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CRUSTY MINGE
Mar 30, 2011

Peggy Hill
Foot Connoisseur

Woofer posted:

Maybe we can all believe that aliens* started coronavirus and stop hating each other.

*space aliens you racist

Nah, it was Batboy of weekly world news fame.

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Syrian Lannister
Aug 25, 2007

Oh, did I kill him too?
I've been a very busy little man.


Sugartime Jones

CRUSTY MINGE posted:

Nah, it was Batboy of weekly world news fame.

I miss Weekly World News

CRUSTY MINGE
Mar 30, 2011

Peggy Hill
Foot Connoisseur
At least no one is blaming world social distance champion, Bigfoot, for a virus he clearly doesn't want to spread (or catch).

That Works
Jul 22, 2006

Every revolution evaporates and leaves behind only the slime of a new bureaucracy


maffew buildings posted:

Full on powerlifting ready garage gym crew checking in

:hfive:

Hot Karl Marx
Mar 16, 2009

Politburo regulations about social distancing require to downgrade your Karlmarxing to cold, and sorry about the dnc primaries, please enjoy!
this doesnt sound good:

Scientists fear the hunt for a coronavirus vaccine will fail and we will all have to live with the 'constant threat' of COVID-19


quote:

Doubts about the possibility of a viable vaccine are based largely on the fact that no vaccine has ever been approved for use in the US or UK against other forms of coronavirus.
Whitty told the committee the evidence from other forms of coronavirus was that "immunity [to the virus] wanes relatively quickly."

Pryor on Fire
May 14, 2013

they don't know all alien abduction experiences can be explained by people thinking saving private ryan was a documentary

I walked 19.4 miles and climbed 118 flights today just wandering around, I'm not even sure where I'm loving going

Tiny Timbs
Sep 6, 2008


They've had successful vaccines in animals and there hasn't really been much of a point to pushing for human vaccines for the other coronaviruses since even the most dangerous ones waned pretty quickly. That article has a whole lot of "may be" and "might be" and "ifs" in it that mostly just seem to be doctors saying we need more information before we can figure out what's possible.

I guess if immunity wanes quickly it sounds like we'd be vaccinating every six months to a year.

Tiny Timbs fucked around with this message at 01:33 on Apr 28, 2020

CRUSTY MINGE
Mar 30, 2011

Peggy Hill
Foot Connoisseur
Yeah, just get used to the idea of it hanging around for a while. Saw something the other day saying it's now evolved into 30+ strains, but that's from the ol' google news app so who the gently caress knows. Gonna be a fun decade with the economic shitshow and the virus running wild.

That Works
Jul 22, 2006

Every revolution evaporates and leaves behind only the slime of a new bureaucracy


CRUSTY MINGE posted:

Yeah, just get used to the idea of it hanging around for a while. Saw something the other day saying it's now evolved into 30+ strains, but that's from the ol' google news app so who the gently caress knows. Gonna be a fun decade with the economic shitshow and the virus running wild.

That more just means strain types we can track as mutated from each other vs like new strains that influenza virus would have. Think more like different hair colors vs completely different species.

CRUSTY MINGE
Mar 30, 2011

Peggy Hill
Foot Connoisseur
Yeah, I realize that, but constant mutation at a high rate doesn't help with vaccine development.

Tiny Timbs
Sep 6, 2008

I doubt any of us really know what matters for vaccine development but I do know there's a fuckton of laboratories out there devoting a year's worth of resources to different types of vaccines because they sure think they can do it and I'll give them a chance before I let the Daily Bugle convince me to look up how to tie a noose.

facialimpediment
Feb 11, 2005

as the world turns

That's the doom/gloom version of this:

https://twitter.com/dandrezner/status/1254854971498967041?s=19

The doom/gloom also kind of glosses over that we *do* have vaccines for coronaviruses - for animals! Cows have a particular vaccine for a coronavirus already.

The trouble is that we basically halted development of human coronavirus vaccines because the coronaviruses themselves got stamped away. MERS vaccines were being worked on some years ago, but got cut off when MERS was mostly controlled. In our lifetimes, we've never really had a disease where basically every drat scientist in the world is all working on it at the same time, with near-unlimited funding and the ability to fast-track testing.

There are also new vaccine methods too that we didn't have. They're actively testing the old-fashioned weakened virus injection, but there's also a shitload of genetically reprogrammed options/methods in development. Basically, we should've never stopped fighting SARS/MERS, but it was controlled enough that there was no longer any money in developing a vaccine for it.

