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Which horse film is your favorite?
This poll is closed.
Black Beauty 2 1.06%
A Talking Pony!?! 4 2.13%
Mr. Hands 2x Apple Flavor 117 62.23%
War Horse 11 5.85%
Mr. Hands 54 28.72%
Total: 188 votes
[Edit Poll (moderators only)]

 
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mod sassinator
Dec 13, 2006
I came here to Kick Ass and Chew Bubblegum,
and I'm All out of Ass

A big flaming stink posted:

So there isn't actually a potential negative event being prevented? There's no legit medical risk that over-prescribing boosters presents?

Israel specifically said from their data the risk of adverse events like mycarditis were low (only one case in their data apparently). It appears there is no risk other than cost and availability of boosters.

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Kaal
May 22, 2002

through thousands of posts in D&D over a decade, I now believe I know what I'm talking about. if I post forcefully and confidently, I can convince others that is true. no one sees through my facade.
Beetus is right, the thread is objectively better when people pay the pet tax.

Stickman
Feb 1, 2004

Taxes for the last couple of pages...

I volunteer at a wedge-tailed shearwater colony and we just had our annual chick census; 275 of these bad boys and girls in one acre:


Three weeks ago:


Five weeks ago (different chick):


E: Lol, I'm waaay too slow at typing...

Stickman fucked around with this message at 23:17 on Sep 17, 2021

mod sassinator
Dec 13, 2006
I came here to Kick Ass and Chew Bubblegum,
and I'm All out of Ass

Kaal posted:

Beetus is right, the thread is objectively better when people pay the pet tax.

Nearly 700k Americans are dead, over 2,500 are dying a day. Can we stop trivializing this disease and treat it with the respect appropriate to the #3 killer of all Americans? I don't think cute animals are appropriate in this discussion. People are loving dying.

Kaal
May 22, 2002

through thousands of posts in D&D over a decade, I now believe I know what I'm talking about. if I post forcefully and confidently, I can convince others that is true. no one sees through my facade.

mod sassinator posted:

Nearly 700k Americans are dead, over 2,500 are dying a day. Can we stop trivializing this disease and treat it with the respect appropriate to the #3 killer of all Americans? I don't think cute animals are appropriate in this discussion. People are loving dying.

When people slow down they start to behave better. If you want to actually take the pandemic seriously then treat it as more than an opportunity to vent on people.


Stickman posted:

I volunteer at a wedge-tailed shearwater colony and we just had our annual chick census; 275 of these bad boys and girls in one acre:


Three weeks ago:


Five weeks ago (different chick):


These chicks are cute, I'm sure that's a fun place to volunteer. Thanks for sharing!

Kaal fucked around with this message at 23:20 on Sep 17, 2021

Jaxyon
Mar 7, 2016
I’m just saying I would like to see a man beat a woman in a cage. Just to be sure.

mod sassinator posted:

Nearly 700k Americans are dead, over 2,500 are dying a day. Can we stop trivializing this disease and treat it with the respect appropriate to the #3 killer of all Americans? I don't think cute animals are appropriate in this discussion. People are loving dying.

Stop pretending people in this thread don't care because they disagree with you.

Probably some people posting here suck, but thread tax exists specifically because we do know this is serious and people are dying including people we know, our family, and ourselves and we need something to push off the darkness a bit.

Professor Beetus
Apr 12, 2007

They can fight us
But they'll never Beetus

Kaal posted:

When people slow down they start to behave better. If you want to actually take the pandemic seriously then treat it as more than an opportunity to vent on people.

It's this. Screaming into the void and yelling at posters here is not going to change US public policy, nor is this a US specific thread. Pet tax and appeals for common decency are things I promote here because anyone posting here is in agreement that people shouldn't die of a preventable virus and we are mostly debating the best ways to get there and commiserating together and my appeals are not about trivializing anything; they are about having the decency to respect that everyone is coming from different places wrt covid and that you should treat each other like fellow human beings.

If you can't get that then I will ask you to step away for a bit.

HelloSailorSign
Jan 27, 2011

A big flaming stink posted:

So there isn't actually a potential negative event being prevented? There's no legit medical risk that over-prescribing boosters presents?

It's because it hasn't been studied in a sufficient manner yet. We don't know what we don't know. Though if you want to volunteer I figure you can probably find a study.

