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(Thread IKs: PoundSand)
 
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fosborb
Dec 15, 2006



Chronic Good Poster

Baddog posted:

Seems like it may be more incompetence than deliberately futzing with the data to minimize, but goddamn who knows. Hospitals are already going out of their way to put admissions down as anything but due to covid.

100% incompetence. the number of people any government can hire to competently create and manage a Tableau/Power BI/ArcGIS COVID dashboard is like 1 person at best, and they sure as hell aren't hiring anyone who can adequately check their work

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Platystemon
Feb 13, 2012

BREADS
Mask policies return in US as respiratory viruses threaten to strain hospitals

Covid, flu and RSV rates creep up as vaccination rates for all three remain low, worrying healthcare providers

quote:

“We are seeing quite a dramatic increase in flu,” said Patel. Doctor’s visits for flu-like illness, which can include the flu, Covid and other illnesses, are almost at the peak of the 2019-20 season. The CDC estimates flu has been responsible for 110,000 hospitalizations and 6,500 deaths thus far this season, with hospitalizations hitting the oldest and youngest Americans hardest.

Hospital admissions for Covid are up 20.4% from the previous week, and Covid deaths are up 12.5% in the same time period, with more than 1,600 people dying from Covid in the week ending 9 December, according to the last full data set from the CDC.

IMO it only makes sense to call the category “COVID‐like illnesses”

quote:

Waves of illness like these can have long-lasting health effects. More than 5% of American adults are currently experiencing long Covid symptoms, and 14.3% have ever experienced long Covid, according to the CDC.

Oops!

quote:

Getting vaccinated is one of the most important ways to be protected, as is wearing masks in public indoor places, improving ventilation, hand washing and staying home when you’re sick. Americans can also order four free Covid tests.

For many Americans, there have been challenges to accessing these precautions. “We continue to need free masks for low-income communities, free tests and free access to antiviral medications, most importantly Paxlovid, which is being underprescribed,” Julia Koehler, an associate professor of pediatrics at Harvard medical school and a clinical pediatric infectious disease specialist, said in an email.

“The pandemic is not over,” Koehler said, but added that public messages that the crisis has ended “has led many people to abandon protective measures they may have used last year”.

Working as designed. Thank you!

blunt
Jul 7, 2005


The dashboard moved, it's now at https://ukhsa-dashboard.data.gov.uk/topics/covid-19#healthcare

Covok
May 27, 2013

Yet where is that woman now? Tell me, in what heave does she reside? None of them. Because no God bothered to listen or care. If that is what you think it means to be a God, then you and all your teachings are welcome to do as that poor women did. And vanish from these realms forever.
https://www.npr.org/2023/07/25/1189939229/covid-deaths-democrats-republicans-gap-study

This is literally old news, but I just found it today. Lont story short, I was wondering if people saying Covid mainly was killing Republicans was true. Seened silly so I googled it. Since everyone has stopped doing protective measures or updating their vaccine, I'm sure the numbers have equaled out again, but whennthe vaccines first hit that did become true. Ghoulish, regardless, but interesting in a misery tourism kind of way.

Pillowpants
Aug 5, 2006
you guys keep saying it’s incompetence but it’s also possible some very intelligent data analysts listened to the CDC doctors and now have long covid and can barely function in front of a computer.

Silent Linguist
Jun 10, 2009


Just checking, if everyone in our house tests positive, is there any need for us to mask/isolate from each other?

Soap Scum
Aug 8, 2003



Silent Linguist posted:

Just checking, if everyone in our house tests positive, is there any need for us to mask/isolate from each other?

jetz0r
May 10, 2003

Tomorrow, our nation will sit on the throne of the world. This is not a figment of the imagination, but a fact. Tomorrow we will lead the world, Allah willing.



Silent Linguist posted:

Just checking, if everyone in our house tests positive, is there any need for us to mask/isolate from each other?

