Pingui posted:

As this is a slow news day, I have taken the liberty of posting this opinion piece in full, because I've read it 4 times and I am unsure if he is trying to make the point I am reading (italization not mine):

It seems to me that he is saying the plague normalization is a good thing?

quote:

It may be decades before our attention is emancipated from the slavery of a necessary but unhealthy health vigilance.

Pingui posted:

lmao, this poo poo sucks.

SardonicTyrant posted:

the joke was listening to my mom do the same to someone else.

PoundSand posted:

plays out exactly how a pessimist would expect,

goodnight mooned posted:

I have covid. first time. literally can't smell poo poo. might eat an onion for lunch later

thuly posted:

Finding Novavax info in my state is like pulling teeth, swear to God I might have to road trip to get the good juice.

Asproigerosis posted:

Woah anyone heard of this covid thing? Sounds crazy.

Oh wait it's 2023 and this is what my hospital is sending out again for some reason, despite covid having been over for a year now? Strange.

Asproigerosis posted:

Woah anyone heard of this covid thing? Sounds crazy.

Oh wait it's 2023 and this is what my hospital is sending out again for some reason, despite covid having been over for a year now? Strange.

fosborb posted:

lol what's the right answer

PoundSand posted:

I recall getting into several fights in 2020 with friends over the idea that the second Biden walks into office people will stop caring about Covid/kids in cages/literally every progressive issue he won’t do poo poo about and it’s crazy how fast that stuff got memory holed. like fortunately it wasn’t Twitter arguments so no one who knew me assumed I was a trump supporter for saying mainstream democrats only care about these issues as the opposition party but it’s so bizarre to me that this sort of discussion comes up, plays out exactly how a pessimist would expect, then upcoming election year the same people will step on the same rakes going to bat for the idea that either party cares about anything other than their rich friends and their insider trading portfolios.

jisforjosh posted:

I'm assuming vaccines.gov is completely unreliable for locating Novavax? It claims every CVS and Walgreens near me has it but it's not an option while scheduling

icantfindaname posted:

I wonder how this compares to Clinton in the 1990s. I wasn't around but my understanding is he ran as mildly center-left in 1992, and then the rightward turn was explained away as triangulating towards the Republicans out of necessity. This time around it feels more like there's much more explicit memory-holing and in a year or two Biden will have always been a center-right figure, will have been elected in 2020 as a center-right figure, and all the articles about how he is the most progressive president since FDR will have been taken offline

Baddog posted:

Yah, one of my kids friends plays hockey seriously, and caught it repeatedly in those first 2 years, apparently from the rink. It is kinda weird, because a huge ventilated space, right.

But here is a study saying that the air is stagnant right at head height.
https://ysph.yale.edu/public-health...door-ice-rinks/

Also maybe something with the cold air in there making the virus more stable. But now you got me worried about how applicable this is to climbing gyms and those tennis domes.

(hope you got an easy one and get better soon!)

quote:

The closer quarters of wintertime living do, in fact, contribute to an increase in viral transmission. However, that doesn’t explain the initial wave of illness that kicks off the start of the flu season each year. New research suggests the cause may be found within the human nose -- specifically, that colder temperatures have an adverse effect on the efficacy of the immune response that takes place inside of the nose.

The study, from researchers at Massachusetts Eye and Ear hospital and Northeastern University, appeared last December in the Journal of Allergy and Clinical Immunology. According to their findings, a crucial frontline immune response, which occurs within the nasal passages, becomes significantly less effective when the nose itself gets cold. At issue are microscopic structures known as extra-cellular vesicles, or EVs. In the presence of certain threats, including bacteria and some respiratory viruses, billions of EVs are released into the mucus of the nose. There, they surround and kill the invaders.

According to this new research, a decrease of just 9 degrees Fahrenheit in the tissue temperature of the nasal passages cut the number of EVs available to respond to a threat by more than 40%. The colder temperature also caused changes to the composition of the EVs that reduced their efficacy. The researchers theorize that all of this hampers the body’s ability to fight off respiratory viruses and leads to the annual winter surge.

We can’t change the weather, but we can protect ourselves. This includes an annual flu shot, which this year is proving to be a good match to the circulating virus. (And no, it’s not too late to get one.) The masks so many of us have stockpiled are also a useful tool. Not only do they offer a physical barrier against the airborne droplets that can carry viral particles, but they also create a warm microclimate. This can help keep the nose’s immune defenses in fighting form.

jisforjosh posted:

I'm assuming vaccines.gov is completely unreliable for locating Novavax? It claims every CVS and Walgreens near me has it but it's not an option while scheduling

icantfindaname posted:

It's not available anywhere yet right?

PoundSand posted:

https://www.youtube.com/watch?v=fxAIn2OOpwI

BusError posted:

I'm just about through my bottle of Enovid and I'd like to replace it with some iota carrageenan spray instead of dropping another jillion dollars on something that by all accounts works less well. US goons who have purchased some, where'd you get it? I've pretty skeptical of getting anything that really needs to be the genuine article from Amazon, but that's all I've found via googling...

quote:

Overall, neither published data nor results from studies presented herein provide any evidence for local intolerance or toxicity, when 0.12% iota-carrageenan is applied intranasally / topically or by inhalation supporting the beneficial safety profile described for iota-carrageenan. There were no nonclinical findings that would preclude the safe administration of 0.12% iota-carrageenan to humans for treatment of respiratory viral infections.

