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Brainiac Five
Mar 28, 2016

by FactsAreUseless
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172306/

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Brainiac Five
Mar 28, 2016

by FactsAreUseless

However,

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804177/

Brainiac Five
Mar 28, 2016

by FactsAreUseless

AARO posted:

I admitted in the OP that the actual drugs do work better than placebo in severe depression. But severe depression accounts for a very small number of the patients prescribed these drugs.

This doesn't refer to severe depression, it refers to analyzing studies conducted of first-generation SSRIs and using reported changes in depressive mood as the yardstick instead of the 57-point scale. It includes patients with moderate and severe depression. Essentially, the conclusion as found in the study is that SSRI antidepressants do have a statistically significant effect when it comes to improving depressive mood over placebo, which in turn suggests that the 57-point scale may be ineffective. Neither is actually conclusive and final when it comes to determining the effectiveness of the treatments, though the meta-analysis does perforate the serotonin reuptake model of depression.

Brainiac Five
Mar 28, 2016

by FactsAreUseless

AARO posted:

So what to make of the meta-analysises which prove the opposite?

Well, you didn't read the meta-analysis, then, because the meta-analysis is predicated on the use of the 57-point scale to prove clinical efficacy and the 2015 study challenges the value of the 57-point scale for analyzing depression.

AARO posted:

Gald you're feeling ok today but it's proven that they may eventually increase your desire to kill yourself at some later point.

This is also not in the meta-analysis, though it's (irresponsibly) said in the abstract.

Brainiac Five fucked around with this message at 20:04 on Jun 4, 2016

Brainiac Five
Mar 28, 2016

by FactsAreUseless

Gazpacho posted:

Please don't try this at home, validating crazies has a very poor track record of helping them.

"A primary treatment goal during the stable phase is to enable the patient to continue the recovery
process and to achieve the goals of improved functioning and quality of life. To the degree
to which active positive symptoms impair functional capacity, medications that reduce positive
symptoms may improve functioning. However, research indicates consistently that positive
symptoms show a low correspondence with functional impairments among patients with
schizophrenia (190). Rather, it is the negative symptoms and cognitive impairments that are
more predictive of functional impairment (191)."

From the 2004 APA Guidelines on treating schizophrenia.

Brainiac Five
Mar 28, 2016

by FactsAreUseless

Gazpacho posted:

Can you bold the part of that that says "help schizophrenics by agreeing with them that the lizard people are real"?

The actual guidelines for care only care about positive symptoms, namely hallucinations and delusions, to the extent that these are functional impairments. Clinical evidence shows that they are only loosely correlated with functional impairment.

In addition, the care guidelines emphasize the need for a therapeutic alliance between the psychatrist and patient.

Now, this requires reading and you have undoubtedly sworn a dread and terrible oath not to read things on pain of death, but in conclusion, psychiatrists are discouraged from emphasizing hallucinations or delusions are unreal until the patient comes to that conclusion on their own, except where these impair the ability of the patient to live independently. This is because psychiatrists are doctors rather than members of the Ministry of Love.

Brainiac Five
Mar 28, 2016

by FactsAreUseless

Gazpacho posted:

I don't believe that your sources say that it should be a tactic of therapy to actively affirm a patient's delusions, but if they do say that, then they are bad.

I'm glad that you're such an intellectual titan that you stand firmly convinced that the psychiatrist should start pummeling the recalcitrant schizophrenic with their fists to exorcise the hallucinations, and feel no need to consider any evidence to the contrary, code jockey.

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Brainiac Five
Mar 28, 2016

by FactsAreUseless

Gazpacho posted:

I'm sorry that you are so incompetent at perceiving the difference between "active affirmation" and "passive acceptance" that you feel compelled to use plat powers to win this silly argument.

Huh, so you're willing to split hairs over this difference, in order to win this argument, while imputing your desires onto me, because you are cowardly.

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