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As a total non-biologist, my guess is that if all your cells are having trouble finding the fuel to work, you won't be noticing your fingernails growing slower as your brain has suddenly stopped working.
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# ? Dec 18, 2017 10:47 |
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# ? Jun 9, 2024 04:50 |
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Grundulum posted:Thanks for the answer. That makes total sense. Another biology question, then, since it came up: why are neurons preferentially affected by an inability to make ATP? Neurons are real energy hogs.
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# ? Dec 18, 2017 11:12 |
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Remember how whenever there was a power outage, CRTs would blink out a moment before the lights? It’s like that.
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# ? Dec 18, 2017 11:46 |
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Grundulum posted:Thanks for the answer. That makes total sense. Another biology question, then, since it came up: why are neurons preferentially affected by an inability to make ATP? Your neurons have many many small pumps along their lengths which constantly push ions into and out of the cells, 'resetting' them after each and every firing. If the pumps can't get enough ATP in time your nerves can't all totally reset before they need to fire again, which may stop some signals. Having that happen to too many cells at roughly the same time can be bad. treasured8elief has a new favorite as of 12:43 on Dec 18, 2017 |
# ? Dec 18, 2017 12:36 |
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I just saw an ad on here for Sigma Aldrich. Like an ad on SA telling me to buy chemicals.
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# ? Dec 19, 2017 19:53 |
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The worst idea for the best placement.
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# ? Dec 19, 2017 20:05 |
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Tunicate posted:Neurons are real energy hogs. To elaborate: a normal adult brain weighs about 3 pounds. Around e: hell as a bio nerd I'll talk a little more. Adenosine triphosphate, ATP, is the molecule that the body (and pretty much every living thing) uses to ferry energy from one place to another. It's kind of like... it's kind of like a match: it's somewhat stable, but if you strike it/pop off one of the phosphates you get a big chunk of energy released, which can be used to set something else off. So you use a lot of it - your body burns and recycles over 50 kilos of ATP per day - too much to store for any period of time, so you just make it as you go. Anything that interrupts that process does a really, really good job of killing you. World War Mammories has a new favorite as of 20:17 on Dec 19, 2017 |
# ? Dec 19, 2017 20:12 |
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The brain is the most important organ in the body, according to the brain.
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# ? Dec 19, 2017 20:14 |
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Bhodi posted:The brain is the most important organ in the body, according to the brain. the brain lies, I wouldn't trust it.
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# ? Dec 19, 2017 20:26 |
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Bhodi posted:The brain is the most important organ in the body, according to the brain. I would totally read a Blindsight-esque book about how the brain is just an endoparasite hogging the bodies resources, and isn't actually a requirement for life to function. Obviously you can't prove that, because the brain won't let you
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# ? Dec 19, 2017 20:28 |
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You are a 3 to 5 LB oblong ball of fat and meat inside a skeleton, controlling a meat puppet
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# ? Dec 19, 2017 20:31 |
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World War Mammories posted:Anything that interrupts that process does a really, really good job of killing you. Even more specifically, excess ammonia interrupts ATP production by throwing a wrench into the citric acid cycle in your cellular mitochondria. This is a general mechanism for all sorts of really toxic stuff. Cyanide, hydrogen sulfide, nitric oxide, all do this as well (in a different way, but the end result is that the cell stops making ATP). Like ammonia, your body has enzymes to deal with these things and they're part of normal body chemistry, but if something upsets that balance lights out can happen really quickly.
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# ? Dec 19, 2017 20:42 |
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Mustached Demon posted:I just saw an ad on here for Sigma Aldrich. Like an ad on SA telling me to buy chemicals. Now we just need to have it be the only add in TCC and watch the new threads appear.
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# ? Dec 20, 2017 04:26 |
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the thing I've found that works best for cleaning electronics at work is an old bottle I pulled out of our "chemicals people have dropped off as e-waste over the years" shelf from Fisher Scientific labeled "100% 2-Propanol" and it'll strip gross degraded soft-touch coatings off of 90s cameras but hoo boy are the fumes potent
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# ? Dec 21, 2017 08:29 |
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atomicthumbs posted:the thing I've found that works best for cleaning electronics at work is an old bottle I pulled out of our "chemicals people have dropped off as e-waste over the years" shelf from Fisher Scientific labeled "100% 2-Propanol" and it'll strip gross degraded soft-touch coatings off of 90s cameras but hoo boy are the fumes potent "2-Propanol" is just another term for isopropyl alcohol. We use it as keyboard/whiteboard cleaner, don't think it really belongs in this thread.