Asproigerosis posted:

https://www.bbc.com/news/health-66818046 posted:

Covid: Over-65s called for jabs as hospital cases rise
People 65 and over in England are being urged to get a top-up booster vaccine against Covid at a time when more people are coming into hospitals with the virus.
(..)
For most people, catching Covid, while unpleasant, is less risky. Past Covid infections and vaccines have trained the immune system to stop severe illness, even if it cannot stop infection.
(..)

Poppers posted:

Sometimes enjoying yourself means not wearing a mask

corona familiar posted:

I thought they buffed the area of effect in a major release over a year ago

mags posted:

Computer Serf posted:

does the Carrageenan goop accumulate in the lungs or does it drip into the gastrointestinal tubes?

i was hyped on some of the research on an effective prophylactic nasal spray, but i saw there’s been a long history of a questionable safety profile with carrageenans as a food additive.

this website summarizes some of the history:
https://www.cornucopia.org/researcher-bias-carrageenan-controversy/

Thomson AW & Fowler EF. (1981) “Carrageenan: a review of its effects on the immune system.” Agents and Actions, 11:265–273. https://link.springer.com/article/10.1007/BF01967625
Carrageenans (kappa, lambda and iota) can markedly suppress immune responses both in vivo and in vitro. The mechanism responsible for carrageenan-induced immune suppression is believed to be its selective cytopathic effect on macrophages. This property of carrageenan has led to its adoption as a tool for analyzing the role of these cells in the induction and expression of immune reactivity.

Author affiliations: Department of Pathology, University of Aberdeen (Aberdeen, Scotland, UK) and the Department of Histopathology, St Bartholomew’s Hospital (London, UK)


Tobacman JK, Walters KS. 2001. “Carrageenan-induced inclusions in mammary myoepithelial cells.” Cancer Detect Prev., 25(6):520-6. PMID: 12132872. https://pubmed.ncbi.nlm.nih.gov/12132872/
The purpose of this investigation was to characterize the ultrastructural changes that occur in mammary myoepithelial cells (MMEC) following exposure in tissue culture to low concentrations of lambda-carrageenan, a sulfated polysaccharide commonly used as a food additive. Carrageenan appeared to enter the cells by membrane-associated endocytic vesicles and accumulate in endosomes and lysosomes. Unusual lamellar inclusions were identified within lysosomes of the MMEC, and lysosomal vacuolation arose in association with the inclusions. The observed changes appeared to lead to destruction of the MMEC by release of proteolytic enzymes from the distorted lysosomes, similar to the process observed in lysosomal storage diseases.

Author affiliations: Department of Internal Medicine, University of Iowa (Iowa City, USA).

quote:

Carrageenan (CGN) is a common food additive that has been widely used for decades as a gelling, thickening and stabilizing agent. Carrageenan has been proven safe for human consumption; however, there has been significant confusion in the literature between CGN and the products of intentional acid-hydrolysis of CGN, which are degraded CGN (d-CGN) and poligeenan (PGN). In part, this confusion was due to the nomenclature used in early studies on CGN, where poligeenan was referred to as "degraded carrageenan" (d-CGN) and "degraded carrageenan" was simply referred to as carrageenan. Although this nomenclature has been corrected, confusion still exists resulting in misinterpretation of data and the subsequent dissemination of incorrect information regarding the safe dietary use of CGN. The lack of understanding of the molecular weight distribution of CGN has further exacerbated the issue. The significant differences in chemistry, manufacture, and protein reactivity of CGN versus d-CGN and PGN are reviewed, in addition to the in vivo toxicological profiles of CGN, d-CGN, and PGN. As CGN cannot be hydrolyzed to PGN in vivo, concerns over the use of CGN as a food additive are unfounded, particularly since current studies support the lack of oncogenic and tumorigenic activity of CGN in humans.

Poppers posted:

Maybe instead of being dismissive you should consider why so many people enjoy doing things without masks. Perhaps there is a reason…?

(USER WAS PUT ON PROBATION FOR THIS POST)

Oracle posted:

Order from a supplier in Canada that ships to the US. This company was recommended on Reddit's zero-covid community (looks like they built in the cost of shipping into the price they charge, which is currently 20 bucks. Pre-covid prices for a bottle of this was 12.99CA, for an example). This is a bog-standard online checkout page and seems totally legit, though there is no option for expedited shipping.

speng31b posted:

lmao

BusError posted:

Ah nice, wound up buying from that site earlier today after scrounging around for any other sources and coming up dry. I thought they looked about as legit as I could hope for, so glad to hear they appeared that way to your eyes, too. Will update here if I got scammed!

Asproigerosis posted:

I caught a glimpse of an n95 next to a brown paper bag and I'm sure if I had stopped to read it would have been talking about reusing the same n95 for months.

UnknownMercenary posted:

Okay at the risk of sounding really dumb but are you not supposed to do that? I mean I've been slowly going through a box of N95s since last year just by reusing as much as possible and only replacing if they get soggy or the bands snap, but I work in food service, not in health care.

Pingui posted:

The updated Novavax has not been approved yet, there is an FDA (potential approval) meeting the 22nd.

RandolphCarter posted:

I can’t believe a thread title would lie to me

Baddog posted:

My cousin has gone all anti-vax on me. Thought he was a pretty smart guy, but now he's sending me Pierre Kory links.

Pierre is pretty smart, he's blaming allllll the long covid symptoms on the vaccine. Even the brain fog. These symptoms can pop up months and months after you get the shot! Sometimes they won't show up until after you are infected with covid, lol. "Or a close exposure to a high-spike protein producing, (generally recently vaccinated) individual". I guess this is where the shedding spikes nonsense comes from.

I don't even know what to respond. I guess just "what the gently caress, don't be a dumbass, let your immunocompromised mom get the new vaccine".