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Which horse film is your favorite? This poll is closed. |
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| Black Beauty |
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2 | 1.06% |
| A Talking Pony!?! |
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4 | 2.13% |
| Mr. Hands 2x Apple Flavor |
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117 | 62.23% |
| War Horse |
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11 | 5.85% |
| Mr. Hands |
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54 | 28.72% |
| Total: | 188 votes | ||
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UCS Hellmaker posted:pfizer and moderna use different things with the Mrna, and utilize different types of carrier lipids, its not the same thing Technically correct but they both encode for the same spike but moderna makes "more" spikes. They are different instructions to build identical proteins.
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Oct 26, 2021 22:00
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Owlofcreamcheese posted:I mean, you should get boosters, that is the recommendation, you should not make up weird fake internet plans to change up the dosing and scheduling to something some internet IT manager told you was the real one. People got boosters based on real-world data from Pfizer and Israel, as has been pointed out since the start of this conversation—now multiple times. But please, keep posting your way through this.
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Oct 26, 2021 22:06
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enki42 posted:I don't think anyone in this thread is recommending anything other than a booster at 6 months. I am recommending boosters at two months for Johnson & Johnson recipients. Platystemon fucked around with this message at 22:17 on Oct 26, 2021 |
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Oct 26, 2021 22:07
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Not that I think any of the following calls for mod action or whatever or that I disagree with the advice given, but lol people right here in this thread are recommending boosters based on twitter screen shots, gut feel, and journalists' interpretation of pre-prints, and no one seems to careFritz the Horse posted:Not too far back someone linked a twitter post "ranking" the mix-n-match combinations based on data showing antibody levels. I can dig it up later tonight when I have a few minutes or if someone finds it, repost I guess? Professor Beetus posted:I still think the best answer is "whatever you can get first." You're going to be well-protected from Covid either way. Bel Shazar posted:My impression was the min-max was "ok good you got whatever, now get a moderna shot"
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Oct 26, 2021 22:57
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Hey, look, some actual news! FDA panel greenlights vaccines for kids, paving the way for authorization https://abcnews.go.com/Health/fda-panel-greenlights-vaccines-kids-kicking-off-authorization/story?id=80778124 quote:Vaccines for 28 million American children are on the way to authorization after an advisory panel at the Food and Drug Administration voted in support of the Pfizer vaccine for kids 5-11 on Tuesday afternoon.
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Oct 26, 2021 22:59
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fosborb posted:Not that I think any of the following calls for mod action or whatever or that I disagree with the advice given, but lol people right here in this thread are recommending boosters based on twitter screen shots, gut feel, and journalists' interpretation of pre-prints, and no one seems to care Not sure what you're implying by including my post in there, but the FDA approved boosters for recipients of all 3 vaccines given in the US six days ago. If you're 6 months past your initial vaccine, you're probably eligible depending on other risk factors. I don't think people should take medical advice from randoms on the internet but boosters are a thing now regardless of the stupid slapfight over the Israeli study and how some people on SA reacted to it. Fighting Trousers posted:Hey, look, some actual news! Thanks for sharing, this is great news and I hope it proceeds as quickly as the article speculates.
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Oct 26, 2021 23:20
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Professor Beetus posted:Not sure what you're implying by including my post in there, but the FDA approved boosters for recipients of all 3 vaccines given in the US six days ago. If you're 6 months past your initial vaccine, you're probably eligible depending on other risk factors. I don't think people should take medical advice from randoms on the internet but boosters are a thing now regardless of the stupid slapfight over the Israeli study and how some people on SA reacted to it Someone asked a sincere question about what booster they should get and you gave your sincere advice that they should get whatever is first available. If you provided a source that says we should do that instead of following the original vaccine schedule, or do some combo hack, I missed it and I'm sorry, though I would like to read it! the booster slap fight is silly because we are all doing the same thing right now: gathering the best information possible of an incredibly limited, low reviewed dataset, when official advice in the US has for the last 6 days been little more than follow your brand preference. This is the limit of the advice I can find on the CDC pages right now quote:Some people may have a preference for the vaccine type that they originally received, and others may prefer to get a different booster. CDC’s recommendations now allow for this type of mix and match dosing for booster shots. That is insane, but in the absence of any guidance, its creating a relatively low bar for recommending one vaccine over the other.
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Oct 26, 2021 23:43
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Platystemon posted:Where were you when Canada and the UK were giving the second shot at intervals much greater than had been tested in the clinical trials? I don't know about Canada but I'm pretty sure the British government did this purely to try to get the first dose numbers up as high as possible as fast as possible so they could reopen sooner, and the fact that a longer dose interval turned out to be more efficacious was sheer luck.