Hot Karl Marx
Mar 16, 2009

Politburo regulations about social distancing require to downgrade your Karlmarxing to cold, and sorry about the dnc primaries, please enjoy!
fine, here's some real data and numbers

https://twitter.com/veryimportant/status/1254606547709243392

sharknado slashfic
Jun 24, 2011


Vince :argh:

facialimpediment
Feb 11, 2005

as the world turns
Now y'all have been talking Von Braun to death, but the coronavirus vaccine struggle is going to present an ethical challenge too: testing!

First, you test poo poo on animals and deliberately expose them, that's universally accepted. We're now at the point where vaccines are being shot into people, then those people are turned loose and tracked to see if they get the COVID or not, or develop the antibodies from the vaccine. That's the ethical standard, accepted globally, but that takes a lot of time!

... so what if some country, like China, decides they can't wait that long and decide to run the Rocky Mountain Laboratory trial, but with people? Shoot up a bunch of people with the testing vaccine, give them a few weeks, then deliberately expose them to the coronavirus and forcibly quarantine them. That's WILDLY and HORRIFICALLY unethical here - but I'm sure some rich gently caress could pay some scummy scientists with loose morals to carry out this kind of testing. There might even be volunteers!

So as much as I originally thought the Von Braun talk was just talking about history - that kind of thing could come back shortly! And considering the information lockdown going on in China now and the shady quality of antibody tests, I bet they do it, and I bet some scummy dumbfuck pitches Trump on it at some point.

Edit: or lol we're going to have a second wave and that's a good enough testing ground

https://twitter.com/ndrew_lawrence/status/1254926131570126848

facialimpediment fucked around with this message at 01:54 on Apr 28, 2020

That Works
Jul 22, 2006

Every revolution evaporates and leaves behind only the slime of a new bureaucracy


facialimpediment posted:

Now y'all have been talking Von Braun to death, but the coronavirus vaccine struggle is going to present an ethical challenge too: testing!

First, you test poo poo on animals and deliberately expose them, that's universally accepted. We're now at the point where vaccines are being shot into people, then those people are turned loose and tracked to see if they get the COVID or not, or develop the antibodies from the vaccine. That's the ethical standard, accepted globally, but that takes a lot of time!

... so what if some country, like China, decides they can't wait that long and decide to run the Rocky Mountain Laboratory trial, but with people? Shoot up a bunch of people with the testing vaccine, give them a few weeks, then deliberately expose them to the coronavirus and forcibly quarantine them. That's WILDLY and HORRIFICALLY unethical here - but I'm sure some rich gently caress could pay some scummy scientists with loose morals to carry out this kind of testing. There might even be volunteers!

So as much as I originally thought the Von Braun talk was just talking about history - that kind of thing could come back shortly! And considering the information lockdown going on in China now and the shady quality of antibody tests, I bet they do it, and I bet some scummy dumbfuck pitches Trump on it at some point.

Peter Thiel doing lines off Uighyr "volunteers" in a West China camp.

wins32767
Mar 16, 2007

facialimpediment posted:

First, you test poo poo on animals and deliberately expose them, that's universally accepted. We're now at the point where vaccines are being shot into people, then those people are turned loose and tracked to see if they get the COVID or not, or develop the antibodies from the vaccine. That's the ethical standard, accepted globally, but that takes a lot of time!

... so what if some country, like China, decides they can't wait that long and decide to run the Rocky Mountain Laboratory trial, but with people? Shoot up a bunch of people with the testing vaccine, give them a few weeks, then deliberately expose them to the coronavirus and forcibly quarantine them. That's WILDLY and HORRIFICALLY unethical here - but I'm sure some rich gently caress could pay some scummy scientists with loose morals to carry out this kind of testing. There might even be volunteers!

Why wouldn't there be volunteers? If you reserve some ECMO machines and ICU beds for the folks volunteering, I bet there would be a bunch of folks that'd sign up. You throw in life insurance payments for the folks who don't make it, I'd be having talks with my wife about signing up. The odds are that everyone is going to get it over the next 2 years, why not do it in a controlled way where you're assured of great medical care and you help save lives?

The fact that we aren't doing that shows that we aren't really treating this as seriously as we could be.

