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Who is your first pick in the deputy leadership race?
This poll is closed.
R. Allin-Khan 6 1.60%
R. Burgon 80 21.33%
D. Butler 72 19.20%
A. Rayner 35 9.33%
I. Murray 5 1.33%
P. Flaps 177 47.20%
Total: 375 votes
[Edit Poll (moderators only)]

 
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mediaphage
Mar 22, 2007

Excuse me, pardon me, sheer perfection coming through

Communist Thoughts posted:

https://academic.oup.com/nsr/advance-article/doi/10.1093/nsr/nwaa036/5775463


Not really arguing here, just there does seem to be evidence of divergence. presumably a vaccine or secondary immunity would still resist both.
there was also some more recent stories about a mutation in the spikes in the italian covid but i dunno if that refers to the same L strain or whatever

Cheers, I missed this; thanks for the link. It's definitely true that "minor" changes can have an impact on how it hits a host; I still feel confident that they won't impact potential vaccines or antivirals too much.

Communist Thoughts posted:

thats a nice way of putting it

but imo they're basically alive, its like species where we just make up an arbitrary delineation between things that doesnt exist in nature for the purpose of categorisation then argue with ourselves about it as if its a fundamental law

I disagree that it's arbitrary; the key distinction that makes most biologists think of viruses as not being alive is that they lack any kind of replication ability without undermining a host's cellular biochemistry. Are mitochondria alive? Chloroplasts? What about prions? Predatory chemistry is unbelievably apt.

Snypedit: Trump says that he has a 78% approval rating for his presidency thanks to his strong and forward-thinking corona response.

mediaphage fucked around with this message at 13:44 on Mar 14, 2020

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Strom Cuzewon
Jul 1, 2010

At a-level viruses were "bad-news in a protein coat".

I find it funny that computer viruses were named as an analogy to biological viruses, but in modern times the analogy is way more useful the other way round. Viruses are bits of broken code that hijack your OS.

Communist Thoughts
Jan 7, 2008

Our war against free speech cannot end until we silence this bronze beast!


mediaphage posted:

Cheers, I missed this; thanks for the link. It's definitely true that "minor" changes can have an impact on how it hits a host; I still feel confident that they won't impact potential vaccines or antivirals too much.


I disagree that it's arbitrary; the key distinction that makes most biologists think of viruses as not being alive is that they lack any kind of replication ability without undermining a host's cellular biochemistry. Are mitochondria alive? Chloroplasts? What about prions? Predatory chemistry is unbelievably apt.

Snypedit: Trump says that he has a 78% approval rating for his presidency thanks to his strong and forward-thinking corona response.

yeah i do get that its cause they don't have the machinery to reproduce themselves

but lets not kink shame the poor things

are mitochondria alive is another can of worms, free the slaves!

e: i'd have thought a prion is considerably less complex than a virus. is that not the case? i know proteins get pretty wild sometimes

Flipswitch
Mar 30, 2010


JeremoudCorbynejad posted:

I now want a version of Prison Architect where it's Hospital Architect and it's in the middle of an epidemic. Ever increasing numbers of patients arriving and you have to install beds in corridors, supply closets, or out on the goddamn pavement
Try Frostpunk and just build more snowpits. :v:

feedmegin
Jul 30, 2008

goddamnedtwisto posted:

Weird thing around here is that all the big shops have empty bogroll shelves but all the little ones have tons. I'm assuming there's going to be some fascinating psychological papers about this at some point.

Similarly, Barking Asda has been totally bought out of rice - even the 10kg sacks in the World section - but my local Egyptian-Turkish-Bulgarian shop has plenty. Also things like paper towels and yeast etc.

My theory is that all the Hyacinth Bucket types are now just about panicked enough to buy the rice with the scary foreign writing on from the supermarket, but going into a store run by those ethnics is still a step too far.

More fool them. I have 5kg of rice and a bunch of red beans and they do not, some of which is in the slow cooker as we speak. :chef:

Guavanaut
Nov 27, 2009

Looking At Them Tittys
1969 - 1998



Toilet Rascal

mediaphage posted:

that they lack any kind of replication ability without undermining a host's cellular biochemistry.
What about the 40-50% of life that is parasitic, and the 20% that is parasitic to the degree that it can't replicate without undermining a host's cellular biochemistry?

Are Rhizocephala alive? Or Liriopsis pygmaea?

There's a lot of blurred edges around the distinctions, but tbh being reminded of the existence of those creatures makes me think that we should redefine 'life' as "a bad idea, to be avoided."

Strom Cuzewon posted:

At a-level viruses were "bad-news in a protein coat".
Sounds more like Costa sausages.