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Oct 26, 2021 23:43
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fosborb posted:Someone asked a sincere question about what booster they should get and you gave your sincere advice that they should get whatever is first available. If you provided a source that says we should do that instead of following the original vaccine schedule, or do some combo hack, I missed it and I'm sorry, though I would like to read it! I mean I think you hit the nail on the head? I said that because that was the original advice given about vaccines in the first place; get what you can because it's better than getting covid. My first response to that poster was Professor Beetus posted:I'm not sure anyone qualified to answer that is still willing to post here but that sounds like spurious reasoning at best. Bigger/more doses does not necessarily translate to better/more protected, just like getting 4 boosters by using fake names at various pharmacies isn't going to make you super protected. If you have access to a doctor, I'd ask what they recommend, but the only answer well-suited to this thread is "get whatever booster you can, if you're eligible." I wasn't fully vaxxed until end of May, so I'm planning on going in for one next month. Which as far as I can tell based on current FDA and CDC guidance is accurate. I agree that that is insane and we are not in disagreement.
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Oct 26, 2021 23:51
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fosborb posted:Someone asked a sincere question about what booster they should get and you gave your sincere advice that they should get whatever is first available. If you provided a source that says we should do that instead of following the original vaccine schedule, or do some combo hack, I missed it and I'm sorry, though I would like to read it! CDC’s guidance on booster selection: quote:Individual benefit-risk considerations for selecting which booster dose to receive https://www.cdc.gov/vaccines/covid-19/clinical-considerations/covid-19-vaccines-us.html#considerations-covid19-vax-booster Note also the admission that the Janssen shot is worse in immunocompromised persons. CDC’s bold: quote:Moderately and severely immunocompromised people aged ≥18 years who completed an mRNA COVID-19 vaccine primary series and received an additional mRNA vaccine dose may receive a single COVID-19 booster dose […]
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Oct 26, 2021 23:55
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freebooter posted:I don't know about Canada but I'm pretty sure the British government did this purely to try to get the first dose numbers up as high as possible as fast as possible so they could reopen sooner, and the fact that a longer dose interval turned out to be more efficacious was sheer luck. Exactly the same thing in Canada, I promise you. It still pisses me off that I had to struggle to get the first available vaccine, and I did so without a second thought, and now we have vaccination rates stagnating because of the 30% of complete loving morons. Is there a big urban/rural divide in Australia? Here we have serious problems with cities being really pro-vaccination (rates of 80-90% of eligible people with a vaccine) and then rural areas dogging it around 50%, because they spend too much time violating livestock and reading Facebook.
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Oct 27, 2021 00:08
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freebooter posted:I don't know about Canada but I'm pretty sure the British government did this purely to try to get the first dose numbers up as high as possible as fast as possible so they could reopen sooner, and the fact that a longer dose interval turned out to be more efficacious was sheer luck.
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Oct 27, 2021 00:15
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Yeah it was entirely due to lack of supply and delayed deliveries that Canada did the shot schedule that we did, not because there was really any evidence it was a good idea (which makes it a bit funny that it might look now that the extended schedule may provide more protection). Like I do think sometimes Americans don't realize exactly how lucky they were with the vaccine supply, since y'all were pretty much the only ones that didn't have any real supply issues. Makes it extra frustrating that with all that supply you still had so many more idiots refusing the shots since most countries would have killed for that kind of easy supply. That being said it wasn't like the longer shot interval was set in stone or anything, it was just "At most 16 weeks, might be sooner depending on the situation". Sure, you got an appointment for four months from your first shot back in the spring but once they opened up shots more when supplies eased, If you managed to find an earlier appointment (which most people did) you got whatever that interval was. I'd say most people were around 2-3 months, a small minority were the full four, and some got it as soon as after a month. I'm pretty sure now if you get a shot they tell you to come back in a month.
