[canada] just another game of mad libs

The Something Awful Forums > Discussion > C-SPAM > [canada] just another game of mad libs

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Fashionable Jorts: Jan 18, 2010; Maybe if I'm busy it could keep me from you

xtal posted:

https://www.presidentschoice.ca/product/pc-sparkling-water-root-beer-flavour/21306197_C01

Woah that looks interesting. A no frills opened up near my place, I'll have to look for that.

# ? Apr 28, 2021 03:40

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# ? Jun 7, 2024 17:59

odiv: Jan 12, 2003

I've gotten them a few times and like them well enough. My wife would mix whatever "flavour" I got with OJ. :|

# ? Apr 28, 2021 04:08

Harold Stassen: Jan 24, 2016

I'm not a fan of the PC blue label sodas, they have a weird aftertaste to them despite being unsweetened. Safeway Compliments is a better soda as far as lemon, lemon/lime or lime soda goes

Only registered members can see post attachments!

# ? Apr 28, 2021 04:28

ZeeBoi: Jan 17, 2001

something I don�t think many have come to grips with yet is that COVID is here to stay and booster shots will probably be needed in the coming years

# ? Apr 28, 2021 06:00

Kazinsal: Dec 13, 2011

yeah I don't think we can make this go away forever without like, putting a three foot thick lead coffin around America

# ? Apr 28, 2021 06:08

Isizzlehorn: Feb 25, 2010

COMPAGNIE TOMMY posted:

I'm not a fan of the PC blue label sodas, they have a weird aftertaste to them despite being unsweetened. Safeway Compliments is a better soda as far as lemon, lemon/lime or lime soda goes

I just cut to getting vodka seltzer's.

Whatever you do, get low cal not the 0 calorie stuff. It's the equivalent of flavored farts.

# ? Apr 28, 2021 09:34

blatman: May 10, 2009; 14 inc dont mez

COMPAGNIE TOMMY posted:

I'm not a fan of the PC blue label sodas, they have a weird aftertaste to them despite being unsweetened. Safeway Compliments is a better soda as far as lemon, lemon/lime or lime soda goes

It's not blue label but there's a PC diet mango that's phenomenal

# ? Apr 28, 2021 12:10

ghosthorse: Dec 15, 2011; ...you forget so easily...

https://twitter.com/cityoftoronto/status/1387366889790361600?s=19

it surely isn't an extremely bad sign or anything that the city of Toronto effectively shrugged and gave up and handed off responsibility for this to some random twitter accout

# ? Apr 28, 2021 13:01

xtal: Jan 9, 2011; by Fluffdaddy

This country is an embarrassment

# ? Apr 28, 2021 13:10

Colonel Cancer: Sep 26, 2015; Tune into the fireplace channel, you absolute buffoon

Think of all the budget savings when you can just get a random internet weirdo to do your work for free

# ? Apr 28, 2021 13:18

Terror Sweat: Mar 15, 2009

Colonel Cancer posted:

Think of all the budget savings when you can just get a random internet weirdo to do your work for free

It works for forums. The only downside is the disproportionate number of child molesters as mods.

# ? Apr 28, 2021 13:33

flashy_mcflash: Feb 7, 2011

ghosthorse posted:

https://twitter.com/cityoftoronto/status/1387366889790361600?s=19

it surely isn't an extremely bad sign or anything that the city of Toronto effectively shrugged and gave up and handed off responsibility for this to some random twitter accout

Hey now!

They have a discord too

# ? Apr 28, 2021 13:39

Rutibex: Sep 9, 2001; by Fluffdaddy

xtal posted:

This country is an embarrassment

its not really a country just a resource extraction company

# ? Apr 28, 2021 14:09

Albino Squirrel: Apr 25, 2003; Miosis more like meiosis

ZeeBoi posted:

something I don�t think many have come to grips with yet is that COVID is here to stay and booster shots will probably be needed in the coming years

I don't give a poo poo if I have to get a booster shot every six months if it means I can travel and leave my garbage province.

Theoretically, since all the vaccines are intended to produce antibodies against the spike protein, they should all boost each other. So an AstraZeneca booster should provide substantial reactivation of the immune system primed by a Pfizer shot. There isn't evidence of this yet but I have no doubt it's being generated.

Also I would get the J&J or the AZ shot tomorrow if I hadn't already been vaccinated earlier in the year. My significant other still doesn't qualify for a shot and she would gladly take one from an unmarked white van parked out back of a 7-11.

