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Leon Trotsky 2012 posted:Medicare is considering adding new diabetes and weight loss drugs Ozempic, Mounjaro, and Wegovy to their covered drug list. These drugs were originally for diabetes treatment, but they discovered that they seemed to be the first significantly effective weight loss drug and they have since been used off-label for weight loss. Two of them were eventually approved for weight loss in certain extreme cases in 2022. Using the drugs results in between 15% and 22% reduction in body weight over a year. for folks like me who had never heard of this class of drugs and were wondering about the mechanism of action, after a bit of brief skimming of relevant articles, it appears that the same mechanism that regulates insulin levels is also an effective appetite suppressant. it'd be nice to have a tool to help folks deal with the clash between a body designed for calorie scarcity and a commercial food sector incentivized to maximize that innate drive
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Apr 24, 2023 19:37
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Hieronymous Alloy posted:Might still result in an overall cost savings given how harmful obesity is generally. The Institute for Clinical and Economic Review, which is an org that Medicare frequently uses for outside cost-effectiveness studies, recently determined that Wegovy had a cost of about $237,000 per quality-adjusted life-year for the average person when taken exclusively for weight loss. They consider about $100,000 per quality-adjusted life-year for a drug to be considered cost-effective for the average person and nothing above $150,000 per quality-adjusted life-year can be considered cost-effective. That means that the drugs are currently almost 2.5x higher than the "normal" definition of cost-effective and still about 50% higher than even the maximum threshold. They determined that semaglutide was by far the most effective weight loss drug they tested, but was also the second least cost-effective. quote:Phentermine/topiramate and bupropion/naltrexone both meet commonly accepted cost-effectiveness thresholds when compared to lifestyle modification alone; both of these combination therapies are cost-saving when prescribed generically. When used for weight loss among patients with obesity (and not treatment of diabetes), semaglutide does not meet typical cost-effectiveness thresholds at its current estimated net price, but it is more effective, less burdensome, and more cost effective than liraglutide. https://icer.org/news-insights/press-releases/icer-publishes-evidence-report-on-treatments-for-obesity-management/ Leon Trotsky 2012 fucked around with this message at 19:39 on Apr 24, 2023 |
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Apr 24, 2023 19:37
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Charliegrs posted:I think both are very likely. All of the various texts and emails that were dug up during the Dominian hearings, I could see some really problematic communications between Tucker and Russian agents being unearthed. His narratives on the Ukraine war this last year have been literally the same as Russian propaganda channels. I doubt he came up with that all on his own. They finally figured out what goes into those Swanson TV dinners
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Apr 24, 2023 19:38
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Hieronymous Alloy posted:Might still result in an overall cost savings given how harmful obesity is generally. Given that you have to stay on it for it to remain effective and the instant you stop taking it you start gaining the weight back? I'm gonna say probably not.
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Apr 24, 2023 19:44
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Leon Trotsky 2012 posted:Under current law, Medicare does not cover any drugs for weight loss. The makers of the drugs are lobbying to change the law and allow drugs that are being prescribed for weight loss alone to be covered. However, given that the drugs are very new and very expensive, if 10% of Medicare patients who are obese or overweight began taking the drug (the estimated uptake percentage), then it could cost around $27 billion per year. That is equivalent to about 18.5% of all current Medicare drug spending. Alternatively, Congress could pass drug-price controls for Medicare beyond insulin & the handful of chemo drugs they might regulate at 2026 pricing. In fact, the debt-ceiling deadline would appear to be a wonderful time to pass such legislation.
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Apr 24, 2023 19:45
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Oracle posted:Given that you have to stay on it for it to remain effective and the instant you stop taking it you start gaining the weight back? I'm gonna say probably not. Willa Rogers posted:Alternatively, Congress could pass drug-price controls for Medicare beyond insulin & the handful of chemo drugs they might regulate at 2026 pricing.
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Apr 24, 2023 19:47
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zoux posted:https://twitter.com/donlemon/status/1650533617636966400 Good riddance; I hope it was bc of his telling women that they're past their prime to run for office & his other misogynies. I'm stunned that he's "stunned" about it. Yiggy posted:Yup, slow realization at fox that if they leave garbage out it’s gonna attract raccoons. CNN, too, apparently.  I wonder what the odds are of Lemon and/or Carlson joining News Nation, where Chris Cuomo went after he was fired.
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Apr 24, 2023 19:47
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Willa Rogers posted:Alternatively, Congress could pass drug-price controls for Medicare beyond insulin & the handful of chemo drugs they might regulate at 2026 pricing.