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Oct 27, 2021 00:39
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PT6A posted:Is there a big urban/rural divide in Australia? Here we have serious problems with cities being really pro-vaccination (rates of 80-90% of eligible people with a vaccine) and then rural areas dogging it around 50%, because they spend too much time violating livestock and reading Facebook. There is, but there is also a huge divide between the states (or even regions) that have had outbreaks and those that haven't. Some areas of regional NSW are some of the most vaxxed areas of the country. EDIT: eg Central West and Far West NSW have double vaxx rates >85% of the eligible population, which is around the state average and higher than anywhere outside of NSW/ACT (including the other capital cities). This is due to the outbreaks around Dubbo etc during mid August, which lead to a big vaccination push in the area.  Map from here The most notably anti-vaxx area is in northern NSW (Richmond-Tweed in the SA4 list) and it's a hippy area that gentrified massively and is now the kind of place you'd find a lot of instagram wellness influencers and celebrities on holiday. Doctor Spaceman fucked around with this message at 02:26 on Oct 27, 2021 |
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Oct 27, 2021 01:35
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freebooter posted:I don't know about Canada but I'm pretty sure the British government did this purely to try to get the first dose numbers up as high as possible as fast as possible so they could reopen sooner, and the fact that a longer dose interval turned out to be more efficacious was sheer luck. Canada absolutely did this to get their first shot percentage higher. It wasn't explicitly tied to any reopening metrics (vaccine percentage based re-opening metrics came much later when the schedules weren't quite so stretched out), but I'm sure it was a factor to some degree. Supply was also a huge factor in Canada, and in early 2021, there was a lot of attention paid to the fact that Canada was lagging in supply compared to the US and the UK. We have no domestic manufacturing capability, so had to rely on shipments from other countries, and were especially hosed by the US's hard stance against vaccine exports in early 2021. Also the window where we had extremely long spacing was relatively short. The very early cohort (primarily healthcare workers and people in LTC facilities) got doses at the standard schedule. Maybe a couple of 80+ people snuck in there as well (my grandma is 90, didn't delay in getting vaccinated and had her second dose delayed, so I think this is a fairly small group). After that, by the time we got down to vaccinating 40 and below, the supply issues were mostly resolved and second doses would have been shorter than 16 weeks, although probably not quite the 3-4 weeks recommended unless you waited for your first shot. Also this is Ontario-specific, every province and even in some cases every PHU within a province is going to be different (I went to a neighbouring PHU for my first dose since they were vaccinating highest-risk health conditions way ahead of everyone else) enki42 fucked around with this message at 03:55 on Oct 27, 2021 |
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Oct 27, 2021 02:17
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Didn't Canada end up buying enough vaccines for five times their population or something?
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Oct 27, 2021 02:51
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Charles 2 of Spain posted:Didn't Canada end up buying enough vaccines for five times their population or something? We ordered a fuckload but we ordered wide, at least with the initial orders, in case some or most failed. Pfizer, AZ, Moderna, J&J (which still hasn't delivered a single shot lol), Novovax, GSK, Medicago, etc... The last three were huge orders on the scale of our Pfizer order and they haven't even been approved yet, let alone started shipping. As far as I know we've started donating a bunch of our surplus minus enough to keep a consistent stockpile for kids, holdouts, and old people boosters (e.g. B.C recently returned 300k Moderna doses it anticipated it wouldn't need to send to COVAX, IIRC any AZ we receive now gets sent out since it's been phased out here, etc..). Still could be doing more but it's a start. Mr Luxury Yacht fucked around with this message at 03:16 on Oct 27, 2021 |
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Oct 27, 2021 03:10
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freebooter posted:I don't know about Canada but I'm pretty sure the British government did this purely to try to get the first dose numbers up as high as possible as fast as possible so they could reopen sooner, and the fact that a longer dose interval turned out to be more efficacious was sheer luck. The sheer luck thing I have to dispute. That had the backing of established vaccine science and was spoken about as a good idea even when it was made a policy decision by the UK. Dr Norman Swann on Coronacast had researchers on to talk about how the immune system worked, why other vaccines use a longer interval and why Covid-19 vaccines were going to be better with a longer initial interval - the thing was that there was an accepted position of getting as many people full vacced as soon as possible if supplies were availible. IF you could wait two to three months for the second shot, there was evidence very early that would be better and established vaccine science had many examples where this held true, there was no reason to think Covid-19 vaccines would be any different.
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Oct 27, 2021 09:03
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Why did the child vaccine announcement make like, zero impact?
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Oct 27, 2021 15:52
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Owlofcreamcheese posted:Why did the child vaccine announcement make like, zero impact? It's not fully approved yet, just went through the panel review. It will probably make more news when it is fully approved in the next week or so.
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Oct 27, 2021 15:54
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Heck Yes! Loam! posted:It's not fully approved yet, just went through the panel review. It will probably make more news when it is fully approved in the next week or so. Yeah, it's unequivocally good news, but it was a very preliminary announcement. I'm hoping we get more info by the end of the week or early next week.
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Oct 27, 2021 16:06
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Owlofcreamcheese posted:Why did the child vaccine announcement make like, zero impact? Because only a minority of parents will vaccinate their 5-11 year old(s). I’d be shocked if the 5-11 demographic cracks 40%.
