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PhazonLink posted:oh are those two supa bad now? As long as you don't overdose, it's safe though. All three of the main kinds of OTC painkillers (aspirin, acetaminophen, and ibuprofen/other NSAIDs) all have their own niches where they're better than the others, the NSAIDs are just more forgiving to overdose.
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# ? Dec 4, 2022 06:53 |
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# ? May 31, 2024 03:14 |
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PhazonLink posted:if alcohol and tobacco were discovered today they would both probably be banned. They did try banning alcohol and it failed miserably. For a number of reasons, but probably not least that indulging in alcohol probably predates civilisation.
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# ? Dec 4, 2022 08:59 |
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Ghost Leviathan posted:They did try banning alcohol and it failed miserably. For a number of reasons, but probably not least that indulging in alcohol probably predates civilisation. Home brewed beer is good. It used to be that the wife of the household made the beer in addition to her other jobs where they weren't shared with the menfolk (like tending fields). But now home brews are primarily made by guys. Anyway, the reason people made beer is its alcoholic properties killed many of the nastier bacteria that infested the rivers and streams of ancient lands caused by a lack of good sanitation infrastructure. Also beer tastes good and enough will get you drunk.
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# ? Dec 4, 2022 09:09 |
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BioEnchanted posted:IIRC Glitter was into sex tourism of places with laxer laws regarding ages. I remember stories of him being with underage girls at least. Gary Glitter was a paedo. Who moved to Cambodia where he could get easier access to kids with less consequences. He got busted there, paid blood money to the family of his victim(s), then moved to Vietnam, where the exact same thing happened, blood money and all. Last I heard, british authorities got him, and he is in jail.
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# ? Dec 4, 2022 09:12 |
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That’s a reasonable but common misconception. Most societies in the ancient world had access to fresh sources of water and knew how to treat it. People made beer and wine because they liked drinking.
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# ? Dec 4, 2022 09:17 |
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Yeah, it takes proper civilization before you've ruined all the drinkable water nearby.
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# ? Dec 4, 2022 09:30 |
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The class action lawsuit ads are all saying that acetaminophen during pregnancy causes ADHD and autism.
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# ? Dec 4, 2022 09:43 |
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"Small beer" was more like thin porridge with a low alcohol content than what we know as beer today. A thirst quencher that also provided some nutrition must have been pretty essential for laborers.
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# ? Dec 4, 2022 09:46 |
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Foxfire_ posted:The issue with paracetamol/acetaminophen/Tylenol is that there isn't a very large difference between a therapeutic dose and a toxic dose. There's about a 3x difference between a cure-your-headache dose and an occasionally-fatal-if-untreated dose. I’ve got to believe health literacy and a culture of inappropriate access to the medication has to be a contributor to harm-by-tylenol. In Australia we are seeing a steady uptake of acetaminophen toxicity being treated, or resulting in harm or death, but we’re not competing on any level to North America. Sure, part of that will be our smaller population, but we also cannot walk into a Walmart and leave with a literal bucket full of potential liver poison. I think the largest pack on our shelves is probably a 60 tablet box? If I grew up in a culture where they were doled-out like a fist-full of Skittles, maybe I wouldn’t register how dangerous they can be. And why would Mr Walmart be able to sell me something that can crash-course my liver? The consumer isn’t well informed, and is even less-well protected, but I think that’s a feature for you guys, not a bug? My family has delivered frontline medical support in a bunch of regions around Australia and couple in North America, and the relationship between self harm with meds (intentional or not) has a great deal to do with ease of access. Thank you for coming to my TED talk.
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# ? Dec 4, 2022 10:03 |
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We used to be able to buy non-prescription painkillers in bottles of 200+ here in the EU, but that was changed some years ago, exactly because of accidental/deliberate poisonings. Now you can only buy them in boxes of 20 and only one per customer.
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# ? Dec 4, 2022 10:15 |
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PuntCuncher posted:I’ve got to believe health literacy and a culture of inappropriate access to the medication has to be a contributor to harm-by-tylenol. I think the last bottle of ES Tylenol I bought (several years back) was 7.99 for 500 tablets? It went bad before I had used more than about a half dozen during it's shelf life which was about two years. Aspirin is similar (available in quantity, cheap, harmful), but at least gives off a pungent vinegar-esqe odor to warn you when it's no good. (versus people ingesting expired tylenol) "Doled-out like a fist-full of Skittles" is accurate for how some people consume them. There is piss-all awareness on the subject amongst the general population (turns out not a lot of people read the paperwork in the box), and the average person who needs 'em isn't likely to stop long enough to take heed of the warnings.