I don't expect that people would go frequently enough to get boostered that they deplete their immune system's ability to fight off COVID and wind up getting COVID.

At the same time, mRNA delivery is new tech - which goes into the, "we don't know what we don't know."

We don't know if vaccine associated myocarditis is an aspect of a single vaccine dose, a time dependent vaccination related event, a numerical booster associated event, or simply an age associated event. We don't know if there's a numerical booster associated clinical signs that comes from vaccination (1st dose fine, 2nd lovely, 3rd... absolutely awful? a non event?). That's what research is for, doing enough tests with enough observation of the test subjects in order to detect rare events and tease out differences among groups.

Asking for certainty and clarity right now, in the middle of a pandemic, with things that are EUA, with things that were developed within the past 1.5 years, is completely wrong. Years go by before all the various research articles and discussion panels and pedantic arguing amongst aging specialists is done to come to a consensus, let alone understand the multi-year long process of studying the data in all the myriad ways we can think of.

UCS Hellmaker
Mar 29, 2008
Toilet Rascal
mRNA vaccines are literally star trek tech, I fully will concede I never though they would be useful or actually work, moderna had a track record of zero success or actual products. But the sheer fact is, they are insanely effective and will likely change infectious disease prevention in the future in ways we cannot really understand yet. The fact that we can make a specially targeted vaccine now that hits the spike proteins of a virus can mean possible vaccines for things we never thought was possible. I'd love to see the next gen ideas because it might mean a vaccine on hiv, ebola, rsv, colds, you name it. It's going to be a growth industry in the next 20 years and may possibly be the biggest advancement in a century for vaccines.

Shifty Pony
Dec 28, 2004

Up ta somethin'


UCS Hellmaker posted:

You really need to stop talking about mild and moderate. Needing oxygen and some lung x-ray abnormalities can mean anything and there's a massive difference in the progression of the disease. Nor does it take into account the super pneumonia that can or cannot occur which the shots actually don't do anything for. It's a coin flip that goes up if there is massive full lung infiltration from covid, which iss a serious infection.

Having low spo2 can mean you at 90% which is lol. Having spo2 that craters to goddamn 75 is what is bad. Being on a nasal cannula is not life threatening, being on high flow and bipap is going to be lasting harm.

Again, the misinformation being spread in this thread is the same poo poo endlessly by people that do not understand anything about medicine, pathophysiology of disease, and want to scream into a void because they refuse to actually listen to anyone but armchair loving morons.

Not sure what you're going off on here. I was paraphrasing the NIH's guidelines for categorizing Covid infections.

And my point was that we aren't properly considering the chronic health effects of Covid infection. You yourself are doing it by being dismissive of anything that doesn't put people's lives in immediate danger. Sure you can say "being on a nasal cannula is not life threatening" and be right when talking about a critical care ED/ICU setting, but that's completely glossing over people like my friend who lost her whole career as a result of an infection that only put her in the mid to upper 80s and was able to be managed with a cannula.

There's a whole bunch of suffering that you aren't seeing because it doesn't put people in the hospital.

Fritz the Horse
Dec 26, 2019

... of course!
Could someone link me the publications/reports from Israel about boosters? Sincere question, I've seen them referenced a ton itt but haven't seen the actual data, methodology etc. I've been busy with work but have some time this evening and weekend and would like to dig into a little more detail than news reports and secondhand mentions in forums posts.

bane mask golem
Sep 16, 2021

by Fluffdaddy

UCS Hellmaker posted:

Dude trying to make a comparison to a loving prion disease shows you have absolutely no idea what your talking about. The actual symptoms of prion disease take years if not decades to develop, and when they do it progresses rapidly, as in within a month your dead. Prions are an absolute different classification of disease that does not correlate to any other disease the people get. Half the issue in this thread is people making absolute hot take bullshit about stuff they have no knowledge or experience with. The worst of it is people reading bullshit from journalists or even nate silver who don't know anything about what they are doing.

Wow, yikes dude, there's no need to be so hostile? No, I'm not a doctor, like you clearly must be (??), and no, and I'm not saying that Covid causes prions. It was an example! Many diseases have long-term effects that aren't readily apparent in the short term, and I don't see why we should assume Covid doesn't have lasting effects. That just seems reckless and short-sighted, since we don't know what it does to peoples' brains long-term. You should read that NPR article I linked, it's pretty interesting- top experts in the field aren't sure what causes long Covid, which is why I'm saying we shouldn't assume it's harmless.

quote:

And we already know long term covid issues, it fucks your heart kidneys and lungs hard.

