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https://twitter.com/JohnWFerguson/status/1611780615883587585?s=20&t=iDYc2Mqejev0Kxnoq-S4PQ I actually forgot about this happening.
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Jan 8, 2023 03:39
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Assault with a deadly weapon?!? Did the DA try to claim it was literally a claw?
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Jan 8, 2023 04:15
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The charges were dropped when they learned it was a White Claw.
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Jan 8, 2023 04:18
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Tayter Swift posted:Assault with a deadly weapon?!? Did the DA try to claim it was literally a claw? He threw the cans at Cruz's rear end so hard the cans were considered deadly weapons. Impressive.
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Jan 8, 2023 04:19
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rear end Assault w/deadly Weapon by Chuck Tingle
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Jan 8, 2023 04:20
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If it had been a Four Loko the cops would have shot him.
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Jan 8, 2023 04:38
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White claws, for my family
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Jan 8, 2023 06:01
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Texas has spoken. It's your god given right and duty to make sure Ted Cruz is hydrated by tossing him can after can of cheep alcohol. Overhand only.
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Jan 8, 2023 06:11
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I don't think it's actually been mentioned here yet, but Kevin McCarthy is now Speaker of the House, on the 15th attempt
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Jan 8, 2023 06:48
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haveblue posted:I don't think it's actually been mentioned here yet, but Kevin McCarthy is now Speaker of the House, on the 15th attempt Prove it 
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Jan 8, 2023 07:33
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Your honor, my client was under the impression that there ain't no laws when you're drinking claws.
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Jan 8, 2023 07:42
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BIG FLUFFY DOG posted:I thought this was also the hand signal for rear end in a top hat in Brazil It is.
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Jan 8, 2023 10:49
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Angry_Ed posted:
Character actor Nelson Franklin's agent must be creaming themselves for the eventual biopic when this guy ends up self-immolating.
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Jan 8, 2023 14:03
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bobjr posted:https://twitter.com/JohnWFerguson/status/1611780615883587585?s=20&t=iDYc2Mqejev0Kxnoq-S4PQ
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Jan 8, 2023 14:13
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haveblue posted:I don't think it's actually been mentioned here yet, but Kevin McCarthy is now Speaker of the House, on the 15th attempt
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Jan 8, 2023 18:08
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I knew that the fentanyl crisis was bad but I didn't know that it had added a horrible spin: the veterinary tranquilizer xylazine. I feel like our country is on fire and instead of firemen all we get are more arsonists. https://www.yahoo.com/news/tranq-dope-animal-sedative-mixed-152242327.html quote:PHILADELPHIA — Over a matter of weeks, Tracey McCann watched in horror as the bruises she was accustomed to getting from injecting fentanyl began hardening into an armor of crusty, blackened tissue. Something must have gotten into the supply. quote:A study published in June detected xylazine in the drug supply in 36 states and the District of Columbia. In New York City, xylazine has been found in 25% of drug samples, although health officials say the actual saturation is certainly greater. In November, the Food and Drug Administration issued a nationwide four-page xylazine alert to clinicians. quote:Brooke Peder, a 38-year-old tattoo artist nicknamed the Hood Grandma, rolled her wheelchair to the exchange check-in and handed over a gallon container filled with syringes. Her mother, sister and wife died of overdoses. Just over a year ago, her right leg had to be amputated because of an infection from a tranq wound that bore into the bone. quote:One day in August, she caught a glimpse of herself: Normally weighing 150 pounds, she was down to 90. “I thought, I either need to do a lethal shot of xylazine or get the hell out of Kensington,” she said.
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Jan 8, 2023 18:09
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Christ...that sounds similar to the Russian drug krokodil which causes those really nasty wounds
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Jan 8, 2023 18:14
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The opioid problem is one that we could solve any day we wanted with the right application of money since its roots are in the homelessness and poverty problems, we just choose not to. FlamingLiberal posted:Christ...that sounds similar to the Russian drug krokodil which causes those really nasty wounds Krokodil was most likely desomorphine.
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Jan 8, 2023 18:24
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Tayter Swift posted:rear end Assault w/deadly Weapon Pounded in the Butt by White Claw While Pounding White Claw
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Jan 8, 2023 19:22
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Gumball Gumption posted:The opioid problem is one that we could solve any day we wanted with the right application of money since its roots are in the homelessness and poverty problems, we just choose not to. The opioid problems roots is pharmaceutical companies basically bribing doctors to prescribe as often as possible and Florida having basically no rules for prescriptions for a good decade.
