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Convex
Aug 19, 2010

Mebh posted:

Ozempic was the only drug that seriously helped my wife lower her insulin amounts, start to lose weight and help manage her extremely complex form of diabetes that combined insulin resistance and a hosed pancreas.

But thanks to all the weight loss trends she hasn't been able to get it on the NHS since the start of the shortages and her mental health has taken a loving nosedive.

It really loving sucks watching a tiktok trend destroy the person I love the most and there's nothing I can do about it.

i'm sorry to hear that :smith:

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Tesseraction
Apr 5, 2009

Mebh posted:

Ozempic was the only drug that seriously helped my wife lower her insulin amounts, start to lose weight and help manage her extremely complex form of diabetes that combined insulin resistance and a hosed pancreas.

But thanks to all the weight loss trends she hasn't been able to get it on the NHS since the start of the shortages and her mental health has taken a loving nosedive.

It really loving sucks watching a tiktok trend destroy the person I love the most and there's nothing I can do about it.

Christ, I'm so sorry to hear this. Is there literally no way it can be prescribed? I've been able to test medications by being a master of drama during a discussion with GP.

Mebh
May 10, 2010


They'd prescribe it happily, but every pharmacy just shrugged and said out of stock. There's literally no way to get it on the nhs as a diabetic as it's not considered "critical".

Zalakwe
Jun 4, 2007
Likes Cake, Hates Hamsters



Mebh posted:

They'd prescribe it happily, but every pharmacy just shrugged and said out of stock. There's literally no way to get it on the nhs as a diabetic as it's not considered "critical".

Can it be paid for anywhere safely you're aware? Can the hardship fund we have pay for it?

Tesseraction
Apr 5, 2009

Even if it's not within the scope of the hardship fund I could help fund a private acquisition of it.

HopperUK
Apr 29, 2007

Why would an ambulance be leaving the hospital?
You need a prescription from a private doctor.

The Question IRL
Jun 8, 2013

Only two contestants left! Here is Doom's chance for revenge...

So based on my understanding of the situation...

Do you remember two years ago when the Oxford AstraZenica Covid vaccine was supposed to be released in Europe? But there was a big whoops and all the supplies for the EU were accidentally made wrong and couldn't be released.
But there was no problem with the UK supplies so they could be released with no issue.
Oh and the US and Isreal and some other countries who could pay under the table mysteriously got some large supplies of Vaccine?

That's what the situation is like. It's not a matter of "I will pay real world money to get it!" It's that is being ring fenced to a certain type of high net worth buyer who is into this because of a combination of "trends" and diet culture indoctrinating them into fearing being fat.
It's a gross situation and one that hurts the people who really need it.
Sorry if it didn't help you stop eating cheese Emperor Boris the Incompetent.

cat botherer
Jan 6, 2022

I am interested in most phases of data processing.

HopperUK posted:

You need a prescription from a private doctor.
I'm ignorant of the UK medical situation, but does that give you preferential access to any pharmacies or are private docs more likely to have their own stash?

I know ozempic availability is worse than adderal in the US, which is really saying something. Hopefully production can be ramped up soon.

Jaeluni Asjil
Apr 18, 2018

Sorry I thought you were a landlord when I gave you your old avatar!

HopperUK posted:

You need a prescription from a private doctor.

So have pharmacies got it just not NHS supplies (not sure how that works)? Otherwise not sure how a private prescription would help if it's just not available?

Ed: Just done a bit more googling - so Mebh is the problem that her GP doesn't think she needs it for her diabetes so won't prescribe it?

Found this list of conditions so presumably she doesn't match some or any of them?

quote:


How do you qualify for an Ozempic prescription?