That's not correct. Those are the issues that arise in <2 years. Covid has only been infecting humans for less than 2 years (that we know of), we have no way of knowing how hosed up peoples' brains (and god knows what else) are going to be 5, 10, 20 years later. Especially if they catch Covid multiple times.

Are you asserting that you know, with absolute certainty, how Covid infections now will affect peoples' health 5 years from now? If you aren't asserting that, I think we should follow the precautionary principle, wear a respirator, get a booster, and try to avoid catching even a mild case of Covid.

quote:

However it's not like chicken pox, or polio which are able to insert them themselves into dna and be activated later in life. We know the general viral structure of this disease, and it's similar to Sars for Christ sakes. Covid is a coronavirus, something that people did catch well before this. It's just a coronavirus that we specifically did not have immunity for, and it's spike proteins are able to invade our cells extremely effectively.

Once again, this is a novel disease. No, I'm sure it isn't exactly the same as chicken pox or HIV or prions. I'm not claiming that Covid is the exact same as those viruses. But as far as I know (please correct me if I'm wrong?), SARS and other coronaviruses don't cause the same amount of brain damage that Covid does, which is why I think we shouldn't recklessly assume that mild Covid has no long-term ramifications.

I feel like I'm arguing with my uncle, who thinks that radiation doesn't have any health effects and nuclear fallout being bad for people is just fake news. Just because something doesn't cause obvious short-term effects, except for massive exposures (ie. radiation poisoning, or a huge viral load of Covid putting someone on a ventilator) doesn't mean smaller exposures are harmless. Quite the opposite is true for a number of other diseases, like HIV.

Google Butt
Oct 4, 2005

Xenology is an unnatural mixture of science fiction and formal logic. At its core is a flawed assumption...

that an alien race would be psychologically human.

HelloSailorSign posted:

It's because it hasn't been studied in a sufficient manner yet. We don't know what we don't know. Though if you want to volunteer I figure you can probably find a study.

I don't expect that people would go frequently enough to get boostered that they deplete their immune system's ability to fight off COVID and wind up getting COVID.

At the same time, mRNA delivery is new tech - which goes into the, "we don't know what we don't know."

We don't know if vaccine associated myocarditis is an aspect of a single vaccine dose, a time dependent vaccination related event, a numerical booster associated event, or simply an age associated event. We don't know if there's a numerical booster associated clinical signs that comes from vaccination (1st dose fine, 2nd lovely, 3rd... absolutely awful? a non event?). That's what research is for, doing enough tests with enough observation of the test subjects in order to detect rare events and tease out differences among groups.

Asking for certainty and clarity right now, in the middle of a pandemic, with things that are EUA, with things that were developed within the past 1.5 years, is completely wrong. Years go by before all the various research articles and discussion panels and pedantic arguing amongst aging specialists is done to come to a consensus, let alone understand the multi-year long process of studying the data in all the myriad ways we can think of.

what we do know is that covid will murk ur fuckin rear end lol

Professor Beetus
Apr 12, 2007

They can fight us
But they'll never Beetus

Google Butt posted:

what we do know is that covid will murk ur fuckin rear end lol

Hi there, this is a worthless post, please don't bother to engage if you don't plan on actually adding to the discussion.

e: or at least be funnier or post an animal pic or something

e2: thank you.

Professor Beetus fucked around with this message at 00:47 on Sep 18, 2021

Google Butt
Oct 4, 2005

Xenology is an unnatural mixture of science fiction and formal logic. At its core is a flawed assumption...

that an alien race would be psychologically human.

Professor Beetus posted:

Hi there, this is a worthless post, please don't bother to engage if you don't plan on actually adding to the discussion.

e: or at least be funnier or post an animal pic or something

Fritz the Horse
Dec 26, 2019

... of course!
Nevermind I'm home and tracked down the Israeli booster study, here is the full publication I believe:

https://www.nejm.org/doi/full/10.1056/NEJMoa2114255

I'll give it a read this evening and might post some thoughts. I don't know that I particularly trust Bloomberg or Business Insider to do very thorough science reporting. Not disputing anything posted here regarding the study, I just prefer to have the actual document and discuss it with a few other people who've read it.

edit: :siren: at a glance, one big thing here is this study is looking at boosters for people aged 60 and older which means you really can't extrapolate these results to the US general population.

