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Pittsburgh Fentanyl Cloud
Apr 7, 2003


A Bag of Milk posted:

Hmmm I wonder why there's no evidence, and what could possibly be done to change that. Oh well

We cannot let fear limit the milk market. Drink milk to help out.

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Pittsburgh Fentanyl Cloud
Apr 7, 2003


Odds are very good that this h5n1 eruption will burn out before it causes human deaths, but I'm lolling at how they're spinning up the Covid playbook in anticipation anyway. We're not getting public health ever again.

Platystemon
Feb 13, 2012

BREADS

Platystemon posted:

I mean, I think that more likely than not monkeypox doesn’t go pandemic, but everyone with power softpedaling the thing is exactly how we get pandemics, soooo…

Steve Yun
Aug 7, 2003
I'm a parasitic landlord that needs to get a job instead of stealing worker's money. Make sure to remind me when I post.
Soiled Meat
I must not fear. Fear is the mood-killer. Fear is the little-death that brings back lock downs. I will dodge my fear. I will permit myself to ignore it. And when it has gone past I will turn the inner eye to see its path. Where the fear has gone there will be nothing. Only living my life will remain.

Platystemon
Feb 13, 2012

BREADS


Lockdown [2020–present, colorized]

maxwellhill
Jan 5, 2022
we've been locked inside our homes for far too long because of all these cows!!

Cup Runneth Over
Aug 8, 2009

She said life's
Too short to worry
Life's too long to wait
It's too short
Not to love everybody
Life's too long to hate


Platystemon posted:



Lockdown [2020–present, colorized]

Only servants and other poors wearing masks, it checks out

Platystemon
Feb 13, 2012

BREADS

quote:



That's been running about 3 months and due for a change. It moves a huge volume of air compared to those little air purifiers and you can prop it up in a corner, and the filters are a huge value since it's not some proprietary size.

Some loving college hipsters tried to say they invented it during covid just because they did the same thing and taped 4 filters into a cube shape, but that just makes the whole thing take up 4x the space. They just wanted to put their dumb names on something. Mine works fine!

spiritual bypass
Feb 19, 2008

Grimey Drawer

unironically this and i had one way before covid appeared

NeonPunk
Dec 21, 2020



Lmao, reeeeaaallly hoping it's just the regular flu

Cabbages and VHS
Aug 25, 2004

Listen, I've been around a bit, you know, and I thought I'd seen some creepy things go on in the movie business, but I really have to say this is the most disgusting thing that's ever happened to me.

The Oldest Man posted:

wild, i would not have guessed that increased co2 makes the virus more physically stable

all these fun things about co2 we’re finding out

imagine what else we don’t know, yet :allears:

Strep Vote
May 5, 2004

أنا أحب حليب الشوكولاتة
Neat! Interesting that the kidneys and lungs, two of the most prominent sites for co2 and ph balance get wrecked.

I'm not freaking about milk because if it's already in 30%ish of the supply we would have seen mysterious sickness all over already.

Potato Salad
Oct 23, 2014

nobody cares


mawarannahr posted:

timely analysis from the boys down at the shop, headed by Rudolf Henkell-von Ribbentrop.

food safety is the number one concern and ranks as the fifth in list of concerns:




What is top of mind for dairy executives in 2024?

Lol they TOTALLY WORRY ABOUT BARRIERS FOR NEW ENTRANTS, its the NEW ENTRANTS they are worried about, please understand we are concerned for PLUCKY STARTUP REAL AMERICAN ENTREPRENEURS, that's who regulation REALLY hurts, please do NOT regulate me

Potato Salad
Oct 23, 2014

nobody cares


The Oldest Man posted:

wild, i would not have guessed that increased co2 makes the virus more physically stable

need to read the study because, trivially, co2 and covid are both downstream of "poor air quality" and it really could just be as simple as "you're breathing air from infected peoples lungs"

Potato Salad
Oct 23, 2014

nobody cares


mawarannahr posted:

timely analysis from the boys down at the shop, headed by Rudolf Henkell-von Ribbentrop.

food safety is the number one concern and ranks as the fifth in list of concerns:




What is top of mind for dairy executives in 2024?

Lol I can't stop rereading this. This is what the blind leading the blind looks like.

"3. Demand - How do we go where the market is headed?" WELL I DON'T KNOW GUYS, LOOKS LIKE FOOD SAFETY IS CONCERN #1 FOR CONSUMERS, MAYBE YOU'RE NOT ALIGNED WITH THE MARKET HERE PLACING FOOD SAFETY AT THE BOTTOM.