No.

kreeningsons
Jan 2, 2007

can anyone please tell me why this paper should not be cited by a PA at urgent care who is actively pushing anti vaccine views on patients. because that’s what just happened to my partner, and she is pretty upset about it, but I’m too stupid to lay out criticisms beyond:

1. this is an in vitro rat model and no studies of humans have shown increased neurological diagnosis of offspring after vaccination
2. the authors take a leap of logic from behavioral anomalies in the rat offspring to “autism-like behaviors”
3. anything with autism and vaccines in the title is probably bullshit

if there are other obvious flaws with this study then I would like to hear. because that would really help me go to bat against the many, many people like this PA who are common where I live. thank you goons

https://pubmed.ncbi.nlm.nih.gov/38198049/

fosborb
Dec 15, 2006



Chronic Good Poster

kreeningsons posted:

can anyone please tell me why this paper should not be cited by a PA at urgent care who is actively pushing anti vaccine views on patients. because that’s what just happened to my partner, and she is pretty upset about it, but I’m too stupid to lay out criticisms beyond:

1. this is an in vitro rat model and no studies of humans have shown increased neurological diagnosis of offspring after vaccination
2. the authors take a leap of logic from behavioral anomalies in the rat offspring to “autism-like behaviors”
3. anything with autism and vaccines in the title is probably bullshit

if there are other obvious flaws with this study then I would like to hear. because that would really help me go to bat against the many, many people like this PA who are common where I live. thank you goons

https://pubmed.ncbi.nlm.nih.gov/38198049/

they gave the full human adult dose to the rats
it was only performed once with only 15 rats
what difference is there is extremely small
BDNF levels are actually the opposite what you'd see in autism

longer criticism:
https://twitter.com/Marc_Veld/status/1746245868179611847

toggle
Nov 7, 2005


lmao everytime!

Zugzwang
Jan 2, 2005

You have a kind of sick desperation in your laugh.


Ramrod XTreme

fosborb posted:

they gave the full human adult dose to the rats
it was only performed once with only 15 rats
what difference is there is extremely small
BDNF levels are actually the opposite what you'd see in autism
sounds like a bulletproof study to me; someone alert Bret Weinstein and Joe Rogan :thumbsup:

fosborb
Dec 15, 2006



Chronic Good Poster
drat these rats are really into trains

vaccinated?????

Paradoxish
Dec 19, 2003

Will you stop going crazy in there?

Covok posted:

https://www.npr.org/2023/07/25/1189939229/covid-deaths-democrats-republicans-gap-study

This is literally old news, but I just found it today. Lont story short, I was wondering if people saying Covid mainly was killing Republicans was true. Seened silly so I googled it. Since everyone has stopped doing protective measures or updating their vaccine, I'm sure the numbers have equaled out again, but whennthe vaccines first hit that did become true. Ghoulish, regardless, but interesting in a misery tourism kind of way.

There was a period where COVID was like the #1 cop killer

Snowglobe of Doom
Mar 30, 2012

sucks to be right

Paradoxish posted:

There was a period where COVID was like the #1 cop killer

That period being 2020 to 2022. In 2023 it apparently dropped down to 4th place: https://www.police1.com/2023-law-enforcement-fatalities-report-reveals-law-enforcement-deaths-dropped

Soap Scum
Aug 8, 2003



can someone link me the tinnitus thread? friend of mine got covid recently and said they developed new onset tinnitus and it was so bad they were borderline suicidal at its peak intensity =/ yikes

U-DO Burger
Nov 12, 2007




Soap Scum posted:

can someone link me the tinnitus thread? friend of mine got covid recently and said they developed new onset tinnitus and it was so bad they were borderline suicidal at its peak intensity =/ yikes

Right here

https://forums.somethingawful.com/showthread.php?threadid=4033474&pagenumber=1&perpage=40

bred
Oct 24, 2008
I'm on day 9. On day 6, I started testing every 12hr in the hope to end isolation with two negative tests 48 hrs apart. I tested negative each time on day 6, 7, and 8. The only symptom I had was feeling tired sooner so we ended isolation. Today I had a lot of mucus, a spicy allergy nose, dry coughing, and lots of blowing nose. Still feeling tired sooner. I feel like I had a big run earlier today. Reading the guidance, I've technically met the criteria to end isolation but I think we'll play it safe and isolate again.

I remember being in a meeting and the VP just back from being out with covid having the same symptoms as me now He was muttering "drat summer allergies." At the time I took that as excuse for us but now I think he was trying to convince himself it was only allergies.

Zugzwang
Jan 2, 2005

You have a kind of sick desperation in your laugh.