Unless there's another Israeli booster study that involves people under age 60 that I didn't find?

edit2: there's also this slide deck from the Israeli Ministry of Health that was released by the FDA today: https://www.fda.gov/media/152205/download

That might have information in addition to the above. I won't have a chance to look through it for a bit.

Fritz the Horse fucked around with this message at 01:04 on Sep 18, 2021

empty whippet box
Jun 9, 2004

by Fluffdaddy

this dog looks like it's about to vote to shoot me out of an airlock

HonorableTB
Dec 22, 2006
News from my hometown!



Ah.

Hy_C
Apr 1, 2010



Epic High Five posted:

This was just an advisory committee sending a decision to the FDA itself wasn't it? I expect an actual report of their reasoning will come out once they formalize it, at least I'd HOPE that one will.

That's correct, they only provide recommendations to the FDA. The FDA typically has go with the advisory committee's recommendations (googling around gave me ~75% figure but nothing official). The FDA does not in any shape or form have to follow their advice at all and most recently completely ignored the advisory committee when approving the Alzheimer's drug, Aduhelm (aducanumab).

The chair of the advisory committee Peter Marks is the CBER Director at the FDA (CBER approves and provides regulatory guidance over Vaccine approvals). During the call reminded the advisory committee the FDA does not have to follow their guidance so I would not be surprised if the booster approval is much broader than what was discussed and voted upon at the meeting. To top it off both the Acting FDA Commissioner and the White House have been in support for boosters too.

Discendo Vox
Mar 21, 2013

We don't need to have that dialogue because it's obvious, trivial, and has already been had a thousand times.

Hy_C posted:

That's correct, they only provide recommendations to the FDA. The FDA typically has go with the advisory committee's recommendations (googling around gave me ~75% figure but nothing official). The FDA does not in any shape or form have to follow their advice at all and most recently completely ignored the advisory committee when approving the Alzheimer's drug, Aduhelm (aducanumab).

The chair of the advisory committee Peter Marks is the CBER Director at the FDA (CBER approves and provides regulatory guidance over Vaccine approvals). During the call reminded the advisory committee the FDA does not have to follow their guidance so I would not be surprised if the booster approval is much broader than what was discussed and voted upon at the meeting. To top it off both the Acting FDA Commissioner and the White House have been in support for boosters too.

Conversely, FDA going against the Aduhelm recommendation was perhaps the biggest scandal in the past 30 years at the agency.

Fritz the Horse
Dec 26, 2019

... of course!
I did some homework. Here's my summary of the Israeli booster data.

Data are from:
https://www.nejm.org/doi/full/10.1056/NEJMoa2114255 Full peer-reviewed publication in booster shots for people ages >60, published 15 Sept
https://www.fda.gov/media/152205/download Israeli Ministry of Health powerpoint slides released by FDA 17 Sept


Timeline:
March 2021 - Israel reaches high levels of full vaccination, ~3 months before other countries
March 7th - Israel fully reopens
June - Delta takes over as dominant variant
July through early August - 10x increase in severe cases 60% of which are fully vaccinated, data show immunity waning
July 30th - Booster shots start for >60. Younger age groups eligible in following weeks.

The data here support:
-Vaccine effectiveness vs. infection wanes for all ages

-Vaccine effectiveness vs. severe disease wanes for >60

-Booster shot is effective at decreasing infection for all age groups
-Booster shot is effective at decreasing severe disease for >60
-Low rate of adverse events at this time


We don't know:
-If effectiveness vs. severe disease wanes for people under 60

-If a booster shot improves effectiveness vs. severe disease for people under 60
-How long the booster helps (simply hasn't been enough time)

My takeaways:
-Boosters definitely should be rolled out for elderly and immunocompromised because their immunity to severe disease wanes and a booster is effective. It is predicted that Israel's hospital system would have been overwhelmed without boosters or if boosters for 60+ were rolled out weeks later. This emphasizes urgency of getting boosters out to high-risk populations in the US, we are a few months behind Israel.

