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PederP
Nov 20, 2009

Dick Wolf posted:

So as a nurse I'm curious why so many are convinced Plaquenil and Azithromycin are miracle cures based on that one very limited study. Anybody here a physician, especially rheumatologist or infectious disease? Maybe Plaquenil would help with inflammation from the virus and the body's response to it, but there are many drugs that fight inflammation, like steroids that are often used in severe respiratory infection and COPD. I think Covid tends to cause secondary infection in the lungs, often some form of pneumonia, so Azithromycin does help with upper respiratory infection, but wouldn't it make more sense to culture at that point to find out what the infectious bacteria/fungus is and treat accordingly? All seems too convenient that these two medications magically cure someone from a viral infection. I would think some sort of anti-viral may help, but who knows?

Not a doctor, but my wife has been on Plaquenil for decades - it's not anti-inflammatory. It's a DMARD (Disease-Modifying-Anti-Rheumatic-Drug), which used to be classified as an immunosuppressive. Noone really knows why it works wonders for Lupus patients. The way it affects the symptomology of my wife is by massively reducing the pain she feels in joints and lungs - after approx. 2-3 weeks of piling up in her system. If she stops taking it or reduces her dose, the pain goes up after 2-3 weeks. She's currently on a reduced dose - because the access to the medicine was greatly restricted *back in January*.

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Zero VGS
Aug 16, 2002
ASK ME ABOUT HOW HUMAN LIVES THAT MADE VIDEO GAME CONTROLLERS ARE WORTH MORE
Lipstick Apathy

Utter rubbish, science has proven the only effective cure is forsythia

steinrokkan
Apr 2, 2011



Soiled Meat

Im Ready for DEATH posted:

Humans are social creatures. Even if it kills us, we want to talk to and interact with others. :shrug:

I love how all these posts always go "So I went for a walk in the park this morning, and let me tell you, people are terribly selfish, the place was absolutely crowded!"

Marmaduke!
May 19, 2009

Why would it do that!?
It's similar to the "I have to buy all the toilet roll before idiots panic buy it all!" mindset

Platystemon
Feb 13, 2012

BREADS
It’s only hoarding if it’s from the Eversong Woods region of the Eastern Kingdoms.

Otherwise it’s just sparkling night elves.

Platystemon
Feb 13, 2012

BREADS
It’s only hoarding if it’s attached to a castle.

Otherwise it’s jettying.

stephenthinkpad
Jan 2, 2020

Lolie posted:

About 70,000 people in the USA died from the 1958-1958 Asian flu pandemic. Given the increase in population over the last twenty years, 100,000 from this pandemic would be a near miracle.

But Italy lost 10k bodies already and tgeir pandemic may not even peak yet, and Italy has about roughly the population of north eastern US states.

So really you should compare to the Spanish flu, which killed over 600k Americans.

stephenthinkpad fucked around with this message at 09:01 on Mar 30, 2020

numberoneposter
Feb 19, 2014

How much do I cum? The answer might surprise you!

buckle up my buddies

were about to hit monday

i really dont want to go to work but its my duty

Noise Complaint
Sep 27, 2004

Who could be scared of a Jeffrey?
turns out beans go well with sardines

Enjoy my Apocalypse meal "Beans and 'Dines":

1 can of Garbanzo Beans
1 tin of Sardines
hot sauce to taste

Heat until warm. Consume.

If this doesn't help with keeping people 6 feet away, nothing will.

Thank you and follow for more recipes.

Instruction Manuel
May 15, 2007

Yes, it is what it looks like!

Noise Complaint posted:

turns out beans go well with sardines

Enjoy my Apocalypse meal "Beans and 'Dines":

1 can of Garbanzo Beans
1 tin of Sardines
hot sauce to taste

Heat until warm. Consume.

If this doesn't help with keeping people 6 feet away, nothing will.

Thank you and follow for more recipes.

argh frick that sounds repulsive. I'll video myself eating it and play it on loop outside my house. that should keep any would be raiders away. It'll probably taste pretty drat actually

Noise Complaint
Sep 27, 2004

Who could be scared of a Jeffrey?

