Register a SA Forums Account here!
JOINING THE SA FORUMS WILL REMOVE THIS BIG AD, THE ANNOYING UNDERLINED ADS, AND STUPID INTERSTITIAL ADS!!!

You can: log in, read the tech support FAQ, or request your lost password. This dumb message (and those ads) will appear on every screen until you register! Get rid of this crap by registering your own SA Forums Account and joining roughly 150,000 Goons, for the one-time price of $9.95! We charge money because it costs us money per month for bills, and since we don't believe in showing ads to our users, we try to make the money back through forum registrations.
 
  • Post
  • Reply
MarcusSA
Sep 23, 2007

Ichabod Sexbeast posted:

With sufficient global vaccination, is full elimination on the table?

As I understand it (which may not be very much at all) it needs a reservoir to hang out it, and it's not a disease that can lay dormant/latent long-term. Schools, children, and the unvaccinated are obvious candidates, but is there a minimum reservoir size it needs (assuming we don't get some bone-melting epsilon variant that can spread through the internet)?

I’m gonna have to say no since the vaccines aren’t 100% so transmission will still happen between unvaccinated people (probably kids mostly). It’s going to be like the flu except with this you probably have to get a booster every year for it.

Adbot
ADBOT LOVES YOU

Sjs00
Jun 29, 2013

Yeah Baby Yeah !

Mozi posted:

No, it's entirely appropriate to take stock and appreciate how some things are actually going well and worked out in our favor.

If you think it's useless to reflect on how not everything is the absolute worst, then you need to change your context and try to change something about your life. Reflexive internet cynicism is boring, tired and poisonous.

you I and everyone reading this has been a doomscroller long before smartphones
also, let's read the posts shall we? I intoned to thread poster Mozi (you) that if vaccines were worse, yes, things would be going worse than they are. Its not even valuable to think about a worse handle on sars covid 19 than what we have here, in regards to the possibilities of loving up Project Lightspeed . The vaccines and their effectiveness is one of the few good things we have seen. I think we spoke past eachother

e feel free to continue to lecture on about internet cynicism here in the LIGMA BALLS VARIANT gbs thread

Sjs00 fucked around with this message at 19:32 on Jul 1, 2021

Mr Luxury Yacht
Apr 16, 2012


MarcusSA posted:

I’m gonna have to say no since the vaccines aren’t 100% so transmission will still happen between unvaccinated people (probably kids mostly). It’s going to be like the flu except with this you probably have to get a booster every year for it.

I think the bigger problem is sufficient global vaccination to eliminate COVID-19 isn't going to happen any time soon. If everyone in the world was vaccinated with an 80-95% effective vaccine then yeah you could probably eliminate it but that won't be possible given 1. We can't even convince everyone to get vaccinated in countries where the vaccine is essentially unlimited and 2. The majority of the planet isn't in those countries and can't even get the vaccine at all right now (and it'll be quite a while before they can).

Riptor
Apr 13, 2003

here's to feelin' good all the time

MarcusSA posted:

It’s going to be like the flu except with this you probably have to get a booster every year for it.

I think the jury's still out on if we'll need annual boosters for covid, but what do you mean like the flu but you'll have to get annual boosters? That's what the flu is like now

learnincurve
May 15, 2014

Smoosh

Charliegrs posted:

Are there any stats on how well the J&J vaccine works against the Delta varient?

The Data on delta is coming out of the U.K. and unfortunately we won’t have any information as the only J&J use that has been planned is that doctors will be authorised to use it after the main rollout in cases where they don’t think the person will come back for a second shot.

MarcusSA
Sep 23, 2007

Riptor posted:

I think the jury's still out on if we'll need annual boosters for covid, but what do you mean like the flu but you'll have to get annual boosters? That's what the flu is like now

Yes but you don’t have to get a flu shot every year.

Yeah the jury is still out on the boosters but if it shows you need it people will definitely have to get it and can’t just slag it off like the flu shot.