-Vaccine protection vs. infection wanes for everyone and boosters improve that
-There is not evidence to support waning immunity vs. severe disease for those under 60 or that a booster helps against severe disease in those groups
-We won't have good data on how long the boosters are effective or on how well they work vs. severe disease in younger people just because it will take time to have enough cases of severe illness to be statistically meaningful


edit: those are some big error bars on a lot of those plots.
edit2: added info about Israeli hospital system predicted to be overwhelmed if no booster or boosters administered several weeks later.
Yes, I know that these data do not break things down by immune status or underlying conditions but I'm lumping immunocompromised people in with the elderly because it seems entirely reasonable to do so and boosters are going to them in the US already :shrug:

also also, this is all Pfizer vaccine. Moderna, J&J, and mixed regimens may be different especially I would think with regard to timeframes.

Fritz the Horse fucked around with this message at 02:46 on Sep 18, 2021

Fritz the Horse
Dec 26, 2019

... of course!
Oh also, I'm not sure what Israel's lockdown and reopening were like. The study says they fully reopened on March 7th. Does that mean no mask mandates or anything? Did Israel remain fully open since?

Someone else can look into those if it's of interest, I need to graze for a bit.

empty whippet box
Jun 9, 2004

by Fluffdaddy

HonorableTB posted:

News from my hometown!




lol, in 3 months they'll have space for 15 more bodies. That, uh, doesn't seem like it's going to be enough to me.

Charles 2 of Spain
Nov 7, 2017

Fritz the Horse posted:

I did some homework. Here's my summary of the Israeli booster data.

Data are from:
https://www.nejm.org/doi/full/10.1056/NEJMoa2114255 Full peer-reviewed publication in booster shots for people ages >60, published 15 Sept
https://www.fda.gov/media/152205/download Israeli Ministry of Health powerpoint slides released by FDA 17 Sept


Timeline:
March 2021 - Israel reaches high levels of full vaccination, ~3 months before other countries
March 7th - Israel fully reopens
June - Delta takes over as dominant variant
July through early August - 10x increase in severe cases 60% of which are fully vaccinated, data show immunity waning
July 30th - Booster shots start for >60. Younger age groups eligible in following weeks.

The data here support:
-Vaccine effectiveness vs. infection wanes for all ages

-Vaccine effectiveness vs. severe disease wanes for >60

-Booster shot is effective at decreasing infection for all age groups
-Booster shot is effective at decreasing severe disease for >60
-Low rate of adverse events at this time


We don't know:
-If effectiveness vs. severe disease wanes for people under 60

-If a booster shot improves effectiveness vs. severe disease for people under 60
-How long the booster helps (simply hasn't been enough time)

My takeaways:
-Boosters definitely should be rolled out for elderly and immunocompromised because their immunity to severe disease wanes and a booster is effective. It is predicted that Israel's hospital system would have been overwhelmed without boosters or if boosters for 60+ were rolled out weeks later. This emphasizes urgency of getting boosters out to high-risk populations in the US, we are a few months behind Israel.

-Vaccine protection vs. infection wanes for everyone and boosters improve that
-There is not evidence to support waning immunity vs. severe disease for those under 60 or that a booster helps against severe disease in those groups
-We won't have good data on how long the boosters are effective or on how well they work vs. severe disease in younger people just because it will take time to have enough cases of severe illness to be statistically meaningful


edit: those are some big error bars on a lot of those plots.
edit2: added info about Israeli hospital system predicted to be overwhelmed if no booster or boosters administered several weeks later.
Yes, I know that these data do not break things down by immune status or underlying conditions but I'm lumping immunocompromised people in with the elderly because it seems entirely reasonable to do so and boosters are going to them in the US already :shrug:

also also, this is all Pfizer vaccine. Moderna, J&J, and mixed regimens may be different especially I would think with regard to timeframes.
Did they publish this table which was in the original preprint (maybe it's integrated into the figure somewhere)?


Also should be noted that while Israel had high levels of full vaccination in March, it's been surpassed by a lot of other countries (not the US though, whose rate is abysmal), but this might be to do with the eligible population being more.

Fritz the Horse
Dec 26, 2019

... of course!

Charles 2 of Spain posted:

Did they publish this table which was in the original preprint (maybe it's integrated into the figure somewhere)?


