capitalism.png: Living Wage as a Service (LWaaS)

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RandolphCarter: Jul 30, 2005

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# ? Sep 24, 2023 04:34

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# ? May 23, 2024 15:56

Rock Puncher: Jul 26, 2014

Harik posted:

ahh, so the main problem here is you have no idea what the luddites were about or why they were correct and will always remain correct no matter what happens with technology.

Yep, I know that someone had a name with Ludd in it or something and popular culture makes it seem like they would have taken our iPhones away if they had the chance, which I assume is not correct but it's reasonable to me that someone might qualify it with an asterisk given that

# ? Sep 24, 2023 04:35

Jazerus: May 24, 2011

Harik posted:

lmao.

governments fund medical R&D, not pharmacuticals. Then the government hands off the last mile testing to them, and their marketing budget for dick pills dwarfs any other expendature.

it's just handjobs to pharmacy execs because when you give someone a bunch of money they then in turn fund your campaign.

this is flatly not true. the research that comes out of academia guides industry in terms of picking its cellular targets and making guesses as to how to affect them but is rarely enough to even begin picking a good drug candidate family to work with let alone having it be as simple as "professor jerkoff figured out this molecule is great at doing x, then the pharma company did the clinical trials for it". there is a very large expenditure of time and effort and money in between any kind of academic work and someone putting a pill in their mouth, a lot of it happening before any kind of clinical trials to figure out how to even translate the academic work into something relevant to drugs. even the "last mile testing" can be humongously expensive btw but it's not all that's being done by the companies in 99% of cases.

i think pharma as an industry is corrosive and lovely and results in a lot of needless pain and death for patients due to cost being a gate on treatment, and a lot of needlessly duplicated scientific work in the fields where there's a lot of competition because they're all gonna screen the same kinds of molecules and come to similar conclusions about them, but you are falling for a very old and shallow narrative if you honestly believe that drug discovery labs in pharma companies don't exist lol. you can read things written by scientists that work there to get an idea of the scale of operations and money involved, you don't have to just believe the pharma company press releases or w/e.

anyway governments should be the ones funding the drug discovery, yes, imo. they aren't right now tho except maybe china

# ? Sep 24, 2023 04:44

Harik: Sep 9, 2001; From the hard streets of Moscow
First dog to touch the stars; Plaster Town Cop

Jazerus posted:

this is flatly not true. the research that comes out of academia guides industry in terms of picking its cellular targets and making guesses as to how to affect them but is rarely enough to even begin picking a good drug candidate family to work with let alone having it be as simple as "professor jerkoff figured out this molecule is great at doing x, then the pharma company did the clinical trials for it". there is a very large expenditure of time and effort and money in between any kind of academic work and someone putting a pill in their mouth, a lot of it happening before any kind of clinical trials to figure out how to even translate the academic work into something relevant to drugs. even the "last mile testing" can be humongously expensive btw but it's not all that's being done by the companies in 99% of cases.

i think pharma as an industry is corrosive and lovely and results in a lot of needless pain and death for patients due to cost being a gate on treatment, and a lot of needlessly duplicated scientific work in the fields where there's a lot of competition because they're all gonna screen the same kinds of molecules and come to similar conclusions about them, but you are falling for a very old and shallow narrative if you honestly believe that drug discovery labs in pharma companies don't exist lol. you can read things written by scientists that work there to get an idea of the scale of operations and money involved, you don't have to just believe the pharma company press releases or w/e.

anyway governments should be the ones funding the drug discovery, yes, imo. they aren't right now tho except maybe china

and each and every one of those steps has enormous government subsidies.

# ? Sep 24, 2023 04:53

Coolness Averted: Feb 20, 2007; oh don't worry, I can't smell asparagus piss, it's in my DNA

GO HOGG WILD!
🐗🐗🐗🐗🐗

Rock Puncher posted:

Yep, I know that someone had a name with Ludd in it or something and popular culture makes it seem like they would have taken our iPhones away if they had the chance, which I assume is not correct but it's reasonable to me that someone might qualify it with an asterisk given that

Yeah, it's one of those funny 'history written by the victors' situations. The Luddites were a labor movement against mill owners having all the power and forcing people into worse jobs for worse pay.
If the situation was "Hey I just bought a new piece of equipment that doubles productivity, I'm gonna run it at 75% speed to avoid unsafe conditions and pay you the same daily wage" they would not have been smashing the looms.
Instead it was "We're going to pay pennies on the dollar for your children to get mangled in this mill. If you don't like it, there's plenty of other poors who will gladly throw themselves into the maim-o-tron for my profits."

