(Thread IKs:
PoundSand)
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Pingui posted:Cool article, written by a knowledgeable writer on BA.2.86. I found it thought-provoking and insightful. Subsequently it is here in full with all the bells and whistles, with highlights (by me) of some of the BA.2.86 stuff has not had much - if any - exposure. Thanks for this read, but it reminded me of a question I've been meaning to ask. When articles like these name mutations (like "T24I" or "V238L"), what do those actually mean? Are they like ... places in the DNA sequence? Something else? I didn't even know how to begin Googling for this.
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Aug 24, 2023 18:56
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| # ? May 23, 2024 03:33 |
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SardonicTyrant posted:What's the reason? tldr; more people had some level of immunity at that time via recent infection or vaccination than they did during Delta, ergo, getting an individual case of Omicron was less likely to kill you than getting an individual case of Delta was at the same time during the Delta outbreak. Which was true, if you considered that globally. Unfortunately, she then immediately extrapolated that in a very, very stupid direction quote:Let’s say that Omicron turns out to be less severe — either because it is less virulent or because there is more immunity — but more transmissible than Delta, what would it mean for the course of the pandemic going forward? Cue montage of Omicron's body count high score and the pandemic not ending
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Aug 24, 2023 19:02
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CoasterMaster posted:Thanks for this read, but it reminded me of a question I've been meaning to ask. When articles like these name mutations (like "T24I" or "V238L"), what do those actually mean? Are they like ... places in the DNA sequence? Something else? I didn't even know how to begin Googling for this. You are correct, they are locations (the number) and the substitution/mutation (the first letter is the original amino, the second one is the new one)  the outer ring here has all the codes, the inner three are combinations of DNA/RNA sequences to produce them  oh and their full names Gunshow Poophole has issued a correction as of 19:09 on Aug 24, 2023 |
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Aug 24, 2023 19:06
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honey we gotta come up with more for the party tray than just guac
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Aug 24, 2023 19:08
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Al! posted:honey we gotta come up with more for the party tray than just guac lol
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Aug 24, 2023 19:09
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Al! posted:honey we gotta come up with more for the party tray than just guac only guac can judge me live by the guac, die by the guac
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Aug 24, 2023 19:09
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https://theweek.com/covid-19/1026029/need-for-masks-new-covid-variant?refid=F22967DD63137FAA7DEF48AD35432140
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Aug 24, 2023 19:12
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Asproigerosis posted:Here's some deep lore for the thread. When I was in x-ray school, I was really frustrated with how nit picky the preceptors were being about 'the rules' to the point that I started being really obstinate to the point that I asked a nun in her 70s if there was any chance of pregnancy prior to the xrays. hell yeah
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Aug 24, 2023 19:13
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Al! posted:honey we gotta come up with more for the party tray than just guac Al! More like Jeb!
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Aug 24, 2023 19:13
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post ur favorite amino acid, mines proline, a classic, real aninoheads know
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Aug 24, 2023 19:13
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Strep Vote posted:post ur favorite amino acid, mines proline, a classic, real aninoheads know Leucine is mine, so good it's even got an impersonator
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Aug 24, 2023 19:16
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this is the one i use
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Aug 24, 2023 19:16
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Gunshow Poophole posted:You are correct, they are locations (the number) and the substitution/mutation (the first letter is the original amino, the second one is the new one) Mystery solved, thank you edit: So if I'm reading (and understanding this) right, that means the mutation V238L means that the sequence went from something like GUG to UUG (flipping that first G to a U by ~magic~) at the 238th ..base pair? amino acid? (We're really scraping the barrel of my high school biology class from decades ago) CoasterMaster has issued a correction as of 19:24 on Aug 24, 2023 |
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Aug 24, 2023 19:18
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Strep Vote posted:post ur favorite amino acid, mines proline, a classic, real aninoheads know Casein here, it makes cheese tasty when it breaks down into tyrosene
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Aug 24, 2023 19:20
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Lysine because it keeps the dinosaurs in check
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Aug 24, 2023 19:22
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The Oldest Man posted:Lysine because it keeps the dinosaurs in check oh I didn't know that was the name of the asteroid
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Aug 24, 2023 19:22
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Malgrin posted:https://theweek.com/covid-19/1026029/need-for-masks-new-covid-variant?refid=F22967DD63137FAA7DEF48AD35432140 quote:"Some kids have had pretty significant illness with this," said one California physician. "On the other hand, some kids have mild coldlike symptoms. "mainstream" news sources can be informative, but on the other hand .... Al! posted:honey we gotta come up with more for the party tray than just guac lol
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Aug 24, 2023 19:23
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CoasterMaster posted:Mystery solved, thank you V the below is a better explanation yeah. It's just the 238th amino acid in the sequence is a Leucine now instead of a Valine. Gunshow Poophole has issued a correction as of 19:30 on Aug 24, 2023 |
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Aug 24, 2023 19:27
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CoasterMaster posted:Mystery solved, thank you "V238L" refers only to the amino acid sequence of the protein. Specifically, means that the valine at position 238 in the nonmutant sequence is a Leucine in the mutant.