Also the flu shot is a little different since they use their best guess as to which variant is going to be predominant for a given year and sometimes they wiff it lol

learnincurve
May 15, 2014

Smoosh

Riptor posted:

I think the jury's still out on if we'll need annual boosters for covid, but what do you mean like the flu but you'll have to get annual boosters? That's what the flu is like now

We are rolling out boosters in September in the U.K. with flu shots to those eligible and then the plan is to have AZ start tailoring boosters to the current active variants from 2022.

Edit: in the U.K. the over 50s and vulnerable get flu shots every year.

MarcusSA
Sep 23, 2007

learnincurve posted:


Edit: in the U.K. the over 50s and vulnerable get flu shots every year.

I’d be very curious what % actually got those flu shots.

AFAIK the flu shot numbers here in the us are always comically low.

learnincurve
May 15, 2014

Smoosh
Given that our covid uptake is over 95% whenever an age group becomes available it’s shouldn’t be a massive shock that we are world beating at flu jabs as well

https://www.gov.uk/government/news/flu-vaccine-uptake-among-over-65s-highest-on-record

My wild theory is it’s to do with post office queues, you got millions and millions of old people who were used to queueing for their money and having a chat each week, now that’s changed they must see the vaccine queue line as a way to catch up on the gossip.

freebooter
Jul 7, 2009

MarcusSA posted:

Yes but you don’t have to get a flu shot every year.

Uh, you don't have to do anything, but you can and should get a flu shot every year.

SulfurMonoxideCute
Feb 9, 2008

I was under direct orders not to die
🐵❌💀

Alberta lifted all Covid restrictions today, with exception for municipal bylaw and business choice. My husband's work is currently stating all staff have to keep wearing masks for another month but customers don't have to. Calgary still has it's mask mandate for public buildings in place for at least 5 more days.

Detheros
Apr 11, 2010

I want to die.



Charliegrs posted:

Are there any stats on how well the J&J vaccine works against the Delta varient?

Some super early reports are that it works as well as the j&j vaccine works for others, so slightly less than moderna and the like, but still good coverage.

Lolie
Jun 4, 2010

AUSGBS Thread Mum
We haven't had a death in a locally acquired case so far this year, but we now have a few cases in ICU.

Time and time again this virus reminds us that we can go months without any locally acquired cases, only to have things go pear shaped when we get complacent.

Inexcusable errors have been made this time around, and there needs to be a reckoning.

Helith
Nov 5, 2009

Basket of Adorables


Lolie posted:

Inexcusable errors have been made this time around, and there needs to be a reckoning.

I'm having a wonderful daydream of your avatar going on a rampage across Australia now :allears:

Lolie
Jun 4, 2010

AUSGBS Thread Mum

Helith posted:

I'm having a wonderful daydream of your avatar going on a rampage across Australia now :allears:

lol

ThatGirlAtThatShow
Nov 4, 2013

learnincurve posted:


It’s not a awesome thing at all when you think how much pain and suffering could have been avoided in the past if people had just backed the gently caress off and not crowded people in wheelchairs

My daughter died from leukemia but the thing that weakened her was catching the chicken pox from neighbor kids, who I tried to keep out of our yard, but everybody (including the cops) told me "You can't stop kids, she'll be fine."

Which is why, frankly, I'm a LOT salty about being told I should care about other people and mask all the time. Nobody cared about mine, why should I care about them?

Oh, that's right. Cos we were poor.

goddamnedtwisto
Dec 31, 2004

If you ask me about the mole people in the London Underground, I WILL be forced to kill you
Fun Shoe

learnincurve posted:

AZ don’t think they can get the new Delta mutation booster vaccine ready for flu season, so we are going to be doing the mixed vaccine route with with an extra shot of Moderna, Pfizer, or this new novavax this winter.

As there seems to be (admittedly very, very limited) evidence that mixing and matching AZ and mRNA gives efficacy above two jabs of either this might be another case of the UK falling arse-backwards into the best possible outcome.