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# ? Dec 21, 2017 10:57 |
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DigitalRaven posted:"2-Propanol" is just another term for isopropyl alcohol. We use it as keyboard/whiteboard cleaner, don't think it really belongs in this thread. it's hard to find in 100% purity and comes in a nice serious-looking brown glass bottle with a scary chemical name on it
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# ? Dec 21, 2017 12:28 |
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atomicthumbs posted:it's hard to find in 100% purity and comes in a nice serious-looking brown glass bottle with a scary chemical name on it That doesn't check out, there's no nitro-, methy[heavy metal], fluoro-, or chloro- in 2-propanol, rendering it as scary as peekaboo compared to some of the poo poo that's been mentioned in this thread.
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# ? Dec 21, 2017 12:44 |
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Yeah, keep it away from open flames and in a well-ventilated room and it's a puppy dog.
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# ? Dec 21, 2017 16:45 |
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My dad told me some hair raising anecdotes about thread favorite chlorine trifluoride being used to clean some chemical production equipment that demanded extremely low amounts of contaminant. The cell would glow red hot from the heat of the reaction, and was literally impossible to make any cleaner afterwards. So for those tough to remove stains, you know what to do.
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# ? Dec 21, 2017 16:46 |
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atomicthumbs posted:the thing I've found that works best for cleaning electronics at work is an old bottle I pulled out of our "chemicals people have dropped off as e-waste over the years" shelf from Fisher Scientific labeled "100% 2-Propanol" and it'll strip gross degraded soft-touch coatings off of 90s cameras but hoo boy are the fumes potent You can drink 100% propanol in small quantities and it'll get you incredibly hammered and give you a roaring hangover.
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# ? Dec 21, 2017 16:55 |
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If this thread teaches anything, it's that "100% purity" anything can have a very different personality than over-the-counter "mostly" grade. Hell, just a few weeks ago there was discussion about the unexpected properties of 100% pure water. And 100% pure not-water is usually "anhydrous", which is another important adjective. I wouldn't be surprised if 100% isopropanol is something you don't want in a medicine cabinet. TBF "an old bottle I pulled out of our "chemicals people have dropped off as e-waste over the years" shelf from Fisher Scientific" is the prefix most likely to be followed by a cautionary anecdote.
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# ? Dec 21, 2017 16:56 |
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Arglebargle III posted:You can drink 100% propanol in small quantities and it'll get you incredibly hammered and give you a roaring hangover. Strong avatar post combo here
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# ? Dec 21, 2017 17:03 |
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Arglebargle III posted:You can drink 100% propanol in small quantities and it'll get you incredibly hammered and give you a roaring hangover. That's 1-propanol not 2-propanol, isn't it?
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# ? Dec 21, 2017 17:19 |
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Midjack posted:So for those tough to remove stains, you know what to do. Now I'm imagining one of those Billy Mays infomercials promoting ClF3. AND IF YOU CALL NOW WE'LL THROW IN A TRAVEL SIZE BOTTLE FOR FREE!
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# ? Dec 21, 2017 17:24 |
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StandardVC10 posted:Now I'm imagining one of those Billy Mays infomercials promoting ClF3. AND IF YOU CALL NOW WE'LL THROW IN A TRAVEL SIZE BOTTLE FOR FREE! "Please allow three months for ground delivery, signature absolutely required."
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# ? Dec 21, 2017 17:56 |
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ulmont posted:That's 1-propanol not 2-propanol, isn't it? Yep. 1-propanol is thought to be somewhere between 2-4 times as potent with regards to alcohol intoxication versus ethanol. 2-propanol is toxic at 0.2 g/kg. I mean I'm sure you could probably get totally ripped off a tiny snort of pure 2-propanol but that seems like a "dear christ no" grade idea, especially what with the whole "metabolizes entirely into acetone" thing. Kazinsal has a new favorite as of 22:48 on Dec 21, 2017 |
# ? Dec 21, 2017 18:13 |
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Strom Cuzewon posted:I would totally read a Blindsight-esque book about how the brain is just an endoparasite hogging the bodies resources, and isn't actually a requirement for life to function. Here you go! Also by Peter Watts, unsurprisingly. You could also probably just read any book on botany, sponges or jellyfish.