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# ? Dec 4, 2022 10:53 |
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Yeah I work in pharmacy and I have to deal with one or two 'hi my loved one took eight paracetamol what shall we do?' calls a year. They are all very startled when I tell them they need to call an ambulance.
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# ? Dec 4, 2022 13:56 |
Len posted:I'll never understand why tobacco isn't allowed to advertise but alcohol is In my country it is illegal to advertise for both. It's also illegal to make ads directed at children. KozmoNaut posted:We used to be able to buy non-prescription painkillers in bottles of 200+ here in the EU, but that was changed some years ago, exactly because of accidental/deliberate poisonings. I can see why, but it is still annoying that I can't by more than one box zyrtec at the time.
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# ? Dec 4, 2022 14:01 |
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Alhazred posted:In my country it is illegal to advertise for both. It's also illegal to make ads directed at children. Wait they've limited Zyrtec in your country? That shits 400 for $16 here
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# ? Dec 4, 2022 14:09 |
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HopperUK posted:Yeah I work in pharmacy and I have to deal with one or two 'hi my loved one took eight paracetamol what shall we do?' calls a year. They are all very startled when I tell them they need to call an ambulance. I read somewhere that acetaminophen suicides are quite common in the States too as they are a lot easier to get than sleeping pills.
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# ? Dec 4, 2022 14:26 |
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By popular demand posted:I read somewhere that acetaminophen suicides are quite common in the States too as they are a lot easier to get than sleeping pills. This seems wrong since I can just buy a big box of unisom Note: attempting to kill yourself with unisom will mostly make you frustrated
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# ? Dec 4, 2022 15:59 |
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By popular demand posted:I read somewhere that acetaminophen suicides are quite common in the States too as they are a lot easier to get than sleeping pills. Oh boy, an excruciating death over several days as your organs slowly fail in a process that’s largely irreversible after a certain point. Of all the ways to go
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# ? Dec 4, 2022 16:09 |
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Kit Walker posted:Oh boy, an excruciating death over several days as your organs slowly fail in a process that’s largely irreversible after a certain point. Of all the ways to go One time I had a young woman come into the pharmacy and she told me she'd taken - I think about 70 paracetamol tablets. That wasn't what was making her unwell right then, though. It was that they were the 'extra' kind with added caffeine. Poor thing could hardly sit still. The ambulance took her away, I really hope she came through.
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# ? Dec 4, 2022 16:17 |
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HopperUK posted:One time I had a young woman come into the pharmacy and she told me she'd taken - I think about 70 paracetamol tablets. That wasn't what was making her unwell right then, though. It was that they were the 'extra' kind with added caffeine. Poor thing could hardly sit still. The ambulance took her away, I really hope she came through. Out of sheer horrific curiosity, I just drank a 32 oz soda, so how many 32 oz sodas worth of caffeine is that?
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# ? Dec 4, 2022 16:34 |
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Rochallor posted:Out of sheer horrific curiosity, I just drank a 32 oz soda, so how many 32 oz sodas worth of caffeine is that? Energy drinks can go closer to 15-20mg/oz, and coffee can be in the high double digits, so it's less of those but still talking in the gallons range. Edge & Christian has a new favorite as of 16:44 on Dec 4, 2022 |
# ? Dec 4, 2022 16:41 |
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Rochallor posted:Out of sheer horrific curiosity, I just drank a 32 oz soda, so how many 32 oz sodas worth of caffeine is that? About 130 if I did the math right.
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# ? Dec 4, 2022 16:42 |
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Rochallor posted:Out of sheer horrific curiosity, I just drank a 32 oz soda, so how many 32 oz sodas worth of caffeine is that? There’s a PYF dangerous chemistry thread that has chemists, hobbyists, researchers, etc. that can answer this question in FAR more detail than you’d ever want, but it’s always a good read. Thread favorites are the vicious hell-broth chlorine trifluoride, and most things Dr Derek Lowe posts off of the “Things I Won’t Work With” blog. Here’s a quote to get you there! Icon Of Sin posted:From the “Media that didn’t age well” thread, mostly so I can quote myself to link it there
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# ? Dec 4, 2022 16:44 |
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Len posted:Wait they've limited Zyrtec in your country? That shits 400 for $16 here I once bought a 1500-pack of 200mg ibuprofen in Michigan. Can't remember what it cost, but it wasn't much.
