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xPanda
Feb 6, 2003

Was that me or the door?

Laserface posted:

Im pretty certain the only reason Codeine is sold with paracetamol/Ibuprofen is because Codeine is way better for you and does a better job (while also being addictive if abused) so they put it with something else that might kill you if you have too much of it to try and prevent people doing so.

and look how that worked out.

The dose of codeine is sub therapeutic for pain relief, but high enough for constipation. I can't believe the paracetamol and ibuprofen would be put there as a deterrent, it's unethical as poo poo, liver and kidney failure is rather extreme. More likely they made a bad call in permitting this formulation, and we now know better.

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Birb Katter
Sep 18, 2010

BOATS STOPPED
CARBON TAX AXED
TURNBULL AS PM
LIBERALS WILL BE RE-ELECTED IN A LANDSLIDE

xPanda posted:

The dose of codeine is sub therapeutic for pain relief, but high enough for constipation. I can't believe the paracetamol and ibuprofen would be put there as a deterrent, it's unethical as poo poo, liver and kidney failure is rather extreme. More likely they made a bad call in permitting this formulation, and we now know better.

I'm pretty sure I specifically remember them saying that companies were required to do this so that people couldn't abuse the drug. As in that is the whole reason it happened in the first place.

break-up breakdown
Mar 6, 2010

there's been some research to suggest codeine and paracetamol can be effective when used together to treat pain, but absolutely the main reason they're sold otc together is so people can have access to codeine while making it difficult to abuse (without damaging your liver with the paracetamol). It's a dumbass system that has definitely caused more harm than preventing a few junkies getting their fix would ever be worth.

legalise all drugs

Unimpressed
Feb 13, 2013

This is all very silly. No one put paracetamol and ibuprofen in codeine to make it dangerous. Both paracetamol and ibufprofen are effective in treating common low level pain. Oh and paracetamol is not an NSAID. A lot of bullshit being thrown around in this argument with very little relation to fact.

Cleretic
Feb 3, 2010


Ignore my posts!
I'm aggressively wrong about everything!

Oh man, this just made me realize how dangerous Abbott is right now. He was relentless and dangerous as opposition leader, never letting the fact he had no facts get in the way, and he was remarkably effective at it.

Now he's back out of power. And clearly holding a grudge.

Vladimir Poutine
Aug 13, 2012
:madmax:

xPanda posted:

The dose of codeine is sub therapeutic for pain relief, but high enough for constipation. I can't believe the paracetamol and ibuprofen would be put there as a deterrent, it's unethical as poo poo, liver and kidney failure is rather extreme. More likely they made a bad call in permitting this formulation, and we now know better.

It is put in as a deterrent. Codeine + paracetamol/ibuprofen is schedule 3, which means it's OTC. Codeine only is Schedule 8, which means they need a prescription and often need to be authorised by a specialist.

quote:

Schedule 8 (S8) drugs and poisons, otherwise known as 'Controlled Drugs', are substances and preparations for therapeutic use which have high potential for abuse and addiction.

Amoeba102
Jan 22, 2010

Paracetamol and Ibuprofen were mixed with codeine so second year chemistry students could do acid/base extractions as lab experiments.

Birb Katter
Sep 18, 2010

BOATS STOPPED
CARBON TAX AXED
TURNBULL AS PM
LIBERALS WILL BE RE-ELECTED IN A LANDSLIDE

Amoeba102 posted:

Paracetamol and Ibuprofen were mixed with codeine so second year chemistry students could do acid/base extractions as lab experiments.

Couldn't they just go to bush doofs. It's how normal people get their acid and bass experiments done.

Eediot Jedi
Dec 25, 2007

This is where I begin to speculate what being a
man of my word costs me


No speedos 0/10.

Actually it's beautiful and I think the baby Bernardi is nursing is a nod towards him splitting off to form his own new party.


Cleretic posted:

Oh man, this just made me realize how dangerous Abbott is right now. He was relentless and dangerous as opposition leader, never letting the fact he had no facts get in the way, and he was remarkably effective at it.

Now he's back out of power. And clearly holding a grudge.

