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SpacePig posted:Opinion: genericizing old medical formulations means people might not spring for name-brand formulations of the same stuff. This is bad for patients. I guess there might be bad effects if a patient can only take the name-brand for some reason, but also everyone I've ever heard complain about not being able to take generics have been the biggest cranks who are convinced seed oil gives you toxins or whatever
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Sep 7, 2022 00:48
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he’s probably pissed with whoever wrote the headline
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Sep 7, 2022 00:49
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Subjunctive posted:he’s probably pissed with whoever wrote the headline engagement
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Sep 7, 2022 00:51
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generic meds can vary by like 20% in bioavailability and still carry the label. I had to adjust one of my meds’ dosages because of that, and two others are name-brand-no-substitute.
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Sep 7, 2022 00:52
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Subjunctive posted:he’s probably pissed with whoever wrote the headline Yeah the article isn’t as clear as it needs to be but does seem like it comes from a place of real concern. That headline and sun-headline though — lmao I wouldn’t be surprised if we found out the editor had a personal grudge against this dunce
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Sep 7, 2022 00:52
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Subjunctive posted:he’s probably pissed with whoever wrote the headline maybe after he got yelled at on Twitter. before that though he thanked the editor here: https://twitter.com/mikerosemdmph/status/1566967495264817160?s=21&t=FMQtBmHz1sTKSsGvVYmA7A
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Sep 7, 2022 00:52
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Professor Shark posted:Opinion: You should be scrapping by through life, leaping from one falling platform to another, just barely dodging car repair bills, dental for your kids, etc… and why that’s a good thing.
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Sep 7, 2022 01:34
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Subjunctive posted:he’s probably pissed with whoever wrote the headline Yeah this is my guess too, the guy seems to think all diabetes treatment should be free (or "zero-dollar copay", I will give them the benefit of the doubt there) and I'm guessing whoever wrote that headline went "hmm this article is boring, how can I get people really riled up so they hatepost it a bunch??" Shame Boy has issued a correction as of 02:35 on Sep 7, 2022 |
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Sep 7, 2022 02:32
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hobbesmaster posted:maybe after he got yelled at on Twitter. before that though he thanked the editor here: I mean, I probably would too? Like I'm not gonna publicly bitch out someone who I just worked with over something that, at the time, probably seemed like "just the kind of thing newspapers do" or otherwise something to raise privately, idk.
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Sep 7, 2022 02:34
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I know this is CSPAM and all but there is only a certain amount of Mad On The Internet I have to work with here and this just ain't in the budget, sorry, maybe next year
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Sep 7, 2022 02:36
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Retromancer posted:Hey, you're not seeing the big picture. Actually, it's three containers  https://www.youtube.com/watch?v=KUH5DvfJcCQ&t=27s Would love to live in a steel box in winter in Toronto
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Sep 7, 2022 02:47
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My favorite thing about recycling steel shipping containers into completely impractical houses is that the steel that would have otherwise been reclaimed by melting them down instead has to get dug out of the ground and refined
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Sep 7, 2022 06:59
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BonHair posted:Incidentally, her whole complex in Frederiksberg was bought by Blackstone and is now mostly empty 
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Sep 7, 2022 08:02
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Coolness Averted posted:Yeah, not sure if he's a dummy who can't communicate his actual advocacy of 'we need to do more' or if he's just concern trolling 'we can't actually do a good thing, because of bad things that also happen in the status quo' How long til he goes for a modest proposal defense
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Sep 7, 2022 08:35
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Shame Boy posted:My favorite thing about recycling steel shipping containers into completely impractical houses is that the steel that would have otherwise been reclaimed by melting them down instead has to get dug out of the ground and refined Steel mining is terrible the environment, too.
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Sep 7, 2022 08:39
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Subjunctive posted:Steel production is terrible the environment, too. Steel isn't mined, it's made out of iron. But yeah that's why recycling steel is actually useful and profitable compared to paper, cardboard, or most plastics where the process is often a net loss or close to it when you factor in transportation.
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Sep 7, 2022 09:52
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hobbesmaster posted:the author is having a normal one how much stock does mike rose have in insulin companies?
