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Xiahou Dun posted:Trump didn't have a dog, which is a very easy way to guarantee no bites. Eric has been very well trained. zoux posted:The crowd consensus would agree I would have lost my bet here as well, she was trending well to be VP before she started blasting.
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# ? Apr 29, 2024 18:22 |
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# ? May 17, 2024 02:23 |
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Leon Trotsky 2012 posted:The research, development, and testing for the drugs was very time-consuming and expensive, but the actual production isn't very expensive. It is true that is where the cost lies, but pricing is not actually connected to the cost of a drug or why drugs are expensive. That’s a function of anti-competitive practices by manufacturers and permissive regulatory environment that allows for practices such as evergreening patents. When you look where pharma companies actually spend their money most years they spend more on marketing than R&D. Much of the huge research cost is also heavily subsidized and done via public private “partnerships” that allow for private companies to maintain IP while using labor and facilities paid for by public universities and public grants. Otherwise the price of insulin minus the manufacturing cost insulin would be cheaper than any other drug since the IP was given for free before companies were able to evergreen their own “formulas.” The reason its expansive is because of cartel like control of markets and the fact that many people will die or suffer without it. Butter Activities fucked around with this message at 18:26 on Apr 29, 2024 |
# ? Apr 29, 2024 18:23 |
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You know that Pharma has too much money when they are advertising tons of drugs on TV that have to be prescribed by a doctor. That shouldn't be a thing.
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# ? Apr 29, 2024 18:27 |
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Butter Activities posted:It is true that is where the cost lies, but pricing is not actually connected to the cost of a drug or why drugs are expensive. That’s a function of anti-competitive practices by manufacturers and permissive regulatory environment that allows for practices such as evergreening patents. When you look where pharma companies actually spend their money most years they spend more on marketing than R&D. Much of the huge research cost is also heavily subsidized and done via public private “partnerships” that allow for private companies to maintain IP while using labor and facilities paid for by public universities and public grants. to my understanding, its expensive because the improved versions of insulin medication we use these days in the US are indeed patented, with the semaglutides that have exploded in popularity being a case in point. Old insulin isn't recommended.
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# ? Apr 29, 2024 18:49 |
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Butter Activities posted:Otherwise the price of insulin minus the manufacturing cost insulin would be cheaper than any other drug since the IP was given for free before companies were able to evergreen their own “formulas.” The reason its expansive is because of cartel like control of markets and the fact that many people will die or suffer without it. Modern insulin is substantially different from the original freely licensed formulation in ways which are basically life-changing due to the variety of onsets and durations available to manage levels. The rest of your post is accurate but downplaying the development of modern insulins weakens your point significantly. TheDeadlyShoe posted:to my understanding, its expensive because the improved versions of insulin medication we use these days in the US are indeed patented, with the semaglutides that have exploded in popularity being a case in point. Old insulin isn't recommended. Yeah most people use a combination of rapid onset and long acting insulins now.
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# ? Apr 29, 2024 18:57 |
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Butter Activities posted:It is true that is where the cost lies, but pricing is not actually connected to the cost of a drug or why drugs are expensive. That’s a function of anti-competitive practices by manufacturers and permissive regulatory environment that allows for practices such as evergreening patents. When you look where pharma companies actually spend their money most years they spend more on marketing than R&D. Much of the huge research cost is also heavily subsidized and done via public private “partnerships” that allow for private companies to maintain IP while using labor and facilities paid for by public universities and public grants. This is all true, but the assumption is that the drugs will go generic in 2031 as planned. Obviously, if there was some sort of extension on the patent, then the situation would change. But, the production costs for GLP-1 type drugs like WeGovy and Ozempic are fairly low and when they go generic they should be a fraction of the cost they are now. Ozempic and WeGovy are expensive now because there is a huge production shortage and Novo Nordisk is the only one who is allowed to manufacturer or sell those specific formulations right now due to their patent exclusivity. Insanely, Novo Nordisk is actually missing out on an incredible amount of money because their production capacity is very limited since they, for some reason, did not expect the drug to be as popular as it ended up being and can't meet demand. Leon Trotsky 2012 fucked around with this message at 19:02 on Apr 29, 2024 |
# ? Apr 29, 2024 18:59 |
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TheDeadlyShoe posted:to my understanding, its expensive because the improved versions of insulin medication we use these days in the US are indeed patented, with the semaglutides that have exploded in popularity being a case in point. Old insulin isn't recommended. While it doesn't really detract from your main point, the pharmacy pedant in me needs to distinguish that semaglutide is a different category of drug than insulin, with a different development than insulin's rather unusual history. Both insulin and semaglutide can be used to illustrate issues regarding drug pricing, but it'll definitely confuse issues to substitute one for the other in discussion of drug economics.