To receive an Ozempic prescription from your GP in the UK, here are some of the criteria you need to meet:

Have poorly controlled type 2 diabetes
Treatment with metformin is considered an inappropriate
Have a BMI of 30 or over
Have no diagnosis or family history of thyroid cancer
Have no diagnosis or family history of pancreatic cancer or pancreatitis


source https://www.secondnature.io/blog/ozempic-nhs

Jaeluni Asjil fucked around with this message at 02:16 on Jun 17, 2023

fuctifino
Jun 11, 2001

https://twitter.com/BBCNews/status/1669781547715641345

quote:

A man has been charged with stalking an MP and impersonating a police officer.

Simon Parry, 44, was arrested on Thursday following an incident with the unnamed MP in Westminster, on Wednesday.

Met Police said officers had "acted swiftly to identify, arrest and charge" the man, adding "we take the safety and security of MPs extremely seriously".

Simon Parry is one of the right wing conspiracy grifters, and I've seen his name crop up with covid stuff. I guess this is the incident in question:

https://twitter.com/Nullen80/status/1669320856860860417

HopperUK
Apr 29, 2007

Why would an ambulance be leaving the hospital?
Sorry no - the suppliers are the same for NHS and private for the most part. I was thinking in terms of getting a prescription since that's usually the trickier bit.

That said we have had stock of Ozempic in at my pharmacy. Not all strengths and not all the time but it isn't completely gone, it still trickles through.

Gonzo McFee
Jun 19, 2010

smellmycheese posted:

Lol. This is Johnson’s column tomorrow. He’s trying to become the new Adrian Chiles



Lol Boris is doing diet drug advertisements but he's too fat and lazy to just stick to a diet for a month before writing the article.

Gambrinus
Mar 1, 2005
Specialist pharmacy service stock shortage tracker says 0.25mg ozempic may be available if that's any help (it's not in my experience the most useful website so that info may be outdated).

Can she switch to e.g. liraglutide in the short term? (Am not an endocrinologist, just an internet person)

Lady Gaza
Nov 20, 2008

In the UK, drugs are approved by the regulator (MHRA, though we used to take approvals from the EMA before brexit), for a certain indication (ie weight loss in obesity). Pharma companies will apply for certain indications and regulators will decide if the evidence supports the application. For example, pharma company x may want get their drug approved in people with BMI above 27, but regulator says they only see benefit to people with BMI above 30, so that’s what the drug is approved for.

However, just because something is approved it doesn’t mean it’s available - health systems need to calculate whether it’s a good use of money/resources. This is where NICE comes in - pharma companies provide various cost effectiveness data and such, and NICE uses this and other data to work out if it’s worth funding the drug for patients. They use a measure called a QALY (quality adjusted life year) to help do this - a drug that costs a lot to provide one QALY to a patient is unlikely to get funded.

This is why you may remember various outrage stories about NICE not funding various drugs over the years. This happened a lot with cancer drugs, which provided marginal benefit over standard of care, but (no doubt influenced by pharma PR agencies) led to fuming daily mail articles. A lot of drugs for relapsed cancers may provide enough of a survival increase (eg 4 months) to get approved by the regulator but not enough of a benefit to actually be worth funding by NICE. This was why Cameron created the Cancer Drugs Fund, to provide money for drugs that NICE deemed not cost effective. Though that CDF pot got used up pretty quickly.

Private health however can pay for anything that is approved by the regulator (exceptions for covid vaccine - not available privately), even if not funded by NICE.

Microplastics
Jul 6, 2007

:discourse:
It's what's for dinner.

OwlFancier
Aug 22, 2013

Actual snakes or is that asking if you can go to the park with your cock out?

Puntification
Nov 4, 2009

Black Orthodontromancy
The most British Magic

Fun Shoe

Apraxin posted:

well, at least we're getting incisive content from it
https://twitter.com/DailyMailUK/status/1669736971911016452

So this is that banality of evil I keep hearing about.

domhal
Dec 30, 2008


0.000% of Communism has been built. Evil child-murdering billionaires still rule the world with a shit-eating grin. All he has managed to do is make himself *sad*. It has, however, made him into a very, very smart boy with something like a university degree in Truth. Instead of building Communism, he now builds a precise model of this grotesque, duplicitous world.

