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Owlofcreamcheese posted:It was, but he got all mad about it recently out of no where, because of This was also posted on september 1st
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Oct 8, 2020 00:19
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Did he seriously say it’s a gift from god? That’s gonna kill so many chuds lol
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Oct 8, 2020 00:37
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BobTheJanitor posted:This was also posted on september 1st Yes. That is why trump was suddenly talking about months old events
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Oct 8, 2020 00:38
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One thing that jumped out at me in the TWiV podcast about Regeneron's REGN-COV2 monoclonal antibody treatment was that it's made from "humanized" mice. Can you imagine any of the GOP voters being in favor of such a thing? Like that's the sort of thing the GOP would try to cancel research grants over and ban at a federal level. But their dumb reality show character president got pumped full of humanized mouse cells.
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Oct 8, 2020 00:57
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7of7 posted:One thing that jumped out at me in the TWiV podcast about Regeneron's REGN-COV2 monoclonal antibody treatment was that it's made from "humanized" mice. Humanized mice?? https://www.youtube.com/watch?v=oRIyw-pJkUk
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Oct 8, 2020 01:01
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7of7 posted:One thing that jumped out at me in the TWiV podcast about Regeneron's REGN-COV2 monoclonal antibody treatment was that it's made from "humanized" mice. Isn’t that the thing where they make human-mouse hybrid cells? The god botherers would lose their poo poo over that
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Oct 8, 2020 01:07
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gay picnic defence posted:Isn’t that the thing where they make human-mouse hybrid cells? The god botherers would lose their poo poo over that Bush W lost his poo poo over it and introduced a bill to stop labs from doing that back in 06. No one had any idea what the gently caress he was talking about and eventually every scientist had to explain "No. Some pharmaceutical labs make mice grow human cells because it's a cleaner way to experiment on live humans. No one is making ManSharks to create a perfect army to attack and dethrone God"
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Oct 8, 2020 01:12
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Trump will be about 12 days away from first showing symptoms this coming Monday. He will likely still be testing positive and shedding the virus. And they’re planning for him to do an event in Pittsburg. This is loving out of control.
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Oct 8, 2020 01:14
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gay picnic defence posted:Isn’t that the thing where they make human-mouse hybrid cells? The god botherers would lose their poo poo over that Yeah it's mouse B cells that produce the antibody smashed together with human cancer cells to make them immortal. https://en.wikipedia.org/wiki/Monoclonal_antibody https://en.wikipedia.org/wiki/Hybridoma_technology They're not humanising mice, just some cells from their spleen. Edit: also this is super, super, common. A huge range of medical tests rely on this technology.
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Oct 8, 2020 01:17
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Shimrra Jamaane posted:Trump will be about 12 days away from first showing symptoms this coming Monday. He will likely still be testing positive and shedding the virus. And they’re planning for him to do an event in Pittsburg. This is loving out of control.
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Oct 8, 2020 01:26
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Shimrra Jamaane posted:Trump will be about 12 days away from first showing symptoms this coming Monday. He will likely still be testing positive and shedding the virus. And they’re planning for him to do an event in Pittsburg. This is loving out of control. Sounds like perfect timing for the later phases of covid to kick in and have him collapse on stage due to ARDS in front of 10,000 screaming chuds
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Oct 8, 2020 01:34
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Lead out in cuffs posted:Yeah it's mouse B cells that produce the antibody smashed together with human cancer cells to make them immortal. Most places I've looked have referred to Regeneron's technology as literally "humanizing" mice which seems to refer to actually genetically modifying them to have a more human immune system so that the antibodies they produce are more human. This paper from Regeneron about the Covid antibody treatment links to this other one describing how they genetically modify the mice.
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Oct 8, 2020 01:35
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Basically, the old way of making a monoclonal antibody is to inject the antigen (the coronavirus spike) into a mouse, then taking the B cells and fusing them with special tumor cells to form a hybridoma. You then isolate clones of these hybridomas, to screen for a clone that produces your specific monoclonal antibody. But all you're making are mouse antibodies, and putting a mouse antibody into a human will just make the human make anti-mouse antibodies, rendering your drug non-functional. Therefore usually the second step is to humanize the mouse antibody, by swapping out parts of that mouse antibody with parts from a human antibody, forming a "chimeric" antibody that is "invisible" to the human immune system. What we do now is humanize the mouse from the get-go. So the mouse will be genetically engineered to have human antibody genes, so that the final product looks like a fully human antibody. Much much faster.
