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bring back old gbs posted:yeh we want spider guts vido https://www.youtube.com/watch?v=Fx8TcGrCOSI
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Oct 20, 2018 18:05
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That doesn't even make sense either, you just need like one spider, and it can even be a dead one. That poo poo is just crush porn.
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Oct 20, 2018 18:08
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what? I think this dude can probably accomplish what he's explaining. I mean he bought like 6 black widows and he did buy dead ones but probably because he wants backups just in case he accidentally trips and knocks all the silk yeasts down the drain or something
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Oct 20, 2018 18:20
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SniperWoreConverse posted:what? I think this dude can probably accomplish what he's explaining. I mean he bought like 6 black widows and he did buy dead ones but probably because he wants backups just in case he accidentally trips and knocks all the silk yeasts down the drain or something He can't, and if you really think he can, then do I have a deal for you! It's this type of oil that will cure arthritis, eczema, and warts! PM me with your credit card for a sample!
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Oct 20, 2018 18:23
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idk he said plasmid an enzyme a bunch of times he seems like he knows what's up
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Oct 20, 2018 18:25
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Most boring derail ever.
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Oct 20, 2018 18:37
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Oct 20, 2018 18:58
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SniperWoreConverse posted:what? I think this dude can probably accomplish what he's explaining. I mean he bought like 6 black widows and he did buy dead ones but probably because he wants backups just in case he accidentally trips and knocks all the silk yeasts down the drain or something i agree, he also had the black kind of scientist gloves not the standard white kind a scrub tier would buy
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Oct 20, 2018 19:08
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If he had only the blue ones I'd deff be on the fence
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Oct 20, 2018 19:12
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Phobos Anomaly posted:Most boring derail ever. First, turn on your monitor Then, don't sign your posts Then, gently caress off or post content
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Oct 20, 2018 19:24
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mycomancy posted:Yup. Also, yeast are fungi, not bacteria. They make alcohol of course they’re fun guys 
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Oct 20, 2018 19:27
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The Bloop posted:First, turn on your monitor So who pissed in your cheerios today?
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Oct 20, 2018 19:42
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SniperWoreConverse posted:
The engineered CRISPR (or rather the cas9 protein but everyone just calls the whole system CRISPR because it sounds rad) that everyone uses takes a short piece of rna called the guide rna, matches that up with the DNA sequence, and cuts the DNA. If you give it some extra DNA with sequences matching the area around the cut site, the cell can incorporate the foreign DNA into its own genome when it repairs the cut. More complex organisms have many more cells to transform, and it is more difficult to successfully transform them. I'm not sure what kind of efficiencies people are getting but I'm sure it varies greatly depending on the procedure used. If you know how restriction enzymes work for gene editing it's basically the same thing, but CRISPR can be programmed to recognize any sequence you provide rather than being limited to one particular recognition sequence.
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Oct 20, 2018 19:44
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When I internalized my mom was gonna die from cancer. I was working as a security guard at the time so it wasn't ideal.
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Oct 20, 2018 19:47
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If you didn't enjoy the little derail about crushing spiders and putting their milk in yeast I feel nothing but contempt for you.
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Oct 20, 2018 19:48
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Grevling posted:If you didn't enjoy the little derail about crushing spiders and putting their milk in yeast I feel nothing but contempt for you. In a thread full of lengthy political derails and slap fights crushed spider milk yeast is the line in the sand.
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Oct 20, 2018 19:51
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Yeah I don't know poo poo I basically heard a podcast where someone used the term gene drive and they acted like you could force an organism to accept alterations for all subsequent generations even if there's pretty strong selection pressure against it. Like the new genes are driven in permanently and will spread to the entire population. So it sounds like probably crisper is part of that but not that. I think there was a part where a dude realized this could be used to make all mosquitoes extinct somehow? and then he was like badass no more dengue but then he was like holy poo poo terrifying ecological consequences. It made sense the way they explained it but I honestly don't remember. This is why we need to start the GBS Institute of Goonalogical Sciences so we can know what the gently caress and as a positive side effect rebuild Lowtax spine by injecting crushed up crabs and tree bark into mice from the pet store. Still the "discover new antibiotics in the the comfort of your own home" this seems extremely capitalism.png to me.
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Oct 20, 2018 19:59
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CRISPR is one way of making gene drives work but they can use basically any gene editing technique to introduce them. They work by introducing a suite of genes including the nuclease (ie cas9 or whatever else), the guide sequence, and whatever gene you're inserting, and making that whole deal a part of the native chromosome. Then the cell will use one chromosome as a template to copy that poo poo over to the other, and it'll do this every generation, so each daughter cell gets forcefully made homozygous. Perhaps we could harness this technology to save the frogs from homosexuality...
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Oct 20, 2018 20:11
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Genetic engineering is not at that kind of stage yet. Maybe when we figure out artificial viruses to do our gene editing and not painstaking repeated laboratory procedures
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Oct 20, 2018 20:12
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modified viruses are already one of the methods used to transform cells lol. adenoviruses mostly but maybe also lentiviruses?
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Oct 20, 2018 20:17
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Phobos Anomaly posted:So who pissed in your cheerios today? No one at all and I'm really depressed about it and lonely okay?