Wamdoodle posted:

argh frick that sounds repulsive. I'll video myself eating it and play it on loop outside my house. that should keep any would be raiders away. It'll probably taste pretty drat actually

It's a actually a super good and healthy thing, except usually with a bunch of fresh stuff like parsley and lemon that get bought out because boomers get their head start hour in the local supermarkets. So now I'm just stuck with the beans and 'dines.

Algol Star
Sep 6, 2010

Dick Wolf posted:

So as a nurse I'm curious why so many are convinced Plaquenil and Azithromycin are miracle cures based on that one very limited study. Anybody here a physician, especially rheumatologist or infectious disease? Maybe Plaquenil would help with inflammation from the virus and the body's response to it, but there are many drugs that fight inflammation, like steroids that are often used in severe respiratory infection and COPD. I think Covid tends to cause secondary infection in the lungs, often some form of pneumonia, so Azithromycin does help with upper respiratory infection, but wouldn't it make more sense to culture at that point to find out what the infectious bacteria/fungus is and treat accordingly? All seems too convenient that these two medications magically cure someone from a viral infection. I would think some sort of anti-viral may help, but who knows?

There's a bunch of related compounds (incl. quinine, chloroquine and hydroxychloroquine) that have long been suspected to have broad spectrum antiviral effects, possibly due to changes in the intracellular environment making it more hostile to viral replication. There's a bunch of in vitro studies looking at them against a variety of viruses but little clinical trial evidence. They're less of a shot in the dark and a lot of people are primed to believe their effectiveness. They're also mass producible and some are potentially safe enough to widely prescribe with limited supervision. This makes them much more attractive possibly than certain other drugs which are under investigation about which much less is known.

The problem will be getting good quality evidence and poorly designed trials could easily wrongly point one way or the other, there have already been both for hydroxychloroquine. It's possible in covid that antivirals are only useful early on, since the severe late disease seems to be immune mediated but it's difficult to predict which patients will get the severe disease so it might need to be given to a lot of people who would get better anyway. This is going to muddy the waters a lot and make it more difficult to demonstrate benefit, especially in small poorly conducted trials.

numberoneposter
Feb 19, 2014

How much do I cum? The answer might surprise you!

https://www.youtube.com/watch?v=siO6dkqidc4

numberoneposter
Feb 19, 2014

How much do I cum? The answer might surprise you!

im going to work tomorrow

Snowglobe of Doom
Mar 30, 2012

sucks to be right

steinrokkan posted:

I love how all these posts always go "So I went for a walk in the park this morning, and let me tell you, people are terribly selfish, the place was absolutely crowded!"

There was an opinion piece in our local news media where a woman read that the local beaches were closed with the exception that "people will still be able to access the beaches as a thoroughfare, such as for a run or walking a dog" or swimming for exercise so she headed down there with her daughter to meander along the water's edge because they were bored at home (ie: not running or walking a dog or swimming, specifically visiting the beach for fun and not using it for exercise) and was shocked and appalled when the cops politely told her to bugger off.


To be fair the local council's statement was pretty badly worded

Pistol_Pete
Sep 15, 2007

Oven Wrangler

Noise Complaint posted:

It's a actually a super good and healthy thing, except usually with a bunch of fresh stuff like parsley and lemon that get bought out because boomers get their head start hour in the local supermarkets. So now I'm just stuck with the beans and 'dines.

Sardines with lemon juice, salt and pepper and hot sauce loving rule. Serve mixed into pasta, rice, or also beans, I guess.

Shaman Tank Spec
Dec 26, 2003

*blep*



Drunk Nerds posted:

The more I think about it the funnier it gets. Assuming OP was male, the drunk guy considered being asked to step back as "homo."

I am male, yes.

In less weird Finnish news, our daily new confirmed cases have peaked and started to turn downwards for the first time, so it looks like social isolation is working. Now of course the worry is that people think "yeah we beat corona" and go back to normal immediately, loving everything up.