Mebh
May 10, 2010


Aidan_702 posted:

What was so good about it? Pls note I hate anything with vinegar in it so you’re on thin ice

I just grind my own ribeye, heat a cast iron to smoking brush with a little oil, form the meat into loose balls, then do two at a time on the pan and smash thin. Put salt and pepper on, flip after 90s, put salt and pepper on and a slice of cheese wait for 60s remove.

I fried brioche Buns in butter on a pancake griddle.

Then I just assemble them to order for folks. First batch was standard, thinly sliced tomato. Pickled Jalapeños, those American cheese slices, ketchup and mayo.

Second batch I did crumbled Feta, Red onions, tomatoes, a tiny bit of balsamic glaze and a little scrape of perinaise.

Jose
Jul 24, 2007

Adrian Chiles is a broadcaster and writer
sainsburys own brand extra virgin olive oil was fully out of stock except for 1 2L metal tub i bought when I went and the toilet roll entirely out of stock although they were hastily restocking it by the time I was leaving. Frozen veg was pretty barren too but at least that makes sense

thats my saturday supermarket trip report

Communist Thoughts
Jan 7, 2008

Our war against free speech cannot end until we silence this bronze beast!


Mebh posted:

I just grind my own ribeye, heat a cast iron to smoking brush with a little oil, form the meat into loose balls, then do two at a time on the pan and smash thin. Put salt and pepper on, flip after 90s, put salt and pepper on and a slice of cheese wait for 60s remove.

I fried brioche Buns in butter on a pancake griddle.

Then I just assemble them to order for folks. First batch was standard, thinly sliced tomato. Pickled Jalapeños, those American cheese slices, ketchup and mayo.

Second batch I did crumbled Feta, Red onions, tomatoes, a tiny bit of balsamic glaze and a little scrape of perinaise.

hissing at brioche buns tbh

sounds good though, i'd eat the hell outta those second ones.
i've started doing the making burgers from steaks thing but i dont have a grinder so i just pound the crap outta them with a cleaver for 10 minutes while my neighbours swear

Jose
Jul 24, 2007

Adrian Chiles is a broadcaster and writer
If you cut the meat into cubes for half an hour you can use a food processor and get something close to grinding

Communist Thoughts
Jan 7, 2008

Our war against free speech cannot end until we silence this bronze beast!


Jose posted:

sainsburys own brand extra virgin olive oil was fully out of stock except for 1 2L metal tub i bought when I went and the toilet roll entirely out of stock although they were hastily restocking it by the time I was leaving. Frozen veg was pretty barren too but at least that makes sense

thats my saturday supermarket trip report

i havent been out of quarantine since monday, but luckily i bought all the loo roll in scotland so i should be good for about as long as itll take society to grind to a halt and then im gonna start dragging my bum on the carpet like a dog

OwlFancier
Aug 22, 2013

Why wait?

Jose
Jul 24, 2007

Adrian Chiles is a broadcaster and writer

Communist Thoughts posted:

i havent been out of quarantine since monday, but luckily i bought all the loo roll in scotland so i should be good for about as long as itll take society to grind to a halt and then im gonna start dragging my bum on the carpet like a dog

As a contractor who won't get paid if he isn't working I'll only quarantine if I get made to. Going to go to the gym soonish though

Oodles
Oct 31, 2005

I’m in a house of 5 women. Bog roll doesn’t stand a chance here.

Jose
Jul 24, 2007

Adrian Chiles is a broadcaster and writer
Anyway I'm treating this with all the seriousness I treated the hurricane and I'm basically certain to catch it living with a doctor lol

OwlFancier
Aug 22, 2013

Looking forward to the interview with a viscous, pulsating mass of virus a foot up your patio door.

mediaphage
Mar 22, 2007

Excuse me, pardon me, sheer perfection coming through

Guavanaut posted:

What about the 40-50% of life that is parasitic, and the 20% that is parasitic to the degree that it can't replicate without undermining a host's cellular biochemistry?

Are Rhizocephala alive? Or Liriopsis pygmaea?

There's a lot of blurred edges around the distinctions, but tbh being reminded of the existence of those creatures makes me think that we should redefine 'life' as "a bad idea, to be avoided."

Sounds more like Costa sausages.

Obligate parasites still replicate on their own, even if they require a very specific environment to do so.

Communist Thoughts
Jan 7, 2008

Our war against free speech cannot end until we silence this bronze beast!


typhoid jose
going to the gym when you almost certainly have/will have it isn't very prosocial of you!


Oodles posted:

I’m in a house of 5 women. Bog roll doesn’t stand a chance here.

trying to explain to my girlfriend to just shake her hind quarters

Jose
Jul 24, 2007

Adrian Chiles is a broadcaster and writer
This whole video on what China did and Italy are having to do owns and will scare you about Italy

https://twitter.com/MikeIsaac/status/1238604080571772928?s=19

Melissa McCarthyism
Jan 18, 2007

What's the guidance for people stuck in another country? My mate and his wife are now stranded in Poland.