Also should be noted that while Israel had high levels of full vaccination in March, it's been surpassed by a lot of other countries (not the US though, whose rate is abysmal), but this might be to do with the eligible population being more.

The actual published document does not appear to contain any data for groups under age 60, including the supplement. That table is not in there.

It does appear integrated into the slide stack https://www.fda.gov/media/152205/download, specifically in slides #13, 14, and 15 all of which I posted above. I'll repost them here:





edit: it's formatted/standardized differently but appears to be the same stuff as in your table.

Fritz the Horse fucked around with this message at 03:35 on Sep 18, 2021

Epic High Five
Jun 5, 2004



Thank you Fritz for the detailed analysis, I'll respond to it tomorrow when I've got more time to formulate something your posts deserve but I wanted to let you know that I appreciate you poring over the data for our benefit

Hy_C posted:

That's correct, they only provide recommendations to the FDA. The FDA typically has go with the advisory committee's recommendations (googling around gave me ~75% figure but nothing official). The FDA does not in any shape or form have to follow their advice at all and most recently completely ignored the advisory committee when approving the Alzheimer's drug, Aduhelm (aducanumab).

The chair of the advisory committee Peter Marks is the CBER Director at the FDA (CBER approves and provides regulatory guidance over Vaccine approvals). During the call reminded the advisory committee the FDA does not have to follow their guidance so I would not be surprised if the booster approval is much broader than what was discussed and voted upon at the meeting. To top it off both the Acting FDA Commissioner and the White House have been in support for boosters too.

This is good to hear at least, it seems a bit much to pray for a palace coup but I hope they take their recommendation and largely discard it in favor of something more in line with out current strategy of "vaccinations will save us all"

HonorableTB posted:

News from my hometown!



Ah.



News from my own hometown:

Herstory Begins Now
Aug 5, 2003
SOME REALLY TEDIOUS DUMB SHIT THAT SUCKS ASS TO READ ->>

empty whippet box posted:

lol, in 3 months they'll have space for 15 more bodies. That, uh, doesn't seem like it's going to be enough to me.

For a county with 60,000 people you really don't need a ton of morgue capacity.

Discendo Vox
Mar 21, 2013

We don't need to have that dialogue because it's obvious, trivial, and has already been had a thousand times.
Let me get this straight: they removed their nonsignificant results and only reported the ones that showed effect. That's downright magical.

...do they control for familywise error?

edit: they do not. They do not even report on the sample structure in their protocol document.

Discendo Vox fucked around with this message at 04:06 on Sep 18, 2021

Charles 2 of Spain
Nov 7, 2017

Are you saying there's no adjustment for multiple comparisons or something else?

Phigs
Jan 23, 2019

As a non-American I've never had much faith in American institutions so I don't even know why a person would trust the FDA implicitly 10 years ago, but how a person can sit there and say "well the FDA said..." today I just don't understand. Refusing to recommend boosters smacks of technocratic bullshit to me. I legit don't see why you don't at least allow doctors to prescribe them. The two biggest data points we have on boosters is that the shots have very low rates of significant adverse effects and 60+ patients see a reduction in infection rate and severity. Which was enough to recommend it for 60+ and high risk groups... but not enough to cover our bases on the other groups? I can see not wanting to extrapolate in general, but a loving pandemic that's killing thousands every day sure seems like a time where you don't "well actually" the approval process. I could see not wanting to roll out a booster program without more info, but to not even allow it for prescription is some real bullshit.

Think about all the poo poo that's optional during this pandemic that really loving should be mandatory but no we have to give people the choice. Don't wanna wear a mask in spite of how effective they are vs the cost? Sure, depending on where you go. Don't wanna get vaccinated ion spite of overwhelming evidence that they save lives? Sure, depending where you work. Wanna get boosters in spite of the lack of data? Nah, gently caress off if you're not 60+, wouldn't want you making a choice that could be sub-optimal.

This entire train wreck of a response to the pandemic has been regulators dragging their feet and always, loving always erring on the side of less intervention. No need to wear masks anymore cause of the vaccine! Instead of maybe we wait until we have data backing up the idea that we won't wear masks? Nope, full steam ahead. Open up the schools. Work from home is over. Pack the restaurants. Pack the stadiums. Open up travel. Oh but don't recommend n95s and don't allow boosters. That would be reckless! We don't have the data! People could be risking their health!

loving incredible.