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Oct 20, 2018 20:24
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Tastykake posted:modified viruses are already one of the methods used to transform cells lol. adenoviruses mostly but maybe also lentiviruses? Im aware but we aren't quite at the runaway environmental disaster stage
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Oct 20, 2018 20:36
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Larry Parrish posted:Im aware but we aren't quite at the runaway environmental disaster stage It likely won't ever get to that point, using nucleases invaribly results in a fitness defect, either from the DNA cutting, the expression of Cas9, or some unforeseen effect from the edit being installed. Natural organisms will just outcompete the edited ones...well, usually.
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Oct 20, 2018 20:53
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mycomancy posted:It likely won't ever get to that point, using nucleases invaribly results in a fitness defect, either from the DNA cutting, the expression of Cas9, or some unforeseen effect from the edit being installed. Natural organisms will just outcompete the edited ones...well, usually. life... finds a way 
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Oct 20, 2018 21:07
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SniperWoreConverse posted:Yeah I don't know poo poo I basically heard a podcast where someone used the term gene drive and they acted like you could force an organism to accept alterations for all subsequent generations even if there's pretty strong selection pressure against it. Like the new genes are driven in permanently and will spread to the entire population. So it sounds like probably crisper is part of that but not that. Mosquitos and stuff are interesting - there's poo poo loads of mosquitos that occupy the same ecological niche, but only Anopheles asgyptii carries malaria so you can theoretically do some horrible gene thing to wipe out just one species without collapsing the entire thing. It's still kind of hairy, and gives me the cold sweats.
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Oct 20, 2018 21:33
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Strom Cuzewon posted:Mosquitos and stuff are interesting - there's poo poo loads of mosquitos that occupy the same ecological niche, but only Anopheles asgyptii carries malaria so you can theoretically do some horrible gene thing to wipe out just one species without collapsing the entire thing. Worth it IMO. We are already hosed for a dozen other reasons. Giving 2nd and 3rd world countries a break from Malaria would be a big help.
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Oct 20, 2018 21:36
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MRC48B posted:Worth it IMO. We are already hosed for a dozen other reasons. Giving 2nd and 3rd world countries a break from Malaria would be a big help. Yeah, knocking out malaria would be a phenomenal thing. Is it malaria or trypanosomes where the host only mates once in life? Can't remember my insects. So you can release a bunch of sterile males and it implodes the vector population. That always felt a lot less likely to have unforseen consequences
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Oct 20, 2018 21:43
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"Hey guys let's extinct an animal that may or may not cause global ecological collapse, whaddyathink?" Lol
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Oct 20, 2018 21:53
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Outrail posted:"Hey guys let's extinct an animal that may or may not cause global ecological collapse, whaddyathink?" You DO realize we're talking about a single species of mosquito, right?
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Oct 20, 2018 21:54
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Strom Cuzewon posted:Mosquitos and stuff are interesting - there's poo poo loads of mosquitos that occupy the same ecological niche, but only Anopheles asgyptii carries malaria so you can theoretically do some horrible gene thing to wipe out just one species without collapsing the entire thing. Apparently it is also pretty invasive. Fate is sealed, once I release The Death Gene (FKDfrvr-2) that I carefully computed and then grew in an old tuna can the world will be free from this plague. Another fun gene thing that is a little bit capitalism is some pet store in Germany kept all their crayfish in a big vat, and the different species hosed each other until life found a way and there's now a parthenogenic ultra hybrid clone that asexually lays female eggs and has a complete functional life cycle. And it broke out and now it's spread all over the fuckin place completely out of control.
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Oct 20, 2018 22:08
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Beware the deadly marmorkrebs
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Oct 20, 2018 22:11
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It's okay we're gonna extinct a whole lot more than just one species.
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Oct 20, 2018 22:19
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Shima Honnou posted:It's okay we're gonna extinct a whole lot more than just one species.
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Oct 20, 2018 22:28
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Be sure to print your extinction bingo cards before the 2020 election
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Oct 20, 2018 23:18
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lmao take a quick look at all the horrible poo poo humanity is doing to the global ecosystem and then ask yourself if anyone is gonna go to bat for goddamn mosquitos
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Oct 20, 2018 23:35
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The acronym CRISPR always makes me hungry for raw baby carrots and that’s extremely not cool
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Oct 20, 2018 23:52
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instead of wiping out mosquitoes why don't we just cross humans with eels so we emit an electric field that kills any insects that come into contact with us. ever see an eel with a mosquito bite? yeah, didn't think so. dumb idiot science dorks
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Oct 21, 2018 02:00
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Communist Walrus posted:instead of wiping out mosquitoes why don't we just cross humans with eels so we emit an electric field that kills any insects that come into contact with us. ever see an eel with a mosquito bite? yeah, didn't think so. dumb idiot science dorks  this will also help curb our reliance on fossil fuels
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Oct 21, 2018 02:01
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 cybernetics though, random electric zaps would fry your poo poo p. quick
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Oct 21, 2018 02:09
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Lambert posted:It's a great thing balloon manufacturers were lobbying the government to keep selling off the national helium reserve. I work in biopharma packaging and everyone wants leak testing to make sure there are no holes bigger than a handful of of microns. I'm struggling to convince them that extruded film doesn't have pinholes and any manufacturing defects will be big enough to detect using other methods but it's difficult.
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Oct 21, 2018 02:14
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