ThomasPaine
Feb 4, 2009

We have no compassion and we ask no compassion from you. When our turn comes, we shall not make excuses for the terror.
I've reread this about five times and I honestly can't tell which part of the tweet is objectionable even from the mindset of the brainwormed.

This is just... objectively correct?

https://twitter.com/J_Bloodworth/status/1238813063727497217?s=20

Jose
Jul 24, 2007

Adrian Chiles is a broadcaster and writer
isn't bloodworth part of the oz katerji crowd so just a massive oval office with likely ties to the security services?

kyojin
Jun 15, 2005

I MASHED THE KEYS AND LOOK WHAT I MADE

No More Toast posted:

I have no idea and can't help but think the guidance is purposefully vague.

I've had a sore throat for the last couple of days and have woken up with a bit of a tickly cough. It isn't a bad cough, I'm not doubled over coughing for minutes or coughing constantly, but it's still a cough. I feel fine mostly, my nose feels a bit congested (although isn't actually blocked) and definitely don't have anything approaching flu-like symptoms.

This is an exact description of what I am experiencing, for about a week now. Very slight headache, but no fever. I had one day of a lot of congestion in my nose on about Wednesday but otherwise same as you, and that could have been hay fever. Is this a possibility for the mild reaction or do I just have a different common cold? I've been at home since last Friday because I feel a sense of responsibility to not loving infect anyone, even more so since I found out I'm ruining their evil plan by doing so.

I wish I could get tested rather than just sitting around my house speculating anxiously, even if it took a week to get the results because they are prioritising more severe cases, fair enough.

I'm unemployed currently but I have an interview on Monday morning, I'm considering walking nine miles rather than take the tube but maybe it's better to just bail, it won't be impossible for me to find another job.


clear eyes full farts posted:

Guidelines are no ventilators for patients over 55, when it gets really bad that will drop to 40, grim


I'm 40 and this just cranked my anxiety 8000% cool. I know I'm still extremely unlikely to need it but loving hell.

Darth Walrus
Feb 13, 2012

ThomasPaine posted:

I've reread this about five times and I honestly can't tell which part of the tweet is objectionable even from the mindset of the brainwormed.

This is just... objectively correct?

https://twitter.com/J_Bloodworth/status/1238813063727497217?s=20

China stopped being socialist in any meaningful way a few decades back, so they may not be the best example, and I'm not sure about 'Nam's socialist credentials these days, either.

Fumble
Sep 4, 2006
Probation
Can't post for 17 days!

Melissa McCarthyism posted:

What's the guidance for people stuck in another country? My mate and his wife are now stranded in Poland.

Drink heavily until it blows over.

Guavanaut
Nov 27, 2009

Looking At Them Tittys
1969 - 1998



Toilet Rascal

mediaphage posted:

Obligate parasites still replicate on their own, even if they require a very specific environment to do so.
But they have to change the cellular biochemistry of their hosts in order to make that environment.

You could define life as "do they contain a full genome capable of self-replication", and that would include most parasites and exclude viruses, prions, mitochondria, and chloroplasts. Status of Mycoplasma laboratorium is ???

Jaeluni Asjil
Apr 18, 2018

Sorry I thought you were a landlord when I gave you your old avatar!

Melissa McCarthyism posted:

What's the guidance for people stuck in another country? My mate and his wife are now stranded in Poland.

„Chodźmy do Winchester, napijmy się zimnego kufla i poczekaj, aż wszystko się rozwali”.

Jaeluni Asjil
Apr 18, 2018

Sorry I thought you were a landlord when I gave you your old avatar!

Oh dear me posted:

Right, that's me and Jaeluni doomed then.

:(

ThomasPaine
Feb 4, 2009

We have no compassion and we ask no compassion from you. When our turn comes, we shall not make excuses for the terror.

Darth Walrus posted:

China stopped being socialist in any meaningful way a few decades back, so they may not be the best example, and I'm not sure about 'Nam's socialist credentials these days, either.

Sure but China's socialism/lack of socialism is kinda a different topic though. He's obviously using 'socialism' as a stand-in for 'interventionist big state government', which I admit isn't ideal for its own reasons, but I don't think that's what Bloodworth's picking up on.

e: fwiw I'm mostly skeptical of everything written on China in the West. I think they think they're socialist, but they're going about it in a dogmatic and super flawed way that has then also been influenced by some fairly conservative aspects of Chinese culture. I don't think that's any reason to doubt their sincerity though. You look at someone like Xi's life and he pretty obviously considers himself a communist and has also put the graft into learning his theory. So I'm kind of in the position where I can think they're loving it up but still feel genuinely inspired by the fact that they believe in something. That sense of optimism and purpose and community-mindedness has come across to me in many conversations with (mainland) Chinese friends and colleagues, and tbqh it's loving intoxicating by comparison to places like the UK where everyone's alienated and miserable and nobody cares about anything but the most superficial bullshit and it's just work and consume till you die, more blood for the blood god, number must go up.*

*Yes, Chinese policy direction since Deng has been quite 'number must go up' too, but as the pandemic response shows this is understood in completely different terms. Capitalism isn't a governing ideology but the CPC are attempting to harness the power of capitalism to their own ends without needlessly deferring to it at all times. Hence why you can just shut down an entire city and mobilise insane resources where necessary.