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Sep 7, 2022 10:09
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hobbesmaster posted:maybe after he got yelled at on Twitter. before that though he thanked the editor here:
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Sep 7, 2022 12:46
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Shame Boy posted:My favorite thing about recycling steel shipping containers into completely impractical houses is that the steel that would have otherwise been reclaimed by melting them down instead has to get dug out of the ground and refined My favorite thing is that they're not made for human habitation, but rather to meet the shipping requirements of a world that really doesn't like importing insects along with their TVs or whatever. Just doused in pesticide that would make any inhabitant sick. The solution? Rip up the wooden floor and put in a new floor and cover the walls with new walls, effectively building a new, smaller container within the larger container.
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Sep 7, 2022 13:39
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Splicer posted:I'm genuinely curious what recourse someone has on this. Like, if I wrote an article about how America keeps killing socialist countries and the headline was put up as "Socialism is doomed to failure -Splicer" I'd be pretty angry. not writing opinion pieces for right wing rags is probably a good start
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Sep 7, 2022 14:40
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Zvahl posted:not writing opinion pieces for right wing rags is probably a good start Hey maybe he didn't know. He's not very smart, he's a doctor after all.
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Sep 7, 2022 15:22
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Shame Boy posted:Hey maybe he didn't know. He's not very smart, he's a doctor after all. I’m sure this is the joke but for those that haven’t worked closely with physicians outside a direct patient care context: locking physicians into medical school+hospital campuses for a decade for training has exactly the impact you’d think Splicer posted:I'm genuinely curious what recourse someone has on this. Like, if I wrote an article about how America keeps killing socialist countries and the headline was put up as "Socialism is doomed to failure -Splicer" I'd be pretty angry. my understanding is that they’ll have signed something giving up some editorial control to be published like that. doctors may not understand the full ramifications of this as stated above so maybe wouldn’t have pushed back and said no edits or something. I mean just think how embarrassing it’d be if there was a typo, surely they wouldn’t change the meaning of the piece! hobbesmaster has issued a correction as of 15:57 on Sep 7, 2022 |
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Sep 7, 2022 15:52
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tokin opposition posted:I guess there might be bad effects if a patient can only take the name-brand for some reason, but also everyone I've ever heard complain about not being able to take generics have been the biggest cranks who are convinced seed oil gives you toxins or whatever
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Sep 7, 2022 16:21
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Zvahl posted:not writing opinion pieces for right wing rags is probably a good start 
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Sep 7, 2022 16:22
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Arsenic Lupin posted:Ask anybody with epilepsy or ADHD about the enormous difference switching generics can make in the effectiveness of the dose. Unfortunately, pharmacies are now changing the manufacturer of generics month-to-month based on availability and cost. for those that aren’t familiar, personally I’m just familiar with the concerta issue but others have similar problems: https://www.additudemag.com/medication/concerta/ quote:Concerta is available in both branded and generic versions. This causes a great deal of confusion because there are currently six different formulations that are designated methylphenidate ER and that come in the same odd dosage strengths of 18, 27, 36, and 54 mg caplets but only one of these is the authentic “branded generic” that is identical to the brand name Concerta. The other five products are quite inferior, and the FDA recently succeeded in downgrading two of these product’s quality ratings. there are basically two adhd stimulants - methylphenidate (Ritalin) and mixed amphetamine salts (adderall). there are like a half a dozen different extended release versions of each with patented delivery mechanisms. when the patent for a delivery mechanism expires a generic can be made with that delivery mechanism but that means that writing say “methylphenidate ER” is ambiguous. the chemical itself will be guaranteed to be correct but the release mechanism is not. this is the link that’s mentioned above btw: https://adhdrollercoaster.org/adhd-medications/authorized-generic-concerta-update/
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Sep 7, 2022 17:30
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Shame Boy posted:I feel like I should probably bite the bullet and buy a place instead of renting but also this is florida and by the time the mortgage is paid off I'm pretty sure it will rather literally be underwater sooo if the house you're buying in FL isn't built this year (2022) than it's gonna be uninsurable within 5. already anything over 15 is bulldozer time. expect your insurance to triple a couple times too, before they drop you You'd think because of climate change, or maybe hurricane threat right? because that's a reasonable reason to expect insurance prices have gon NOPE! It's because an idiot judge ruled that unlicensed contractors can do shoddy full-roof replacements on the insurance companies dime and also that the insurance companies have to pay the legal costs of the lawyer who sued them if they deny the claim. So lovely contractors get people to sign 'assignment of benefits' or whatever, pair up with lovely lawyers, sue because your shingles are 3 years old and must be replaced, hit them for like 40k in repairs and leave you with a freshly leaking roof. it's a hilariously stupid ruling, unique in the nation and whoops the completely expected and obvious thing happened: every insurer said 'gently caress this' and dropped the state.