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Jan 8, 2023 19:33
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FlamingLiberal posted:Christ...that sounds similar to the Russian drug krokodil which causes those really nasty wounds Looking at the pharmacology of xylazine, because I was wondering how it was causing the eschars, but it looks like it's a cascading effect from the drug's primary: it causes a brief bout of hypertension (high blood pressure) followed by a combination of hypotension (low BP), bradycardia (lowered heart rate), and respiratory depression, which reduces oxygenation of blood and skin, which impairs the healing process. And if some injecting this into the same location constantly, it's aggravating the injection site wound to the point it gets to where it gets necrotizing. Also, it's not covered in the article excerpt, but the pharmacokinetics has been known to cause type 2 diabetes and hyperglycemia, which also impair healing process. Gumball Gumption posted:Krokodil was most likely desomorphine. Yeah, the issue with krokodil and it's disfiguring side-effects had less to do with the drug itself more to do with the purification process: the Russians making this weren't using particularly cautious to what they used separate the codeine from over-the-counter cough medicine, using such particularly healthy chemicals like battery acid and paint thinner, or using excessive quantities of lye or hydrochloric acid, which spiked the pH levels. All of this lead to a perfect storm of toxicity.
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Jan 8, 2023 19:40
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Young Freud posted:Looking at the pharmacology of xylazine, because I was wondering how it was causing the eschars, but it looks like it's a cascading effect from the drug's primary: it causes a brief bout of hypertension (high blood pressure) followed by a combination of hypotension (low BP), bradycardia (lowered heart rate), and respiratory depression, which reduces oxygenation of blood and skin, which impairs the healing process. And if some injecting this into the same location constantly, it's aggravating the injection site wound to the point it gets to where it gets necrotizing. Also, it's not covered in the article excerpt, but the pharmacokinetics has been known to cause type 2 diabetes and hyperglycemia, which also impair healing process. Yeah, I got curious and found this https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9482722/ which suggests what you're saying, it's damaging the skin and it's not able to fight off infection. BIG FLUFFY DOG posted:The opioid problems roots is pharmaceutical companies basically bribing doctors to prescribe as often as possible and Florida having basically no rules for prescriptions for a good decade. Well yes, that too. That's also a problem we could have solved for a long time and didn't because it was profitable enough that there was opposition to fixing it.
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Jan 8, 2023 21:07
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BIG FLUFFY DOG posted:The opioid problems roots is pharmaceutical companies basically bribing doctors to prescribe as often as possible and Florida having basically no rules for prescriptions for a good decade. this would not be an issue if there was not a huge amount of people desperate to anesthetize themselves against the intolerable conditions of poverty, loneliness, etc. that they are in at other times in history access to the hard stuff has been much, much easier and not resulted in this magnitude of death
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Jan 8, 2023 21:12
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I mean we're still not really stopping anything with the opioid epidemic As far as I can tell it's a combination of blame China for fentanyl, arrest addicts, and then just shrug. The biggest 'win' was that Perdue Pharmaceuticals had to mostly shut down, but they paid a pretty paltry fine and the family in control of the company isn't really facing much in the way of consequences. As far as I can tell, there really isn't anything stopping another company from just doing the same poo poo again, since in the big HBO doc about the opioid crisis, they talked for awhile about how there is so much regulatory capture of the FDA by the pharmaceutical industry that if a company does shady poo poo like this again, they'll just offer the FDA regulators like 10x what they make to become Pharma lobbyists to prevent any real consequences.
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Jan 8, 2023 21:44
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Gumball Gumption posted:Yeah, I got curious and found this https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9482722/ which suggests what you're saying, it's damaging the skin and it's not able to fight off infection. It supposedly used as an emergency treatment for tetanus, so it's meant to be used sparingly. If you're using it chronically, it'll just compound the damage done. The weird thing I found is that the overdose dosage for xylazine was between 40mg-2400mg, just a loving huge range. No wonder the FDA never accepted it for human use.
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Jan 8, 2023 21:52
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HookedOnChthonics posted:this would not be an issue if there was not a huge amount of people desperate to anesthetize themselves against the intolerable conditions of poverty, loneliness, etc. that they are in I thought the opioid epidemic was a consequence of pharmaceutical companies incentivizing doctors to heavily overprescribe highly addictive drugs with insufficient caution or controls, driving many patients to become addicted and continue to seek the drugs afterward. Portraying it as "people desperate to anesthetize themselves against the intolerable conditions of poverty" is, I think, incredibly uncharitable at best. It looks sympathetic at first glance, but it's really just a slight reframing of War On Drugs narratives on addiction: it's based on the idea that drug addiction is simply a result of poor people lacking willpower and driving themselves to death to escape their unhappiness, rather than a physical dependence. Though of course, those kinds of narratives long predate the War On Drugs - it's long been convenient for the elites selling the drugs to suggest that addiction is just poor people becoming obsessed.