"1. Sustainability" aahahahhahahahaha "idk guys maybe we need more subsidies, there's 'so many variables' with 'sustainability' in dairy" comes across as an effort to beg for even higher direct or indirect subsidies for cattle

Potato Salad
Oct 23, 2014

nobody cares


American agribiz prefers command economy communism, unironically. Change my mind.

tuyop
Sep 15, 2006

Every second that we're not growing BASIL is a second wasted

Fun Shoe

Potato Salad posted:

American agribiz prefers command economy communism, unironically. Change my mind.

technically I think we have a dictatorship of the bourgeoisie rather than the proletariat, but yeah I guess it’s basically a sort of socialism but inverted.

NeonPunk
Dec 21, 2020

Strep Vote posted:

I'm not freaking about milk because if it's already in 30%ish of the supply we would have seen mysterious sickness all over already.

Insert a huge Yet in there. I am really concerned because it just need a few mutations and it'll will easily just take off in humans.

With how difficult it is to get the genome data from USDA, we're not going to get any updates on any mutations that happens until we find out after the fact.

tuyop
Sep 15, 2006

Every second that we're not growing BASIL is a second wasted

Fun Shoe

Strep Vote posted:

Neat! Interesting that the kidneys and lungs, two of the most prominent sites for co2 and ph balance get wrecked.

I'm not freaking about milk because if it's already in 30%ish of the supply we would have seen mysterious sickness all over already.

I guess what are you expecting to see when it pops off? how do you think you’ll know?

this is a serious question. it’s clear that the data will not be forthcoming from our institutions so we should discuss other ways of detecting this.

mags
May 30, 2008

I am a congenital optimist.

it is very fun how often this thread and biosphere collapse overlap

Teabag Dome Scandal
Mar 19, 2002


mags posted:

it is very fun how often this thread and biosphere collapse overlap

Its funny you should mention the biosphere collapse. I found a thread by a guy who helped write the paper and in it he mentions the increase in ambient CO2 may be contributing.
https://x.com/ukhadds/status/1783750076105384279
very long thread but very interesting. one thing I can't remember seeing much discussion of is he talks about the stability of different strains and how omicron was more stable than delta.

Teabag Dome Scandal has issued a correction as of 16:43 on Apr 26, 2024

Gunshow Poophole
Sep 14, 2008

OMBUDSMAN
POSTERS LOCAL 42069




Clapping Larry

Potato Salad posted:

American agribiz prefers command economy communism, unironically. Change my mind.

occasionally I look back at the farmers i worked with doing my master's degree and try to make their numbers work without huge vouchsafed gambling on behalf of the government

corn price is down 35% in like 2 years lol

wheat also like 210 a bushel and that poo poo is insanely labor intensive

and it all. goes. into. COWS babyyyy

Strep Vote
May 5, 2004

أنا أحب حليب الشوكولاتة

tuyop posted:

I guess what are you expecting to see when it pops off? how do you think you’ll know?

this is a serious question. it’s clear that the data will not be forthcoming from our institutions so we should discuss other ways of detecting this.

Think about it. It's already detectable in 20% of the milk supply at the least (according to the FDA). How many people in America drink milk daily? If it were infectious in the milk it would have already acted like a food borne illness and hit a lot of people all at once all over.

I'd expect outbreak of mysterious illness concentrated in children (the biggest milk drinkers) nationwide if it were going to be a problem.

U-DO Burger
Nov 12, 2007




Strep Vote posted:

Think about it. It's already detectable in 20% of the milk supply at the least (according to the FDA). How many people in America drink milk daily? If it were infectious in the milk it would have already acted like a food borne illness and hit a lot of people all at once all over.

I'd expect outbreak of mysterious illness concentrated in children (the biggest milk drinkers) nationwide if it were going to be a problem.

I am leaning towards this, but imo it's also possible pasteurization gets the vast majority of the virus, but not all, resulting in far less widespread illness (assuming the remaining virus is infectious)

The Oldest Man
Jul 28, 2003

Potato Salad posted:

need to read the study because, trivially, co2 and covid are both downstream of "poor air quality" and it really could just be as simple as "you're breathing air from infected peoples lungs"

Yeah you should read the study lol

The Oldest Man
Jul 28, 2003

Pittsburgh Fentanyl Cloud posted:

Odds are very good that this h5n1 eruption will burn out before it causes human deaths, but I'm lolling at how they're spinning up the Covid playbook in anticipation anyway. We're not getting public health ever again.

Strep Vote posted:

Think about it. It's already detectable in 20% of the milk supply at the least (according to the FDA). How many people in America drink milk daily? If it were infectious in the milk it would have already acted like a food borne illness and hit a lot of people all at once all over.

I'd expect outbreak of mysterious illness concentrated in children (the biggest milk drinkers) nationwide if it were going to be a problem.