# ? Apr 28, 2021 15:21

DariusLikewise: Oct 4, 2008; You wore that on Halloween?

linoleum floors posted:

Does anyone here know what brand of vaccines their kid has recieved?

my kids got a vaccine that they had to eat and they cried as soon as they tasted it so i can only assume it came from montanas

# ? Apr 28, 2021 15:29

DariusLikewise: Oct 4, 2008; You wore that on Halloween?

if brian pallisters pet doctor is to be believe i should get my shot in manitoba in the next 4 weeks

# ? Apr 28, 2021 15:29

EvilJoven: Mar 18, 2005; NOBODY,IN THE HISTORY OF EVER, HAS ASKED OR CARED WHAT CANADA THINKS. YOU ARE NOT A COUNTRY. YOUR MONEY HAS THE QUEEN OF ENGLAND ON IT. IF YOU DIG AROUND IN YOUR BACKYARD, NATIVE SKELETONS WOULD EXPLODE OUT OF YOUR LAWN LIKE THE END OF POLTERGEIST. CANADA IS SO POLITE, EH?; Fun Shoe

If Brian Pallister's pet doctor can be believed there's an invisible forcefield that prevents covid from spreading in any situation that funnels more money to the wealthy.

I get my shot on Monday at least.

# ? Apr 28, 2021 16:39

Another Bill: Sep 27, 2018; I stumbled ass-backwards into a comfortable, easy life for reasons beyond my comprehension and now I think I'm better than you for it.

Albino Squirrel posted:

Theoretically, since all the vaccines are intended to produce antibodies against the spike protein, they should all boost each other. So an AstraZeneca booster should provide substantial reactivation of the immune system primed by a Pfizer shot. There isn't evidence of this yet but I have no doubt it's being generated.

Studies are underway and Norway is apparently doing it already. I'm not a science guy but I think it will work out too from everything I've read.

https://twitter.com/PKBurian/status/1385940025532157955

# ? Apr 28, 2021 16:43

crispyseaweed: Sep 21, 2008

Ah yes, the Arnold Palmer

# ? Apr 28, 2021 16:46

Harold Stassen: Jan 24, 2016

If the shots are mixed and matched or otherwise not given as prescribed then the vaccination drive itself becomes just another theatrical safety aspect of the pandemic, since it's not guaranteeing any* real safety and in fact likely doing the opposite

*oh sorry maybe like 50% with one as opposed to 95% with both given properly, which is basically wholly vs half effective, not some quibbling percentages

Harold Stassen has issued a correction as of 17:35 on Apr 28, 2021

# ? Apr 28, 2021 17:32

bvj191jgl7bBsqF5m: Apr 16, 2017; IÍÌÌ° ÍÌ¯ÌÌ«Ì¹Ì¯Ì¤AÒmÍÌºÌ© ÍÌ¬AÌ¡Ì®ÌÌ ÍÍÌ±Ì« KÌ¶eÍgÍ.ÌÌ»Ì±ÌªÍÌ¹Ì

infernal machines posted:

is anything approved for under 18?

DMing moderators

# ? Apr 28, 2021 17:40

Another Bill: Sep 27, 2018; I stumbled ass-backwards into a comfortable, easy life for reasons beyond my comprehension and now I think I'm better than you for it.

COMPAGNIE TOMMY posted:

If the shots are mixed and matched or otherwise not given as prescribed then the vaccination drive itself becomes just another theatrical safety aspect of the pandemic, since it's not guaranteeing any* real safety and in fact likely doing the opposite

*oh sorry maybe like 50% with one as opposed to 95% with both given properly, which is basically wholly vs half effective, not some quibbling percentages

Actually none of your assumptions are known, that's why they're doing the studies?

# ? Apr 28, 2021 17:51

infernal machines: Oct 11, 2012; we monitor many frequencies. we listen always. came a voice, out of the babel of tongues, speaking to us. it played us a mighty dub.

bvj191jgl7bBsqF5m posted:

DMing moderators

i guess if anyone would know, it'd be them

# ? Apr 28, 2021 17:53

Harold Stassen: Jan 24, 2016

Another Bill posted:

Actually none of your assumptions are known, that's why they're doing the studies?

From the standpoint of risk management (as opposed to champing at the bit to get people spending again) anything unknown is a reason to be cautious as opposed to validating incautious behavior, until the actual risk is known. Not understanding the extant risks and taking that as "all is permitted" is what children do

# ? Apr 28, 2021 18:09

Another Bill: Sep 27, 2018; I stumbled ass-backwards into a comfortable, easy life for reasons beyond my comprehension and now I think I'm better than you for it.