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Oct 8, 2020 03:31
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7of7 posted:One thing that jumped out at me in the TWiV podcast about Regeneron's REGN-COV2 monoclonal antibody treatment was that it's made from "humanized" mice. During the Bush years they tried to make a stink about "Chimeras" and I think they even passed a law to ban them
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Oct 8, 2020 03:43
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HappyHippo posted:During the Bush years they tried to make a stink about "Chimeras" and I think they even passed a law to ban them How could you let this happen!? Edit: Boo, couldn't get the embed to work, imagine I posted the obvious FMA image 
BougieBitch fucked around with this message at 04:06 on Oct 8, 2020 |
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Oct 8, 2020 04:00
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HappyHippo posted:During the Bush years they tried to make a stink about "Chimeras" and I think they even passed a law to ban them Brownback tried after Bush mentioned it in a state of the union, but the bill died. Republicans are afraid chimera means "the dog man from Invasion of the Body Snatchers" or "The Island of Dr. Moreau."
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Oct 8, 2020 04:11
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Chimeras are mentioned in the book of revelation as something horrible. So it's just christian nonsense, although at least it's them trying to prevent the end of the world, unlike... you know, the rest.
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Oct 8, 2020 04:35
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Grondoth posted:Chimeras are mentioned in the book of revelation as something horrible. So how do you reconcile that with the "support Israel as much as possible to bring about the apocalypse" mindset?
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Oct 8, 2020 04:54
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Eric Cantonese posted:So how do you reconcile that with the "support Israel as much as possible to bring about the apocalypse" mindset? You don't! The most politically influential religious sect in america is literally trying to bring about the end of the world! It feels like something we all should be horrified about, but it's just a political reality since the 1970s!
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Oct 8, 2020 04:57
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Eric Cantonese posted:So how do you reconcile that with the "support Israel as much as possible to bring about the apocalypse" mindset? Bad things happen to Those people over There is OK
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Oct 8, 2020 05:40
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gay picnic defence posted:Isn’t that the thing where they make human-mouse hybrid cells? The god botherers would lose their poo poo over that Evangelicals are morally opposed to whatever it is convenient to morally oppose. They so vehemently oppose abortion and gay marriage, for example, because it permits them to feel morally superior to everyone else by literally doing nothing - moral opposition does not come any more conveniently than that. Where their "moral principles" stand in the way of earthly gain, they invariably jettison them with astonishing alacrity (See: Trump, Donald J., election of). If Trumps' slurping down human-mouse hybrids made from fetuses helps them keep one foot in power, then you better believe they don't have a problem with the idea of slurping down human-mouse hybrids made from fetuses (until a Democrat does it, of course).
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Oct 8, 2020 06:41
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The New Testament is riddled with conflicting theological doctrines and interpretations so one could argue that being two-faced about one’s faith is a very Christian thing to be.
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Oct 8, 2020 06:43
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uhhhhhhhhh
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Oct 8, 2020 06:44
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Phobophilia posted:Basically, the old way of making a monoclonal antibody is to inject the antigen (the coronavirus spike) into a mouse, then taking the B cells and fusing them with special tumor cells to form a hybridoma. You then isolate clones of these hybridomas, to screen for a clone that produces your specific monoclonal antibody. But all you're making are mouse antibodies, and putting a mouse antibody into a human will just make the human make anti-mouse antibodies, rendering your drug non-functional. Huh - yeah I did not know this, and that paper on how they did it is pretty interesting.
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Oct 8, 2020 07:04
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Grouchio posted:uhhhhhhhhh Starting to think the only donor Donnie and Co. have left is Grandfather Nurgle.
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Oct 8, 2020 08:26
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Grouchio posted:uhhhhhhhhh former vice presidents all bleed from the eye in modern debates. biden did it, now pence. contracts need to be paid, you see.