Increasing the contact area between HPAI and human flesh is an incredibly bad thing and the potential for the virus to be in the milk supply is another three or four order of magnitude increase in that contact area

The problem isn't that the gently caress Us Up strain is hiding somewhere waiting to get us. H5N1 isn't a fully human-adapted virus yet. The problem is that we're actively creating a bioreactor out of the entire food supply that will eventually create the gently caress Us Up strain. It's like hugging and kissing a bat, except billions of times every day.

Strep Vote
May 5, 2004

أنا أحب حليب الشوكولاتة

The Oldest Man posted:

Increasing the contact area between HPAI and human flesh is an incredibly bad thing and the potential for the virus to be in the milk supply is another three or four order of magnitude increase in that contact area

The problem isn't that the gently caress Us Up strain is hiding somewhere waiting to get us. H5N1 isn't a fully human-adapted virus yet. The problem is that we're actively creating a bioreactor out of the entire food supply that will eventually create the gently caress Us Up strain. It's like hugging and kissing a bat, except billions of times every day.

It's not infectious via ingestion (edit ~YET~ but influenza is famous for loving ur lungs the most), that protein is getting denatured and hosed up by your stomach acid before it can even touch your flesh. I'm guessing the cows are inhaling infectious agents straight from the litter and getting infected that way. A dairy worker had an eye infection--that's probably from air or direct contact with infected material. Right now I would be handing out auras and goggles to dairy workers and monitoring the situation for further developments. e2: And making them wash their hands since its probably floating all over due to the feed.

Strep Vote has issued a correction as of 18:10 on Apr 26, 2024

Snowglobe of Doom
Mar 30, 2012

sucks to be right
Also the fact that h5n1 is already so massively widespread in one specific kind of domestic mammal but the only indicator we have is extremely indirect should be a gigantic concern all on its own. How many other domestic or wild mammal species has this spread to? How far is that spread? Are they only going to get a little sniffly and listless like these infected cows seem to have become, or are all those dead barn cats an indicator that some species are going to be hosed?

The Oldest Man
Jul 28, 2003

Strep Vote posted:

It's not infectious via ingestion (edit ~YET~ but influenza is famous for loving ur lungs the most), that protein is getting denatured and hosed up by your stomach acid before it can even touch your flesh. I'm guessing the cows are inhaling infectious agents straight from the litter and getting infected that way. A dairy worker had an eye infection--that's probably from air or direct contact with infected material. Right now I would be handing out auras and goggles to dairy workers and monitoring the situation for further developments.

Consumption of dead HPAI-afflicted sea birds is implicated in those mass sea lion die-offs last January. Did they get it via inhalation during the process of eating the birds, via the GI tract, or via some chance encounter with a bird coughing on them before it died? No one knows. All I know is that providing a highly lethal virus that already has some capability to infect humans with a few billion more chances to figure us out is going to result, ultimately, in it figuring us out.

Snowglobe of Doom posted:

Also the fact that h5n1 is already so massively widespread in one specific kind of domestic mammal but the only indicator we have is extremely indirect should be a gigantic concern all on its own. How many other domestic or wild mammal species has this spread to? How far is that spread? Are they only going to get a little sniffly and listless like these infected cows seem to have become, or are all those dead barn cats an indicator that some species are going to be hosed?

Yeah it's just one flashing warning sign after another.

Oracle
Oct 9, 2004

tuyop posted:

I guess what are you expecting to see when it pops off? how do you think you’ll know?

this is a serious question. it’s clear that the data will not be forthcoming from our institutions so we should discuss other ways of detecting this.

remembering the outbreak of pinkeye this past winter being an apparent new symptom of JN.1 but maybe it was flu instead/too?
oh and diarrhea!

Oracle has issued a correction as of 18:22 on Apr 26, 2024

Strep Vote
May 5, 2004

أنا أحب حليب الشوكولاتة

The Oldest Man posted:

Consumption of dead HPAI-afflicted sea birds is implicated in those mass sea lion die-offs last January. Did they get it via inhalation during the process of eating the birds, via the GI tract, or via some chance encounter with a bird coughing on them before it died? No one knows.

I'm 99% convinced it's bird poo poo that transmits it. Those sea lions and those beaches are covered in bird poo poo, it gets everywhere and I wouldn't be surprised if they ingest it or inhale it directly.

quote:

Another possible explanation for HPAIV H5N1 transmission could be the consumption of positive sick avian species. This hypothesis was previously proposed by Gamarra et al. in Peru after documenting an SA sea lion catching a seabird (Gamarra-Toledo et al. 2023). This mode of transmission has also been suggested in other mammals affected by HPAIV H5N1 (Krammer and Schultz-Cherry 2023), and thus cannot be fully discarded. However, it may not account for all the cases due to the high number of infections, and it is not a common behavior for SA sea lions to feed on carcasses of dead birds. In both scenarios, the high presence of HPAIV H5N1 in avian is needed which was effectively demonstrated in the figure spatial analysis (Figure 3). Additionally, it is important to mention that the most likely route of virus entry is through the digestive system, which requires further investigation as well.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588531/

It just doesn't make a whole lot of sense. I think the bird droppings are implicated in the dairy outbreaks and in wild outbreaks.