CRUSTY MINGE
Mar 30, 2011

Peggy Hill
Foot Connoisseur
It's called the military, you test it on them. We should all know this, the military is pretty much a giant medical trial after "winning" military pissing matches.

Tiny Timbs
Sep 6, 2008

There’s already been volunteers for super experimental vaccines in the US

We’re just not doing the forcible exposure part, though enough trips to the grocery store ought to cover that

M_Gargantua
Oct 16, 2006

STOMP'N ON INTO THE POWERLINES

Exciting Lemon

wins32767 posted:

Why wouldn't there be volunteers? If you reserve some ECMO machines and ICU beds for the folks volunteering, I bet there would be a bunch of folks that'd sign up. You throw in life insurance payments for the folks who don't make it, I'd be having talks with my wife about signing up. The odds are that everyone is going to get it over the next 2 years, why not do it in a controlled way where you're assured of great medical care and you help save lives?

The fact that we aren't doing that shows that we aren't really treating this as seriously as we could be.

capitalism.txt

Milo and POTUS
Sep 3, 2017

I will not shut up about the Mighty Morphin Power Rangers. I talk about them all the time and work them into every conversation I have. I built a shrine in my room for the yellow one who died because sadly no one noticed because she died around 9/11. Wanna see it?

That means Donald didn't do anything to help right

Woofer
Mar 2, 2020

Milo and POTUS posted:

That means Donald didn't do anything to help right

He made it less deadly

wins32767
Mar 16, 2007

M_Gargantua posted:

capitalism.txt

Other than life insurance, does this sort of solution look any different in other system? Sure, maybe there are marginally more ECMO machines in a socialist world, but there isn't enough excess productive capacity to fully ensure against all major societal risks so at some point there will be a crisis that overwhelms normal systems. At that point the fairest solutions are either to ask for volunteers or randomly select people. Regardless of the selection method in either case the right thing to do is provide them adequate support to mitigate the risks they are taking on for the good of everyone else.

I mean, isn't "from each according to their abilities, to each according to their needs" literally communism?

wins32767 fucked around with this message at 03:18 on Apr 28, 2020

Stravag
Jun 7, 2009

Internet Wizard posted:

Oh are you my neighbor

Maybe if you're in North Charlotte.

Amazon put out a text saying they had another confirmed case in this fc, black trump supporter guy walks up to me and goes "they had another here. Supposedly." He also walks around with his mask protecting his neck or in his pocket and doesn't believe it's real or what good masks and gloves are gonna do. Dudes really ...odd. i made a joke about loving white people and he went off about "dont blame white people they get blamed for enough. My best friend is white. Blame the asians and mexicants." I had to glance down to make sure my arms were still white as gently caress cuz it just threw me that hard

Tiny Timbs
Sep 6, 2008

Stravag posted:

he went off about "dont blame white people they get blamed for enough. My best friend is white. Blame the asians and mexicants." I had to glance down to make sure my arms were still white as gently caress cuz it just threw me that hard

That’s an Uncle Ruckus move

Hyrax Attack!
Jan 13, 2009

We demand to be taken seriously

BigDave posted:

Reminds me of the AIDS denial magazine that folded because the entire staff died from AIDS.

https://en.m.wikipedia.org/wiki/Continuum_(magazine)

Hachi machi how have I not heard of this before?!

UP THE BUM NO BABY
Sep 1, 2011

by Hand Knit

wins32767 posted:

I mean, isn't "from each according to their abilities, to each according to their needs" literally communism?

That's socialism

Godholio
Aug 28, 2002

Does a bear split in the woods near Zheleznogorsk?

Ardlen posted:

Poland and the Czech Republic are already in NATO.

So is Turkey.

That Works posted:

It's Bossier, they fly over like that every day lol

Precision nav like flying directly over multiple specific buildings in an urban environment is also useful training for bombers.

This salute is literally simulating a bombing run on every hospital in the area. :lol:

Stravag
Jun 7, 2009

Fallom posted:

That’s an Uncle Ruckus move

In the same 5 minutes he also said blacks and mexicans were trying to fight him at work when he wore his trump hat to work and i think he took my "yeah i can imagine" to mean "wow thats rough" not "yeah i can imagine them being pissed".

bulletsponge13
Apr 28, 2010

2020 delivering like door dash.

https://twitter.com/GovJVentura/status/1254783039642595330?s=20

gently caress yeah, let's burn it down. Back to back WWE champs for Pres!