HelloSailorSign
Jan 27, 2011

Phigs posted:

but a loving pandemic that's killing thousands every day

*Which are overwhelmingly the unvaccinated.

Phigs posted:

Nah, gently caress off if you're not 60+, wouldn't want you making a choice that could be sub-optimal.

It's about ensuring we maintain appropriate regulatory facilities and protocols while groups - largely the Pharma companies which would benefit from everyone taking their drugs/vaccines regularly and other benefits to emergency testing, emergency studies, etc., which the definition of "emergency" could be... pushed - push to try and remove said regulatory agency while using the fig leaf of, "but things went slow!"

We're acting as much for the pandemic of today for the pandemic of tomorrow and the drug testing and research of tomorrow.

Meanwhile, nobody's going gently caress off, we're saying, "the data is not there yet." Public health is nuance, that people don't understand it isn't a problem of public health, it's a problem of people who lack the basic understanding thinking they've got the One Weird Trick to fix the pandemic.


Phigs posted:

As a non-American I've never had much faith in American institutions [...]Think about all the poo poo that's optional during this pandemic that really loving should be mandatory but no we have to give people the choice. Don't wanna wear a mask in spite of how effective they are vs the cost? Sure, depending on where you go. Don't wanna get vaccinated ion spite of overwhelming evidence that they save lives? Sure, depending where you work.

As you're a non-American, perhaps you're not familiar with the law enforcement and local government agencies that would probably use increased powers to infringe on people's rights to poo poo even further down minorities necks, but any push that seeks to apply greater pressure to people via law enforcement apparatuses is.... fraught with peril.


Phigs posted:

This entire train wreck of a response to the pandemic has been regulators dragging their feet and always, loving always erring on the side of less intervention.

- No mask wearing was a bad judgment call based on a feet dragging by people who wanted to define large droplet vs. airborne while also probably thinking they could save PPE that way.
- Open up the schools is a heavily nuanced opinion that involves far more than "COVID, yes/no" and, as you're a non-American, you likely don't understand the issues that American parents face wrt childcare in the US
- While I've nervously bitten my nails over things like BLM protests, sports games, Provincetown Gay Orgy Festival, and Lollapalloza (sp), largely we've found that these things have gone over well (i.e. did not have large outbreaks associated with them) as long as people don't spend time indoors and were decently vaccinated. Things like Sturgis where people probably spent time in bars coughing on each other because lmao COVID while also being largely unvaccinated did result in increased cases.

There's a lot to be frustrated about for sure, but you're a bit off base on a majority of things here.

How are u
May 19, 2005

by Azathoth
It doesn't seem technocratic to me, could you maybe expand on why you think that? The Biden admin has been pushing the idea of boosters pretty hard, they clearly, clearly want to roll them out. The FDA coming out against the need for immediate boosters for the public at large seems to me to be pretty clearly scientists pushing back against popular public perception that boosters are necessary, based on science and data.

empty whippet box
Jun 9, 2004

by Fluffdaddy

HelloSailorSign posted:

*Which are overwhelmingly the unvaccinated.



Could you explain your intent in saying this here?

WAR CRIME GIGOLO
Oct 3, 2012

The Hague
tryna get me
for these glutes

Ive taken a hydrochloroquine, ivmectrin mixture rectally

i no covid

Platystemon
Feb 13, 2012

BREADS

HelloSailorSign posted:

- While I've nervously bitten my nails over things like BLM protests, sports games, Provincetown Gay Orgy Festival, and Lollapalloza (sp), largely we've found that these things have gone over well (i.e. did not have large outbreaks associated with them) as long as people don't spend time indoors and were decently vaccinated. Things like Sturgis where people probably spent time in bars coughing on each other because lmao COVID while also being largely unvaccinated did result in increased cases.

Sturgis led to fewer documented cases than Lollapalooza.

HelloSailorSign
Jan 27, 2011

empty whippet box posted:

Could you explain your intent in saying this here?

Because the complaint was within the general paragraph complaining about the booster decision process, which is about something to be done in the already vaccinated, who are a vastly minor slice of the "deaths per day" pie.