COMPAGNIE TOMMY posted:

From the standpoint of risk management (as opposed to champing at the bit to get people spending again) anything unknown is a reason to be cautious as opposed to validating incautious behavior, until the actual risk is known. Not understanding the extant risks and taking that as "all is permitted" is what children do

That's an awful lot of big words to say nothing

# ? Apr 28, 2021 18:16

Slotducks: Oct 16, 2008; Nobody puts Phil in a corner.

Risk Management is when people make fun spreadsheets to justify doing something incredibly risky and acknowledging it's risky as all hell and blindly moving forward not the inverse lmao

# ? Apr 28, 2021 18:32

Juul-Whip: Mar 10, 2008

it's not polyjuice potion, there's nothing special about doing it after 3 weeks vs 3 months. That was just the timing they went with in the very fast trial studies to get the vaccines on the market. A recent study out of the UK actually indicates its probably better to wait 3 months~ for the second AstraZenica dose rather than rush it

# ? Apr 28, 2021 18:38

prom candy: Dec 16, 2005; Only I may dance

after i get my first shot i'm gonna edge my second shot until i can't fuckin stand it and then i'll get a huge explosive immune response

# ? Apr 28, 2021 18:57

Fried Watermelon: Dec 29, 2008

To get the second dose the government is forcing us to buy $100 Tim Horton giftcards

# ? Apr 28, 2021 19:02

pokeyman: Nov 26, 2006; That elephant ate my entire platoon.

COMPAGNIE TOMMY posted:

From the standpoint of risk management (as opposed to champing at the bit to get people spending again) anything unknown is a reason to be cautious as opposed to validating incautious behavior, until the actual risk is known. Not understanding the extant risks and taking that as "all is permitted" is what children do

we had this exact discussion in this thread like two weeks ago. post some evidence or give it up

# ? Apr 28, 2021 19:09

odiv: Jan 12, 2003

Fried Watermelon posted:

To get the second dose the government is forcing us to buy $100 Tim Horton giftcards

Ne s�applique pas aux r�sidents du Qu�bec.

# ? Apr 28, 2021 19:10

BonerKid: Jan 3, 2002; Chill

BonerKid has issued a correction as of 21:13 on Oct 29, 2022

# ? Apr 28, 2021 19:11

flashy_mcflash: Feb 7, 2011

I prefer my breakfast sandwiches to remain uncracked, thank you.

# ? Apr 28, 2021 19:51

Harold Stassen: Jan 24, 2016

pokeyman posted:

we had this exact discussion in this thread like two weeks ago. post some evidence or give it up

That's why they're doing the study (but first we're doing it live and not recording the results in any serious way)

# ? Apr 28, 2021 22:07

pokeyman: Nov 26, 2006; That elephant ate my entire platoon.

COMPAGNIE TOMMY posted:

That's why they're doing the study (but first we're doing it live and not recording the results in any serious way)

I didn't see anyone mixing vaccines live? I thought the doing it live part was delaying a second dose to more thoroughly spread the first dose

# ? Apr 28, 2021 22:25

Fashionable Jorts: Jan 18, 2010; Maybe if I'm busy it could keep me from you

Kazinsal posted:

yeah I don't think we can make this go away forever without like, putting a three foot thick lead coffin around America

Don't forget Alberta. I think we're world leaders right now in "How to gently caress up year 2 of this pandemic"

# ? Apr 28, 2021 23:25

Another Bill: Sep 27, 2018; I stumbled ass-backwards into a comfortable, easy life for reasons beyond my comprehension and now I think I'm better than you for it.

quote:

Can I get a different type of vaccine for my second dose?

PAUL TAYLOR
SPECIAL TO THE GLOBE AND MAIL
PUBLISHED 3 HOURS AGO
UPDATED APRIL 28, 2021

The question: I followed the advice of public-health officials who urged us to take the first available COVID-19 vaccine. For me, it turned out to be the AstraZeneca shot. Will I be able to get another type of vaccine for my second dose?

The answer: You�re not the only person wondering whether the vaccines can be used interchangeably.

In fact, researchers in Britain have launched a study to determine if it�s safe and effective to mix different vaccines that guard against SARS-CoV-2, the novel coronavirus that causes COVID-19.

�It�s a hugely important question that is being addressed by this study,� says Rob Kozak, a scientist and clinical microbiologist at Sunnybrook Health Sciences Centre in Toronto.

