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Bad Purchase posted:a lot of people will threaten to quit, but these are the same cowards scared of vaccines that have been taken by a billion people now. they'll probably be even more scared of losing their job and fall in line after a public tantrum. LOL, I hadn't thought of the fact that if someone is still employed it is going to be a scarlet letter to the most rabid anti-reality fuckwits out there. My state has already said that refusing to get vaccinated will not qualify for unemployment, so unless they have an actual medical exemption they are pretty hosed here.
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Sep 10, 2021 00:54
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Fallom posted:Oh no not vaccinations and masks I'm glad to see the authorities managing expectations here. It's something which doesn't seem to have happened in the US and the UK and I think that acknowledging there's been a fundamental, unanticipated shift in how society functions is important.
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Sep 10, 2021 00:58
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Biden has a spine if steel it turns out
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Sep 10, 2021 01:24
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Speaking of COVID, I'm glad to see Florida got it all under control before NFL season: https://twitter.com/FortheBaycc/status/1436121571249344512 Already being referred to as "The COVID Bowl". No vaccine proof requirement, no masks, no social distancing. Just looking at that makes me feel anxious
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Sep 10, 2021 01:28
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I've seen a lot of complaints about religious exemptions, but I'm much more worried about companies just lazily doing stuff like not documenting vaccination at all and just having employees check a box on form or something.
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Sep 10, 2021 01:29
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Holy moly this is WAY more than I expected from the Biden administration , this is greatTheBuilder posted:This is going to be a riot. They'll probably storm a state house or two but that's just business as usual these days wilderthanmild posted:Also all of those points on the plan are good except for one sneaky guy He's been beating that drum since 2020, it's pretty much a cornerstone of his presidency and I doubt he's going to back down from it now whatever happens https://twitter.com/joebiden/status/1341493715811127298
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Sep 10, 2021 01:38
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Lolie posted:Do you think that 2022 "normal" will be like 2019 normal? Different but WAY better than right the gently caress now
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Sep 10, 2021 01:50
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Mr Ice Cream Glove posted:Speechless The dude saying the prayer reminds me of the heavy kid with a lisp in Heaven Help Us. https://www.youtube.com/watch?v=dIrtQAibsNA
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Sep 10, 2021 01:52
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Fallom posted:Oh no not vaccinations and masks you would be shocked at how many people think this is a case of either-or and will throw a screaming tantrum like a four year old if you advise them otherwise
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Sep 10, 2021 01:54
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Gimme all the boosters https://twitter.com/moderna_tx/status/1435978825377136641
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Sep 10, 2021 03:11
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Snowglobe of Doom posted:Gimme all the boosters I have a feeling we unlocked something amazing with mRNA tech.
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Sep 10, 2021 03:16
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Zil posted:I have a feeling we unlocked something amazing with mRNA tech. We did, although the mRNA immunotherapies for cancer are the show-stoppers.
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Sep 10, 2021 03:24
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how did mRNA tech fly under the radar? I seem to recall something called "bacteria phages" was suppose to be one of the future supa medical science thing, and it was a pop science topic of the week/month, but then the hype died and it went into the slow grind/small incremental advancement part of the science cycle.
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Sep 10, 2021 03:38
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CaptainSarcastic posted:LOL, I hadn't thought of the fact that if someone is still employed it is going to be a scarlet letter to the most rabid anti-reality fuckwits out there. Yeah, I love all this handwringing over how enforcement is going to work like employers wouldn't love the opportunity to quickly identify and fire with clear cause their most dumbfuck employees. "Sorry Bob, but you have to go. Yep, I know, I'm sad too, but my hands are tied, OSHA." 
Three Olives fucked around with this message at 03:44 on Sep 10, 2021 |
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Sep 10, 2021 03:40
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PhazonLink posted:how did mRNA tech fly under the radar? Bacteriophages, which are viruses that attack bacteria, are still around and used in some treatments. As you say, progress is incremental. (IANAD)
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Sep 10, 2021 03:46
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PhazonLink posted:how did mRNA tech fly under the radar? The mainstream never gave a poo poo about viruses (until they became a problem, forcing people away from Applebee's) The closest modern epidemic (AIDS) only affected THE GAYS AND POORS, so 
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Sep 10, 2021 03:53
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Sep 10, 2021 04:04
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Comfy Fleece Sweater posted:The mainstream never gave a poo poo about viruses (until they became a problem, forcing people away from Applebee's) And then they called us disgusting diseased whores (including all of us not living with HIV), said we deserved to die from AIDS for not wearing a condom and tried to make exposing someone to HIV a felony even after we understood that if you were living with HIV that was adherent to medication it was impossible to transmit and you used a condom and the person you had sex with didn't seroconvert. BUT MASKS AND MY FREEDOMS 
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Sep 10, 2021 04:05
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I think I got dumber reading that. My brain hurts
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Sep 10, 2021 04:05
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Zil posted:I think I got dumber reading that. My brain hurts Fox News is an incredible web site
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Sep 10, 2021 04:07
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Except modern microwaves now include a metal center rack. 