Herstory Begins Now
Aug 5, 2003
SOME REALLY TEDIOUS DUMB SHIT THAT SUCKS ASS TO READ ->>

Phigs posted:

As a non-American I've never had much faith in American institutions so I don't even know why a person would trust the FDA implicitly 10 years ago, but how a person can sit there and say "well the FDA said..." today I just don't understand. Refusing to recommend boosters smacks of technocratic bullshit to me. I legit don't see why you don't at least allow doctors to prescribe them. The two biggest data points we have on boosters is that the shots have very low rates of significant adverse effects and 60+ patients see a reduction in infection rate and severity. Which was enough to recommend it for 60+ and high risk groups... but not enough to cover our bases on the other groups? I can see not wanting to extrapolate in general, but a loving pandemic that's killing thousands every day sure seems like a time where you don't "well actually" the approval process. I could see not wanting to roll out a booster program without more info, but to not even allow it for prescription is some real bullshit.

Think about all the poo poo that's optional during this pandemic that really loving should be mandatory but no we have to give people the choice. Don't wanna wear a mask in spite of how effective they are vs the cost? Sure, depending on where you go. Don't wanna get vaccinated ion spite of overwhelming evidence that they save lives? Sure, depending where you work. Wanna get boosters in spite of the lack of data? Nah, gently caress off if you're not 60+, wouldn't want you making a choice that could be sub-optimal.

This entire train wreck of a response to the pandemic has been regulators dragging their feet and always, loving always erring on the side of less intervention. No need to wear masks anymore cause of the vaccine! Instead of maybe we wait until we have data backing up the idea that we won't wear masks? Nope, full steam ahead. Open up the schools. Work from home is over. Pack the restaurants. Pack the stadiums. Open up travel. Oh but don't recommend n95s and don't allow boosters. That would be reckless! We don't have the data! People could be risking their health!

loving incredible.

Because the fda is generally incredibly competent and one of the few actually reliably competent parts of the us government.

Anyways as to your main point: no one is really being prevented from getting booster shots. HCWs and other at risk people are getting them. For random people with no co-morbidities, every booster they get is a first shot someone else can't get. Last I heard, the serious discussion around boosters on a policy level is whether to prioritize boosters or getting more first shots in people (and particularly by exporting more doses).

My personal feeling is that exporting more doses is vastly more important and more of a moral plus than making already safe people marginally safer. Especially since the amount of vaccine waste domestically is pretty high compared to the percent of shots you can get into arms in countries with low vaccination rates.

Phigs
Jan 23, 2019

How are u posted:

It doesn't seem technocratic to me, could you maybe expand on why you think that?

What I mean is this:

HelloSailorSign posted:

It's about ensuring we maintain appropriate regulatory facilities and protocols

Basically it smacks to me of a decision that values the above more than it values the health and safety of the population.


EDIT:

Herstory Begins Now posted:

My personal feeling is that exporting more doses is vastly more important and more of a moral plus than making already safe people marginally safer. Especially since the amount of vaccine waste domestically is pretty high compared to the percent of shots you can get into arms in countries with low vaccination rates.

I'm going to consider this a distraction tactic until we see actual, real plans to export doses AND evidence that boosters will impact those plans.

Phigs fucked around with this message at 05:45 on Sep 18, 2021

Discendo Vox
Mar 21, 2013

We don't need to have that dialogue because it's obvious, trivial, and has already been had a thousand times.
Phigs, you straight up do not know anything about the "technocratic bullshit" you are attacking. Just for one example, the FDA lost the ability to directly regulate prescription decisions due to a suit from WLF a long time ago (iirc the first case in the most recent run was 1997), and their ability to regulate related marketing activity has been under continuous attack ever since. It's the basis of the currently widespread practice of offlabeling and probably has an 8-digit deathtoll.

Discendo Vox fucked around with this message at 05:50 on Sep 18, 2021

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mod sassinator
Dec 13, 2006
I came here to Kick Ass and Chew Bubblegum,
and I'm All out of Ass
https://twitter.com/9Joe9/status/1439068538539499520

There is a non-zero chance the President of the United States is sick and/or spreading COVID-19.

He was coughing so much on Thursday reporters point blank asked Psaki, is the President OK? https://www.realclearpolitics.com/video/2021/09/16/nbcs_kelly_odonnell_to_psaki_whats_up_with_president_bidens_coughing.html

I guess we see what happens if things get worse or they get a positive test on him. It's almost a year to the day when Trump got sick and was hospitalized in early October last year.

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