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El Jeffe posted:I've got some B12 supplements that contain about 42,000% the daily value per pill. Why put so much in it? Is B12 so cheap that an inert filler would actually be more expensive or something? Lots of diseases can break various parts of that process, leading to pernicious anemia because you don't have enough B12 to make red blood cells. A little bit of passive absorption still happens though (~1% of the healthy rate) and you can easily pee out excess, so you can treat anything that breaks the active mechanism by just throwing 1000X amounts at it, getting a few ug passively absorbed, and pooping out 99% of the ingested B12.
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Oct 20, 2023 05:12
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BonHair posted:Do you have an oven that goes to 400, is it good, what does your pizzas look like and what kind is it?
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Oct 31, 2023 20:43
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Electric toothbrushes are roughly equivalent to manual if you hold everything else constant and study rates of tooth/gum disease. If you compare a group told to brush their teeth with a manual toothbrush to a group told to use an electric toothbrush with a built in 2min timer, the electric is better. Most of the value is from the timer, people won't actually brush long enough on their own. An electric toothbrush is a fine package for a timer though.
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Nov 2, 2023 21:08
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Tradition, mostly. Back when photography was hard and complicated, newspapers still wanted pictures to go with stories about trials. So they'd hire an artist to sit in the public area and quick sketch (mostly line drawings since they'd go into black and white). Judges didn't like it, but lost the legal fight about kicking them out as long as it wasn't disruptive. Artists switched to pastels when papers became able to do color since they're still fast, and that's the modern style. They're in court as members of the public, not part of the court infrastructure It hasn't been that long since cameras could silently take good pictures without any flash, and there's inertia plus some courts still ban photography
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Nov 3, 2023 22:20
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Silver Falcon posted:Room is the easiest one. A contained space, like in your house. May or may not have something in it! Room is more indirect, I think. It's a spelunking term for an open area inside a cave. Then it got into games via intended-as-caving-slang descriptions in ADVENT/Collasal Cave back on 1970s mainframe computers ("You are in a large room. Crawls lead northwest and south"), and then genericized
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Nov 6, 2023 22:35
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dupersaurus posted:Your employer is paying part of the monthly premium, and maybe negotiated a better price 80% employer paid, 20% employee paid is typical. https://www.bls.gov/news.release/ebs2.t03.htm Some states also require at least 50% employer paid, and there's some ACA/IRS things that also kick in for employer penalties/credits for being over/under 50%
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Nov 9, 2023 02:04
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two fish posted:Remember back in the 90s when you'd see all those rebate offers on the PC game boxes? If you discount the game, everybody pays less. If you do a mail in rebate, lots of people won't bother to send it in, wait a month or two, then deposit the check, so you get more money. It's a method for economics 101 price discrimination: charge everybody the highest price they are willing to pay. You still make sales to people who are very price sensitive and wouldn't buy it without the rebate, and still mostly charge higher prices to people who don't care enough to go through the trouble.
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Nov 19, 2023 20:32
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JacquelineDempsey posted:Why are some people so adamant about using tap vs. chip on cc readers? For context, the chip readers at my job are 100% functional, but the tap reader is hit or miss. So I end up having this conversation a jillion times a day: alnilam posted:Point of sale systems are expensive as gently caress and as long as the old way was working well enough, i have to imagine it was pretty low priority to change over. Originally everywhere (in the days of swipe/number only) it was "If the cardholder disputes a transaction, it gets reversed unless the retailer/bank can prove that they actually did it" Chip+PIN adoption in the Europe was done alongside regulation changes to "If it was a swipe transaction, old rule still applies. If it was a chip+PIN transaction, burden of proof is reversed and the cardholder is liable unless they can actively prove it wasn't them". That makes spending money on a new POS system more attractive since you get to shed liability as well as reducing fraud costs. In the US, the government didn't allow switching the burden of proof like that. So the cost/benefit for replacing POS systems didn't have the liability shifting part, just "Is the amount of fraud this will prevent more expensive than the POS cost?", so adoption took longer.
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Dec 1, 2023 08:00
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for whites => has bleach or a bleachlike in it that will attack color dyes. Use on white cloth only. Will whiten it. for colors => doesn't have bleach/bleachlikes. Use on either white or dyed cloth. Won't whiten it, your white shirts will tend towards gray/yellow over time. for whites and colors => has a bleachlike in it that is supposed to not attack common color dyes, only other stains. Use on either white or dyed cloth. Will whiten your white shirts, hopefully won't mess up your colored shirts.