(I have to admit part of me has been very tempted to pretend not to have an NHS number and just waltzing through one of the pop-up Pfizer sites)

goddamnedtwisto
Dec 31, 2004

If you ask me about the mole people in the London Underground, I WILL be forced to kill you
Fun Shoe

MarcusSA posted:

I’m gonna have to say no since the vaccines aren’t 100% so transmission will still happen between unvaccinated people (probably kids mostly). It’s going to be like the flu except with this you probably have to get a booster every year for it.

We eliminated smallpox and (until the CIA hosed it all up) were extremely close to eliminating polio with vaccines with 60-70% efficacy. Current measles vaccines are also only around 80%, and measles is a *lot* more contagious than covid, and we still have it basically suppressed in the west even with terrible uptake.

You do not need 100% efficacy *or* 100% uptake, just sufficient of both to get the R0 under 1. We don't know exactly what the magic number is (and things are being muddied at the moment because we still don't know how much to worry about asymptomatic spread) but there is a number less than 100% where we can start the party.

Purgatory Glory
Feb 20, 2005
I always find it interesting that population density doesn't become much more relevant with this stuff. If Canada ignore vaccination altogether they are 37 million unvaxxed and screwed. If India has 37 million unvaxxed they they have a Vax rate of 97.5% and have beat the thing?

goddamnedtwisto
Dec 31, 2004

If you ask me about the mole people in the London Underground, I WILL be forced to kill you
Fun Shoe

Purgatory Glory posted:

I always find it interesting that population density doesn't become much more relevant with this stuff. If Canada ignore vaccination altogether they are 37 million unvaxxed and screwed. If India has 37 million unvaxxed they they have a Vax rate of 97.5% and have beat the thing?

That's not population density, that's just... population. And I think most times people talk about vaccine rollout they do tend to use percentages or per-100k or similar numbers rather than raw numbers, unless it's general willy-waving about speed of rollout.

Population density *is* often overlooked though when people are talking about spread and relative success of different measures. Darling of the anti-lockdown crowd Sweden is a very spread-out nation (25 people per square kilometre) which obviously means spread is much, much slower than in the UK (281/km2). Aha, they say, but Sweden is actually mostly empty, most people live in the cities - but the same is very much true of the UK, and those cities are also much less dense than UK ones. Stockholm has a population density that at first looks roughly comparable to London (4.8k/km2 compared to 5.7) but like a lot of European cities they cheat by not counting the outer suburbs - the comparable number for London (i.e. taking only the inner boroughs) is nearer 12k/km2.

Of course even this doesn't tell the whole story because once you get over a certain density (at least in not-poo poo cities) you have to throw in much higher rates of socialising out of the house and public transport use which also turbo-charge the spread.

Snowglobe of Doom
Mar 30, 2012

sucks to be right

goddamnedtwisto posted:

Darling of the anti-lockdown crowd Sweden is a very spread-out nation (25 people per square kilometre) which obviously means spread is much, much slower than in the UK (281/km2). Aha, they say, but Sweden is actually mostly empty, most people live in the cities - but the same is very much true of the UK, and those cities are also much less dense than UK ones. Stockholm has a population density that at first looks roughly comparable to London (4.8k/km2 compared to 5.7) but like a lot of European cities they cheat by not counting the outer suburbs - the comparable number for London (i.e. taking only the inner boroughs) is nearer 12k/km2.

It was really galling that Sweden's pandemic response was constantly being touted as an example of a successful alternative to everywhere else by Fox News and the UK tabloids because although their outcomes looked really good compared to the US and the UK they were always demonstrably worse than most of the countries surrounding them. Poland and Lithuania gave them a run for their money but Norway, Finland and Denmark always had much much better outcomes.




Sweden's pandemic response was always bad

Zero One
Dec 30, 2004

HAIL TO THE VICTORS!