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Oct 27, 2021 17:26
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I dunno, up here there's not a significant drop-off for 12-17 year olds (they're even a bit higher than 18-29 year olds). 12-17 can definitely make their own decisions about vaccination, but I'd imagine a lot of them are still heavily influenced by their parents. For context, 12-17 is 83.51% first dose, 77.68% second dose, and 18-29 is 83.11% first dose, 77.10% second. For sure there will be a lot of misinformation circulating around about how we don't know the long term effects, and how could you dare put your children at risk, but IMO both the people spreading this and the audience is still going to be the same population resisting vaccines in the first place. enki42 fucked around with this message at 17:47 on Oct 27, 2021 |
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Oct 27, 2021 17:42
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It will vary by region, by state, and by locality, as it has always been. Broadly speaking though, I would be very surprised if 5-11 isn’t the least vaccinated demographic, especially now that we’ve done such a wonderful job infecting so many of them.
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Oct 27, 2021 17:46
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5-11 year olds aren't making their own medical decisions so I'd expect it to closely match the vaccination rates of their parents
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Oct 27, 2021 17:52
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enki42 posted:I dunno, up here there's not a significant drop-off for 12-17 year olds (they're even a bit higher in first dose than 18-29 year olds). 12-17 can definitely make their own decisions about vaccination, but I'd imagine a lot of them are still heavily influenced by their parents. Yeah, this. I don't think a majority of parents are anti-vaxxers who will refuse to vaccinate their kids, because anti-vax parents who refuse to vaccinate their kids were and are still a minority. We'll find out in a few months, and hopefully the that trend will continue. Gio posted:Because only a minority of parents will vaccinate their 5-11 year old(s). I’d be shocked if the 5-11 demographic cracks 40%. What makes you think anti-vax parents are the majority? I have no doubt that they will be a significant thorn in the side of getting vaccination numbers up but to say they are a majority of parents doesn't seem like something grounded in reality. Kids get mandatory school vaccinations all the time. The anti-vax movement has obviously been emboldened and strengthened in the last several years but I don't see any evidence to suggest that a majority of parents are now anti-vax.
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Oct 27, 2021 17:54
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haveblue posted:5-11 year olds aren't making their own medical decisions so I'd expect it to closely match the vaccination rates of their parents I could be wrong. That’s my prediction.
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Oct 27, 2021 17:57
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Professor Beetus posted:What makes you think anti-vax parents are the majority? I have no doubt that they will be a significant thorn in the side of getting vaccination numbers up but to say they are a majority of parents doesn't seem like something grounded in reality. Kids get mandatory school vaccinations all the time. The anti-vax movement has obviously been emboldened and strengthened in the last several years but I don't see any evidence to suggest that a majority of parents are now anti-vax.
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Oct 27, 2021 18:08
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Gio posted:There will be a not insignificant percentage of vaccinated adults who will refuse to vaccinate their children, either due to immunity from infection or because they don’t think it’s necessary. I certainly hope you're wrong in this case, but I'm sure you do too.  Forgive the twitter link (I'm not looking for follows lol, I just use twitter to yell at companies and post videos of my cat) but everyone could use a dose of pet tax today: https://twitter.com/MadDrBeetus/status/1451229395197186064?s=20
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Oct 27, 2021 18:10
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It sounds like early next week is when the CDC will meet to discuss the 5-11 vaccine. Everyone is assuming they will go forward with it, but I have to say I'm annoyed at how long it's taken since the data was made available. It feels like this could've been made more of a priority by the various governing bodies. Edit: Also seeing rumors about the shot being actually available by late next week, but we'll see I guess. The schools around here are already planning clinics at the elementary schools and expanding the junior high ones.
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Oct 27, 2021 19:00
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haveblue posted:5-11 year olds aren't making their own medical decisions so I'd expect it to closely match the vaccination rates of their parents They're not, but I suspect at least some portion of parents are only getting vaccinated because their work requires it, or something similar. And in the absence of a similar compelling reason to vaccinate their children, I'm not sure those parents will.
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Oct 27, 2021 19:06
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Does the US mandate vaccinations for school attendance? I think here in Ontario the chances of it being mandated for this school year are basically nil, but I imagine it's going to be a big provincial election issue, and there's a decent chance we'll have it added for September 2022.
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Oct 27, 2021 19:17
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Lager posted:It sounds like early next week is when the CDC will meet to discuss the 5-11 vaccine. Everyone is assuming they will go forward with it, but I have to say I'm annoyed at how long it's taken since the data was made available. It feels like this could've been made more of a priority by the various governing bodies. It's honestly blisteringly fast how quickly this had proceeded, hell how quickly all the vaccine approvals have proceeded. Pfizer submitted initial data the end of September, but didn't submit the full EUA until October 8th. That's less than three weeks from submission (and it's a lot of data to review. Don't forget it's not just trial results) to VRBPAC voting to approve it. I'd also imagine there was a conscious effort to not skip the expert panel review stage of the approval like they did with the full Pfizer approval a couple months back, as that added a bunch of fuel to the anti-vax/right-wing media fire over the vaccines being "rushed and unsafe".