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# ? Apr 29, 2024 19:06 |
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The first new nuclear power plant project in the U.S. in decades was fully completed and went online today. The new reactors are located in Georgia and were the culmination of a long-delayed project that started in 2006. The first reactor of the project was finished in late 2023 and the second reactor was just finished. The projects were finally pushed across the finish line after the federal government guaranteed $12 billion in loans to finish construction. Despite being carbon-free and the first new nuclear project in the U.S., the major problems that have traditionally hurt nuclear power plants have plagued this new project as well. - Costs overran much higher than expected with delays. The initial estimate was a total cost of $16 billion. It ended up costing $31 billion, including $12 billion in loan guarantees from the federal government. The project was also originally projected to be finished in 2017, but was put on hold due to unexpected costs and construction delays. - The power generated from it will never be cheaper than coal, natural gas, or solar and it will take nearly 80 years to break even. The feds are putting more money behind nuclear through loan guarantees and new federal funds spent to keep existing nuclear power plants running. Additionally, there is a movement to restart construction on two nuclear powerplants in South Carolina that were abandoned halfway through construction due to cost overrun. The rate increases they need to charge to pay for nuclear power are a strong disincentive for private industry and also a political problem for government funding. However, this new reactor is the first step forward for American nuclear power in decades and may be the start of a trend if they can overcome the issues with costs and delays associated with nuclear power in the future. https://twitter.com/AP/status/1785001107162370203 quote:ATLANTA (AP) — The second of two new nuclear reactors in Georgia has entered commercial operation, capping a project that cost billions more and took years longer than originally projected. Leon Trotsky 2012 fucked around with this message at 19:29 on Apr 29, 2024 |
# ? Apr 29, 2024 19:21 |
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FlamingLiberal posted:You know that Pharma has too much money when they are advertising tons of drugs on TV that have to be prescribed by a doctor. That shouldn't be a thing. I'm fairly sure advertising drugs on TV (and maybe in general) is illegal in quite a few places. I think it's an EU-wide rule, not sure about elsewhere.
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# ? Apr 29, 2024 20:00 |
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The Feds are trying to launch an all-out assault on America by airdropping in grizzly bears and wolves into the backyards of innocent Colorado and Washington residents. https://twitter.com/nytimes/status/1785017493846663658 quote:Federal Agencies to Restore Grizzly Bears in Washington State https://twitter.com/bresreports/status/1785000612100215134 Shooting Blanks posted:I'm fairly sure advertising drugs on TV (and maybe in general) is illegal in quite a few places. I think it's an EU-wide rule, not sure about elsewhere. The U.S. and New Zealand are the only countries in the world where it is legal. Some places allow limited ads that are "Hey, we sell X drug here!" style ads, but only New Zealand and the U.S. allow completely general direct to consumer ads. Edit: For prescription drugs specifically. I'm pretty sure direct to consumer ads for non-prescription drugs are allowed in most places, but don't know all the specifics. I'm sure it varies in every place for non-prescription drugs. Leon Trotsky 2012 fucked around with this message at 20:06 on Apr 29, 2024 |
# ? Apr 29, 2024 20:01 |
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I think the government should not train bearatroopers
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# ? Apr 29, 2024 20:09 |
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zoux posted:I think the government should not train bearatroopers They never told us BBB stood for Build Better Bears.
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# ? Apr 29, 2024 20:13 |
zoux posted:I think the government should not train bearatroopers It's in the goddam constitution!!!!!
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# ? Apr 29, 2024 20:15 |
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It's necessary to control the regions overpopulation of libertarians.
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# ? Apr 29, 2024 20:21 |
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The government should probably tax industry its carbon cost, because right now the reason why coal and whatever is cheaper is because its costs are externalized to the third world getting affected by climate change while nuclear is mandated by law to internalize its costs and safety concerns. Plus the more nuclear power plants that are built the cheaper it will get as the US builds back that knowledge.
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# ? Apr 29, 2024 20:30 |
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Kale posted:Curious to see if Margie plans on looking stupid tonight by triggering the motion to vacate and the Dems probably giving enough hall passes to save him as a bone for getting the bill passed across party lines. Like this time the speaker isnt going anywhere clearly. If the Dem was a really opposition party they would use this to pass policies aimed at increasing the chances of getting reelected. But...