Vincent Van Goatse
Nov 8, 2006

Enjoy every sandwich.

Smellrose

facialimpediment posted:

That's the doom/gloom version of this:

https://twitter.com/dandrezner/status/1254854971498967041?s=19

The doom/gloom also kind of glosses over that we *do* have vaccines for coronaviruses - for animals! Cows have a particular vaccine for a coronavirus already.

The trouble is that we basically halted development of human coronavirus vaccines because the coronaviruses themselves got stamped away. MERS vaccines were being worked on some years ago, but got cut off when MERS was mostly controlled. In our lifetimes, we've never really had a disease where basically every drat scientist in the world is all working on it at the same time, with near-unlimited funding and the ability to fast-track testing.

There are also new vaccine methods too that we didn't have. They're actively testing the old-fashioned weakened virus injection, but there's also a shitload of genetically reprogrammed options/methods in development. Basically, we should've never stopped fighting SARS/MERS, but it was controlled enough that there was no longer any money in developing a vaccine for it.

Drug discovery chemist and hellish chemical enthusiast Derek Lowe has a few longform blog posts laying out the state of play for vaccine development that I recommend reading if you want actual informed analysis of what's happening.

Godholio
Aug 28, 2002

Does a bear split in the woods near Zheleznogorsk?
Ventura doesn't have a history of sexual harrassment/abuse/rape allegations, right?

Crab Dad
Dec 28, 2002

behold i have tempered and refined thee, but not as silver; as CRAB


Well... wasn’t he a SEAL precursor?

hobbesmaster
Jan 28, 2008

LingcodKilla posted:

Well... wasn’t he a SEAL precursor?

He completed BUDS which means he did combat diving and not all the counter terrorism stuff that seal team six/DEVGRU got tasked with after operation eagle claw went horribly wrong.

So that’s normal navy odds right?

facialimpediment
Feb 11, 2005

as the world turns

Vincent Van Goatse posted:

Drug discovery chemist and hellish chemical enthusiast Derek Lowe has a few longform blog posts laying out the state of play for vaccine development that I recommend reading if you want actual informed analysis of what's happening.

Holy loving balls we are throwing everything at this thing in vaccine form:

quote:

Summary

So by my count, the biggest and most advanced programs include two inactivated virus vaccines, three different adenovirus vector vaccines, two mRNA possibilities, a DNA vaccine, and a recombinant protein. That’s a pretty good spread of mechanisms, and there are of course plenty more coming up right behind these. You cannot do the tiniest search for such information without being inundated with press releases about companies working on coronavirus vaccines – not complaining here – and moving on to smaller companies would make this post multiple times longer. I’ll update as more news comes out and add in more companies and candidates.

That's a good drat link that I need to spend some time with.

maffew buildings
Apr 29, 2009

too dumb to be probated; not too dumb to be autobanned

hobbesmaster posted:

He completed BUDS which means he did combat diving and not all the counter terrorism stuff that seal team six/DEVGRU got tasked with after operation eagle claw went horribly wrong.

So that’s normal navy odds right?

Yeah dude is an Underwater Demolition Team frogman which makes the whole claiming the SEAL thing weird because uh, that UDT poo poo seems like it would have been plenty rough. Anyway 50/50 on rapist, yes.

The Sausages
Sep 30, 2012

What do you want to do? Who do you want to be?

CRUSTY MINGE posted:

It's called the military, you test it on them. We should all know this, the military is pretty much a giant medical trial after "winning" military pissing matches.

:australia:

ABC posted:

ADF personnel should not be used as 'guinea pigs' in coronavirus drug trial, former Army doctor says

Health professionals and Army veterans fear military personnel may be "used as guinea pigs" in a drug trial conducted by the Australian Defence Force (ADF) to find a medicine that will help fight COVID-19.

Ethical approval to carry out a clinical trial of the anti-malaria drug chloroquine was granted to the ADF's Malaria and Infectious Diseases Institute on Wednesday last week.

It will test whether chloroquine is effective in stopping people from contracting coronavirus.

An email sent by ADF surgeon general Sarah Sharkey and obtained by the ABC's PM program said the trial would involve military personnel and frontline civilian healthcare workers who volunteered to take part.

"Well controlled trials are urgently needed given the profound global impacts of this disease," the email states.