ThomasPaine fucked around with this message at 14:42 on Mar 14, 2020

Bardeh
Dec 2, 2004

Fun Shoe
a bloke just keeled over and died in my local tesco :wtf: who knows if it's virus related but loving hell

TheRat
Aug 30, 2006

Bardeh posted:

a bloke just keeled over and died in my local tesco :wtf: who knows if it's virus related but loving hell

There were rumours coming out of Hubei in like january of people just falling over and dying in the streets, but it was mostly dismissed as conspiracy nuttery.

jabby
Oct 27, 2010

I know I haven't been in the thread much since the election, but I just wanted to give you a quick medical update:

:piss:

Mebh
May 10, 2010


Communist Thoughts posted:

hissing at brioche buns tbh

sounds good though, i'd eat the hell outta those second ones.
i've started doing the making burgers from steaks thing but i dont have a grinder so i just pound the crap outta them with a cleaver for 10 minutes while my neighbours swear

Yeah they were what my guests brought, I don't see the obsession. They're too sweet. I haven't gravitated to making my own buns yet as that's really pushing the effort too far.

I'd totally recommend a cheap grinder though. Means I can take £10 of ribeye and process it into mince for about 9 patties? I slightly freeze the steaks before I grind them and it takes about 30s. Never going back.

Guavanaut
Nov 27, 2009

Looking At Them Tittys
1969 - 1998



Toilet Rascal

jabby posted:

I know I haven't been in the thread much since the election, but I just wanted to give you a quick medical update:

:piss:
Thank you for your service.

Time to retreat to the toilet roll fort then?

Comrade Fakename
Feb 13, 2012


Aidan_702 posted:

https://youtu.be/wZ9J-dxEgY4

Can we just pin this to the OP please

I love that a nuclear bomb going off in New York is so low key in that video. “Holy poo poo remember when a building burned down in Brussels?! Oh yeah New York got nuked that happened too.”

OwlFancier
Aug 22, 2013

jabby posted:

I know I haven't been in the thread much since the election, but I just wanted to give you a quick medical update:

:piss:

Glad you're not dead, was a bit worried tbh.

CGI Stardust
Nov 7, 2010


Brexit is but a door,
election time is but a window.

I'll be back

jabby posted:

I know I haven't been in the thread much since the election, but I just wanted to give you a quick medical update:

:piss:
Good luck to you and all other medical goons. Stay safe :ohdear:

thespaceinvader
Mar 30, 2011

The slightest touch from a Gol-Shogeg will result in Instant Death!

Communist Thoughts posted:

e: i'd have thought a prion is considerably less complex than a virus. is that not the case? i know proteins get pretty wild sometimes

Yes, prions are way less complex, they're literally just proteins, no DNA or RNA, just badly folded proteins that when they interact with the well folded ones, somehow cause them to fold badly.

Prions are loving WILD and I still wonder whether I'm going to come down with CJD at some point in the next decade or so. Thanks Maggie.

ThomasPaine
Feb 4, 2009

We have no compassion and we ask no compassion from you. When our turn comes, we shall not make excuses for the terror.
I'm don't take any pleasure in it but bodies in the street and mass graves (and not just amongst the poor!) can only do the British national consciousness good in the long run. I've said it before, but I think one of the major reasons for this absurd sense of exceptionalism we have and general belief that nothing really bad could happen here is down to Britain never being directly invaded in WW2. Every other country in Europe has been under occupation and has seen cities become warzones and mass death, whereas we got the blitz which was, while bad, a drop in the ocean by comparison. It's exactly the same story with the USA. The only thing that's going to get rid of that frankly dangerous attitude is being made to sit and watch as it does happen here.

And even then they'll probably still vote Tory.

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Failed Imagineer
Sep 22, 2018

Guavanaut posted:

But they have to change the cellular biochemistry of their hosts in order to make that environment.

You could define life as "do they contain a full genome capable of self-replication", and that would include most parasites and exclude viruses, prions, mitochondria, and chloroplasts. Status of Mycoplasma laboratorium is ???

In undergrad biology we had some philosophy bits, where you could basically end up with a definition of life that includes "fire"

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