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Aug 24, 2023 19:28
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Al! posted:this is the one i use 
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Aug 24, 2023 19:33
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This is either a fancy new fortune telling method or a chart of Catholic feast days.
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Aug 24, 2023 19:36
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lol
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Aug 24, 2023 19:37
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Rochallor posted:This is either a fancy new fortune telling method or a chart of Catholic feast days. could be another chart catholics use
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Aug 24, 2023 19:38
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Aug 24, 2023 19:40
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Al! posted:this is the one i use 
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Aug 24, 2023 19:42
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lol
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Aug 24, 2023 19:44
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Aug 24, 2023 20:07
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genericnick posted:wtf, I thought Japan had fully specced into bidets? i call this the "rami ismail problem", because that's the name of the guy who, back in 2020, made a post about how if you have a bidet, you never need to buy or use toilet paper ever again. but the reality is, you do need toilet paper -- a bidet just doesn't get the job done entirely by itself. anyone who thinks it does, is walking around with wet turds hanging off their rear end all day. i mean, unless you're going right before you shower. which is cool if you do, but not everyone's digestive system is gonna agree to that schedule. that aside, japanese home bidets are usually just aftermarket attachments that you clip to the toilet's seat, and mildew infests the piping very easily. and blasting black, brackish water at your butt hole isn't my idea of a good time i tell you what e: furthermore, this severely underestimates japan's love of the squat toilet. [DONT] ask me about the time i had to drop a dook on the clock and there were no sitting toilets in the whole building. zero Fur20 has issued a correction as of 20:13 on Aug 24, 2023 |
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Aug 24, 2023 20:08
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Gunshow Poophole posted:You are correct, they are locations (the number) and the substitution/mutation (the first letter is the original amino, the second one is the new one) Al! posted:honey we gotta come up with more for the party tray than just guac lmao
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Aug 24, 2023 20:09
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when i wants omething outside of the IK purview i put pray emojis in the reason and it happens 50% of the time. tried and true
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Aug 24, 2023 20:10
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well now i feel silly picking my favorite amino acid on aesthetic grounds
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Aug 24, 2023 20:21
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Knowledge is knowing 20 bucks in 1987 is about 53 bucks today. Wisdom is still not paying more than 20 bucks. Nirvana is shoplifting.
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Aug 24, 2023 20:39
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https://twitter.com/wkbn/status/1694461472800133203 Gotta live your life.
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Aug 24, 2023 21:18
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StratGoatCom posted:https://twitter.com/wkbn/status/1694461472800133203  this is why turtles have to be at least 4 inches before being sold! https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/cfrsearch.cfm?fr=1240.62
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Aug 24, 2023 21:20
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The official Arizona covid app just sent me the first warning it’s ever sent me…it was about excessive heat…on one the mildest days of this summer. Some sort of metaphor there.
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Aug 24, 2023 21:23
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"I like turtles" kid devastated
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Aug 24, 2023 21:23
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Jeb! was poisoning those children. Always knew there was something off about him.
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Aug 24, 2023 21:24
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Okay, can we make an exception in the rule about blaming hostile outsiders because the Cow Exploder Rereg certainly qualifies?!?!
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Aug 24, 2023 21:24
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StratGoatCom posted:https://twitter.com/wkbn/status/1694461472800133203 try to loving stop me
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Aug 24, 2023 21:25
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| # ? May 23, 2024 03:33 |
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Master Splinter isn’t old he just has long salmonella.
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Aug 24, 2023 21:32
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