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# ? Dec 4, 2022 16:58 |
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I don't think I've ever taken more than the recommended dosage on any kind of medicine (to the point of setting a timer to make sure I don't take something earlier), but I did once find myself weeping in the bathroom at a family gathering, and then looked at the various things I was taking to finally get rid of my "cold" and found out that depression is a common drug interaction side effect. That "cold" turned out to be seasonal allergies that for years I didn't realize were something you could take entirely different drugs to ameliorate than the stupid cold medicine that was just giving me the side effects!
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# ? Dec 4, 2022 18:59 |
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I took some anti-histamines a little while ago with orange juice because i happened to have a glass already on the go and had horrible waves of nausea afterwards. I looked up the side effects a little bit after and the very first note was "DO NOT TAKE WITH ORANGE JUICE". Luckily I just felt kinda lovely for a while and nothing bad happened but I had to laugh.
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# ? Dec 5, 2022 00:36 |
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Kit Walker posted:Oh boy, an excruciating death over several days as your organs slowly fail in a process that’s largely irreversible after a certain point. Of all the ways to go My dad used to take Vicodin 750s like candy, like House levels, and I was always afraid this would be the end result. I don’t know what he takes now but I’m pretty sure there isn’t any acetaminophen in it because he hasn’t said anything about getting his liver checked recently. screaden posted:I took some anti-histamines a little while ago with orange juice because i happened to have a glass already on the go and had horrible waves of nausea afterwards. I looked up the side effects a little bit after and the very first note was "DO NOT TAKE WITH ORANGE JUICE". Grapefruit juice does the same thing from what I was told. It was explained to me that you could be fine or it could be like you took 100x the amount of medication you did. Obsoletely Fabulous has a new favorite as of 00:47 on Dec 5, 2022 |
# ? Dec 5, 2022 00:44 |
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I watched the Jim Carrey movie Yes Man for some reason last night, and it felt like an extremely pre-recession movie in a lot of ways. The single biggest was that Carrey, a loan officer, just starts saying yes to every single loan application. This has nothing but positive consequences for everyone involved. People hear that Carrey will approve literally any loan and start lining up out the door for loans for things like idiotic business ideas and exotic motorcycles. The loans work out great for everyone: people are happier living their best lives, they all pay their loans on time making the bank a ton of money, and Carrey gets promoted to be some sort of unspecified banking big shot. The movie also has an underlying message of "do whatever makes you happy and the money will follow." After watching I checked the release date and it was actually December, 2008. So I guess it aged terribly immediately upon release.
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# ? Dec 5, 2022 00:58 |
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The Moon Monster posted:I watched the Jim Carrey movie Yes Man for some reason last night, and it felt like an extremely pre-recession movie in a lot of ways. The single biggest was that Carrey, a loan officer, just starts saying yes to every single loan application. This has nothing but positive consequences for everyone involved. People hear that Carrey will approve literally any loan and start lining up out the door for loans for things like idiotic business ideas and exotic motorcycles. The loans work out great for everyone: people are happier living their best lives, they all pay their loans on time making the bank a ton of money, and Carrey gets promoted to be some sort of unspecified banking big shot. The movie also has an underlying message of "do whatever makes you happy and the money will follow." The weird body roller skating thing at the end was an absolutely baffling inclusion and is now the only thing I remember about that movie.
