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poll plane variant
Jan 12, 2021

by sebmojo
WTF is up with moderna anyway, bc none of the countries that actually track covid used it I feel like we don't know poo poo about it, and it's not managed to secure approval or boosters

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PostNouveau
Sep 3, 2011

VY till I die
Grimey Drawer

poll plane variant posted:

WTF is up with moderna anyway, bc none of the countries that actually track covid used it I feel like we don't know poo poo about it, and it's not managed to secure approval or boosters

Good at making vaccines, bad at filling out government paperwork

poll plane variant
Jan 12, 2021

by sebmojo

PostNouveau posted:

Good at making vaccines, bad at filling out government paperwork

Like I know "here's a heroic dose of mRNA glhf" is their whole thing but come on

gradenko_2000
Oct 5, 2010

HELL SERPENT
Lipstick Apathy

Business Gorillas posted:

Consider keto, friend

Went back on it after 9 months of trying to wrestle my low metabolism with my doctor and lost more weight in the first week than the past 9 months of tinkering with thyroid medicine

I'm already doing IF (no food before 1 PM, no food after 9 PM) and doing 5 km walks for a little over a month now. Both also things I picked up from nice goons in this thread.

but thank you for the concern

Greg Legg
Oct 6, 2004

poll plane variant posted:

Like I know "here's a heroic dose of mRNA glhf" is their whole thing but come on

Is the effectiveness of the moderna vaccine over pfizer really because it's just bigger?? That's pretty funny.


EDIT: I'm a huge dumbass when it comes to this stuff and I have no idea if it's more effective or not.

Greg Legg fucked around with this message at 14:32 on Sep 13, 2021

post COVID
Mar 5, 2007

free college, free healthcare, free Shmurda


Morbus posted:

That's fair enough. Unfortunately, the institutions (like the CDC) who are supposed to take scientific data and then synthesize & communicate policy have been pretty much making GBS threads the bed. The media are mostly useless and/or straight up lying (to you, themselves, or both). And twitter, or social media more generally, is full of crazy.

These papers aren't written for a general (or even non-specialist) audience, but if people don't try to engage with the primary sources the "interpreters" they are left with are usually some combination of disingenuous, stupid, unreliable, or crazy. I don't think its fair or appropriate that people should have to rummage through scientific papers to know what the gently caress is going on, but in the absence of functioning institutions we get to chose between helplessness or DIY. Failing states sure are great.

Anyway that paper covers a particular mechanism for SARS-CoV-2 evading the immune systems. Pretty much all viruses evade the innate and adaptive immune systems in some way. The MHC downregulation described in the paper is a way for the virus to, in a broad way, reduce the effectiveness of T-cells by interfering with signaling. They mention how some patients who recover from covid still appear to (maybe) be carriers, and those patients show signs of T-cell disfunction. Maybe this MHC downregulation has something to do with it. Maybe it doesn't. It's interesting, but its a huge crazy leap to go from there to "my long covid symptoms are because covid actually lasts forever".

At the end of the day, viruses which persist in the host by damaging, suppressing, or evading the immune system end up doing one of two things. Either they go into a latent phase, stop producing infectious virus, mostly shut the gently caress up, and occasionally cause trouble (like herpes). Or, they keep replicating, increasingly building up until the host succumbs or generally gets hosed up (like HIV, or FIP, which that twitter thread mentions). Neither of these is happening in long covid patients, and really only the second option seems possible with SARS-CoV-2--which would be easy to detect and would not go unnoticed. On the other hand, it is not mysterious that a virus which can cause hypoxia + widespread damage to the vascular system, lungs, kidneys, heart, and brain sometimes results in lingering or permanent symptoms.

good post

poll plane variant
Jan 12, 2021

by sebmojo

Greg Legg posted:

Is the effectiveness of the moderna vaccine over pfizer really because it's just bigger?? That's pretty funny.

Is it more effective?

Greg Legg
Oct 6, 2004
I have no idea

poll plane variant
Jan 12, 2021

by sebmojo
It was also given farther apart. Did places that delayed second doses do better?

Spoondick
Jun 9, 2000

we have entered the endemic phase of covid which means you have to pay for your tests and vaccines yourself

Pittsburgh Fentanyl Cloud
Apr 7, 2003


I got Moderna, 2nd dose in late February. I didn't have a huge reaction to either shot besides feeling a bit run down and tired but I also haven't gotten sick. Who knows

lil poopendorfer
Nov 13, 2014

by the sex ghost

Business Gorillas posted:

Consider keto, friend

Went back on it after 9 months of trying to wrestle my low metabolism with my doctor and lost more weight in the first week than the past 9 months of tinkering with thyroid medicine

that's largely water. Glucose is stored with water in a 1:3 ratio, as glycogen. As your glycogen stores are depleted and converted to usable energy, the water is released and excreted.