Pistol_Pete
Sep 15, 2007

Oven Wrangler
The moment I'm allowed to, I'm absolutely planning to find the noisiest, most crowded pub I can and drink myself into blissful oblivion.

Lambert
Apr 15, 2018

by Fluffdaddy
Fallen Rib

Pistol_Pete posted:

The moment I'm allowed to, I'm absolutely planning to find the noisiest, most crowded pub I can and drink myself into blissful oblivion.

Same, but the pub is a tavern in World of Warcraft.

Snowglobe of Doom
Mar 30, 2012

sucks to be right

Rectal Death Adept posted:

The US had half the deaths on Sunday as it did on Saturday. That's good right?

Or is reporting not done yet or something.

It might be a reporting issue or it might be a sign that the preventive measures taken a few weeks ago (social distancing, washing hands, etc) are starting to take effect but there's no real way to know if things are changing from just a single day's results, we have to wait at least a few more days to see any real sign of a changed trend.

God forbid that people go "Welp, crisis is over, back to normal life!" and immediately break isolation even if the graph is actually flattening

sassassin
Apr 3, 2010

by Azathoth
Not as many people die (officially) on Sundays. Don't get excited about low numbers over a weekend.

ilmucche
Mar 16, 2016

What did you say the strategy was?

Pistol_Pete posted:

The moment I'm allowed to, I'm absolutely planning to find the noisiest, most crowded pub I can and drink myself into blissful oblivion.

I'm interested in seeing how the confinement period ends in france. Surely a phased ending will have to be done, otherwise the bars will get packed out, everyone will meet up and the one person who isn't showing symptoms will then infect everyone all over again.

HerStuddMuffin
Aug 10, 2014

YOSPOS

Noise Complaint posted:

turns out beans go well with sardines

Enjoy my Apocalypse meal "Beans and 'Dines":

1 can of Garbanzo Beans
1 tin of Sardines
hot sauce to taste

Heat until warm. Consume.

If this doesn't help with keeping people 6 feet away, nothing will.

Thank you and follow for more recipes.
Mixing food talk with treatment talk. Garlic is not a miracle cure for the roni, but it is excellent in warding it off if you don’t already have it.
By that I mean that I eat a lot of garlic and people stay as far from me as they can.

Being an rear end in a top hat to everyone also helps slow the spread of the disease, through a similar mechanism.

Cacafuego
Jul 22, 2007

I keep reading stories about doctors and nurses being fired for speaking up about their hospital’s lack of PPE or otherwise lovely administrative behaviors.

I can’t imagine a better position to get fired from, especially if they were putting them in danger every day. Oh no, I don’t know who’s going to hire an out of work ER doctor/nurse in the middle of a pandemic

Snowglobe of Doom
Mar 30, 2012

sucks to be right

ilmucche posted:

I'm interested in seeing how the confinement period ends in france. Surely a phased ending will have to be done, otherwise the bars will get packed out, everyone will meet up and the one person who isn't showing symptoms will then infect everyone all over again.

Yeah if any country/state/county fucks up the restart there'll just be a second wave of infections, but there's no way to know how badly they hosed it up until roughly a week later when people start showing symptoms and then roughly a week after that when people start dying again.

Platystemon
Feb 13, 2012

BREADS
Russia straight‐up ran out of booze on V‐E day.

Lambert
Apr 15, 2018

by Fluffdaddy
Fallen Rib

Cacafuego posted:

I keep reading stories about doctors and nurses being fired for speaking up about their hospital’s lack of PPE or otherwise lovely administrative behaviors.

I can’t imagine a better position to get fired from, especially if they were putting them in danger every day. Oh no, I don’t know who’s going to hire an out of work ER doctor/nurse in the middle of a pandemic

I think the managerial class might not be comprised of the smartest people.

Nessa
Dec 15, 2008

Chief McHeath posted:

My aunt is a loving nurse at a Veteran's Affairs facility and she shares poo poo like this on Facebook at least a few times a week.

