Lynneth posted:

We live in the cyberpunk world. It's just the shittiest, most boring and least neon-coloured one.

habeasdorkus posted:

This has been my take for about a decade and a half. We live in the most boring cyberpunk dystopia.

I dont know posted:

All the corporate greed and government oppression. None of the cool cyberware or robodongs.

Lynneth posted:

We live in the cyberpunk world. It's just the shittiest, most boring and least neon-coloured one.

I dont know posted:

All the corporate greed and government oppression. None of the cool cyberware or robodongs.

SIGSEGV posted:

We don't have the cool cyberware, but we have the nightmarish body horror societal / legal interaction cyberware failures:

https://twitter.com/msbellows/status/1493657979140276225

https://spectrum.ieee.org/bionic-eye-obsolete

Boat Stuck posted:

Wow that could be a quest straight from this game. Truly, the (poo poo) future is now.

dervival posted:

Yeah. Cyberpunk is here, and we are not the runners. I'm just glad we don't have sovereign corporate nations as a standard quite yet.

achtungnight posted:

Speak for yourself. I got a Johnson on speed dial, a drone controlled via my cyber arm, and a team looking for a decker*.

* Must be competent, not use combat stims, able to operate a moped, willing to speak up loudly when the team is in danger and he doesn’t have a turret under control.

JT Jag posted:

My dad just bought me a Fairlight Excalibur, does that work

achtungnight posted:

Can you use it? Hack the Ares mainframe, make it look like Lofwyr was responsible, plant data that will lead them to Aztechnology’s latest scheme regarding insect spirits and blood magic, then we’ll talk.

JT Jag posted:

I edited the company logo on the Ares intranet to be a dickbutt guy wearing the helmet and it took their resident deckers five whole minutes to revert it back, does that count

habeasdorkus posted:

If any of you start a poetry slam, God as my witness I will turn you all in.

apostateCourier posted:

to who, chummer?

apostateCourier posted:

to who, chummer?

wiegieman posted:

Grid
Overwatch
Division

wiegieman posted:

Grid
Overwatch
Division

apostateCourier posted:

to who, chummer?

Kanfy posted:

Quackles posted:

Quiet in the thread
Then we host a poem-off
Hey, it's your move,

biosterous posted:

in the meantime anyone who needs a shadowrun fix can read (or reread) blake island school of magic

biosterous posted:

in the meantime anyone who needs a shadowrun fix can read (or reread) blake island school of magic

bob dobbs is dead posted:

the worlds going to poo poo its ok

Lynneth posted:

We live in the cyberpunk world. It's just the shittiest, most boring and least neon-coloured one.

biosterous posted:

in the meantime anyone who needs a shadowrun fix can read (or reread) blake island school of magic

StillFullyTerrible posted:

i really really loved that thread until the OP wrote some absolutely unhinged stuff about covid elsewhere on the forums, kinda ruined it for me.

Ice Phisherman posted:

I’m legit worried about going into my old posts about covid due to how insane I was. The world was insane and growing worse. I tried to help as many people as I could. I fought against the most sophisticated media machine on the planet and people straight up not understanding what plague and quarantine and what that meant. I Reached my limit multiple times, pushed past them and then kept going despite what my friends, family and my own body we’re telling me.

Then I stopped, adapted, I chilled out and I’m no longer having extreme stress reactions like my throat closing up or my heart hammering like it’s trying to explode out of my back. I barely even wake up screaming once a month these days. Completely serious. That level of stress nightmare is no joke.

I’d like to do a self care mega post at some point about how one mentally adapts and overcomes trauma, but honestly a lot of it is playing Mario Kart 8 and Borderlands 2. Just straight abnegation. Logging off, basically. Along with enjoying a new relationship and indulging in creative pursuits.

I probably need a lot of therapy though. Like a lot. But in the meantime, I don’t have that many nightmares anymore and I had a really chill dream about cuddling a duck. The most BYOB dream ever.