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Sep 7, 2022 17:42
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I'm on Vyvanse and I don't have those problems  because it's not available as a generic yet and so is a loving pain in the rear end to deal with
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Sep 7, 2022 17:42
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There was and maybe still is the issue where manufacturers of generic methylphenidate kept getting their production licenses revoked for different quality issues.
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Sep 7, 2022 17:48
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Shame Boy posted:I'm on Vyvanse and I don't have those problems vyvanse is actually a straight prodrug, it actually should not have those issues when it goes generic
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Sep 7, 2022 17:53
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hobbesmaster posted:vyvanse is actually a straight prodrug Yeah I know, that's specifically why I'm on it. It's the only one that doesn't give me a sudden OH poo poo peak and then crash before the end of the day, since the requirement that it pass through the liver first means it kinda like, meters itself out better? Even the extended release stuff didn't do as good a job as this. hobbesmaster posted:, it actually should not have those issues when it goes generic Oh that's good to know, thanks 
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Sep 7, 2022 17:55
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pygmy tyrant posted:There was and maybe still is the issue where manufacturers of generic methylphenidate kept getting their production licenses revoked for different quality issues. In general the US is really lovely about CGMP compliance. Once a formulation is approved for the market, the system is set up almost entirely the way a Libertarian argues product regulation should work. The producer hires a 3rd party to audit their facilities and systems, and then out of their enlightened self interest the producer is expected to comply, because if they don't the end retailer or consumer is damaged, then the FDA asks for proof the company is doing things correctly, and if they can't properly prove it (mostly through the paperwork produced by the 3rd party auditor) they get shut down anywhere from between a quarter to forever. That's a pretty big incentive for a pharma giant to try and do the right thing. A toll blender making generic sunscreen or aspirin under someone else's label? Not so much. They're generally a fly-by-night if they're not dealing in a DEA/DOJ regulated substance or alcohol. Similarly if I'm paying a toll blender, I have their audit results and self certification to prove I did my due diligence, so as long as I show the FDA I'm using another vendor after the gently caress up, I'm allowed to get right back to market, with the only damage being consumers or retailers potentially rejecting my brand.
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Sep 7, 2022 18:11
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Coolness Averted posted:Steel isn't mined, it's made out of iron. yeah, 
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Sep 7, 2022 18:39
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Subjunctive posted:yeah, Oh I thought you just messed up on your phone or something because "steel mining is terrible the environment" sounds like drunkposting 
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Sep 7, 2022 18:43
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Shame Boy posted:Oh I thought you just messed up on your phone or something because "steel mining is terrible the environment" sounds like drunkposting no, just distracted-posting, my bad
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Sep 7, 2022 18:43
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https://twitter.com/OriginalFunko/status/1567939198849794048
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Sep 8, 2022 20:39
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WoW gold farming. You've invented WoW gold farming.
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Sep 8, 2022 23:05
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Animal-Mother posted:WoW gold farming. You've invented WoW gold farming. one of the weirdest historical details is how much money steve bannon made on that
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Sep 8, 2022 23:10
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Unless posted:one of the weirdest historical details is how much money steve bannon made on that Steve Bannon's entire history is full of bizarre poo poo like that. For another example, he sabotaged Biosphere 2. Dude's like the anti-forrest-gump.
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Sep 8, 2022 23:17
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lmao https://twitter.com/MikeSington/status/1567840888738676736 
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Sep 9, 2022 02:32
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FIGHT 93 REDIRECT
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