Yeah he was dangerous because hardly anyone called him on his bullshit and as opposition leader he had no real responsibilities other than to kick, scream and point fingers which is what he does best. I am so hoping he does more of this "I'm not complain but..." or "I'm not sniping but..." The cutest part about it is I think Abbott is so dumb he doesn't actually realize he's sniping. He's the kind of person that thinks prefacing a sentence with, "No offense intended but" actually means something.

Unimpressed
Feb 13, 2013

I thought that was Kevin Andrews nursing the baby.

Amoeba102
Jan 22, 2010

Yeah gotta be Andrews, check the hair and ears.

Inge
Jan 16, 2007
SERIOUSLY THATS DISGUSTING I'M TRYING TO EAT

xPanda posted:

The dose of codeine is sub therapeutic for pain relief, but high enough for constipation. I can't believe the paracetamol and ibuprofen would be put there as a deterrent, it's unethical as poo poo, liver and kidney failure is rather extreme. More likely they made a bad call in permitting this formulation, and we now know better.

You know I've always wondered why they even bother with 500mg / 8mg preparations. Not too sure about any synergystic effects between the two.

Also, are you a pharmacist? The dosage instructions on tablet packets seem to be kind of dumb. Who are they for? Because I imagine there's some standard model, and the analgesic dosage for a 50kg person is probably not the same as a 90kg person.

On a lot of baby medicines they have a mL / kilogram kind of thing going on, which seems like a better way to dose (something like one tablet per 30kgs body weight). Why don't they do this?

Genuinely curious about this.

Anecdotally, if I use codeine at all, I have 3 tablets of 12.8mg and 1.5g paracetamol which seems to work quite well, better than 2 tablets or paracetamol alone (maybe placebo?), and my GP seemed ok with it.

CATTASTIC
Mar 31, 2010

¯\_(ツ)_/¯

Tommofork posted:

Yeah he was dangerous because hardly anyone called him on his bullshit and as opposition leader he had no real responsibilities other than to kick, scream and point fingers which is what he does best.

Once the Murdoch press is over it's conniption they'll either have to start pointing out his bullshit or let him undermine the LNP.

Eediot Jedi
Dec 25, 2007

This is where I begin to speculate what being a
man of my word costs me

Unimpressed posted:

I thought that was Kevin Andrews nursing the baby.

Amoeba102 posted:

Yeah gotta be Andrews, check the hair and ears.

I'm not entirely convinced, I'd need to study Pope's depictions of Andrews/Bernardi in his previous works. But you're both way more likely to be right given that Andrews and Abetz got booted from their portfolios and I'm just being dumb.

QUACKTASTIC posted:

Once the Murdoch press is over it's conniption they'll either have to start pointing out his bullshit or let him undermine the LNP.

I never thought I'd say this but you should read Bolt's subarticle from the Herald Sun yesterday. He goes off his nut that the ABC must be feeling safe with Turnbull in charge, and specifically goes after Q&A because they had three left wing and two right wing panelists according to Bolt, and because Tony Jones remarked that people are speculating that Bernardi would form his own party, and jokingly called it, "Cory Bernardi’s Golden Dawn". And wow does he cry a lot.

Unimpressed
Feb 13, 2013

Inge posted:

You know I've always wondered why they even bother with 500mg / 8mg preparations. Not too sure about any synergystic effects between the two.

Also, are you a pharmacist? The dosage instructions on tablet packets seem to be kind of dumb. Who are they for? Because I imagine there's some standard model, and the analgesic dosage for a 50kg person is probably not the same as a 90kg person.

On a lot of baby medicines they have a mL / kilogram kind of thing going on, which seems like a better way to dose (something like one tablet per 30kgs body weight). Why don't they do this?

Genuinely curious about this.

Anecdotally, if I use codeine at all, I have 3 tablets of 12.8mg and 1.5g paracetamol which seems to work quite well, better than 2 tablets or paracetamol alone (maybe placebo?), and my GP seemed ok with it.