They lost, so now we use the term to refer to technophobes.

# ? Sep 24, 2023 05:05

Shame Boy: Mar 2, 2010

My favorite thing pharma companies don't mention when talking about how much new drugs cost is that a bunch of that cost is actually just opportunity cost, as in, "if we took the money we spent and instead just let it sit and accumulate in the stock market for the time it took to develop the drug, we would have made billions of dollars!"

# ? Sep 24, 2023 05:15

Coolness Averted: Feb 20, 2007; oh don't worry, I can't smell asparagus piss, it's in my DNA

GO HOGG WILD!
🐗🐗🐗🐗🐗

Shame Boy posted:

My favorite thing pharma companies don't mention when talking about how much new drugs cost is that a bunch of that cost is actually just opportunity cost, as in, "if we took the money we spent and instead just let it sit and accumulate in the stock market for the time it took to develop the drug, we would have made billions of dollars!"

Yeah, and their figures also generally assume optimal investment, instead of just comparing to the market itself.

# ? Sep 24, 2023 05:32

Peanut President: Nov 5, 2008; by Athanatos

Rock Puncher posted:

I think putting an * on luddites were right is fair, I don't actually know that much about the luddites other than they were definitely right then and still are now because of material conditions. But if resources and production was owned communally rather than individually I think the * starts to gain value. You could potentially argue that technology would still be mostly destructive, but again, there's a solid argument for saying technology and automation might not be that bad if the goal isn't to maximise consumption and increases in numbers.

The luddites were not anti-technology they were anti-rich. They smashed the factories not because "unga bunga technology bad" but because they were driven from their high-skilled high-paying craftsmen jobs into wage slavery. The technology allowed them to make more fabric for cheaper prices making more wealth but the wealth was transferred to the factory owner instead of them.

Please read a loving book.

# ? Sep 24, 2023 05:39

Peanut President: Nov 5, 2008; by Athanatos

the average cspam poster is worse read every year i swear to christ

# ? Sep 24, 2023 05:40

PostNouveau: Sep 3, 2011; VY till I die; Grimey Drawer

Peanut President posted:

Please read a loving book.

Never

# ? Sep 24, 2023 05:41

Paladinus: Jan 11, 2014; heyHEYYYY!!!

Peanut President posted:

the average cspam poster is worse read every year i swear to christ

The only book I'll ever need to read is the one where every page is completely random and the book itself is infinitely long.

# ? Sep 24, 2023 05:45

Coolness Averted: Feb 20, 2007; oh don't worry, I can't smell asparagus piss, it's in my DNA

GO HOGG WILD!
🐗🐗🐗🐗🐗

I'm here for capitalism.png not daskapitol.epub

# ? Sep 24, 2023 05:45

Milo and POTUS: Sep 3, 2017; I will not shut up about the Mighty Morphin Power Rangers. I talk about them all the time and work them into every conversation I have. I built a shrine in my room for the yellow one who died because sadly no one noticed because she died around 9/11. Wanna see it?

Why does the blue beetle have 8 limbs

# ? Sep 24, 2023 05:51

Bald Stalin: Jul 11, 2004; Can't post for 12 hours!

Harik posted:

and each and every one of those steps has enormous government subsidies.

Nope the small pharma startup I worked at was 100% venture capital then IPO/shareholder $. The only subsidy would have been a small grant to the scientists at a university lab that figured out how heart muscle works before the same scientists pitched it to venture capitalists.

Those scientists are now multi millionaires, the drug was approved which is hella rare. But the workers in their labs at that uni doing the pre drug development biology work never saw a dime.

