code:

(for chrome)
1. Load the page
2. Locate evolve.js in the devconsole
3. Place a breakpoint at line 4: switch (data.loop) {
4. Reload the page
5. Hover over 'data' and change 'period:' to 25 (lowest I found that still works and doesn't lockup the game after a while)
6. Click resume script execution, or press F8
7. Repeat step 5 and 6 two more times for each type of loop (main, which handles the evolution stage, mid, which handles mostly everything else, and long, which handles the day cycles and some other stuff)

You'll have to repeat this every time you prestige. Or make a tampermonkey/greasemonkey script to do it for you.

Some tips for optimizing:
-Set the short speed as low as 20 up through Bioseeding for maximum speed e.g. 20/1000/5000
-Set the long speed as low as 100 for maximum soul gem farming e.g. 250/1000/100
-Set the mid speed as low as 50 for mech grinding e.g. - 250/50/5000
-Messing with all of the speeds at once will make the game chug anywhere past the early game, so setting the above speeds when you need to will maximize your output

Basically you don't need to mess with the different loops outside of the one you're currently utilizing most. Short for resource farming. Mid for mechs and spying. Long for day cycle, so pretty much just soul gems.