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Oct 8, 2020 12:23
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mediaphage posted:former vice presidents all bleed from the eye in modern debates. biden did it, now pence. contracts need to be paid, you see.  Dues need be repaid. anyway. this will happen https://twitter.com/Olivianuzzi/status/1314165624373944320 Dapper_Swindler fucked around with this message at 12:35 on Oct 8, 2020 |
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Oct 8, 2020 12:32
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oh yeah they probably use hek293 cells in there somewhere idk where hek293s are used freaking everywhere. they're so easy to transfect its a very selective form of outrage because all hek293s and their descendants originated from a single source, its not like you need to constantly refresh your supply with fresh abortions
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Oct 8, 2020 12:43
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gay picnic defence posted:Isn’t that the thing where they make human-mouse hybrid cells? The god botherers would lose their poo poo over that They only care when a Democrat does it.
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Oct 8, 2020 12:56
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Trump's already backed out of the virtual debate... low energy
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Oct 8, 2020 13:23
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Luv 2 get spit on by my Big Wet Infectious President at a circlejerk to own the libs A dumb Covid Rally is a Real Good use of your limited campaign funds lmao Trump on oxygen and steroids while his cults tells him how strong big daddy is
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Oct 8, 2020 14:05
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EngineerJoe posted:Trump's already backed out of the virtual debate... low energy
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Oct 8, 2020 14:49
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Sodomy Hussein posted:Brownback tried after Bush mentioned it in a state of the union, but the bill died. Republicans are afraid chimera means "the dog man from Invasion of the Body Snatchers" or "The Island of Dr. Moreau." Ah, I couldn't remember if they actually passed the law or not. I just remember how ridiculous it was that the GOP was more concerned about dog-cats than.... all the other poo poo that was going on
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Oct 8, 2020 15:19
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EngineerJoe posted:Trump's already backed out of the virtual debate... low energy He was absolutely going to take the first possible excuse to back out without losing face, no matter how flimsy. He's in no shape to debate.
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Oct 8, 2020 15:21
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Pants Donkey posted:It’s a losing proposition either way. He either looks like a petulant child or shows himself to be a hacking mess. Since the public already knows about the former it’s a better option, I guess. He said he'll do a rally, though, so we still get to see his hack-a-thon
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Oct 8, 2020 15:22
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HappyHippo posted:He was absolutely going to take the first possible excuse to back out without losing face, no matter how flimsy. He's in no shape to debate. He had also declared before this that he wouldn't debate virtually, presumably because then Sleepy Joe wouldn't be physically cowed by Trump's mighty presence in the room. But this fits his needs like a glove. He had his verbally-push-and-shove debate performance, so now he can rant about "Biden is SCARED of the virus that I beat handily" and "Biden wouldn't face me like a MAN again" and "Biden wants a virtual debate so people can feed him his lines on a teleprompter" while avoiding being under even virtual scrutiny for any length of time.
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Oct 8, 2020 15:50
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So did Trump go on another tweetstorm last night? Also what's the common consensus on where he is in the disease? I read something on Tuesday saying that if he was going to crash, it would be between today and Saturday, or something like that.
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Oct 8, 2020 17:32
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If you scroll back through this thread there are some different possible timelines put forward. But really no one fuckin knows because the White House refuses to release any sort of credible or consistent information beyond "HE WAS NEVER SICK BUT ALSO IF HE WAS HE'S CURED NOW AND BETTER THAN EVER! GET OWNED, LIBS" Honestly the most telling thing about his condition is that the biggest attention whore in human history can hardly show himself, even on video, during the home stretch of an election.
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Oct 8, 2020 17:41
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Gross Dude posted:He said he'll do a rally, though, so we still get to see his hack-a-thon I doubt he'll actually talk himself for very long. He might cap off a bunch of speakers with a prerecorded "I'm feeling great, don't be afraid of Covid, let's go get Sleepy Joe!" message, but his days of standing up and rambling for an hour to his captive audience are over for the foreseeable future.
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Oct 8, 2020 17:42
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Gross Dude posted:He said he'll do a rally, though, so we still get to see his hack-a-thon
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Oct 8, 2020 17:43
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