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Dec 1, 2023 22:40
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Killingyouguy! posted:since celiac is a problem with your dna not creating a certain protein correctly, is it possible to have just a mild case of celiac or is it an all-or-nothing thing And the actual disease requires producing anti-self antibodies, which may not happen even if you have genetic vulnerability. The antibody level will also influence disease severity; as you go without eating gluten, antibody levels drop. When doing blood testing (looking for anti tissue transglutaminase antibodies), you need the person to have been regularly eating wheat prior. If they're already gluten-free, it will be falsely negative. Symptomatically, somebody with celiac who eats gluten rarely (like multiple months between) will have less bad symptoms on the same exposure than someone who eats it every day because antibody levels won't have upregulated as much.
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Dec 3, 2023 03:13
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They would like you to stay back, because if there is no actual damage, there is no damage for them to be liable for. They are still liable for damage caused by improperly secured loads. Phrasing it as 'we are not responsible for' is a lie, but there's no law against lying and it might get people to comply Example law from California: 
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Dec 3, 2023 03:32
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Earwicker posted:what are the consequences of life without an upper second molar?
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Dec 3, 2023 20:52
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lobsterminator posted:Not sure how correct it is but the IMDB format is pretty straightforward regarding any type of name changes, so they have the current name and "credited as" if it appeared in the movie. Which would be B in your example, but maybe the simple "as" wording is better than "then known as".
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Dec 5, 2023 05:05
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Killingyouguy! posted:Why are whole blood and plasma two different types of blood donation? If they need plasma can't they extract it from the blood in the bank? Whole blood donation frequency and how much you can take at once is limited by the person needing to keep enough red cells, and time to remake them before the next one. If you take only plasma at donation time instead of RBCs too, you can get more plasma at once, as well as donate again sooner since it's faster to regenerate. If demand for plasma is higher than the normal plasma:RBC ratio, some plasma only donations will fill that better Foxfire_ fucked around with this message at 17:57 on Dec 19, 2023 |
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Dec 19, 2023 17:54
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Alan Smithee posted:do it work tho
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Dec 20, 2023 03:38
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Preemergance seeds use gravity to know which way the stem should grow
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Dec 30, 2023 08:25
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ATP is pretty crap as far as energy density goes and also has osmotic problems since it's a bunch of individual molecules, which is why it's not really used for energy storage by living things. Polymers (fats, starches, glycogen, ...) are more common for long term storage and glucose for short term storage. Your assassin monster doesn't need a digestive system, but it should still have a liver for metabolism between energy stores and a respiratory system so it doesn't have to carry its own oxidizer (like jet engine vs rocket engine efficiency differences) Foxfire_ fucked around with this message at 23:32 on Jan 9, 2024 |
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Jan 9, 2024 23:30
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KOTEX GOD OF BLOOD posted:My understanding is that LED lights emit little to no UV radiation. More relevantly for your plan, a good grow light will intentionally include a UV component because that's beneficial for plant health.
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Jan 16, 2024 19:57
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YggiDee posted:I've got a little desk that rolls over my bed, like so:
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Jan 19, 2024 00:59
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it works for 80% of my purposes but it's also way too easy to topple over, is there a good way to stabilize it? can I just tape some weights to the bottom or something?
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I doubt you'll find a much cheaper car+driver hire than that $450. There probably isn't a paying fare on the way back. 225 miles there-and-back at $0.67/mile IRS mileage rates is ballpark $300 for car costs. $150/8 hour round trip drive time is about $19/hour. There's not much room to undercut and be dramatically cheaper, even if it's just a guy who owns and operates his own car.
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Feb 13, 2024 04:54
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Fruits of the sea posted:Yeah, IIRC there are some amino acids and vitamins (B?) that can be lacking if you're not balancing a soy-based diet with enough other foods. Haven't heard of anybody having complications because of it that weren't due to a poorly thought out diet. Soy on its own is good enough in all essential amino acids, you are fine with it as your major/only protein source
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Feb 13, 2024 22:16
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Traditional fermented vegetarian foods like kimchi, saurkraut, pickles, or whatever don't contain useful amounts of B12. Modern supplements are from isolating and culturing particular bacterial strains. Getting enough on a strict vegan diet pretty much doesn't happen without modern technology. Veganism is rare to nonexistent historically outside of subgroups like ascetic monks where poor health was expected. The taditional Jain or Buddhist diet is lacto-vegetarianism, not veganism e: most seaweed species have no useful B12 for mammals. They have a similar structure molecule that can be used similarly by other species, but mammals don't have a pathway to utilize Foxfire_ fucked around with this message at 00:07 on Feb 14, 2024 |
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Feb 14, 2024 00:00
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Teriyaki Hairpiece posted:What's the best way to store a bunch of hats? 