Ramrod XTreme
So what's the infectiousness window like post-symptom onset these days? A coworker of my wife's is flying in for a multi-day meeting and they pozzed about two weeks ago. I'm feeling less than sanguine about it.

Platystemon
Feb 13, 2012

BREADS

Pillowpants posted:

you guys keep saying it’s incompetence but it’s also possible some very intelligent data analysts listened to the CDC doctors and now have long covid and can barely function in front of a computer.

The thought did occur to me last week.

quote:

/r/statistics [Career] I fear I need to leave my job as a biostatistician after 10 years: I just cannot remember anything I've learned.

I'm a researcher at a good university, but I can never remember fundamental information, like what a Z test looks like. I worry I need to quit my job because I get so stressed out by the possibility of people realising how little I know.

I studied mathematics and statistics at undergrad, statistics at masters, clinical trial design at PhD, but I feel like nothing has gone into my brain.

My job involves 50% working in applied clinical trials, which is mostly simple enough for me to cope with. The other 50% sometimes involves teaching very clever students, which I find terrifying. I don't remember how to work with expectations or variances, or derive a sample size calculation from first principles, or why sometimes the variance is sigma^(2) and other times it's sigma^(2)/n. Maybe I never knew these things.

Why I haven't lost my job: probably because of the applied work, which I can mostly do okay, and because I'm good at programming and teaching students how to program, which is becoming a bigger part of my job.

I could applied work only, but then I wouldn't be able to teach programming or do much programming at all, which is the part of my job I like the most.

I've already cut down on the methodological work I do because I felt hopeless. Now I don't feel I can teach these students with any confidence. I don't know what to do. I don't have imposter syndrome: I'm genuinely not good at the theory.

bred
Oct 24, 2008

Zugzwang posted:

So what's the infectiousness window like post-symptom onset these days? A coworker of my wife's is flying in for a multi-day meeting and they pozzed about two weeks ago. I'm feeling less than sanguine about it.

The numbers I have memorized are 50% are contagious at day 5 and 5% at day 21.

silicone thrills
Jan 9, 2008

I paint things

Zugzwang posted:

So what's the infectiousness window like post-symptom onset these days? A coworker of my wife's is flying in for a multi-day meeting and they pozzed about two weeks ago. I'm feeling less than sanguine about it.

Its incredibly variable. Almost everyone I've known with covid who didnt pax it up ended up testing positive for like 13-15 days. There was someone in this thread who went like a solid 3 weeks.

Platystemon
Feb 13, 2012

BREADS

kreeningsons posted:

1. this is an in vitro rat model and no studies of humans have shown increased neurological diagnosis of offspring after vaccination
2. the authors take a leap of logic from behavioral anomalies in the rat offspring to “autism-like behaviors”
3. anything with autism and vaccines in the title is probably bullshit

4. They loving megavaxed those poor rodents.

Inject a human being with the the same proportion of body weight, and they’ll enter the astral plane and fight God.

Soap Scum
Aug 8, 2003




tyty

Phlag
Nov 2, 2000

We make a special trip just for you, same low price.


Bruce Hussein Daddy posted:

I'd like to ask these brain geniuses why if 2020 was the lowest hospitalization yet with each following year having a randomly higher level than that what conclusion can we take from that.


Do you have the source of that chart?

Pingui
Jun 4, 2006

WTF?

Phlag posted:

Do you have the source of that chart?

It's in the article, but sadly Bruce Hussein Daddy misread, as that is a graph of (currently very much estimated) cases.

The author isn't nominally wrong that the hospitalizations in the UK aren't as high as they have been, it just doesn't have anything to do with JN.1, as they have been trending downwards for literal years. Have some graphs I made:
With

Of


Source: https://www.england.nhs.uk/statistics/statistical-work-areas/covid-19-hospital-activity/

Note that the estimated cases and the above graphs don't match, unless they aren't testing as much in hospitals or they stopped registering cases. Neither of which appear to be the case (as far as I can find; though possibly the doctor strikes), indicating that the case graph the author of the original article has as the premise of his argument is overestimating cases.

Pingui has issued a correction as of 04:11 on Jan 16, 2024

Platystemon
Feb 13, 2012

BREADS
“The science says that children are practically immune to the novel coronavirus.”