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Jan 8, 2023 22:10
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Young Freud posted:The weird thing I found is that the overdose dosage for xylazine was between 40mg-2400mg, just a loving huge range. No wonder the FDA never accepted it for human use. For horses, dogs, and cats, it's 0.5-1mg/kg IV for sedation.
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Jan 8, 2023 22:11
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Main Paineframe posted:I thought the opioid epidemic was a consequence of pharmaceutical companies incentivizing doctors to heavily overprescribe highly addictive drugs with insufficient caution or controls, driving many patients to become addicted and continue to seek the drugs afterward. Pretty sure it's a little bit of both. Capitalism creates the material conditions that drive people to seek relief from them, and capitalism also pushes a terrible solution on them. That's not the same as saying it's their fault for not being strong enough.
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Jan 8, 2023 22:39
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Fister Roboto posted:Pretty sure it's a little bit of both. Capitalism creates the material conditions that drive people to seek relief from them, and capitalism also pushes a terrible solution on them. That's not the same as saying it's their fault for not being strong enough. This requires you to believe that the rich and comfortable aren't eager to go and get high. The real answer is that the many rich people who become addicts have the resources to get out of crippling addictions, or at least not be driven down to getting a fix from something that leads to rotting your limbs off.
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Jan 8, 2023 23:15
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Fister Roboto posted:Pretty sure it's a little bit of both. Capitalism creates the material conditions that drive people to seek relief from them, and capitalism also pushes a terrible solution on them. That's not the same as saying it's their fault for not being strong enough. This is completely missing the entire point of the post that sparked this conversation (that hard drugs were far more freely available in the past but we did not see widespread addiction) in order to make some nebulous point about everything bad coming from capitalism. It also assumes rich happy people don't do drugs. HookedOnChthonics posted:at other times in history access to the hard stuff has been much, much easier and not resulted in this magnitude of death I am not sure this is true, it confuses legality with ease of access. You could buy medicine with heroin or cocaine in it over the counter in the past, but those drugs are still available, it's just illegal. If you're referring to fentanyl deaths, I'm not sure a drug that is lethal in such small dosages has ever been widely available.
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Jan 8, 2023 23:20
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Although it wouldn't change the behavior of the people with power I don't think that they truly comprehend the horrors they've unleashed and perpetuate. The everyday horrors playing out in every city and town from coast to coast as human lives are essentially tossed into a blender and liquified before being poured down the drain.
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Jan 8, 2023 23:36
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Killer robot posted:This requires you to believe that the rich and comfortable aren't eager to go and get high. The real answer is that the many rich people who become addicts have the resources to get out of crippling addictions, or at least not be driven down to getting a fix from something that leads to rotting your limbs off. Bourgeoisie drug use being inherently different in make-up and consequence-free when compared to the drugs available to the working class is not an argument against Capitalism being the source of the societal problem.
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Jan 8, 2023 23:47
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A significant factor in this process is a series of cases, including principally Washington Legal Foundation v. Henney, which effectively ruined the FDA's ability to exert tight control over physician prescribing practices for drugs, facilitating the programmatic (and now incredibly difficult to reverse) proliferation of off-label use. FDA's legal divisions are basically paralyzed in many offlabel drug marketing contexts because of these precedents. The Washington Legal Foundation is basically one of the most harmful actors in DC- they're very effective at bringing well-targeted test cases intended to force deregulatory precedent, and they're sophisticated enough to plan for additional actions based on different possible case outcomes. Offlabeling has been the preferred target for industry because while FDA's CDER has capture problems (ones that will be made much worse by the pandemic, see e.g. the Aduhelm mess), capturing an agency can only go so far, and it's expensive and can set different industry groups against each other (some parts of industry benefit from regulations, depending on the circumstances). Capturing physicians through sales and influence is much cheaper, and direct marketing and comms from industry is something they would have to do anyway to market their products. Training seminars and incredibly inexpensive branded gifts and low-quality research are all easier to target to physicians, who are self-regulated through state boards. Discendo Vox fucked around with this message at 00:56 on Jan 9, 2023 |
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Jan 9, 2023 00:11
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FlamingLiberal posted:I mean we're still not really stopping anything with the opioid epidemic "Hilarious" personal anecdote: my mom's doctor had been prescribing her Tramadol with the exact same "it's not addictive!" spiel that doctors had been saying about Oxycotin, until he suddenly decided she didn't need to be on it anymore. Soon after I saw some stories about people with Tramadol addictions. 