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Apr 24, 2023 19:48
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Willa Rogers posted:Alternatively, Congress could pass drug-price controls for Medicare beyond insulin & the handful of chemo drugs they might regulate at 2026 pricing. The problem is that they are so new and part of the reason they are so cost-ineffective is that you basically have to take it for the rest of your life. Even the NHS in the U.K. and other places with much stricter drug price controls won't cover it right now because they can't get the price down to a level that is cost-effective. In the U.K., you have to be dangerously obese and even then you can only get it covered for 2 years before they cut you off.
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Apr 24, 2023 19:48
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cat botherer posted:Not necessarily. Given that it's a diabetes medication, and that chronic obesity usually leads to diabetes eventually, it's potentially a good preventative. Staying on a drug like this for the rest of your life is better than the total havoc metabolic syndrome inflicts on your organs, joints, and brain. I had to cut this off at the half-million mark because there were twice the number of corporate donor names as these:     Note that these were political contributions made for the 2021-2022 election cycle. (eta: Mods, let me know if anyone complains about the length & I'll change the images to links.) Willa Rogers fucked around with this message at 01:21 on Apr 25, 2023 |
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Apr 24, 2023 19:57
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SirFozzie posted:We need a topic change. Let's not give people too much hope...
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Apr 24, 2023 20:29
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A county an hour north of Louisville has found a novel way to keep PoC in their place.quote:Myles Cosgrove, a former Louisville police officer who shot and killed Breonna Taylor in March 2020, became a law enforcement officer again in a nearby county, according to various local media outlets. System working as intended.
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Apr 24, 2023 20:32
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LA Times is confirming that Tucker Carlson was fired due to the lawsuit from his former producer against him and Fox News. It was not related to the Dominion settlement. The decision was made by Rupert Murdoch himself this weekend. His primetime slot will be replaced by a rotating group of Fox News hosts for the next few weeks until they find a permanent replacement. https://twitter.com/kylegriffin1/status/1650579126393135144 quote:Tucker Carlson departs Fox News, pushed out by Rupert Murdoch
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Apr 24, 2023 20:33
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Seems like Tucker was saying bad things about his boss and posting incriminating things about discriminating against his employees on his work email. All of it had been sitting on the email servers for years, but the Dominion lawsuit was the only reason they collected and reviewed all the information. Another wild example of "untouchable person documents all the things that will get them fired on their work email for some reason."
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Apr 24, 2023 20:43
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hmm, wonder if the ayers and o'reilly lawsuits played a role in this? i guess the hope is that if you fire the guy it makes a quit settlement much easier?
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Apr 24, 2023 20:43
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Don Lemon says he has hired Bryan Freedman (who is a legendary Hollywood attorney that represented people like Quentin Tarantino, Robert Downey, Jr., Kevin Spacey, Megyn Kelly, and Mariah Carey) to handle his departure from CNN and that he wants a large chunk of the $20 million his recent contract was worth to be paid out.
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Apr 24, 2023 20:58
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It says something, not sure what, but the fact that fox keeps canning “talent” at what appears to be top of their game (to their mouth breathing fans) somehow doesn’t faze anyone. I hear people talking about Don Lemon and carlson the same breath, talking about them as if they are completely identical. That one is “left” and the other is “right” means that they faced the exact same situation, circumstances and their departures mean the same thing and their dismissal will have the same impact (to the left is the insinuation). Weird is all I’m saying.