Not all the science happened at the uni though. Most of the papers were authored and published by the private pharma company scientists after venture capital got involved. They ramped up the science 100x

Bald Stalin has issued a correction as of 05:54 on Sep 24, 2023

# ? Sep 24, 2023 05:52

mawarannahr: May 21, 2019

Jazerus posted:

this is flatly not true. the research that comes out of academia guides industry in terms of picking its cellular targets and making guesses as to how to affect them but is rarely enough to even begin picking a good drug candidate family to work with let alone having it be as simple as "professor jerkoff figured out this molecule is great at doing x, then the pharma company did the clinical trials for it". there is a very large expenditure of time and effort and money in between any kind of academic work and someone putting a pill in their mouth, a lot of it happening before any kind of clinical trials to figure out how to even translate the academic work into something relevant to drugs. even the "last mile testing" can be humongously expensive btw but it's not all that's being done by the companies in 99% of cases.

i think pharma as an industry is corrosive and lovely and results in a lot of needless pain and death for patients due to cost being a gate on treatment, and a lot of needlessly duplicated scientific work in the fields where there's a lot of competition because they're all gonna screen the same kinds of molecules and come to similar conclusions about them, but you are falling for a very old and shallow narrative if you honestly believe that drug discovery labs in pharma companies don't exist lol. you can read things written by scientists that work there to get an idea of the scale of operations and money involved, you don't have to just believe the pharma company press releases or w/e.

anyway governments should be the ones funding the drug discovery, yes, imo. they aren't right now tho except maybe china

Pfizer reported revenues of $100.3 billion for full year 2022 for the first time in the company�s 174-year history, reflecting 30 percent operational growth, while fourth quarter revenues were $24.3 billion, reflecting 13 percent operational growth. Fourth-quarter operational growth was primarily driven by key primary care and specialty care brands, partially offset primarily by lower revenues for certain other products. Quarterly reported diluted earnings per share (EPS) was $0.87, up 48 percent year-over-year. Quarterly adjusted diluted EPS[1] was $1.14, up 45 percent year-over year.

Full-year revenues increased 23 percent year-over-year and Pfizer reported full-year diluted EPS of $5.47, up 42 percent year-over-year, and adjusted diluted EPS1 of $6.58, up 62 percent year over year. Both EPS figures represent all-time highs for the company.

Pfizer�s 2022 performance is a testament to the company�s commitment to fulfilling its purpose of delivering breakthroughs that change patients� lives and creating value for Pfizer shareholders.

# ? Sep 24, 2023 06:22

mawarannahr: May 21, 2019

this thread is the best thread in cspam.

# ? Sep 24, 2023 06:22

stringless: Dec 28, 2005; keyboard ⌨️ cowboy

Milo and POTUS posted:

Why does the blue beetle have 8 limbs

Six legs. Or six arms.

# ? Sep 24, 2023 06:27

jeebus bob: Nov 4, 2004; Festina lente

mawarannahr posted:

Pfizer’s 2022 performance is a testament to the company’s commitment to fulfilling its purpose of delivering breakthroughs that change patients’ lives and creating value for Pfizer shareholders.

Humans don't speak like this, try again

# ? Sep 24, 2023 07:40

GotLag: Jul 17, 2005; 食べちゃダメだよ

Peanut President posted:

Please read a loving book.

I have read all seven books, and the script for The Cursed Child

# ? Sep 24, 2023 08:28

Ruffian Price: Sep 17, 2016

jeebus bob posted:

Humans don't speak like this, try again

Yes that was partially the point of that post

# ? Sep 24, 2023 08:35

Rock Puncher: Jul 26, 2014

welp gently caress my mission is now to read exactly 1 book and never not know something ever again lest someone makes me read another one

# ? Sep 24, 2023 08:41

tokin opposition: Apr 8, 2021; I don't jailbreak the androids, I set them free.

WATCH MARS EXPRESS (2023)

Having memorized all letters and punctuation I have learned every book to ever exist by memory, it's just a matter of selecting from the set of words from books that actually exist and are useful

Owned libs

# ? Sep 24, 2023 09:27

stringless: Dec 28, 2005; keyboard ⌨️ cowboy

Rock Puncher posted:

welp gently caress my mission is now to read exactly 1 book and never not know something ever again lest someone makes me read another one

Sad to say you need to read two books:

What They Teach You at Harvard Business School and What They Don't Teach You at Harvard Business School

# ? Sep 24, 2023 09:59

Rigged Death Trap: Feb 13, 2012; BEEP BEEP BEEP BEEP

Bald Stalin posted:

Nope the small pharma startup I worked at was 100% venture capital then IPO/shareholder $. The only subsidy would have been a small grant to the scientists at a university lab that figured out how heart muscle works before the same scientists pitched it to venture capitalists.