The dosing has a big safety margin built into it. Last time we went overseas, we were in Spain and bought some generic Ibuprofen. It came as single 600mg pills which is 1.5 times the recommended 2x200mg dose we have here. I asked my wife (she's the one who actually knows what I'm writing about) and she said it was perfectly safe. Also, most medication is given using ml/kg in a hospital setting but it's deemed too hard for the general population. There's no choice but to do it with babies since there's such a huge variance in weights (i.e. a 90kg person weighs only about 30% more than a 70kg person, but a 10kg baby is twice the weight of a 5kg one and that difference can happen in a few months not to mention it's a baby. Fact is that even with those safety margins, paracetamol overdoses are common and in many cases life threatening.

Divorced And Curious
Jan 23, 2009

democracy depends on sausage sizzles

Cleretic posted:

Oh man, this just made me realize how dangerous Abbott is right now. He was relentless and dangerous as opposition leader, never letting the fact he had no facts get in the way, and he was remarkably effective at it.

Now he's back out of power. And clearly holding a grudge.

we call this "doing a Rudd"


Gillard lasted three years, be interesting to see how long Turnbull can hold on for

Cartoon
Jun 20, 2008

poop

Anidav posted:

Lmao the Australian Border Force logo and flags are all over Brisbane International Airport. Are they the A-Team or something?
Pics or it didn't happen.

HookShot posted:

Did you have to go through separate, extra security in Brisbane where they re-scan all of your laptops and poo poo a second, more annoying time because BORDER FORCE like they do at Coolangatta?
I'm so over this air transport theatre. The amount of deaths I could cause with a chain saw or an oxy torch on the train network would rival any plane crash but hey! Too hard to do anything about that so let's just roll with a bit of circus at the airports. So very, very productive.

Speaking of productivity. Remember kiddies everytime a muppet like Westacott bleats about increasing productivity :



Well that and the most clearly obvious way to drastically improve productivity in Australia is to improve the performance of executives, middle managers and managers. Full details here: https://thisisseriouscom.wordpress.com/2012/12/06/the-gist/

-/-

Now I don't think we can look forward to another LNP face plant like last month to save this thread so can we please try to keep a little signal inside the noise? tia.

http://www.abc.net.au/news/2015-10-02/cassidy-abbotts-self-indulgent-and-damaging-farewell-radio-tour/6820304

The flames are all long gone
But the pain lingers on

http://www.theaustralian.com.au/news/latest-news/cut-abbott-some-slack-cormann/story-fn3dxiwe-1227553364313

quote:

Cut Abbott some slack: Cormann AAP OCTOBER 02, 2015 8:22AM

A senior colleague denies former leader Tony Abbott is starting to destabilise the government. ONE of Tony Abbott's senior colleagues believes people should cut the former prime minister some slack. THE deposed Liberal leader took to radio again on Thursday declaring he always knew Malcolm Turnbull didn't want to be somebody else's minister, at the same time as his successor was hosting a mini-economic summit.

Finance Minister Mathias Cormann denied Mr Abbott was starting to destabilise the government, telling ABC radio on Friday: "I think that we all should just cut him a bit of slack". EDIT - Corrupt Cabinet secretary Arthur Sinodinos offered up the advice given to John Howard in 1989 and Mr Turnbull in 2009 when they contemplated whether to leave politics. "If you feel you've still got a contribution to make to politics, by all means do so," he told Mr Abbott via ABC radio. "If you leave politics feeling you haven't fulfilled your potential or everything you could have done, that is a worse feeling."
:qq: :qq: :qq:

"I want to see those ashen-faced performances; I want more of them. I want to be encouraged. I want to see you squirm out of this load of rubbish over a number of months." :smith: I shouldn't be getting such a kick out of this should I.

open24hours
Jan 7, 2001

SeekOtherCandidate posted:

we call this "doing a Rudd"


Gillard lasted three years, be interesting to see how long Turnbull can hold on for

Rudd was reasonably popular though. No one likes Abbott except for people like Abbott, who are a minority in the public and in the party. After Rudd was knifed everyone seemed a bit shocked, they just seem relieved this time.