What I’m saying and what I’ll keep saying is that while I love this thread as a resource, it’s okay to step away if you’re not feeling good. Most of us already understand how to adapt. Mask up, vaxx up, don’t breathe the unfiltered air of people you don’t trust. That’s it really. Not everyone can do this. I understand being able to do that is a privilege and for those that can’t, I’m sorry. But if you can you should. It protects yourself and others.

You’ve got 99% of how to deal with covid. So if you need to step back because poo poo is getting overwhelming, maybe you should.

quote:

With a $2.1 Million Cure Their Only Hope, Parents Plead for Help Online

India makes many of the world’s drugs, but treatments for rare diseases like spinal muscular atrophy are imported and prohibitively costly. In desperation, parents are raising funds on social media.
April 6, 2022


ELURU, India — When her baby started struggling to breathe, Stella Praveen had a terrible feeling that something was gravely wrong with her 14-month-old daughter, Ellen.

She ran barefoot to a nearby clinic, but the doctors there said the child needed to see a specialist right away. Without an ambulance, she jumped on the back of a motorcycle and rode 35 miles to a children’s hospital in another town, where Ellen remained in intensive care for 12 days.

Two weeks later, Ms. Praveen learned that her daughter, who had never been able to lift her neck nor roll over, was suffering from spinal muscular atrophy, a rare condition often fatal by age 2.

“We had not even heard of this disease,” Ms. Praveen said as tears rolled down her face. “She was misdiagnosed many times.”

The Praveen family was momentarily heartened when it learned that a promising gene therapy treatment was available, but was quickly crestfallen when it heard the cost: $2.1 million.

In India, and in many of the world’s poorer countries, the pharmaceutical industry’s latest advances for rare diseases are often agonizingly out of reach, impossible for almost all but the wealthiest families to afford and not covered by health insurance.

In desperation — and encouraged by the occasional success story — families are turning to social media to raise funds.

Every morning, Ellen’s father, Rayapudi Praveen, sends hundreds of emails on five crowdfunding websites like ImpactGuru and GoFundMe, asking people to contribute money to save his daughter’s life.

“Dear Sir, my daughter Ellen is suffering,” every email begins. “Can you help us?”

With only four months left before Ellen turns 2, time is running out — and the family is still far from its goal.

quote:

In December 2019, Novartis announced that it would donate 100 doses of onasemnogene abeparvovec per year to children outside the US through a global lottery. The decision, which has been claimed by Novartis to be based on a recommendation by unnamed bioethicists,[39] was received with much criticism by the European Commission,[40] some European healthcare regulators[41] and patient groups (e.g., SMA Europe or the UK's TreatSMA) who see it as emotionally burdening, suboptimal, and ethically questionable.[42] Novartis did not consult with families or doctors before announcing the scheme.[43][44] Alan Regenberg, a bioethicist at Johns Hopkins Berman Institute of Bioethics, said that the scheme was perhaps the best available since it may be impossible to reliably establish prognosis for children under two years of age.[39]

quote:

After over two years of testing, Glybera was approved in the European Union in 2012. However, after spending millions of euros on Glybera's approval, AMT went bankrupt and its assets were acquired by uniQure.

Alipogene tiparvovec was expected to cost around $1.6 million per treatment in 2012 - revised to $1 million in 2015 - making it the most expensive medicine in the world at the time. However, replacement therapy, a similar treatment, can cost over $300,000 per year, for life.

In 2015, uniQure dropped its plans for approval in the US and exclusively licensed rights to sell the drug in Europe to Chiesi Farmaceutici for €31 million.

As of 2016, only one person had received the drug outside of a clinical trial.

In April 2017, Chiesi quit selling Glybera and uniQure announced that it would not pursue the renewal of the marketing authorisation in the European Union when it was scheduled to expire that October, due to lack of demand. Afterwards, the three remaining doses in Chiesi's inventory were administered to three patients for €1 each.

Quackles posted:

Quiet in the thread
Then we host a poem-off
Hey, it's your move,