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Feb 18, 2024 03:46
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Atahualpa posted:It's especially good to know that you can still get the Vitamin D benefits in the shade, since I live somewhere that gets 100+ degree temperatures for 3-4 months each year. It's probably better to wear sunscreen and get vitamin D from food/supplements instead of UV to avoid skin cancer risk
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Feb 24, 2024 19:09
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Shelter as best you can. Hospitals are generally built so that collapse isn't a huge risk, and ORs aren't going to be exterior anyway. Plans for most places are public if you want to read. Here's the University of Toledo hospital's for example. They get patients away from windows and into bathrooms to shelter in each ward. Foxfire_ fucked around with this message at 03:16 on Feb 29, 2024 |
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Feb 29, 2024 03:14
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B12 uptake is active, complicated, and very efficient. Dedicated B12 supplement doses are sized to get sufficient uptake even when all that machinery is broken. A protein in spit binds to B12 and protects it from stomach acid. Past the stomach, a pancreatic enzyme splits that apart, and it binds to a different protein that was secreted by stomach cells. Then that complex gets actively pumped across the membranes of specific cells located at the end of the small intestine. The common way B12 deficiency happens is that something is broken in that process, usually autoimmune disease in the stomach/pancreas/terminal illeum, not from insufficient vitamin in food (unless you're a vegan) You treat deficiency by not relying on normal uptake and just hucking massive amounts of vitamin at the problem. About 1% or so will survive the stomach and be absorbed passively. Excess B12 gets peed out, so it's not a problem if someone with a functional B12 absorption system eats it.
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Mar 13, 2024 21:12
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TooMuchAbstraction posted:My Pixel 3 phone no longer accepts being plugged into my car. It can still access the audio system over bluetooth, but it can't charge or show navigation on the car's main display. I assume this is down to the phone's USB-C port degrading with age, since the connection was kinda crotchety for awhile, and I've tried using a different cable to no avail. Similarly, cleaning out the port with air from a squeeze bulb hasn't helped.
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Apr 26, 2024 06:19
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Mister Speaker posted:I opened a beer can that had been bouncing around in my bag and had a weird train of thought, from a really dumb question to one or two that aren't so dumb. Avoiding any gas space would be hard to do. The solubility of gases in liquids depends on temperature (more gas dissolves when cold) and pressure (more gas dissolves under higher pressure). The cans are filled with very cold liquid and high CO2 pressures. Even if you completely filled it with liquid initially, some gas would come out of solution if it warmed up at all. But if you did manage no/little gas space so that there were no tiny bubbles when you shook it, it wouldn't explode if you opened it afterwards Mister Speaker posted:But that got me thinking of fluid dynamics, I guess. Liquids cannot be compressed but gases can, right? So yeah, that second question again but about a theoretical container whose entire volume is 100% absolutely full of some inert fluid like water, what's going on in there when the container is moved around? Molecules will certainly be moving about but would there be any momentum to it, like the sloshing when you shake a half-full bottle of something?  ) if you had a completely full water bottle and then added a drop of food coloring, then capped it. The color will slowly diffuse through it, and if you shake it, it will spread faster.Mister Speaker posted:But that got me thinking of fluid dynamics, I guess. Liquids cannot be compressed but gases can, right? So yeah, that second question again but about a theoretical container whose entire volume is 100% That all sounds very dumb and yes I was (and am) high but it ended up in a more general question about using fluids to do work: Why do we use both hydraulic and pneumatic systems, and in what situations are either more appropriate? The main advantage for hydraulics is that it's much easier to make a high pressure pump for incompressible fluids, so you can have a much higher working pressure and transfer more power more easily. 10,000psi working pressure is common in hydraulic systems, pneumatics are more typically around 70-100
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Apr 30, 2024 03:47
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