The science:

https://doi.org/10.1542/peds.2023-064326 posted:

Outcomes of SARS-CoV-2 and Seasonal Viruses Among Children Hospitalized in Brazil

BACKGROUND AND OBJECTIVES:
Understanding how severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) interacts with other respiratory viruses is crucial for developing effective public health strategies in the postpandemic era. This study aimed to compare the outcomes of SARS-CoV-2 and seasonal viruses in children and adolescents hospitalized with severe acute respiratory infection (SARI).

METHODS:
This population-based, retrospective cohort study included children and adolescents hospitalized with SARI from February 2020 to February 2023 in Brazil. The main exposure of interest was viral etiology. The primary outcome was in-hospital mortality. Competing risk analysis was used to account for time dependency and competing events.

RESULTS:
A total of 235 829 patients had available results of the viral tests, with SARS-CoV-2 predominance. According to the competing-risk survival analysis, the estimated probability of a fatal outcome at 30 days of hospitalization according to the viral strain was 6.5%, 3.4%, 2.9%, 2.3%, 2.1%, and 1.8%, for SARS-CoV-2, coinfection, adenovirus, influenza, other viruses, and respiratory syncytial virus, respectively. Individuals with a positive test for SARS-CoV-2 had hazard of death 3 times higher than subjects with a negative test (hazard ratio, 3.3; 95% confidence interval, 3.1–3.5). After adjustment by the competing-risk multivariable analysis, admission in Northeast and North regions, oxygen saturation <95%, and the presence of comorbidities were risk factors for death in all viral strains.

CONCLUSIONS:
SARS-CoV-2 infection had the highest hazard of in-hospital mortality in this pediatric cohort hospitalized with SARI. Regardless of viral etiology, the presence of underlying medical conditions was a risk factor for death.



Incident cases of SARI in children and adolescents according to the viral etiology, age, and year of admission during the 3 years of the COVID-19 pandemic in Brazil.



Unadjusted hazard of death in children and adolescents with SARI according to the viral strain. Reference category: Negative test at baseline.



Cumulative incidence of death in children and adolescents with SARI according to viral strain.

Oops!

Platystemon has issued a correction as of 04:18 on Jan 16, 2024

RandomBlue
Dec 30, 2012

hay guys!


Biscuit Hider

kreeningsons posted:

can anyone please tell me why this paper should not be cited by a PA at urgent care who is actively pushing anti vaccine views on patients. because that’s what just happened to my partner, and she is pretty upset about it, but I’m too stupid to lay out criticisms beyond:

1. this is an in vitro rat model and no studies of humans have shown increased neurological diagnosis of offspring after vaccination
2. the authors take a leap of logic from behavioral anomalies in the rat offspring to “autism-like behaviors”
3. anything with autism and vaccines in the title is probably bullshit

if there are other obvious flaws with this study then I would like to hear. because that would really help me go to bat against the many, many people like this PA who are common where I live. thank you goons

https://pubmed.ncbi.nlm.nih.gov/38198049/

There are a lot of problems with it, the main one being they gave the rats a human dose that's about 330x's what they should've been given IIRC.

Zantie
Mar 30, 2003

Death. The capricious dance of Now You Stop Moving Forever.
https://twitter.com/LongDesertTrain/status/1747051492836573375

Obvious caveat of I am posting this late and can't get into it the way Ryan does. I was also going to try to post a nitter version of the link for once so more people could read it, but I guess it's down or something?

Anyway Ryan's specialty covers the types of mutations that arise from chronic infections and others from treatment with molnupiravir. Here he's posting about another chronic Delta infection sequenced from Portugal about a month ago that has the same double mutation that rocketed Omicron to ACE2 affinity stardom; Q498R-N501Y. Granted this Delta sequence isn't the greatest quality and is missing some coverage, however outside it's 30+ spike mutations it also notably has changes in our good ol' mysterious friend, ORF7a.

Zantie has issued a correction as of 07:39 on Jan 16, 2024

Steve Yun
Aug 7, 2003
I'm a parasitic landlord that needs to get a job instead of stealing worker's money. Make sure to remind me when I post.
Soiled Meat
https://x.com/drericding/status/1747062000079814712?s=46

Tulip
Jun 3, 2008

yeah thats pretty good


So I went to my parents for christmas and I've been asleep for at least 2/3 of 2024. Only your respirator trust.

mahler_biryani
Jan 28, 2023

Zantie posted:

https://twitter.com/LongDesertTrain/status/1747051492836573375

Obvious caveat of I am posting this late and can't get into it the way Ryan does. I was also going to try to post a nitter version of the link for once so more people could read it, but I guess it's down or something?