�It could potentially help alleviate a lot of our supply problems,� he adds.

In Canada, the vaccination rollout has been plagued by availability issues. The flow of vaccines from some companies has dwindled to a trickle while others have provided more and more doses.

To even out the supply, Dr. Kozak says it would be convenient if two different vaccines could be used for the same person. Most of the COVID-19 vaccines require a double injection � a primer dose followed by a booster to amplify and extend the immune response.

The British study began in February with the recruitment of about 800 volunteers using the AstraZeneca and Pfizer shots. Some got two doses of the same vaccine � an immunizing strategy known as a homologous prime-boost. Others received one dose of each vaccine � or a heterologous prime-boost.

Blood samples from the volunteers are being analyzed for the presence of antibodies and others cellular indicators that show how well the body�s immune system is prepared to fight the virus.

Aside from potentially alleviating supply issues, the study might also reveal that using different shots may actually produce better overall protection than relying on a single type of vaccine, says Zhou Xing, a professor at the McMaster Immunology Research Centre in Hamilton.

He notes that all COVID-19 vaccines train the immune system to be on the lookout for spike proteins, the knobby protrusions on the surface of the coronavirus. But the various vaccines work in slightly different ways. That means they have different effects on the immune system.

For instance, Pfizer and Moderna, which are based on a relatively new vaccine technology using messenger RNA, are extremely effective at stimulating the production of antibodies � the first line of defence against a foreign invader. The antibodies will normally latch onto a virus to prevent it from entering and infecting a cell.

On the other hand, AstraZeneca appears to have an enhanced capacity for producing T-Cells, which provide a critical back-up defence if the virus eludes the antibodies. A �killer� T-cell can identify an infected cell and destroy it, he explains.

Dr. Xing thinks there may be a significant advantage in giving people two types of vaccine. Essentially, they might acquire the best protection offered by each one, filling in any immunological gaps. �I�m a big believer in mixing vaccines,� he says.

But an even more urgent reason to try mixing vaccines is the worrisome emergence of new viral variants, says Alan Bernstein, president of CIFAR, a Canadian-based global research organization.

Not only are certain variants deadlier and more contagious than the original SARS-CoV-2, but some of them may be able to evade, at least to some degree, the protection provided by vaccination.

By combining vaccines, �it might help broaden the response so the immune system can better deal with the variants,� says Dr. Bernstein, who is also a member of the federal COVID-19 Vaccine Task Force.

He says the initial results from the British study are expected to be released in the next few weeks. If they show that mixing shots is better than boosting with the same vaccine, �I would hope we would go with the heterologous prime-boost strategy as soon as possible.�

In Quebec, public-health officials are already considering giving the Pfizer shot to some seniors who were originally inoculated with the Moderna vaccine, which is now in short supply.

Dr. Bernstein says mixing shots might also help overcome vaccine hesitancy. He points out that a lot of people received a first dose of AstraZeneca before it was linked to extremely rare cases of blood clots. Some individuals may now be reluctant to get their second dose. If they are able to receive another type of vaccine, they may be more willing to roll up their sleeves for an injection, he says.

�Flexibility is important,� says Dr. Bernstein. �The sooner we give everyone in Canada two doses of these vaccines, the better we will all be protected.�

Seems like a timely article for this thread.

# ? Apr 28, 2021 23:45

Kazinsal: Dec 13, 2011

Fashionable Jorts posted:

Don't forget Alberta. I think we're world leaders right now in "How to gently caress up year 2 of this pandemic"

I thought albertans didn't identify as canadian

# ? Apr 28, 2021 23:55

ghosthorse: Dec 15, 2011; ...you forget so easily...

Kazinsal posted:

I thought albertans didn't identify as canadian

when someone online says they're Canadian assume they're only really talking about their specific preferred province/territory/city. when someone online says they're a "proud Canadian" assume they're racist

e: it's us, the land of lovely contrasts

# ? Apr 29, 2021 00:26

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# ? Jun 7, 2024 17:59

Do it ironically: Jul 13, 2010; by Pragmatica

There are so many loving idiots in kelowna it's depressing, just lovely mouth breathing anti maskers and anti vaxxers harassing workers. I had an anti masker/vaxxer recently, which I didn't know at the time till they started spouting off but they were telling me that weed cures cancer, and they were serious, this is a dude my age with 3 kids and a decent education, where do these people get this poo poo

# ? Apr 29, 2021 01:07

The Something Awful Forums > Discussion > C-SPAM > [canada] just another game of mad libs

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