Snowglobe of Doom
Mar 30, 2012

sucks to be right
Don't forget that it's also getting passed back to birds via cows, so maybe cow excrement is also a vector

NeonPunk posted:

They also found some mutations in birds nearby that were traced to be from cows themselves. It's definitely airborne.

The Oldest Man
Jul 28, 2003

Strep Vote posted:

I'm 99% convinced it's bird poo poo that transmits it. Those sea lions and those beaches are covered in bird poo poo, it gets everywhere and I wouldn't be surprised if they ingest it or inhale it directly.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588531/

It just doesn't make a whole lot of sense. I think the bird droppings are implicated in the dairy outbreaks and in wild outbreaks.

If HPAI doesn't colonize the GI tract then how's it getting into the bird poo poo in the quantities required to be infectious in the first place

e: to be clear here, I'm not saying the PCR positives in the milk supply prove there's viable, infectious virus. im also not saying drinking milk that contains viable infectious virus would necessarily infect a human. what i am saying is that we've gone from maybe like hundreds or thousands of HPAI/human contact events per day to millions or maybe billions in the span of a couple years. it ultimately doesn't matter whether it's cow farts, milk, eggs, chicken poop being used as fertilizer or whatever that ferry the virus into contact with a host cell since the contact area between all of those and humans is massive compared to the contact area between humans and wild birds was a few years ago. the law of large numbers is going to have its say here one way or another.

The Oldest Man has issued a correction as of 18:39 on Apr 26, 2024

Strep Vote
May 5, 2004

أنا أحب حليب الشوكولاتة
^^^ i think we're in agreement on this, I just don't see what I would expect to see if this were an immediate problem. It's more of an intermediate problem that we should get to work on immediately.

The Oldest Man posted:

If HPAI doesn't colonize the GI tract then how's it getting into the bird poo poo in the quantities required to be infectious in the first place

Good question. It's detectible in human wastewater too and doesn't colonize our GI tract. I actually don't know if we know that flu absolutely never transmits via fecal oral route, just that its preferred pathway is lung epithelial tissue. Here's the first thing I found that's interesting:

quote:

There is very little evidence to suggest that the faecal‐oral or waterborne route of transmission occurs in humans, in contrast to transmission that occurs amongst birds.10, 11

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909391/

:shrug: time to find out i guess! But I don't see any initial cause for alarm. That said, cut dairy if you like, the plant based butter is pretty good.

Strep Vote has issued a correction as of 18:49 on Apr 26, 2024

The Oldest Man
Jul 28, 2003

I'll just stick to UHT milk products

Strep Vote posted:

I actually don't know if we know that flu absolutely never transmits via fecal oral route, just that its preferred pathway is lung epithelial tissue.

Writing a grant where I expose the entire American population to HPAI via the oral route to find out just how preferred "preferred" is

Strep Vote
May 5, 2004

أنا أحب حليب الشوكولاتة

The Oldest Man posted:

I'll just stick to UHT milk products

Writing a grant where I expose the entire American population to HPAI via the oral route to find out just how preferred "preferred" is

I guess we will find out. I hope it stays preferred, tbh, I love milk.

The Oldest Man
Jul 28, 2003

Strep Vote posted:

I guess we will find out. I hope it stays preferred, tbh, I love milk.

I have a lot more faith in ultra-pasteurization than I do in a virus that seems to be able to infect and kill any type of bird or mammal to obey the respiratory-not-GI-mucosa NAP

Strep Vote
May 5, 2004

أنا أحب حليب الشوكولاتة

The Oldest Man posted:

I have a lot more faith in ultra-pasteurization than I do in a virus that seems to be able to infect and kill any type of bird or mammal to obey the respiratory-not-GI-mucosa NAP

I agree, but I think a fecal respiratory route is more likely to emerge in dairy workers, and then human to human transmission. Like hantavirus :unsmigghh:

sonatinas
Apr 15, 2003

Seattle Karate Vs. L.A. Karate
well the only(to my knowledge)us produced iota carrageenan spray is no more I guess because the website for Nasitrol gets redirected to some scam site.

guess keep on importing Flo.

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Steve Yun
Aug 7, 2003
I'm a parasitic landlord that needs to get a job instead of stealing worker's money. Make sure to remind me when I post.
Soiled Meat
https://x.com/bnofeed/status/1783907330519609694?s=46

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