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Jan 9, 2023 00:49
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Killer robot posted:This requires you to believe that the rich and comfortable aren't eager to go and get high. The real answer is that the many rich people who become addicts have the resources to get out of crippling addictions, or at least not be driven down to getting a fix from something that leads to rotting your limbs off. DeadlyMuffin posted:This is completely missing the entire point of the post that sparked this conversation (that hard drugs were far more freely available in the past but we did not see widespread addiction) in order to make some nebulous point about everything bad coming from capitalism. I'm genuinely confused why both of you think I'm making this assumption. I didn't say that this was the only reason that anyone uses drugs. Yes, obviously the rich are able to do drugs recreationally with not a lot of negative consequences to their health or social status. I didn't say otherwise. And yes this may come as a surprise, but capitalism - the inescapable system that we all live in - does indeed cause a lot of problems. I didn't say that everything bad is caused by it, so that's a pretty extreme mischaracterization of my post.
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Jan 9, 2023 02:02
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DeadlyMuffin posted:This is completely missing the entire point of the post that sparked this conversation (that hard drugs were far more freely available in the past but we did not see widespread addiction) in order to make some nebulous point about everything bad coming from capitalism. It all started in response to my post and lmao capitalism is absolutely the problem. Wealth decides if your drug problem is life destroying or a fun but kind of dangerous hobby. It's not the rich opioid addicts using stuff that's been cut with vet meds. Gumball Gumption fucked around with this message at 02:27 on Jan 9, 2023 |
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Jan 9, 2023 02:24
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Fister Roboto posted:Pretty sure it's a little bit of both. Capitalism creates the material conditions that drive people to seek relief from them, and capitalism also pushes a terrible solution on them. That's not the same as saying it's their fault for not being strong enough. In the case of the opioid epidemic, it wasn't that people were seeking relief from "the material conditions of capitalism", it's that they were seeking relief from things like injuries or post-surgical pain. Their doctor prescribed oxycontin or something as a routine painkiller, and they got addicted. To repeat myself, it's actually bad to describe drug addiction as poor people taking drugs because they're unhappy. Even if you're trying to blame the reasons they're unhappy, it's still a narrative that treats addiction as a choice rather than as a condition. And that's especially crappy when it comes to the opioid crisis, which was created by unscrupulous pharmaceutical companies deceiving doctors into prescribing highly addictive substances for legitimate medical reasons. Gumball Gumption said earlier that the roots of the opioid epidemic were in homelessness and poverty, but that's mixing up cause and effect. It's certainly true that there's a lot of homeless opioid addicts. But they didn't start using drugs because they were homeless - rather, they became homeless because they were addicted to drugs. Substance abuse disorders are expensive, and tend to destroy a person's financial health as well as their physical health.
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Jan 9, 2023 03:31
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Gumball Gumption posted:It all started in response to my post and lmao capitalism is absolutely the problem. Wealth decides if your drug problem is life destroying or a fun but kind of dangerous hobby. It's not the rich opioid addicts using stuff that's been cut with vet meds. Yah those people who on a whim got prescribed an opioid after their dental surgery. The capitalism criticism goes to the after stuff with opioids, not so much the before in this case.
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Jan 9, 2023 03:39
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MP is mostly right there. A lot of people end up in poverty with opioid addictions because our healthcare system sucks and they're trying to self medicate for pain issues, injuries, psych issues, etc, and they can't afford or get coverage. But they can get opioids, which they already may have received a small amount of thanks to the Pharma industry pushing doctors to prescribe it for anything. While some people may get into drugs as a self medication for the pain of *being* poor, a lot of the times it's the cause of being poor and homeless. The main difference between poor addicts and wealthy ones is that the wealthy ones weren't driven into poverty by their addictions, because they were wealthy.
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Jan 9, 2023 03:53
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Main Paineframe posted:Gumball Gumption said earlier that the roots of the opioid epidemic were in homelessness and poverty, but that's mixing up cause and effect. It's certainly true that there's a lot of homeless opioid addicts. But they didn't start using drugs because they were homeless - rather, they became homeless because they were addicted to drugs. I generally feel like it runs both ways. Economic desperation is incredibly stressful and mentally toxic to most people, no matter how mentally 'strong,' and it creates the conditions for people to ease into substance abuse disorders just to try to get back any semblance of pleasure in their lives, especially when their families are running pretty close to the waterline.
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Jan 9, 2023 03:55
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