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# ? Apr 29, 2024 20:31 |
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Texas joins Florida in saying they will not comply with the Biden administration's new Title IX regulations for transgender students and sexual assault. This puts Texas' federal education funding under jeopardy as well. Texas gets a much smaller share of its education money from the feds than Florida (only 6% and part of that is money for school lunches or other "education" programs that can't be withheld), but it would still be a potential loss between $500 million and $1.5 billion for Texas. Louisiana, South Carolina, Oklahoma, and Wyoming have also protested the new Title IX rules and vowed to do something about it, but haven't actually said they would require schools to not enforce them. Instead, those states have called the rules "deeply troubling" and say they will "encourage local schools and universities to ignore them." https://twitter.com/thehill/status/1785029048650862744 quote:Texas governor says state will ignore ‘illegal’ Biden Title IX revisions
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# ? Apr 29, 2024 20:39 |
What's the mechanism by which Texas loses that budgeted money? Who is responsible for directing that the allocations not be sent to the states?
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# ? Apr 29, 2024 20:40 |
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I still have no idea how Texas banning DEI programs is legal under Title IX
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# ? Apr 29, 2024 20:42 |
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mdemone posted:What's the mechanism by which Texas loses that budgeted money? Who is responsible for directing that the allocations not be sent to the states? Title IX of the amendments to the 1972 Education Act requires that the DOJ and DOE either require any organization that receives any federal money not discriminate on the basis of sex in education or they must withhold all grants and "federal financial assistance" from the institutions that do not comply. Note that this is on a per institution basis, so if an individual school complies, then it doesn't matter what the state says. However, it depends on whether state law allows the Governor or Board of Education to require local schools or public universities to follow or reject those requirements. It also binds private universities that receive federal financial assistance. There are definitely going to be a bunch of lawsuits at the state level and at least one at the federal level that goes to the Supreme Court if the states force some schools to reject it and still demand the money. https://www.justice.gov/crt/title-ix#A.%C2%A0%20Federal%20Financial%20Assistance quote:Title IX prohibits, with certain exceptions, any entity that receives "federal financial assistance" from discriminating against individuals on the basis of sex in education programs or activities.11 The clearest example of federal financial assistance is the award or grant of money. However, federal financial assistance may also be in nonmonetary form. See United States Dept of Transp. v. Paralyzed Veterans, 477 U.S. 597, 607 n.11 (1986). As discussed below, federal financial assistance may include the use or rent of federal land or property at below market value, federal training, a loan of federal personnel, subsidies, and other arrangements with the intention of providing assistance.
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# ? Apr 29, 2024 20:48 |
They're probably correctly guessing that Biden's not going to do poo poo about their defiance. Just like he hasn't done poo poo about half of America's trans kids losing healthcare
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# ? Apr 29, 2024 20:48 |
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Nissin Cup Nudist posted:I still have no idea how Texas banning DEI programs is legal under Title IX It depends what specific programs you are talking about. DEI programs generally don't ban or unban women from accessing public school or university facilities or programs. They are usually essentially diversity training or affirmative action programs that aren't covered under Title IX.
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# ? Apr 29, 2024 20:53 |
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Queering Wheel posted:They're probably correctly guessing that Biden's not going to do poo poo about their defiance. Just like he hasn't done poo poo about half of America's trans kids losing healthcare The DOE already said that they are required by law to deny the federal money to schools that don't comply. quote:In an emailed statement, an Education Department spokesperson said public schools across the country are required by law to update their policies to comply with the new regulations, regardless of whether officials in their state agree with them. Doing otherwise may jeopardize federal education funding. DeSantis is also sort of walking back his threat to require all schools to not comply and instead is just generally saying they will "fight back" and not making any specific promises. quote:Florida Gov. Ron DeSantis (R) said the state plans to “fight back” against the new regulations, which he said undermine the right of parents to control their children’s education. Florida’s Parental Rights in Education Act, signed by DeSantis in 2021 and expanded late last year, prevents teachers from addressing sexuality and gender identity in the classroom.
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# ? Apr 29, 2024 20:58 |
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Queering Wheel posted:They're probably correctly guessing that Biden's not going to do poo poo about their defiance. Just like he hasn't done poo poo about half of America's trans kids losing healthcare Do you have evidence for the former or an argument that there's a relevant link between these two statements and third evidence that he has in fact not done anything about the latter claim or that its in his power to do so?