Those scientists are now multi millionaires, the drug was approved which is hella rare. But the workers in their labs at that uni doing the pre drug development biology work never saw a dime.

Not all the science happened at the uni though. Most of the papers were authored and published by the private pharma company scientists after venture capital got involved. They ramped up the science 100x

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426978/

Governments regularly subsidize pharma companies to pursue things with lower RoI instead of making, oh for example, proprietary blends of insulin analogues.

All large and critical industries are neck deep in government subsidy.

# ? Sep 24, 2023 10:47

Biplane: Jul 18, 2005

tokin opposition posted:

Having memorized all letters and punctuation I have learned every book to ever exist by memory, it's just a matter of selecting from the set of words from books that actually exist and are useful

Owned libs

One weird trick BIG BOOK doesn't want you to know about!

# ? Sep 24, 2023 11:09

Bald Stalin: Jul 11, 2004; Can't post for 12 hours!

Rigged Death Trap posted:

Governments regularly subsidize pharma companies to pursue things with lower RoI instead of making, oh for example, proprietary blends of insulin analogues.

All large and critical industries are neck deep in government subsidy.

Yes? Not always was the point. Not all pharma is big and government subsidized. There was no drug to help people with the disease so probably some return on investment, it was open heart surgery, heart transplant, and death. Now there's a drug for it, at least.

Bald Stalin has issued a correction as of 11:19 on Sep 24, 2023

# ? Sep 24, 2023 11:15

Peanut President: Nov 5, 2008; by Athanatos

Rock Puncher posted:

welp gently caress my mission is now to read exactly 1 book and never not know something ever again lest someone makes me read another one

you should probably just eat a shotgun instead

(USER WAS PUT ON PROBATION FOR THIS POST)

# ? Sep 24, 2023 12:05

Mushika: Dec 22, 2010

Peanut President posted:

The luddites were not anti-technology they were anti-rich. They smashed the factories not because "unga bunga technology bad" but because they were driven from their high-skilled high-paying craftsmen jobs into wage slavery. The technology allowed them to make more fabric for cheaper prices making more wealth but the wealth was transferred to the factory owner instead of them.

Please read a loving book.

This is a seriously good post.

# ? Sep 24, 2023 13:28

Milo and POTUS: Sep 3, 2017; I will not shut up about the Mighty Morphin Power Rangers. I talk about them all the time and work them into every conversation I have. I built a shrine in my room for the yellow one who died because sadly no one noticed because she died around 9/11. Wanna see it?

Jimmy's 6 months in hospice is really getting to him

# ? Sep 24, 2023 13:35

Fat-Lip-Sum-41.mp3: Nov 15, 2003

Peanut President posted:

The luddites were not anti-technology they were anti-rich. They smashed the factories not because "unga bunga technology bad" but because they were driven from their high-skilled high-paying craftsmen jobs into wage slavery. The technology allowed them to make more fabric for cheaper prices making more wealth but the wealth was transferred to the factory owner instead of them.

Please read a loving book.

never opposed to technology. only opposed to the unequal distribution of its benefits. capitalists were in fact forced to hire back hand weavers when their power looms were destroyed, saving thousands of people from starvation.

even people who know this will forget because the lie is told relentlessly in all media, in every context imaginable.

Fat-Lip-Sum-41.mp3 has issued a correction as of 13:39 on Sep 24, 2023

# ? Sep 24, 2023 13:37

Paladinus: Jan 11, 2014; heyHEYYYY!!!

Words change meaning.

# ? Sep 24, 2023 13:49

Mushika: Dec 22, 2010

Fat-Lip-Sum-41.mp3 posted:

never opposed to technology. only opposed to the unequal distribution of its benefits. capitalists were in fact forced to hire back hand weavers when their power looms were destroyed, saving thousands of people from starvation.

even people who know this will forget because the lie is told relentlessly in all media, in every context imaginable.

Whoosh.

# ? Sep 24, 2023 14:01