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# ? Dec 21, 2017 20:22 |
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ulmont posted:That's 1-propanol not 2-propanol, isn't it? Probably? Acetone is bad for you. Ld-50 is 5000 mg per kilogram, so for a healthy adult that's a pretty small beaker. Maybe I should be specific if I ever repeat that propanol fact in conversation. Arglebargle III has a new favorite as of 21:25 on Dec 21, 2017 |
# ? Dec 21, 2017 21:19 |
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Strom Cuzewon posted:I would totally read a Blindsight-esque book about how the brain is just an endoparasite hogging the bodies resources, and isn't actually a requirement for life to function. It's a symbiont, actually.
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# ? Dec 21, 2017 22:55 |
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https://twitter.com/whitequark/status/947484573948153856 https://twitter.com/whitequark/status/947577022171222017 https://twitter.com/whitequark/status/947813317577527296 I love following this person on Twitter if only for the weird-rear end poo poo they get up to.
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# ? Jan 2, 2018 04:43 |
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Why is he making is very corrosive and toxic compound that is a precursor weed killer (Roundup I believe) and insecticide? It's listed as controlled under CWC, Chemical Weapons Convention.
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# ? Jan 2, 2018 05:42 |
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oohhboy posted:Why is he making is very corrosive and toxic compound that is a precursor weed killer (Roundup I believe) and insecticide? It's listed as controlled under CWC, Chemical Weapons Convention. Wanting on the no fly list?
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# ? Jan 2, 2018 05:47 |
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Mustached Demon posted:Wanting on the no fly list? You'll get on a better list than that for making that type of hell-broth!
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# ? Jan 2, 2018 05:50 |
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oohhboy posted:Why is he making is very corrosive and toxic compound that is a precursor weed killer (Roundup I believe) and insecticide? It's listed as controlled under CWC, Chemical Weapons Convention. In this thread we prefer to ask, "why not?"
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# ? Jan 2, 2018 05:52 |
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Icon Of Sin posted:You'll get on a better list than that for making that type of hell-broth! The opposite of flying list? Like the get buried list?
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# ? Jan 2, 2018 05:52 |
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oohhboy posted:Why is he making is very corrosive and toxic compound that is a precursor weed killer (Roundup I believe) and insecticide? It's listed as controlled under CWC, Chemical Weapons Convention. Hell if I know. IIRC they're also a fan of weird psychoactive chemicals but I don't quite remember. e: Also I think they work on quantum computing in Hong Kong? Basically they lead like a maximally interesting life. vOv has a new favorite as of 05:57 on Jan 2, 2018 |
# ? Jan 2, 2018 05:54 |
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What's the most gallingly disparate terminology you can think of, in terms of the innocence of the description to the deadliness of the thing or phenomenon it describes? IE, poo poo that belongs in the bottom right corner of XKCD's Scary Names graph. My money's on "physics package". I mean, yes, the core of a nuclear weapon is technically a package, that performs a certain variety of physics. It's just so horribly understated that I kinda want to grab the guy who thought it up and shake him by his lapels for a solid minute.
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# ? Jan 3, 2018 00:34 |
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Cholinesterase inhibitor. Sounds like a pill you'd take, not human-grade bug spray. You could advertise that during prime time on major networks and there'd be people asking *their* doctor about "Sarin" the next day. It's not like listing the side effects would really faze anyone. "Wow, five mentions of death! Abilify only has three! It must *really* work!" BIG HEADLINE has a new favorite as of 00:52 on Jan 3, 2018 |
# ? Jan 3, 2018 00:49 |
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Phy posted:What's the most gallingly disparate terminology you can think of, in terms of the innocence of the description to the deadliness of the thing or phenomenon it describes? A. Degloved B. Morselized
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# ? Jan 3, 2018 00:59 |
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# ? Jun 9, 2024 04:50 |
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Phanatic posted:A. Degloved Hey, Degloving isn't necessarily deadly. Horrifying yes, deadly not with medical treatment.
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# ? Jan 3, 2018 01:01 |