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Apr 24, 2023 21:00
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The FCC is working with the European Union to develop 6G standards and technology to be distributed around the world. China is pushing a competing standard that has much greater ability for carriers to view individual information. The U.S. is now (somewhat ironically) at the head of the global effort to provide 6G networks with high degrees of individual privacy protections to become the standard over the Chinese version. Obviously, China will be able to deploy whatever version it wants within its own country, but the E.U. and U.S. are working to put the money into research for the rest of the world to allow for cheaper adoption by other countries to dissuade them from allowing China to set up a global network. quote:Biden official: 'Jury is still out on how 6G will look' This is not my area of expertise. Does anyone who may know more about it know what the significant differences are with 6G that aren't simply "5G, but faster"? Or what the significance of Wi-Fi 7 is? Or what type of "much more individual identifying information" the Chinese version is working with/is that different from 5G? https://finance.yahoo.com/news/biden-official-jury-is-still-out-on-how-6g-will-look-173257234.html Leon Trotsky 2012 fucked around with this message at 21:18 on Apr 24, 2023 |
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Apr 24, 2023 21:15
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Grater posted:It says something, not sure what, but the fact that fox keeps canning “talent” at what appears to be top of their game (to their mouth breathing fans) somehow doesn’t faze anyone. I hear people talking about Don Lemon and carlson the same breath, talking about them as if they are completely identical. That one is “left” and the other is “right” means that they faced the exact same situation, circumstances and their departures mean the same thing and their dismissal will have the same impact (to the left is the insinuation). Don Lemon is among a string of CNN losers who've lost their jobs over the last couple years. Weirdly enough, Jake Tapper & Chris Cuomo each had executive producers who were child predators & arrested months apart from each other (last year, I think). Then Chris Cuomo had to hit the bricks himself. (eta: I looked it up & CNN canned these on-air folks a few months ago: Chris Cillizza, Alison Kosik, Alex Field, Martin Savidge and Robin Meade) The situations aren't "identical" between Carlson & Lemon--Carlson had way more viewers, and was on primetime while Lemon had been demoted to mornings--but it's just funny that April 24 turned out to be the day for cable-news firings. I really wish MSNBC had 86'd Reid or another of their horrible talking heads for the trifecta, though! Willa Rogers fucked around with this message at 21:19 on Apr 24, 2023 |
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Apr 24, 2023 21:17
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Grater posted:It says something, not sure what, but the fact that fox keeps canning “talent” at what appears to be top of their game (to their mouth breathing fans) somehow doesn’t faze anyone. I hear people talking about Don Lemon and carlson the same breath, talking about them as if they are completely identical. That one is “left” and the other is “right” means that they faced the exact same situation, circumstances and their departures mean the same thing and their dismissal will have the same impact (to the left is the insinuation). If Don Lemon is a symbol of the left, then politics in the US is even more messed up than I thought.
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Apr 24, 2023 21:18
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Leon Trotsky 2012 posted:This is not my area of expertise. Does anyone who may know more about it know what the significant differences are with 6G that aren't simply "5G, but faster"? Or what the significance of Wi-Fi 7 is? Or what type of "much more individual identifying information" the Chinese version is working with/is that different from 5G? I don't think any of the potential 6G proposals have advanced to the point where that question can be answered, certainly not to anyone who isn't a telecom expert
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Apr 24, 2023 21:20
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Don Lemon was a misogynistic gay black guy who had a $20 million contract and used his national platform to embarrass gun manufacturers, complain about the gay dating scene and drama in hair salons, and talk about how much he loves partying with Russell Simmons during broadcasts about kidnapped kids. I don't think there is even another individual in America who slots into his demographic. He's definitely not representative of half the country.
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Apr 24, 2023 21:22
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Leon Trotsky 2012 posted:Don Lemon was a misogynistic gay black guy who had a $20 million contract and used his national platform to embarrass gun manufacturers, complain about the gay dating scene and drama in hair salons, and talk about how much he loves partying with Russell Simmons during broadcasts about kidnapped kids. The last straw was that he said Haley was "past her prime" which allowed Haley and co. to climb up on the cross about ageism and sexism, which it was, but I hate giving Nikki Haley a dub. He also allegedly advised Jussie Smollett about the whole deal before it was even reported to the police. You may or may not agree with all the whatever surrounding Smollett but as a question of journalistic ethics, that's a no no.
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Apr 24, 2023 21:29
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Eric Cantonese posted:If Don Lemon is a symbol of the left, then politics in the US is even more messed up than I thought. I exactly what I’m saying. I’m illustrating something I’m hearing from on the ground folks from an ordinary corporate lunchroom. I’m honestly can’t figure out if this is right wingers finding a way to cope with their loss, normie folks who buy into the left vs. right fighting or actual lefties who are lamenting their loss. I tend to fall on the side of right wing cope but I can’t help but wonder…
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Apr 24, 2023 21:37
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Grater posted:I exactly what I’m saying. I’m illustrating something I’m hearing from on the ground folks from an ordinary corporate lunchroom. I’m honestly can’t figure out if this is right wingers finding a way to cope with their loss, normie folks who buy into the left vs. right fighting or actual lefties who are lamenting their loss. I think it's the regulars buying into the left/right narrative. Most people identity as independent because both parties and thus both "sides" are so toxic and corrupt that most people have ceased to care. Learning that both parties are actually right wing parties, just that the GOP are far right and Dems center right, would take way more time and effort than most people are willing to put into following politics. So from the surface it's boiled down to 2 teams fighting for who cares why. If you spent the time explaining in detail the facts of just how many ways the GOP has been trying to overthrow democracy the average non-political person would think it's just hyperbole. Ignorance is the most successful part of the GOP strategy, they sucker in the easily manipulated and discourage millions more from caring at all. Hence the gutting of education across the board.