Testvan
Nov 10, 2003
If vaccinated, enroll in the CDC v-safe health checker

poll plane variant
Jan 12, 2021

by sebmojo

lil poopendorfer posted:

that's largely water. Glucose is stored with water in a 1:3 ratio, as glycogen. As your glycogen stores are depleted and converted to usable energy, the water is released and excreted.

I thought energy was stored as jet fuel, in the wings. Paging Doctor Schnorkles!

net work error
Feb 26, 2011

When do we see the NFL week 1 spike? Beginning of October?

McNugget Buddy
Aug 14, 2021

by Jeffrey of YOSPOS
https://twitter.com/petemuntean/status/1437404797590720516

https://twitter.com/CNN/status/1437389604588490754

quote:

Fauci, the director of the National Institute of Allergy and Infectious Diseases, said if more people aren't persuaded to get vaccinated by messaging from health officials and "trusted political messengers," additional mandates from schools and businesses may be necessary.

"I believe that's going to turn this around because I don't think people are going to want to not go to work or not go to college ... They're going to do it," Fauci told CNN's Jen Christensen during an interview at the NLGJA, the Association of LGBTQ Journalists, convention Sunday. "You'd like to have them do it on a totally voluntary basis, but if that doesn't work, you've got to go to the alternatives."

Lastgirl
Sep 7, 1997


Good Morning!
Sunday Morning!

Business Gorillas posted:

tbf not protecting the vaccinated is a great way to get vaccine resistant variants

we could, of course, think about our actions and how capitalist consumption is a direct health risk now. since that won't happen, gotta have our vaccine enclaves instead

:hmmrona: exactly

mastershakeman
Oct 28, 2008

by vyelkin

Spoondick posted:

we have entered the endemic phase of covid which means you have to pay for your tests and vaccines yourself

I still can't get over having to pay $25 for a pair of lovely home tests. I'm never gonna home test again and going to a walk-in place takes hours of waiting

Testvan
Nov 10, 2003
NYC's experiment begins today: public school starts (1 million kids) with no remote option
NYC also forced all city workers (300k people) to back into the office today


"Our kids need to be in school and it's unbelievable that some kids haven't seen the inside of a classroom for a year and a half," the mayor said Thursday. "There are massive consequences to that, including health care consequences. The healthiest, best place for kids to be is in school."

"We believe this is an extraordinarily safe environment," de Blasio responded. "We've proven it and the most important thing is our kids have to come back."

mdemone
Mar 14, 2001

poll plane variant posted:

Is it more effective?

Yes, it seems to maintain titer development longer than Pfizer, and it is probably due to the amount of mRNA being about three times larger in the Moderna product.

Wamsutta
Sep 9, 2001

wife stopped in CVS this morning and they have a sign up saying no covid testing due to lack of staff, also they had literally an empty shelf instead of having advil in stock

probably ok

Pittsburgh Fentanyl Cloud
Apr 7, 2003


Testvan posted:

NYC's experiment begins today: public school starts (1 million kids) with no remote option
NYC also forced all city workers (300k people) to back into the office today


"Our kids need to be in school and it's unbelievable that some kids haven't seen the inside of a classroom for a year and a half," the mayor said Thursday. "There are massive consequences to that, including health care consequences. The healthiest, best place for kids to be is in school."




Hahah, yeah, if only we'd done something like a mandatory strict lockdown, contract tracing, and border / airport quarantines so the kids didn't have to be out of school for a year and a half.

Thoguh
Nov 8, 2002

College Slice
https://twitter.com/DrEricDing/status/1437306857266294790?s=19

Honestly anyone on a plane right now should just assume that they are exposed.

McNugget Buddy
Aug 14, 2021

by Jeffrey of YOSPOS

Testvan posted:

"We believe this is an extraordinarily safe environment," de Blasio responded. "We've proven it and the most important thing is our kids have to come back."

Mayor Koch Brothers

TehSaurus
Jun 12, 2006


I mean obviously these people are insane for going to a football game in the middle is a pandemic but this is the forum that created the No Joe gang tag. That chant is very cspam!

McNugget Buddy
Aug 14, 2021

by Jeffrey of YOSPOS

TehSaurus posted:

I mean obviously these people are insane for going to a football game in the middle is a pandemic but this is the forum that created the No Joe gang tag. That chant is very cspam!