Veterans involved in previous drug trials speak out
Major Stuart McCarthy, who was given the anti-malarial drug tafenoquine during a different trial conducted in the early 2000s, said he had serious concerns about the COVID-19 research.

"One of my primary concerns with these proposed trials is that there will be a degree of coercion placed on exactly the people who will be at the front line of our response to the COVID-19 pandemic," Major McCarthy said.

He said participants in past trials were pressured into taking part and felt unable to report side effects.

"That then has a flow-on effect when those reports are published, that then distorts the safety of those drugs as they enter the civilian market," he said

International guidelines for good clinical practice identify members of the armed forces as vulnerable subjects for medical research because they may feel an expectation to participate.

Steven Scally, a former Australian Army medical officer and practising GP with an interest in veteran health, said the ADF had a "poor track record" of conducting medical research.

"I wouldn't even be confident seeing them conduct trials on Panadol to be quite honest," Dr Scally said.

"We are nowhere near getting to the bottom of what's happened with trials that were conducted many years ago, so I just don't think the Australian Defence Force has an established reputation at all for conducting any sort of medical research at all."

Recommendations on using Defence personnel in drug trials
In 2018, a Senate inquiry handed down its report into the mefloquine and tafenoquine trials conducted by the ADF in the late 1990s and early 2000s.

Veterans involved in the trials told the inquiry they continued to experience long-term side effects linked to the anti-malaria drugs, including psychosis, anxiety, depression and memory loss.

"Many of those individuals continue to beg to charity for medical care, some of them are homeless and sadly many of them have suicided," Major McCarthy said.

The Department responded to the inquiry by announcing a $2.1 million to provide comprehensive health assessments for those involved in the trials over four years.

It also agreed to the recommendation that the Defence and Veterans' Affairs Human Research Ethics Committee change its terms of reference to consider that research participants may be vulnerable to perceived coercion to participate in trials.

The same committee approved the COVID-19 trial on Wednesday.

An ADF spokesperson said it was part of the whole-of-Government response to the COVID-19 pandemic, and the trial would be subject to rules provided by the Therapeutic Goods Administration, including obtaining informed consent.

But Dr Scally said he did not believe that was possible.

"Consent and volunteerism is a redundant concept in the military," he said.

"Pretty much at the time of enlistment, upon taking the oath, you exchange free will for obedience and that is a culture that really has to exist for the purpose of carrying out your role as a soldier or a sailor or an airman to defend the country."

He said serving members of the defence force should not be subjected to further potential harm by participating in medical research.

"I don't think it's the role of the ADF to offer up its personnel and human resources to be used as guinea pigs for a drug trial," he said.

Some in favour of urgently needed trials
The ADF did not responded to a series of questions from the ABC about suggestions of ongoing health issues in time for publication.

In the email obtained by the ABC, the ADF surgeon general said the safety profile of chloroquine as an anti-malaria drug was well understood from its use in over a billion people.

She said despite the similar sounding name, it did not share the same adverse events as mefloquine.

Others have also spoken in favour of the COVID-19 trial, saying medical research into coronavirus prevention is urgently needed.

The CSIRO's health and biosecurity health director Rob Grenfell said he was confident the study would be well designed.

"Australia has very tight and stringent and some of the highest order of trial-conducted studies," Dr Grenfell said.

BIG HEADLINE
Jun 13, 2006

"Stand back, Ottawan ruffian, or face my lumens!"

bulletsponge13 posted:

2020 delivering like door dash.

https://twitter.com/GovJVentura/status/1254783039642595330?s=20

gently caress yeah, let's burn it down. Back to back WWE champs for Pres!

:sigh:

Just what we need, potential spoiler candidates in another election that'll come down to single-digit percentage point differences in key states. I loathe Biden, but he's the steaming bowl of poo poo that isn't Trump.

Crazy Mike
Sep 16, 2005

Now with 25% more kimchee.

bulletsponge13 posted:

2020 delivering like door dash.

https://twitter.com/GovJVentura/status/1254783039642595330?s=20

gently caress yeah, let's burn it down. Back to back WWE champs for Pres!

:actually: Back to back WWE Hall of Famers. :eng101:

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bulletsponge13
Apr 28, 2010

Crazy Mike posted:

:actually: Back to back WWE Hall of Famers. :eng101:

I couldn't remember if Ventura was in the HoF or not, considering his issues with Vince in the past.

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