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Apr 24, 2023 21:46
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Leon Trotsky 2012 posted:Don Lemon was a misogynistic gay black guy who had a $20 million contract and used his national platform to embarrass gun manufacturers, complain about the gay dating scene and drama in hair salons, and talk about how much he loves partying with Russell Simmons during broadcasts about kidnapped kids. There are plenty of Black gay American men, though. And Lemon's "demographic" was liberals who wanted to believe that Jussie Smollett was telling the truth about MAGA freaks putting a noose around his neck; that Republican women age like milk; and that Trump suffers from "early onset dementia" (pretty rich now given the current occupant of the WH). Half the country, or at least the third that votes blue no matter who, would've totally agreed with Lemon when he said these things. Hell, I'd bet there's still sizeable chunks who do.
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Apr 24, 2023 21:53
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I also think that we're noticing it because we're in the 99th percentile of media literacy in this country. For most people, especially Fox News people, it will be like when Michael Jackson and Farrah Fawcett died on the same day: no one noticed the latter.
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Apr 24, 2023 21:53
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I've been seeing that this interview was what made CNN decide to reshuffle Don Lemon. https://twitter.com/atrupar/status/1650563196795641871?s=20
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Apr 24, 2023 21:53
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He quit like he cried on air: performatively, and for attention.
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Apr 24, 2023 21:55
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Leon Trotsky 2012 posted:The FCC is working with the European Union to develop 6G standards and technology to be distributed around the world. 6G doesn't exist as a standard yet. Right now it is essentially "5G but faster". Everything else is just a wishlist of features that will have to be nailed down by the people actually working on establishing the standard (usually a mix of various tech/telecom companies, academic researchers, the government, etc.). koolkal fucked around with this message at 21:59 on Apr 24, 2023 |
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Apr 24, 2023 21:56
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volts5000 posted:I've been seeing that this interview was what made CNN decide to reshuffle Don Lemon. What does Rupar find notable about Harlow staying quiet during that pissing contest? And yeah, not a good look for Lemon to say "whatever ethnicity you are" regarding Ramaswamy's heritage. But it was prolly the straw that broke the Lemon's contract when added to his other poo poo shows.
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Apr 24, 2023 22:00
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FOX stock drop after Tucker got fired cost as much as the settlement to Dominion... https://twitter.com/KBAndersen/status/1650533819785658368?t=gnUL3gxTNLC56__yNQAz6g&s=19
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Apr 24, 2023 22:00
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Young Freud posted:FOX stock drop after Tucker got fired cost as much as the settlement to Dominion... Wait so they lost $787 mil to the Dominion suit AND $700 mil in stock value just now? If true then truly lol, lmao even.
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Apr 24, 2023 22:03
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Seems like a good time to remind the thread of Don Lemon's GQ "sorbette" profile.
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Apr 24, 2023 22:10
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Young Freud posted:FOX stock drop after Tucker got fired cost as much as the settlement to Dominion... When you suck so much you cost your (former) employer $700 million twice in the span of a single week.
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Apr 24, 2023 22:10
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Orthanc6 posted:Wait so they lost $787 mil to the Dominion suit AND $700 mil in stock value just now? If true then truly lol, lmao even. The stock’s probably recovered somewhat, but yes, lol Lmao that that is almost the exact same thing they used to drive home the impact of Logan Roy dying on Succession two weeks ago
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Apr 24, 2023 22:11
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Orthanc6 posted:Wait so they lost $787 mil to the Dominion suit AND $700 mil in stock value just now? If true then truly lol, lmao even. The stock drop may be temporary and everyone who owns stock in the company has lost value. The company itself doesn't own any of its stock. The Dominion settlement came 100% out of Fox News' revenue.
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Apr 24, 2023 22:12
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haveblue posted:Lmao that that is almost the exact same thing they used to drive home the impact of Logan Roy dying on Succession two weeks ago Lol, I was just thinking that too! 
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Apr 24, 2023 22:13
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zoux posted:Everything right now indicates it was extremely abrupt volts5000 posted:I've been seeing that this interview was what made CNN decide to reshuffle Don Lemon. Man this dude is like the kiss of death for interviewers, huh? 
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Apr 24, 2023 22:16
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Oracle posted:Given that you have to stay on it for it to remain effective and the instant you stop taking it you start gaining the weight back? I'm gonna say probably not. It's a weekly injection, and anecdotally a lot of patients seem to be fairly adherent to it. It produces good results and side-effects aren't a major issue for most folks. That said I can only imagine how much it will cost in the States. Either way, what a cash cow. We've already seen American MDs licensed here in Canada prescribing it to tens of thousands of Americans before getting their license here suspended.
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Apr 24, 2023 22:18
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