doctors that could issue them, make pharmacists able to do so too, but audit them regularly and if they aren't doing due diligence yank their license. This would mean pharmacists would have to do tests occasionally which means some procedures to collect the material to test (or sending the patient to the hospital or clinic for certain tests for infections) but you could give them all the skills they need for that in a one semester class in college and a little on the job training, there's not a lot to it. raton fucked around with this message at 16:03 on Jan 25, 2017 |
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Jan 25, 2017 15:57
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Sheep-Goats posted:The idea that we can just make new antibiotics is not sound either. There are realistically only so many chemicals we can come up with that are poison for bacteria but also don't kill us -- bacteria share a lot of our essential biological machinery after all. Not quite. You can easily stumble upon numerous antibiotic compounds in nature. Profiting off of researching antibiotics is really difficult so not a lot of people do it. Even if you do it you only have a tiny window, 2-3 years after release of a new antibiotic compound, until the first resistant organisms crop up.
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Jan 25, 2017 16:04
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nickmeister posted:What's the appeal of doing karaoke outside, on a street corner? I guess I could understand in a park, but... Blind people often stumble around in pairs in Bangkok, the guy plays a little instrument, the woman sings, both things are amplified by a small speaker hanging around the guys neck. I didn't see that in Harbin and the Chinese I'm sure have a few different begging traditions but "he's blind so he can only do music or massage" is a belief that probably 80% of our most populous continent shares.
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Jan 25, 2017 16:07
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Blind massage is a thing here in Taiwan but I don't see the blind street music. It's sold as "they're better at massage since they can't see!" Like they're Daredevil or something.
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Jan 25, 2017 16:09
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Pirate Radar posted:Blind massage is a thing here in Taiwan but I don't see the blind street music. It's sold as "they're better at massage since they can't see!" Like they're Daredevil or something.
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Jan 25, 2017 16:55
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Boiled Water posted:Not quite. You can easily stumble upon numerous antibiotic compounds in nature. Profiting off of researching antibiotics is really difficult so not a lot of people do it. We've been searching for these fairly aggressively for decades. I'm not saying there aren't more out there but biological compounds have the same issue with antibiotic utility that man made ones would. We cannot expect there to always be new antibiotics for us to find and even if there were infinite solutions to the chemical puzzle of "kills the gently caress out of bacteria, doesn't bother people that much", which there are definitely not, we would expect to find them at exponentially increasing periods of time. At some point it has to become about managing what we have, and honestly that point was probably some time in the 1980s.
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Jan 25, 2017 18:08
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I asked a Chinese girl for her number she said "Sex! Sex! Sex! Free sex tonight!" I said "Wow!" Then her friend said "She said 666-3629"
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Jan 25, 2017 23:41
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Ein cooler Typ posted:I asked a Chinese girl for her number Go home dad, you are drunk
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Jan 26, 2017 00:16
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I once read a great article about how when the Soviet Union collapsed and infrastructure was breaking down there were researchers in Almaty that saved a bunch of phages from dying out by storing them in their fridges at home
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Jan 26, 2017 02:39
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Jan 26, 2017 02:56
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I for one am looking forward to the glorious future of injecting bacteriophages into people to cure diseases
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Jan 26, 2017 02:57
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so it's ok to take drugs, or go whoring, as long as you don't do both
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Jan 26, 2017 03:07
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Haier posted:Some idiot has been on the street corner with a portable karaoke box singing very loudly and very poorly for at least two hours now. It's a beautiful sunny day but I have stuff to do and can't just leave where I am. I hate how there are no rules or laws here about public noise (or never enforced if there are). Every shop has a speaker blasting lovely music or ads 14 hours a day and nobody cares. There's never any peace and I am sure it contributes to people's mental "edge," including my own. do you enjoy Barber Shop Techno
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Jan 26, 2017 04:04
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That's so racist. "Only we Chinese are allowed to take ketamine and go whoring at the local KTV. You Foreigners cannot do such a thing!"LentThem posted:do you enjoy Barber Shop Techno
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Jan 26, 2017 04:37
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Jan 26, 2017 05:03
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Also the wall was mostly built by the Ming and we know how that turned out for them.
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Jan 26, 2017 05:24
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Otoh, that wall might keep southamerica safe when the zombieapocalypse happens.