My cousin, who has also worked as a nurse, shared all this info with family over text as an audio clip. I knew a lot of the inf had already been debunked.

colas
Feb 14, 2007

HerStuddMuffin posted:

By that I mean that I eat a lot of garlic and people stay as far from me as they can.

I like ginger so I bought a ton of that and just made tea. And I had a jar of minced garlic that tasted a bit bitter so I tossed that in the instant pot with a bunch of ginger because I'm silly. Made a gnarly brown spicy drink.

Pistol_Pete
Sep 15, 2007

Oven Wrangler
mmm, piping-hot garlic water.

Mnoba
Jun 24, 2010
https://www.bbc.com/news/health-52087002

mercedes made cpap machines pretty cool, in the US companies that don't have medical or military work are forced to close so lots are suddenly doing things like this which is good but still seems exploitative.

Burt Sexual
Jan 26, 2006

by Jeffrey of YOSPOS
Switchblade Switcharoo

Mnoba posted:

https://www.bbc.com/news/health-52087002

mercedes made cpap machines pretty cool, in the US companies that don't have medical or military work are forced to close so lots are suddenly doing things like this which is good but still seems exploitative.

It’s an emergency dude

Trainee PornStar
Jul 20, 2006

I'm just an inbetweener

numberoneposter posted:

im going to work tomorrow

I had to go in on friday. I hammed it up with a mask & gloves, the place was empty so I made sure to get on every CCTV I could.

Lotti Fuehrscheim
Jun 13, 2019

Austria will make simple cloth masks mandatory at supermarkets. Customers will get one at the entrance.

https://www.reuters.com/article/us-health-coronavirus-austria/austria-to-make-basic-face-masks-compulsory-in-supermarkets-idUSKBN21H16A

Lotti Fuehrscheim fucked around with this message at 13:08 on Mar 30, 2020

Mnoba
Jun 24, 2010

Burt Sexual posted:

It’s an emergency dude

I like to think companies are doing it to help ya and it keeps people working so it's double good. I guess I'm just jaded a bit how businesses normally operate.

Rectal Death Adept
Jun 20, 2018

by Fluffdaddy

Barudak posted:

Until the virus is large enough to shoot with a gun, I think this current topic of apocalypse weapon stock up has gone for long enough. There are plenty of other things ongoing to discuss.

I've not posted in GBS in a while but do the mods really just spend all day decreeing what people can and can not talk about?

I saw Burt doing it but just figured that was Burt being Burt.

Wafflecopper
Nov 27, 2004

I am a mouth, and I must scream

What's up with Wikipedia's virus map having China broken down by region all of a sudden but everyone else still being done by country?

Rad-daddio
Apr 25, 2017

Mnoba posted:

I like to think companies are doing it to help ya and it keeps people working so it's double good. I guess I'm just jaded a bit how businesses normally operate.

It happened during ww2 also. As long as they aren't price gouging mask and ventilators then it's a good thing.

Medical devices require a different set of ISO compliance regulations, but if car companies and the like are doing it then they likely have ISO 9000 or 9001 certification which is actually a little more stringent than the ISO 13485 that the medical device industry uses.

bird with big dick
Oct 21, 2015

Spinz posted:

I want to know what to carry when I'm walking with my mother and brother. A gun is not going to happen and a knife means a. I'm too close
b. they would just take it from me

A big ol pike is what I need I guess but so impractical

I'm wondering if I take one of those nordic walking poles (we have a set) sharpen an end, and use it like a walking stick but know that I could stab an rear end in a top hat if he got frisky
They are very lightweight tho

Naginata

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Burt Sexual
Jan 26, 2006

by Jeffrey of YOSPOS
Switchblade Switcharoo

Rectal Death Adept posted:

I've not posted in GBS in a while but do the mods really just spend all day decreeing what people can and can not talk about?

I saw Burt doing it but just figured that was Burt being Burt.

Multi page derails make a good thread unreadable and people don’t like it, We let discussion flow for a good while, but this isn’t the thread for that debate.

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