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Sep 10, 2021 04:09
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Why does that rock monster need a microwave to heat up metal to eat? Just have Enrique heat it up.
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Sep 10, 2021 04:09
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Really makes u think
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Sep 10, 2021 04:13
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i just noticed the nazi username too god dang
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Sep 10, 2021 04:15
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PhazonLink posted:how did mRNA tech fly under the radar? It wasn't until about 10 years ago that they figured out how to keep it somewhat shelf stable (by suspending it in fat), so it wasn't scaleable.
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Sep 10, 2021 04:19
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yeah mRNA wasn’t at all under the radar. they’ve been working on it for the past two decades. the tricky part was finding some mechanism to deliver the mRNA into your cells before your immune system could tear it to shreds. they were starting to use it in cancer treatments and other weird diseases caused by protein deficiencies when covid hit us we were really REALLY lucky this tech was ready to rock n roll
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Sep 10, 2021 04:40
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No surprises here https://twitter.com/GregAbbott_TX/status/1436104824660049921
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Sep 10, 2021 06:48
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Snowglobe of Doom posted:No surprises here "You can't work here during a pandemic that's overloading all the hospitals if you aren't vaccinated from the disease" "Quit power grabbing! "*cough*
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Sep 10, 2021 07:02
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Snowglobe of Doom posted:No surprises here https://www.youtube.com/watch?v=embMAtagQiU  This is a really weird issue for conservative politicians to choose as a hill they want to climb, the vaccine is not only extremely popular, the people that have had it are starting to get really angry at the people that haven't gotten it and view them as dangerous idiots. Three Olives fucked around with this message at 07:10 on Sep 10, 2021 |
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Sep 10, 2021 07:02
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Purgatory Glory posted:"You can't work here during a pandemic that's overloading all the hospitals if you aren't vaccinated from the disease" Ill be worried if they start tell chuds to avoid death. Till then this is just more of the lords work.
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Sep 10, 2021 07:12
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Three Olives posted:https://www.youtube.com/watch?v=embMAtagQiU Abbot is being primaried from the right. His only choice is to appeal to the crazies who vote in the R primary.
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Sep 10, 2021 07:25
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Update boquiabierta posted:Ughhhh how are people dealing with large events where there may be unvaccinated people along with children? We've been planning to go to my brother-in-law's wedding in October, but for some reason didn't think to check their Covid protocols until just now. Turns out they don't have any. Well, they "expect unvaccinated (and vaccinated) people to abide by US guidelines" but they're not making that explicit in any way. Their wedding website has absolutely nothing about Covid, they're not asking for vaccination status or proof of vax or tests, and they're not asking unvaxxed people to mask. It's going to be 150 people, jfc, and my brother-in-law thinks maybe there are some people on his in-laws' side who "lean right" and might not be vaccinated. But they won't ask them or do anything to try to make it safer for the 10-15 kids they're expecting, including our 18-month-old. Welp, the wedding's off now. My BIL and his wife wound up asking everyone to be vaccinated and to mask at the wedding except when eating and drinking, which made us feel way better about going even though it was obviously still going to be a risk. The bride's family then decided not to come -- not sure if it's out of caution or because they're anti-vax/anti-mask. I'm bummed but also very relieved. We're coming to the US for the first time in almost two years either way, but this way we know we will only interact with vaxxed people.
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Sep 10, 2021 08:50
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Bad Purchase posted:a lot of people will threaten to quit, but these are the same cowards scared of vaccines that have been taken by a billion people now. they'll probably be even more scared of losing their job and fall in line after a public tantrum. they're going to fake their vax documents and get charged with multiple federal crimes and the lols will just keep coming
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Sep 10, 2021 10:04
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PhazonLink posted:how did mRNA tech fly under the radar? Interestingly, bacteriophages were used fairly successfully in the USSR as an alternative to certain antibiotic therapies, it was just one of the ways that the Iron Curtain caused a sort of bifurcation in medical research approaches. As others say, mRNA (and gene therapies more broadly) have been coming down the chute for many years, but progress is slow. Even though Pharma is used to thinking in decade-plus development lifecycles, they will still be quick to put a whole therapeutic area on ice or divest assets to a competitor if there's signs that they won't be immediately profitable, or there's too much competition, or the target population doesn't allow for sufficient growth, etcetc. Thus, externalising healthcare provision to publicly traded companies is a horrible model, but it seems to be the only one there's any appetite for in the "developed world".