Guavanaut posted:

Wasn't his fault that the British nuclear codes were a spunking cock and a racial slur.

Haven't heard Radio 4 for two days. I open the safe. It's just a piece of paper with dickbutt drawn on it.

Angrymog
Jan 30, 2012

Really Madcats

OwlFancier posted:

Actual snakes or is that asking if you can go to the park with your cock out?

Actual snakes. Seems most people are actually quite happy for the guy to take his snakes to the park.

mrpwase
Apr 21, 2010

I HAVE GREAT AVATAR IDEAS
For the Many, Not the Few


I wouldn't be a very good sub commander because if I didn't hear Radio 4 for 2 days I would be too busy celebrating to do anything else1

Also probably because I would never launch a nuke

Nothingtoseehere
Nov 11, 2010


Last I remember in the lifestyle articles selling ozempic that people were paying £1000 a month for doses. When you can get that money selling it privately with such high demand, why both selling to the NHS? Pharmaceutical production will catch up in a year or two, but it's a slow process especially when there's not covid money behind it.

For a good overview on the science behind how ozempic works for weight loss I reccomend Derek Lowe's blog, a medical chemist who actually knows how this poo poo works.

https://www.science.org/content/blog-post/ozempic-and-other-glp-1-drugs-more-people-realize

Nothingtoseehere fucked around with this message at 09:21 on Jun 17, 2023

happyhippy
Feb 21, 2005

Playing games, watching movies, owning goons. 'sup
Pillbug
The wonder drug is nicotine.
Boris going to say he smokes 80 a day Embassy Blue

Magnetic North
Dec 15, 2008

Beware the Forest's Mushrooms

happyhippy posted:

The wonder drug is nicotine.
Boris going to say he smokes 80 a day Embassy Blue

Well we know he doesn't smoke Parliaments wakka wakka.

Microplastics
Jul 6, 2007

:discourse:
It's what's for dinner.
He thinks he smokes Winstons but actually smokes Basics

fuctifino
Jun 11, 2001

https://twitter.com/NadineDorries/status/1669727364106862592

:allears:

e: and a fresh CWS:

https://twitter.com/coldwarsteve/status/1669421908343889922

fuctifino fucked around with this message at 10:56 on Jun 17, 2023

happyhippy
Feb 21, 2005

Playing games, watching movies, owning goons. 'sup
Pillbug
I am pretty sure that a sign of being intelligent is not announcing how smart you are.

Mebh
May 10, 2010


Thanks for the kind posts. If we could buy it, I would have.

Basically it's being ringfenced and is unreliable in the supply she would need (vastly higher than for weight loss). To my knowledge the patent is owned by one company and they have no intention of increasing supplies as it's very expensive and complex to make and the fad is already dying down.

Stocks are supposed to return to normal next year. Woo.

I'm just really angry this was allowed to happen with off label use. As how it works for weight loss is it basically makes you too nauseous to want to eat. Pretty sure there are lots of ways to do that.

fuctifino
Jun 11, 2001

I really don't know what to make of this. What?

https://twitter.com/wesstreeting/status/1670022000805400576

e: But this has just jumped into view, and I'm lol'ing

https://twitter.com/SkyNews/status/1669856476146327553

fuctifino fucked around with this message at 11:55 on Jun 17, 2023

Kevino07
Oct 16, 2008

Angrymog posted:

Actual snakes. Seems most people are actually quite happy for the guy to take his snakes to the park.

As they should. Snakes are great. :3:

sebzilla
Mar 17, 2009

Kid's blasting everything in sight with that new-fangled musket.



He's a modern-day Frank McCourt, our Wesley

Gorn Myson
Aug 8, 2007






Just reply to it asking where you can pirate it

Nothingtoseehere
Nov 11, 2010


Mebh posted:

Thanks for the kind posts. If we could buy it, I would have.