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# ? Apr 29, 2024 20:59 |
Raenir Salazar posted:Do you have evidence for the former or an argument that there's a relevant link between these two statements and third evidence that he has in fact not done anything about the latter claim or that its in his power to do so? And now you want to loving argue. Why is it that red state governors/GOP leadership can increasingly do whatever they want, but when Biden does jack poo poo in response y'all are like BuT hE cAn'T bEcAuSe LaWs The GOP just keeps taking more and more poo poo from trans people with barely a peep from the Biden admin and y'all are like HeS jUsT a SmOl BeAn He won't even stand up to Florida when they invalidate trans people's driver's licenses and call them fraudsters, even though he could easily do something since they're not complying with the federal REAL ID requirements. That's an easy one to fight! If he won't even do that then idk why you think he'll fight the more serious poo poo (USER WAS PUT ON PROBATION FOR THIS POST)
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# ? Apr 29, 2024 21:48 |
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Queering Wheel posted:And now you want to loving argue. Why is it that red state governors/GOP leadership can increasingly do whatever they want, but when Biden does jack poo poo in response y'all are like BuT hE cAn'T bEcAuSe LaWs The Real ID act—thankfully, given it was passed in 2005—doesn't have anything to say about how the states make a determination of someone's gender nor does it give the power to dictate it to the executive branch. It simply requires that one's gender is listed. What, specifically, would you have him do about what the red states are doing? I'm legitimately interested to hear it.
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# ? Apr 29, 2024 22:06 |
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Queering Wheel posted:And now you want to loving argue. Why is it that red state governors/GOP leadership can increasingly do whatever they want, but when Biden does jack poo poo in response y'all are like BuT hE cAn'T bEcAuSe LaWs There are a lot of things state governments currently have the rights to do that the federal government doesn’t have the right to stop. Thats why you see this playing out through things like Title IX; federal funding is one of the only real tools the federal government has, especially when one and a half branches of the government is controlled by Republicans.
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# ? Apr 29, 2024 22:28 |
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Kagrenak posted:The Real ID act—thankfully, given it was passed in 2005—doesn't have anything to say about how the states make a determination of someone's gender nor does it give the power to dictate it to the executive branch. It simply requires that one's gender is listed. The Real ID act isn't enforceable until May 2025, but there have been people suggesting that in 2025 (assuming Biden is reelected) the Department of Homeland Security declare Florida IDs out of compliance with Real ID because they won't allow residents to change their gender. Florida uses biological sex as the basis for the gender slot and some people argue that the definition could conflict with the federal government's definition and the DHS could use that to declare Florida's driver's licenses as invalid Real ID. If Florida is out of compliance, then people from Florida won't be able to use their driver's license as ID for planes and it would be such a huge hassle that Florida would change the law.
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# ? Apr 29, 2024 22:30 |
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Leon Trotsky 2012 posted:The Real ID act isn't enforceable until May 2025, but there have been people suggesting that in 2025 (assuming Biden is reelected) the Department of Homeland Security declare Florida IDs out of compliance with Real ID because they won't allow residents to change their gender. Florida uses biological sex as the basis for the gender slot and some people argue that the definition could conflict with the federal government's definition and the DHS could use that to declare Florida's driver's licenses as invalid Real ID. Ah interesting, thanks for this. My read of it was that it doesn't provide for this type of nitpicking. Do you know if the enforcement date is a rules thing or legislation passed to delay implementation? Kagrenak fucked around with this message at 22:39 on Apr 29, 2024 |
# ? Apr 29, 2024 22:37 |
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The enforcement date has force of law. You can even go to the DHS website and they have a giant countdown timer til it takes effect. Some states still refuse Real ID requirements for drivers licenses because they're designed to gently caress over brown people, which is gonna make it take passports to fly planes instead of drivers licenses. Lol. It remains to be seen how that's going to shake out, and whether states or Congress will blink first.
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# ? Apr 29, 2024 22:48 |
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Leon Trotsky 2012 posted:The Feds are trying to launch an all-out assault on America by airdropping in grizzly bears and wolves into the backyards of innocent Colorado and Washington residents. I think this will work out well for the wolves but probably not so well for grizzly bears. We have a lot of deer that need culling and wolves are good at that. Grizzlies can hunt deer but not to the same extent wolves do. Also our salmon populations still need a lot of work, they probably won't be a reliable source of food for them for a long time.