Charliegrs posted:

Are there any stats on how well the J&J vaccine works against the Delta varient?

https://twitter.com/nytimes/status/1410893773081649153?s=21

Roman
Aug 8, 2002

Zero One posted:

"The Johnson & Johnson coronavirus vaccine is effective against the highly contagious Delta variant, even eight months after inoculation, the company reported on Thursday."
There is also this as a counterpoint, BUT it is anecdotal:
https://losangeles.cbslocal.com/2021/06/29/johnson-johnson-delta-variant/

“The ones that are vaccinated, though, that end up testing positive, 9 times out of 10 are in patients that have received the J&J vaccine."

But maybe there's just lots of J&J in LA, so correlation doesn't equal causation and all that. (Pfizer/Moderna are/were WAY more available here in NY, I couldn't find J&J sites at all a few months ago)

I got Pfizer but if I had got J&J I would go get a booster just to make sure.

Zero One
Dec 30, 2004

HAIL TO THE VICTORS!

Roman posted:

There is also this as a counterpoint, BUT it is anecdotal:
https://losangeles.cbslocal.com/2021/06/29/johnson-johnson-delta-variant/

“The ones that are vaccinated, though, that end up testing positive, 9 times out of 10 are in patients that have received the J&J vaccine."

But maybe there's just lots of J&J in LA, so correlation doesn't equal causation and all that. (Pfizer/Moderna are/were WAY more available here in NY, I couldn't find J&J sites at all a few months ago)

I got Pfizer but if I had got J&J I would go get a booster just to make sure.

I ended up doing that last weekend (got Moderna). I am in the JnJ trial and got the vaccine in November so I've been worried about both JnJ's effectiveness and how long it lasts.

I talked to the study people and they said it was ok to get another vaccine they just wanted to know so they can add it to my file. So I did.

Snowglobe of Doom
Mar 30, 2012

sucks to be right

Zero One posted:

quote:

The Johnson & Johnson coronavirus vaccine is effective against the highly contagious Delta variant, even eight months after inoculation, the company reported on Thursday.

I'm going to guess that "is effective" isn't the kind of stats that Charliegrs was asking for. :v:

The article is behind a pay wall, do they give any actual efficacy numbers?

Zero One
Dec 30, 2004

HAIL TO THE VICTORS!

Snowglobe of Doom posted:

I'm going to guess that "is effective" isn't the kind of stats that Charliegrs was asking for. :v:

The article is behind a pay wall, do they give any actual efficacy numbers?

Here is the press release https://www.prnewswire.com/news-rel...-301324791.html

Roman
Aug 8, 2002

Snowglobe of Doom posted:

I'm going to guess that "is effective" isn't the kind of stats that Charliegrs was asking for. :v:
The article is behind a pay wall, do they give any actual efficacy numbers?

quote:

But other experts said the clinical trials should have made it apparent that the efficacy of the J.&J. vaccine was lower than that of the mRNA vaccines. “Seventy-two percent is of course lower than 95 or 94 percent,” said Florian Krammer, an immunologist at the Icahn School of Medicine at Mount Sinai in New York.

Part of the difficulty in comparing the vaccines is that they were all tested individually and with different measures of success. The Pfizer-BioNTech and Moderna trials were designed to tally symptomatic infections, while the J.&J. trial assessed the vaccine’s prevention of moderate to severe infections.

Scarodactyl
Oct 22, 2015


Pfizer trial keeps delaying my third dose for one reason or another. Still hoping for next week or the week after.

Snowglobe of Doom
Mar 30, 2012

sucks to be right

Roman posted:

quote:

But other experts said the clinical trials should have made it apparent that the efficacy of the J.&J. vaccine was lower than that of the mRNA vaccines. “Seventy-two percent is of course lower than 95 or 94 percent,” said Florian Krammer, an immunologist at the Icahn School of Medicine at Mount Sinai in New York.

Part of the difficulty in comparing the vaccines is that they were all tested individually and with different measures of success. The Pfizer-BioNTech and Moderna trials were designed to tally symptomatic infections, while the J.&J. trial assessed the vaccine’s prevention of moderate to severe infections.

So it shows 72% efficacy against moderate/severe Delta infection, there's no word on its efficacy against symptomatic infections in general or asymptomatic infections, and the press release only says that it "demonstrated protection" against death.