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Jan 26, 2017 07:25
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this is like the chinostalgia thread
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Jan 26, 2017 07:46
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I hope they make it fluorescent pink
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Jan 26, 2017 07:59
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I only follow the Western rules: 420 take drugs while whoring erry day
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Jan 26, 2017 08:03
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Haier posted:The city is legitimately quiet now all day. It is amazing and beautiful. If Shenzhen was always like this, I would be living in the best place in China. I was walking across 8-lane roads on the green lights because the cars were so sparse. The park that is usually hell on weekends and days-off was empty and calm. I even saw another white guy tanning on a blanket, able to be shameless since there were no gawkers around. Population density is hell. Thats why I love living in the nordics.
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Jan 26, 2017 08:19
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I'm also goony as hell so I can't stand it either, unfortunately living in Flanders.
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Jan 26, 2017 08:21
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Stink Billyums posted:Also the wall was mostly built by the Ming and we know how that turned out for them. mercilessly?
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Jan 26, 2017 08:22
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Every once in a while I get a phone call from a wrong number (or repeated calls from the same clueless person). Every time I answer, the other person immediately starts jabbering without any delay for someone to greet them or verify if they have the correct number (or maybe if someone even answered the call). If I answer it and say nothing, the other person will talk for 5+ seconds before realizing there is nobody there, and then repeatedly ask questions for another 5-10 seconds before hanging up. Other times I will answer, let them blab, and then say "AHHHH?" in a cartoony voice, to which the other person immediately ends the call. There has never been any change in this; it's exactly the same routine every time. I always answer my phone with an ambiguous "AH?" or "EHHHHHH???????" because I have had the experience with a wrong number and answer "Hello," and then the person calling every day to try to practice English (as well as suddenly several more people calling me to practice English, because the person probably gave out my phone number to other people). Fojar38 posted:I hope they make it fluorescent pink
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Jan 26, 2017 09:26
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Haier posted:I'm just curious what that brown stain is on the left side. You know what it is...
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Jan 26, 2017 10:36
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Ok who is the Swedish goon who came up to talk with me on the way to the Star Ferry?
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Jan 26, 2017 11:44
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Jan 26, 2017 12:24
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After years of these jokes, I'd try it. Hearing jokes about dog-eating is kind of like hearing about eating dog. Bit of an unintended side-effect.
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Jan 26, 2017 12:52
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Accretionist posted:After years of these jokes, I'd try it. dog is good and tasty
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Jan 26, 2017 13:32
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EXXXTREME FACE LOSS: Cashier rings up my purchases. It comes to a total of 54 RMB - Her: *Trying to speak English* "... Four... Forty.... five!" Me: "Very good! The numbers are the other way - Five - Fifty.. four." Her: *Scowls and shoots daggers at me with her eyes* Me: *Give her 55 RMB* Her: *Throws the coin back at me instead of handing it at me, and doesn't thank me like they always do in this supermarket*
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Jan 26, 2017 14:58
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Still gets an 11:00pm call from the in-hotel "massage" service.
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Jan 26, 2017 15:45
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Diving into TCM and the wonders of taoism, it stroke me that every orifice of my body was leaking lifeforce! Ofc some ingenious mind thought up a solution for that problems centuries ago. China wins again! ~Nsfw~ Better plug up ~Nsfw~
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Jan 26, 2017 17:31
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Haier posted:EXXXTREME FACE LOSS: Every white person naturally speaks English.
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Jan 26, 2017 17:58
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Haier posted:Every once in a while I get a phone call from a wrong number (or repeated calls from the same clueless person). Every time I answer, the other person immediately starts jabbering without any delay for someone to greet them or verify if they have the correct number (or maybe if someone even answered the call). If I answer it and say nothing, the other person will talk for 5+ seconds before realizing there is nobody there, and then repeatedly ask questions for another 5-10 seconds before hanging up. Other times I will answer, let them blab, and then say "AHHHH?" in a cartoony voice, to which the other person immediately ends the call. There has never been any change in this; it's exactly the same routine every time.
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Jan 26, 2017 18:07
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If I download WeChat and start hitting up every FOB in NYC for Chinese lessons, how well do you think it would go over?
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Jan 26, 2017 20:42
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