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Oct 27, 2021 19:20
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enki42 posted:Does the US mandate vaccinations for school attendance? I think here in Ontario the chances of it being mandated for this school year are basically nil, but I imagine it's going to be a big provincial election issue, and there's a decent chance we'll have it added for September 2022. Yes but it's determined at state/local level what the requirements and exemptions are. edit: so I suspect what will happen with school vaccine mandates in the US is similar to what's happened with mask mandates and other precautions - bluer areas will require kids get shots after it's fully FDA approved, and redder areas won't. Fritz the Horse fucked around with this message at 19:27 on Oct 27, 2021 |
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Oct 27, 2021 19:21
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Lager posted:It sounds like early next week is when the CDC will meet to discuss the 5-11 vaccine. Everyone is assuming they will go forward with it, but I have to say I'm annoyed at how long it's taken since the data was made available. It feels like this could've been made more of a priority by the various governing bodies. I will remind this thread though that the AAP was telling the CDC and FDA all the way back in November 2020 that child vaccine trials must start now or there will be significant delay getting shots in kids arms. https://www.aappublications.org/news/2020/11/17/covidvaccinetrials111720 Those trials did not start until March 2021, well over 4 months after the warning. The only people to fault and blame for the length of time it's taken the child vaccines to be approved are the CDC and FDA. mod sassinator fucked around with this message at 19:48 on Oct 27, 2021 |
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Oct 27, 2021 19:45
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mod sassinator posted:edit: wrong thread Uh, that's not how it works and not what that article says: The article posted:The AAP is calling for manufacturers to include children in their COVID-19 vaccine trials and for federal officials to use a rigorous scientific process for reviewing vaccines The FDA and CDC don't run the trials, the manufacturers do. They just review the submitted data and decide on approval or not. They might provide broad non binding guidance on how those trials should be run for the data to be acceptable but that's about it. It's on Pfizer or Moderna or whoever to include children in clinical trials.
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Oct 27, 2021 19:59
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Mr Luxury Yacht posted:Uh, that's not how it works and not what that article says: Oh well in that case it perfectly excuses it and makes the situation we are in completely acceptable. You either have to criticize the FDA/CDC or the vaccine manufacturers. There is fault here no matter how it's tried to be spun or said. People delayed on action and children have been infected, died, and been maimed for life because of it. (and please, let's not start a 10 page derail again on how 'only' 500 kids have died and that well actually that's perfectly acceptable and we just have to live with it) This was preventable, this was warned and it was ignored. People in power at institutions and companies should be held responsible and accountable for their lack of action.
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Oct 27, 2021 20:19
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Professor Beetus posted:What makes you think anti-vax parents are the majority? I have no doubt that they will be a significant thorn in the side of getting vaccination numbers up but to say they are a majority of parents doesn't seem like something grounded in reality. Kids get mandatory school vaccinations all the time. The anti-vax movement has obviously been emboldened and strengthened in the last several years but I don't see any evidence to suggest that a majority of parents are now anti-vax. US parenting culture is broken, it's basically a right wing subculture at this point instead of something everyone does. Look at "mommy culture" vaxx rates in pregnant women, down in the 30s.
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Oct 27, 2021 20:48
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Dude half the problem is that antivaxxers infiltrated new mother groups. It's tied directly into the essential oil poo poo because it's used to sell mlm poo poo to new scared moms. Really it's directly linked to social media amplifying stuff in order to radicalize viewpoints. Healthcare pushes to follow a vaccine schedule but it doesn't help if some of the new mother support groups have massive antivaxxers or mlm marketers in it that actively lie to mother's and cause this, and the hospital unknowlly sends mom's to them. Other issue is lack of post birth care due to money, alot of babies don't get vaccinated because the parents can't get pediatric care or visits reliably. That's a whole nother can of worms. I realize this sounds snarky but it's not meant to be, it's a legitimate issue that's used to prey on new mothers or even worse scared single mothers and actively harms people. Made worse by the anti-abortion groups that prey on that population so much.
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Oct 27, 2021 21:53
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Also the only people with the community support to reproduce are pretty much already chuds, because churches/antivax mommy groups/Proud Boys/etc are the only activities outside of consuming and working that won't get stomped out relentlessly.
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Oct 27, 2021 21:56
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