Inge
Jan 16, 2007
SERIOUSLY THATS DISGUSTING I'M TRYING TO EAT

Unimpressed posted:

The dosing has a big safety margin built into it. Last time we went overseas, we were in Spain and bought some generic Ibuprofen. It came as single 600mg pills which is 1.5 times the recommended 2x200mg dose we have here. I asked my wife (she's the one who actually knows what I'm writing about) and she said it was perfectly safe. Also, most medication is given using ml/kg in a hospital setting but it's deemed too hard for the general population. There's no choice but to do it with babies since there's such a huge variance in weights (i.e. a 90kg person weighs only about 30% more than a 70kg person, but a 10kg baby is twice the weight of a 5kg one and that difference can happen in a few months not to mention it's a baby. Fact is that even with those safety margins, paracetamol overdoses are common and in many cases life threatening.

Yeah I totally get that, and maybe I'm putting too much faith in the basic arithmetic skills of Australians.

xPanda
Feb 6, 2003

Was that me or the door?

Unimpressed posted:

The dosing has a big safety margin built into it. Last time we went overseas, we were in Spain and bought some generic Ibuprofen. It came as single 600mg pills which is 1.5 times the recommended 2x200mg dose we have here. I asked my wife (she's the one who actually knows what I'm writing about) and she said it was perfectly safe. Also, most medication is given using ml/kg in a hospital setting but it's deemed too hard for the general population. There's no choice but to do it with babies since there's such a huge variance in weights (i.e. a 90kg person weighs only about 30% more than a 70kg person, but a 10kg baby is twice the weight of a 5kg one and that difference can happen in a few months not to mention it's a baby. Fact is that even with those safety margins, paracetamol overdoses are common and in many cases life threatening.
Ha, I'm in the same boat in that it's my partner who is the pharmacist, but I'm in a situation where I'm around research pharmacists all day, so I pick up a lot. The above is what I would have said, but I'd add that it's much easier to overdose and injure yourself with paracetemol than it is ibuprofen. At least in one pattern of overdose - it's a complex thing. I think/guess the calibration of doses for ibuprofen in this case is probably because people had the prior knowledge that "you take two painkiller pills" from previously available medications and so they aped that to hopefully reduce the incidence of therapeutic errors.

Inge posted:

Yeah I totally get that, and maybe I'm putting too much faith in the basic arithmetic skills of Australians.

Yeah, you wouldn't believe how many people poison their children when they have to measure stuff for the child's weight. I doesn't seem to always be poor arithmetic skills, sometimes it's confusing measuring instruments. I'm shocked at how many syringes simply have unit-less numbers as their measure, and the "full" volume of the syringe written somewhere else on it. For instance, I've seen 3mL synringes with markings which are simply integers from 1 to 10. My scientific training makes me think that the markings are tenths of 3mL (a stupid interval) but the public will look at it and see intervals of 1mL - which is exactly in line with their prior experience. Stuff like that is why what is called 'pharmacy practice' is so important, because all the science in the world is useless if people can't use it. It's unfortunate that so many researchers look down on it, because it can have such a large impact on quality of care.

Also, I hope everyone keeps in mind that pharmacists are the people who prevent doctors from killing you with drugs. Pharmacists learn for years what doctors spend a semester on, so they're absolutely essential. All moves to turn pharmacies into shopping markets must be resisted - Chemists Warehouse is the one of the worst things to happen to the industry in recent times. When a pharmacist has to process a script every 20 seconds they won't be able to provide the counseling that is needed.

Starshark
Dec 22, 2005
Doctor Rope
Post your favorite Abbott quotes ITT. I can't find mine, but it's the one where he refers to carbon dioxide as a "invisible, odourless, weightless, tasteless substance".

open24hours
Jan 7, 2001

https://www.youtube.com/watch?v=MA-zsXRJw0M

Lid
Feb 18, 2005

And the mercy seat is awaiting,
And I think my head is burning,
And in a way I'm yearning,
To be done with all this measuring of proof.
An eye for an eye
And a tooth for a tooth,
And anyway I told the truth,
And I'm not afraid to die.

open24hours posted:

Rudd was reasonably popular though. No one likes Abbott except for people like Abbott, who are a minority in the public and in the party. After Rudd was knifed everyone seemed a bit shocked, they just seem relieved this time.

Labor tried too hard to protect Rudd that the public never saw his failures. Malcolm was smart enough to give Abbott enough rope to hang himself.

Negligent
Aug 20, 2013

Its just lovely here this time of year.
"No one, however smart, however well educated, however experienced, is the suppository of all wisdom."