When Charliegrs kicked off this whole conversation by asking "Are there any stats on how well the J&J vaccine works against the Delta varient?" someone could have just said "No, hardly any" and saved us all a lot of time. :v:

learnincurve
May 15, 2014

Smoosh
I have a link to the latest J&J study done by themselves if anyone can understand it

https://www.biorxiv.org/content/10.1101/2021.07.01.450707v1

Fluffy Bunnies
Jan 10, 2009

17k+ new cases today in the US up from what, 8-9k the past week or so?

I'm never going to see my spouse again :lol:

Tiny Timbs
Sep 6, 2008

why not

LanceHunter
Nov 12, 2016

Beautiful People Club


Fluffy Bunnies posted:

17k+ new cases today in the US up from what, 8-9k the past week or so?

I'm never going to see my spouse again :lol:

16,571 cases (according to the NYTimes tally), and Fridays have been consistently showing the highest case counts for a while now (last Friday was 14,956). The 7-day average is up about 5% at 12,809, but that is after weeks of having 10%-30% drops. Also, this time last year was a little over a week into the summer surge, where cases hit 49k and were rising rapidly. A lot of folks in the warmer parts of the country are now, just like they were then, gathered in indoor spaces with recirculating air. This time, though, the vaccine is doing its job.

Fluffy Bunnies
Jan 10, 2009

LanceHunter posted:

This time, though, the vaccine is doing its job.

88% of it anyhow

of 47% of 12+ Americans.

E: I wish we could vaporize it and just blow it into every restaurant :smith: because it's the only way we're getting anywhere close to vaccinated in this area.

Roman
Aug 8, 2002

We need to find a way to put vaccines into high fructose corn syrup

The US would be vaccinated in less than 24 hours just from those $1 Arizona Ice Teas alone

Lolie
Jun 4, 2010

AUSGBS Thread Mum

Roman posted:

We need to find a way to put vaccines into high fructose corn syrup

The US would be vaccinated in less than 24 hours just from those $1 Arizona Ice Teas alone

I was immunised against polio with Sabin, which is an oral vaccine. Three drops of vaccine on a sugar cube was how it was administered.

fappenmeister
Nov 19, 2004

My hand wields the might

Got my second Pfizer dose in Melbourne today.

01110111 01100101 01101100 01100011 01101111 01101101 01100101 00100000 01110100 01101111 00100000 01110011 01101011 01111001 01101110 01100101 01110100

So when do the side effects happen, and can I have a seltzer first?

Thought it was going to feel way more relieving than this. I just feel sad that our rollout is garbage.

Ugly In The Morning
Jul 1, 2010
Pillbug

fappenmeister posted:

Got my second Pfizer dose in Melbourne today.

01110111 01100101 01101100 01100011 01101111 01101101 01100101 00100000 01110100 01101111 00100000 01110011 01101011 01111001 01101110 01100101 01110100

So when do the side effects happen, and can I have a seltzer first?

Thought it was going to feel way more relieving than this. I just feel sad that our rollout is garbage.

Maybe it wasn’t as relieving because AU has been relatively able to stop it from getting there. I had the rona BAD early on and even with the stuff showing natural immunity was pretty decent getting my shot was a giant load off.

fappenmeister
Nov 19, 2004

My hand wields the might

Ugly In The Morning posted:

Maybe it wasn’t as relieving because AU has been relatively able to stop it from getting there. I had the rona BAD early on and even with the stuff showing natural immunity was pretty decent getting my shot was a giant load off.

Yes, this actually is one of the other reasons too, you're able to elucidate it better than I could.

I can't imagine what it was like for you and the country, though.

Adbot
ADBOT LOVES YOU

Philthy
Jan 28, 2003

Pillbug
So have they said that we will likely want boosters after x amount of time, and are they prepping for that right now so it wont be a hassle? We can just go in anytime and be "yo, i want my booster" and they jab ya again and yer done?

  • 1
  • 2
  • 3
  • 4
  • 5
  • Post
  • Reply