Joe Biden does not discriminate when it comes to killing Americans

We are all his children

Steve Yun
Aug 7, 2003
I'm a parasitic landlord that needs to get a job instead of stealing worker's money. Make sure to remind me when I post.
Soiled Meat
It’s time to stop living in fear and to live our lives



Shang Chi was pretty good

genericnick
Dec 26, 2012

mastershakeman posted:

I still can't get over having to pay $25 for a pair of lovely home tests. I'm never gonna home test again and going to a walk-in place takes hours of waiting

You mean two tests and not packs of tests, right? That's an absurd rip-off. As far as I can see the most expensive pack of five here in Euroland is 50€ with a few going as low as 8€.

fits my needs
Jan 1, 2011

Grimey Drawer
https://twitter.com/TB_Times/status/1437417422609342466?s=20

Death By The Blues
Oct 30, 2011
remember those thumb parody films from the 2000s? He looks like a character.

Steve Yun
Aug 7, 2003
I'm a parasitic landlord that needs to get a job instead of stealing worker's money. Make sure to remind me when I post.
Soiled Meat

Vaccinated people have nothing to worr-

quote:

Sgt. Gobernik had received the vaccine and took the virus seriously, his coworkers said. He wore his mask and made sure his children did, too. His wife, Daisy Gonzalez-Gobernik, is a nurse at the Plant City hospital where he would fight for his life. Still, in mid-August, Gobernik fell ill with the Delta variant.

Iron Crowned
May 6, 2003

by Hand Knit

Wamsutta posted:

wife stopped in CVS this morning and they have a sign up saying no covid testing due to lack of staff, also they had literally an empty shelf instead of having advil in stock

probably ok

There are definitely weird supply chain issues for a while now. Canned cat food was basically cleaned out at Meijer this weekend. Normally you'll find a single brand that's sold out, but this was the first time I had seen it across all brands.

Kroger was out of plastic bags(I like to use the single use bags for trash bags at home :shrug: ), so I ended up with a paper bag. At first I assumed it was the phaseout, but that's apparently not until 2025 (because people bitched about it).

Nothus
Feb 22, 2001

Buglord
https://twitter.com/TheAtlantic/status/1437417575231725569?s=20

Glancing at the title, you'd think this would be a sober reflection on the failure of most of the world to respond to covid.

But it's actually a hatchet-job on China, the one country to beat the pandemic.

fits my needs
Jan 1, 2011

Grimey Drawer

Iron Crowned posted:

There are definitely weird supply chain issues for a while now. Canned cat food was basically cleaned out at Meijer this weekend. Normally you'll find a single brand that's sold out, but this was the first time I had seen it across all brands.

Kroger was out of plastic bags(I like to use the single use bags for trash bags at home :shrug: ), so I ended up with a paper bag. At first I assumed it was the phaseout, but that's apparently not until 2025 (because people bitched about it).

are there supply shortages at the strip club

Pittsburgh Fentanyl Cloud
Apr 7, 2003



heh, more like Goobernik. See ya bitch

Iron Crowned
May 6, 2003

by Hand Knit

genericnick posted:

You mean two tests and not packs of tests, right? That's an absurd rip-off. As far as I can see the most expensive pack of five here in Euroland is 50€ with a few going as low as 8€.

:lmao:

You obviously don't know anything about America

mod sassinator
Dec 13, 2006
I came here to Kick Ass and Chew Bubblegum,
and I'm All out of Ass

Mayor Dave posted:

Thank you for wearing a mask Mr president



do secret service agents really just wear piece of poo poo cloth masks? good god what a useless org

Iron Crowned
May 6, 2003

by Hand Knit

fits my needs posted:

are there supply shortages at the strip club

I didn't ask

mod sassinator posted:

do secret service agents really just wear piece of poo poo cloth masks? good god what a useless org

Cloth masks are a hallmark of "the company makes me wear this when I'm not sitting at my desk"

fits my needs
Jan 1, 2011

Grimey Drawer

genericnick posted:

You mean two tests and not packs of tests, right? That's an absurd rip-off. As far as I can see the most expensive pack of five here in Euroland is 50€ with a few going as low as 8€.

lol

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Pittsburgh Fentanyl Cloud
Apr 7, 2003


genericnick posted:

You mean two tests and not packs of tests, right? That's an absurd rip-off. As far as I can see the most expensive pack of five here in Euroland is 50€ with a few going as low as 8€.

Abbott bought back millions of their Binax fast tests in June and destroyed them lmao


https://www.nytimes.com/2021/08/20/us/abbott-covid-tests.html

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