You Am I
May 20, 2001

Me @ your poasting

Starshark posted:

Post your favorite Abbott quotes ITT. I can't find mine, but it's the one where he refers to carbon dioxide as a "invisible, odourless, weightless, tasteless substance".

"Good government starts today"

Cartoon
Jun 20, 2008

poop
"The adults are back in charge."

Divorced And Curious
Jan 23, 2009

democracy depends on sausage sizzles
"Good morning sir, how are you?"

dr_rat
Jun 4, 2001

You Am I posted:

"Good government starts today"

Wait was he talking about today? Oh god no wonder he was so hopeless, he was ousted merer days before good government started.

The ironiony.

Halo14
Sep 11, 2001

Yep, sociopath.

Zenithe
Feb 25, 2013

Ask not to whom the Anidavatar belongs; it belongs to thee.
"What the housewives of Australia need to understand as they do the ironing..."
"a little body contact’ never hurt anyone" (to a group of young netball playing women)
"Jesus knew that there was a place for everything and it’s not necessarily everyone’s place to come to Australia."

HookShot
Dec 26, 2005
"A bad boss is a bit like a bad husband or bad father..."

freebooter
Jul 7, 2009

"poo poo happens."

MonoAus
Nov 5, 2012

Starshark posted:

Post your favorite Abbott quotes ITT. I can't find mine, but it's the one where he refers to carbon dioxide as a "invisible, odourless, weightless, tasteless substance".

"ermmm uhhhuh aahhhuh aaaaaaaah mmmmmee"

Starshark
Dec 22, 2005
Doctor Rope

MonoAus posted:

"ermmm uhhhuh aahhhuh aaaaaaaah mmmmmee"

Only, because it's Tony we're talking about here, it goes: "ermmm uhhhuh aahhhuh aaaaaaaah mmmmmee. ermmm uhhhuh aahhhuh aaaaaaaah mmmmmee.ermmm uhhhuh aahhhuh aaaaaaaah mmmmmee."

MonoAus
Nov 5, 2012
mmmmm ahhhhhmmhmmmm *licks lips* mhmmammahhhamm rmmmm*lick*

GoldStandardConure
Jun 11, 2010

I have to kill fast
and mayflies too slow

Pillbug

Starshark posted:

Post your favorite Abbott quotes ITT. I can't find mine, but it's the one where he refers to carbon dioxide as a "invisible, odourless, weightless, tasteless substance".

*silently bobbleheads for sixty seconds*

Don Dongington
Sep 27, 2005

#ideasboom
College Slice
"Well I guess poo poo happens..."

Edit E;F;B

tithin
Nov 14, 2003


[Grandmaster Tactician]



I'm not contributing anything because the man was a monster, an ideologue, a zealot and someone who was so brittle he could not bend.

I genuinely hope he continues to shoot down the government and becomes the worlds biggest hypocrite before somehow shooting himself in the back of the head six times, sticking his own body into a bag and chucking himself into the river.

Doctor Spaceman
Jul 6, 2010

"Everyone's entitled to their point of view, but that's seriously a weird one."

Starshark posted:

Post your favorite Abbott quotes ITT. I can't find mine, but it's the one where he refers to carbon dioxide as a "invisible, odourless, weightless, tasteless substance".

quote:

"I know politicians are going to be judged on everything they say, but sometimes in the heat of discussion you go a little bit further than you would if it was an absolutely calm, considered, prepared, scripted remark.

"Which is one of the reasons why the statements that need to be taken absolutely as gospel truth are those carefully prepared, scripted remarks."

Also his time during the Republic debate in the 90s where his main argument was that politicians shouldn't be trusted.

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Starshark
Dec 22, 2005
Doctor Rope
http://www.abc.net.au/news/2015-10-02/batty-calls-on-turnbull-to-shut-down-offshore-detention-centres/6822976

quote:

They argue that conditions at the offshore centres perpetuate violence against women, children, families and gay men.

Ms Batty wrote in the letter: "Those who care about violence against women and children need to care about what happens to people elsewhere under our care."

And we're not allowed to call her a rotten whore just because her feckless ex-husband murdered her dole-bludging son! SHE'S UNTOUCHABLE!

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