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Sep 10, 2021 10:21
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Failed Imagineer posted:Interestingly, bacteriophages were used fairly successfully in the USSR as an alternative to certain antibiotic therapies, it was just one of the ways that the Iron Curtain caused a sort of bifurcation in medical research approaches. Yeah, I remember phages being the Next Big Thing throughout the 90s, but I think, like mRNA, you could put a charitable spin on their lack of traction by saying that often the treatments we had were good enough that it became difficult to justify, ethically as well as financially, the kind of mass-scale testing you'd need. IIRC phages are under active investigation for multi-drug-resistant TB and MRSA but there's still a big hesitancy about them because unlike antibiotics there's no way of stopping them once they start - if you're testing a new antibiotic you can start off with tiny doses and work up and if the patient has a reaction you stop and treat the reaction, if your phage virus turns out to have an insatiable appetite for human bone marrow then there's really not much you can do about it. Similarly I remember reading about mRNA being a candidate for hyper-targeted vaccines against cancer cells and possibly HIV maybe 10 years ago when they first started trials with it (it's possible I might have that confused with another gene therapy) but again there was a big concern about the sheer scope of potential problems it could cause if you got it wrong - not the "It's going to turn all our DNA into reptilian 5G antennas" kind, but just "listen we can do literally anything with this, which means there's an almost infinite amount of ways we can badly gently caress it up" and with traditional treatments for cancer and HIV getting better and better the inherent (and I'd say mostly justifiable) conservatism of medical ethics meant it was always being kept on the back burner. With the sheer tidal waves of cash being thrown at medical research for covid though, they were able to finally prove that it works - if there can be said to be a silver lining to this pretty loving dark cloud, having a whole new class of therapies and vaccines available to humanity is going to radically change a lot of poo poo over the next few decades.
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Sep 10, 2021 10:45
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boquiabierta posted:Welp, the wedding's off now. The amount of social pressure people are feeling around this now is intense. My wife's aunt is likely going to a wedding soon because it's her childhood best friend's kid. She really doesn't want to go, but it's so hard not to given her decades-long friendship. Most of her friend's family are flying in from TX and are unvaxxed.  Even if you've fully drunk the "covid is endemic" manufactured consent from the media, people should not be having big gatherings right this moment given the ever-increasing delta caseload and the increasingly strained hospital system. Even if only the meal is maskless (which, lol, it emphatically will not be the only maskless thing in 99% of weddings), that's plenty of time to spread delta, especially if the meal is indoors.
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Sep 10, 2021 11:48
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PhazonLink posted:how did mRNA tech fly under the radar? https://www.stitcher.com/show/the-daily-10/episode/the-unlikely-pioneer-behind-mrna-vaccines-84603652 A good primer on exactly this.
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Sep 10, 2021 11:58
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Detheros posted:In a 6-3 decision... I don't see this happening. I think Thomas will be against it because he's an idiot lunatic true believer but the rest will probably desire conspicuous capitalism to resume. Not to mention it got mentioned on twitter yesterday but there is a clear divide in conservatives who realize it's all bullshit and are selling a product and the true believers. You have everyone at Fox News who is vaccinated and yet does pieces on "Is the vaccine safe??" prolefeed and then you have the radio hosts who are getting wiped out after railing against it and refusing masks and vaccines. I like to think the supreme court judges are mostly on the fox news side of the fence. Able to pick up where the bullshit meets the grift.
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Sep 10, 2021 13:15
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So is the advantage of mRNA that we can pump it out super easily vs creating the actual proteins we're targeting? I'm just trying to understand how the mRNA is such a huge breakthrough vs just injecting the protein directly. Kind of like how you could print thousands of copies a day of instructions on how to build an IKEA kitchen, but actually building the kitchen yourself would take a couple days for each one. But you can hand those instructions to a build crew that can do that poo poo in a couple hours. And then the instructions we printed get all torn up right away so the construction crew doesn't run amok renovating the whole place in ways we didn't ask them to do...
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Sep 10, 2021 13:26
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Snowglobe of Doom posted:No surprises here “MY BODY MY CHOICE!!”* *except for women gently caress this Texan ghoul.
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