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# ? Apr 29, 2024 22:51 |
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TheDeadlyShoe posted:The enforcement date has force of law. You can even go to the DHS website and they have a giant countdown timer til it takes effect. DHS certified that every state is Real ID compliant back in 2020. quote:Q: Are all states issuing REAL ID compliant cards? https://www.dhs.gov/real-id/real-id-faqs
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# ? Apr 29, 2024 22:57 |
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Freakazoid_ posted:I think this will work out well for the wolves but probably not so well for grizzly bears. We have a lot of deer that need culling and wolves are good at that. Grizzlies can hunt deer but not to the same extent wolves do. Also our salmon populations still need a lot of work, they probably won't be a reliable source of food for them for a long time. Apparently, a Grizzly Bear's diet mostly consists of plants. I had no idea. quote:What Does It Eat? In their historic range: Grizzly bears are omnivorous and 75% of the food they eat is plant-based such as fruits, roots, grasses and nuts. They also apparently eat just about anything: quote:Grizzly bears mainly get their food from eating insects, grass, broad-leaved herbs, tubers, sedges, berries, and roots. Apart from these foods, a grizzly bear will often get its daily nourishment from salmon, deer, moose, ground squirrels, mice, bison, and marmots. Due to their scavenging behavior, it is not rare to find them eating rotting animal carcasses.
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# ? Apr 29, 2024 23:04 |
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Leon Trotsky 2012 posted:DHS certified that every state is Real ID compliant back in 2020. Oh, i'm heavily out of date. It seems many states now have two-tiered licenses now so you can get either a non-compliant or compliant IDs.
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# ? Apr 29, 2024 23:05 |
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Queering Wheel posted:And now you want to loving argue... Can this be the title of D&D? But seriously, it's super cool how these states care more about hurting queer people than getting free money for schools. I have to assume it's a sneaky way to cut funding to liberal indoctrination centers, but are there really people who'd object to the cuts who wouldn't see through this tactic? Blue Footed Booby fucked around with this message at 23:55 on Apr 29, 2024 |
# ? Apr 29, 2024 23:51 |
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Reminder that people are dying every day because of states refusing the Medicare extensions in the ACA, leading to hospital closure. They have no problems loving over their own citizens.
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# ? Apr 30, 2024 00:01 |
Kagrenak posted:What, specifically, would you have him do about what the red states are doing? I'm legitimately interested to hear it. I don't know, I'm not the loving president! I'm not the most powerful person in the world with practically unlimited resources who's currently sitting on his hands while like half the states in the union are marching toward making it illegal for me to exist. I'm just a loving dumb nerd who wants to enjoy the treats of life without having to worry about being directly targeted by my state government (and soon to be federal if Trump wins, jesus christ I'll probably be loving dead in a year or two if that happens lol) The only things currently helping the situation are state/local organizations fighting this poo poo, and court decisions that go in our favor. But state/local organizing can only do so much, and not all the court battles will be won because some courts are packed with MAGA judges, including SCOTUS. All of this poo poo should already be federally illegal because the PPACA says you can't discriminate based on sex, among other things, but I guess that doesn't count for trans people because ~reasons~ edit: also, gently caress you! I mean seriously, gently caress you. Quit loving sealioning with stupid questions like this, I see what you're doing. (USER WAS PUT ON PROBATION FOR THIS POST) Queering Wheel fucked around with this message at 00:18 on Apr 30, 2024 |
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# ? Apr 30, 2024 00:03 |
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Queering Wheel posted:I don't know, I'm not the loving president! I'm not the most powerful person in the world with practically unlimited resources who's currently sitting on his hands while like half the states in the union are marching toward making it illegal for me to exist. I'm just a loving dumb nerd who wants to enjoy the treats of life without having to worry about being directly targeted by my state government (and soon to be federal if Trump wins, jesus christ I'll probably be loving dead in a year or two if that happens lol) So he should do something, but you don't know what it is, and you're going to yell and scream at anyone who asks you what you think he should do.
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# ? Apr 30, 2024 00:27 |
Fart Amplifier posted:So he should do something, but you don't know what it is, and you're going to yell and scream at anyone who asks you what you think he should do. Uh, yeah?
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# ? Apr 30, 2024 00:32 |
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# ? May 17, 2024 02:23 |
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In a very funny update to that excellent news about automatic refunds from airlines last week comes a bipartisan attempt to immediately get rid of that: Link to the summary and bill https://www.commerce.senate.gov/2024/4/bipartisan-bicameral-faa-reauthorization-act-heads-to-senate-floor https://twitter.com/senwarren/status/1785049761256452142
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# ? Apr 30, 2024 00:34 |