Basically it's being ringfenced and is unreliable in the supply she would need (vastly higher than for weight loss). To my knowledge the patent is owned by one company and they have no intention of increasing supplies as it's very expensive and complex to make and the fad is already dying down.

Stocks are supposed to return to normal next year. Woo.

I'm just really angry this was allowed to happen with off label use. As how it works for weight loss is it basically makes you too nauseous to want to eat. Pretty sure there are lots of ways to do that.

Eh, not really. It depresses the appetite and makes you feel full, but not via nausea - that may be a side effect but it's not designed for it. Hopefully, it'll get approved for weight loss to help obese and production will expand so both groups can get the medicine they need.

fuctifino
Jun 11, 2001

Gorn Myson posted:

Just reply to it asking where you can pirate it

https://twitter.com/stuwyatt/status/1670027245891493888

Just Another Lurker
May 1, 2009

Nothingtoseehere posted:

Eh, not really. It depresses the appetite and makes you feel full, but not via nausea - that may be a side effect but it's not designed for it. Hopefully, it'll get approved for weight loss to help obese and production will expand so both groups can get the medicine they need.

No medical training at all but from what i read you get nausea at the start and when the dosage is upped then it settles down.

Complications are pancreatitis, bone loss and an increased chance of thyroid cancer, more work required on long term effects and once you stop taking the drug your appetite returns to what it was.

As an obese person i think i'll pass.

Gonzo McFee
Jun 19, 2010
My Scramble to the top to kick away the ladder: A Wes Streeting Story.

Guavanaut
Nov 27, 2009

Looking At Them Tittys
1969 - 1998



Toilet Rascal

The Question IRL
Jun 8, 2013

Only two contestants left! Here is Doom's chance for revenge...

Mebh posted:

Thanks for the kind posts. If we could buy it, I would have.

Basically it's being ringfenced and is unreliable in the supply she would need (vastly higher than for weight loss). To my knowledge the patent is owned by one company and they have no intention of increasing supplies as it's very expensive and complex to make and the fad is already dying down.

Stocks are supposed to return to normal next year. Woo.

I'm just really angry this was allowed to happen with off label use. As how it works for weight loss is it basically makes you too nauseous to want to eat. Pretty sure there are lots of ways to do that.

It's also a vision of what is to come from poorly regulated markets on drugs/medicines and unregulated social media*.
You are going to get trends where some dipshits will say "combine these two drugs for wonderful results!" And it will be posted and allowed to spread on some social media, and then become a craze in the real world.
Just like with Horse Wormer medication and Covid or diet craze with diabetic medicine.

Welcome to our new Cyberpunk reality.


*= Not fully the fault of social media on It's own. Legacy media feeding and stoking up political tensions and anti-intelectualisim** laid the ground work for this. But it's hard to imagine that even the most rabid crazy media organisations like GBNews and the like would run with these claims.

** = See the earlier conversation about anti-intelectualisim a few pages ago.

Kin
Nov 4, 2003

Sometimes, in a city this dirty, you need a real hero.
Is there some sophisticated subtle algorithmic thing happening on virgin media TV that makes sure whatever channel I wanna flick to has loving ads playing at that minute? Or am I just unlucky?

I swear that 9 times out of 10 I sit down, switch it on and start flipping through the guide to find something to stick on.

Then, no matter what time it is, when I do find something and stick it on, it's loving ads.

I swear I've seen more ads than actual TV shows on this thing since getting.

History Comes Inside!
Nov 20, 2004




Ads on subscription tv have always been a bit of a piss take tbh

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happyhippy
Feb 21, 2005

Playing games, watching movies, owning goons. 'sup
Pillbug
Ads are 15+ mins per hour?
So 1 in 4 chance that when you hit a channel its on ad time.
With 200+ channels you may find getting ads a lot

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