Nitter link

https://nitter.net/LongDesertTrain/status/1747051492836573375

Steve Yun
Aug 7, 2003
I'm a parasitic landlord that needs to get a job instead of stealing worker's money. Make sure to remind me when I post.
Soiled Meat


Apparently iPhones have an app called Sleep Cycle which tracks your coughing in your sleep

https://x.com/garnetstar28/status/1747119872587518328?s=46

Steve Yun has issued a correction as of 08:19 on Jan 16, 2024

Cretin90
Apr 10, 2006
My local vaccine study place has been harassing me for months to participate in an RSV vaccine trial, any reason I shouldn’t? I’m under the impression it’s really just approved for older people so as a 33 year old why the gently caress not. Obviously the recommendation may vary on the finer details of the study (pay, time period, isolation, blah blah blah) so just assume it’s a generic double blind study for the intent of this question.

Steve Yun
Aug 7, 2003
I'm a parasitic landlord that needs to get a job instead of stealing worker's money. Make sure to remind me when I post.
Soiled Meat

Cretin90 posted:

My local vaccine study place has been harassing me for months to participate in an RSV vaccine trial, any reason I shouldn’t?

obviously you don’t want to become magnetized and/or autistic

Platystemon
Feb 13, 2012

BREADS

Cretin90 posted:

My local vaccine study place has been harassing me for months to participate in an RSV vaccine trial, any reason I shouldn’t? I’m under the impression it’s really just approved for older people so as a 33 year old why the gently caress not. Obviously the recommendation may vary on the finer details of the study (pay, time period, isolation, blah blah blah) so just assume it’s a generic double blind study for the intent of this question.

If it’s one of the approved expectant parent/elderly vaccines now being trialed in healthy adults, I would take it.

If it’s something else, it depends on the platform. I would not have taken Janssen’s vaccine candidate with an adenovirus vector, but they canceled that in May of 2023. I would take Bavarian Nordic’s vaccine with a vaccinia vector, but they may not want me in the trial because I have been vaccinated against smallpox and thereby the vector itself.

e: BN also discontinued theirs in July. :capitalism:

The Oldest Man
Jul 28, 2003

Zantie posted:

https://twitter.com/LongDesertTrain/status/1747051492836573375

Obvious caveat of I am posting this late and can't get into it the way Ryan does. I was also going to try to post a nitter version of the link for once so more people could read it, but I guess it's down or something?

Anyway Ryan's specialty covers the types of mutations that arise from chronic infections and others from treatment with molnupiravir. Here he's posting about another chronic Delta infection sequenced from Portugal about a month ago that has the same double mutation that rocketed Omicron to ACE2 affinity stardom; Q498R-N501Y. Granted this Delta sequence isn't the greatest quality and is missing some coverage, however outside it's 30+ spike mutations it also notably has changes in our good ol' mysterious friend, ORF7a.

When you think about it, it's kind of a miracle of population size and modern medicine that the people who can bake these kinds of strains exist and live long enough, and in the numbers required, to make these types of chronic infection-driven nightmares possible

kazmeyer
Jul 26, 2001

'Cause we're the good guys.

Steve Yun posted:

Apparently iPhones have an app called Sleep Cycle which tracks your coughing in your sleep

https://x.com/garnetstar28/status/1747119872587518328?s=46

I've got that on Android and when they started classifying sleep sounds (all I tend to get is snores and "electronic noises") I was wondering if that could be used as a tool for this sort of thing.

Steve Yun
Aug 7, 2003
I'm a parasitic landlord that needs to get a job instead of stealing worker's money. Make sure to remind me when I post.
Soiled Meat
Bah. Sleep Cycle wants $40 a year

edit: 7 day free trial

edit: bah they won’t show me the Danger Radar until I use the app for one night first

Steve Yun has issued a correction as of 09:58 on Jan 16, 2024

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Zodium
Jun 19, 2004

Salt Fish posted:

I think climate and covid thread posters are different groups because you have a budget for digesting grim reality and it starts to stretch thin.

skill issue

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