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# ? Dec 5, 2022 01:03 |
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Here's another "modern technology solves an old problem" example. In 1976, The Sylvers had a big hit with "Hot Line". A song about a guy trying to reach a girl via telephone even going so far as to enlist the aid of the FBI and CIA. Obviously that would no longer be an issue today. https://www.youtube.com/watch?v=lwx64lD4m44
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# ? Dec 5, 2022 01:06 |
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The Moon Monster posted:I watched the Jim Carrey movie Yes Man for some reason last night, and it felt like an extremely pre-recession movie in a lot of ways. The single biggest was that Carrey, a loan officer, just starts saying yes to every single loan application. This has nothing but positive consequences for everyone involved. People hear that Carrey will approve literally any loan and start lining up out the door for loans for things like idiotic business ideas and exotic motorcycles. The loans work out great for everyone: people are happier living their best lives, they all pay their loans on time making the bank a ton of money, and Carrey gets promoted to be some sort of unspecified banking big shot. The movie also has an underlying message of "do whatever makes you happy and the money will follow." Well he made up for it with Fun with Dick and Jane e: gently caress me that was 2005 they were still reeling from the last huge dump my timeline is whack
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# ? Dec 5, 2022 02:13 |
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Mister Kingdom posted:Here's another "modern technology solves an old problem" example. This one's even more aged. Operator? What's that? https://www.youtube.com/watch?v=-qgnGH6Rg-E
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# ? Dec 5, 2022 02:14 |
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Absurd Alhazred posted:This one's even more aged. Operator? What's that? That part where he whimpers "...you can keep the dime" always made me confused. Is he calling from a payphone? This song is from 1972; more people had landlines then than indoor plumbing. Haha but having worked customer service, I can just imagine this from the operator's point of view. This guy wanting to make a call but uhhh he can't read the fuckin number and hey, let me tell you, I once had this friend Ray...
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# ? Dec 5, 2022 02:36 |
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credburn posted:That part where he whimpers "...you can keep the dime" always made me confused. Is he calling from a payphone? This song is from 1972; more people had landlines then than indoor plumbing. He's calling from the bar.
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# ? Dec 5, 2022 02:37 |
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https://1900hotdog.com/2022/12/upsetting-day-a-very-larry-christmas-%f0%9f%8c%ad/ Not that Larry the Cable Guy wasn’t bad in the first place, but did you know he had songs about wanting to sleep with teenagers too?
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# ? Dec 6, 2022 14:39 |
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bobjr posted:https://1900hotdog.com/2022/12/upsetting-day-a-very-larry-christmas-%f0%9f%8c%ad/ That guy is extra weird since his entire personality is a persona he tried out one day that took over his life, so everything he says on stage these days is probably filtered through what he imagines his current fans wants to hear. Not that that in any way excuses singing about wanting to sleep with teenagers, of course. This is what he looked and sounded like before he found that sleevless shirts and a redneck accent would lead to millions of dollars. https://www.youtube.com/watch?v=QdQtXqeXPuo
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# ? Dec 6, 2022 14:56 |
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The Moon Monster posted:I watched the Jim Carrey movie Yes Man for some reason last night, and it felt like an extremely pre-recession movie in a lot of ways. The single biggest was that Carrey, a loan officer, just starts saying yes to every single loan application. This has nothing but positive consequences for everyone involved. People hear that Carrey will approve literally any loan and start lining up out the door for loans for things like idiotic business ideas and exotic motorcycles. The loans work out great for everyone: people are happier living their best lives, they all pay their loans on time making the bank a ton of money, and Carrey gets promoted to be some sort of unspecified banking big shot. The movie also has an underlying message of "do whatever makes you happy and the money will follow." I completely forgot about that movie but I remember thinking basically exactly that when I saw it all those years ago
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# ? Dec 6, 2022 15:02 |
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Offler posted:That guy is extra weird since his entire personality is a persona he tried out one day that took over his life, so everything he says on stage these days is probably filtered through what he imagines his current fans wants to hear. Not that that in any way excuses singing about wanting to sleep with teenagers, of course. Perhaps Daniel Whitney was the dream and Larry was the man
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# ? Dec 6, 2022 18:04 |
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Obsoletely Fabulous posted:Grapefruit juice does the same thing from what I was told. It was explained to me that you could be fine or it could be like you took 100x the amount of medication you did. Grapefruit juice interacts with a shocking number of medications, and it does so in different ways. Some meds will not be metabolized right and cause the levels in your body to be too high, some meds will be rendered ineffective. I work with developmentally disabled folks many of which are on seizure medications or old psychiatric medication regimens they've had for 50+ years that are at risk of serious health issues from that insidious citrus. It should come with a skull and crossbones on it and a firmly worded warning from the surgeon general.
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# ? Dec 6, 2022 23:48 |
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It's common advice to take psychedelic mushrooms with grapefruit juice to enhance their potency.
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# ? Dec 7, 2022 00:12 |
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# ? May 31, 2024 03:14 |
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Yeah, it's probably why Hunter S. Thompson liked grapefruit so much. His standard breakfast included two grapefruits, and in Fear and Loathing in Las Vegas he was eating it constantly.
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# ? Dec 7, 2022 00:28 |