trashy owl posted:

It's me, almost nobody! Just barely a somebody.

Baddog posted:

Very few people have no covid *and* no vaccine. And pretty sure we've all inhaled *some* virus at this point. Just not enough to get a real infection going.

So very hard to get a real, honest "baseline" anymore for efficacy comparisons. poo poo, its hard to establish even a homogenous sample of any kind for studies going forward. Maybe they should just measure the level of antibodies at the start of the study (but against which variant??).

Tzen posted:

the past weeks of talking with family friends that run and others in the running community lol the loving horror stories from covid infections they opened up to me upon hearing that i recently recovered from covid. these are people i've talked to on a regular basis for years, but only now do they tell me, the only loving guy still masking, how bad covid hit them. i never knew that any of them had covid prior.

Tzen posted:

the past weeks of talking with family friends that run and others in the running community lol the loving horror stories from covid infections they opened up to me upon hearing that i recently recovered from covid. these are people i've talked to on a regular basis for years, but only now do they tell me, the only loving guy still masking, how bad covid hit them. i never knew that any of them had covid prior.

"it took me about 2 years to finally feel back to normal" "i was in the hospital for about a week" "i had to cancel all my races last year" "i posted on strava about an injury, but really post covid i just couldn't run"

RandolphCarter posted:

12 hours after booster: my joints are sore and I am very cold. first reaction this bad.

RandolphCarter posted:

trip report 3: just puked for the first time in years. new slut juice got hands.

euphronius posted:

it’s clear the government is going to do nothing .

Platystemon posted:

That one play where all the people are turning to rhinoceroses, but they don’t like being rhinoceroses, but they won’t tell you that till you’re also a rhinoceros, and they’re capable of communicating and choose not to.

emgeejay posted:

Pittsburgh Fentanyl Cloud posted:

NPR had a 'how to act when you return to the office' segment a few days ago and they were saying "don't be a downer", eg don't talk about covid or being sick. lmao

Oracle posted:

lol that dude is confusing the black plague with the Spanish flu.

Pingui posted:

Confusing the common summer flu with the endemic plague.

https://www.theguardian.com/society/2023/sep/29/parents-in-england-urged-to-ensure-children-get-mmr-vaccine-amid-uptake-drop posted:

Parents in England urged to ensure children get MMR jab amid uptake drop
MMR vaccination levels at lowest since 2010-11, figures show, with uptake of other key jabs also too low

Parents are being urged to get their children vaccinated against measles, mumps and rubella (MMR) after a “worrying” drop in uptake of key vaccines.

Figures from NHS England and the UK Health Security Agency (UKHSA) show 92.5% of children had had the first dose of the MMR jab at five years old by 2022-23, the lowest since 2010-11.

The proportion of five-year-olds who had had the second jab by 2022-23 was 84.5%, also the lowest level since 2010-11.

Vaccination programmes across England failed to meet the uptake recommended by the World Health Organization (WHO) for the year 2022-23. WHO recommends that, nationally, at least 95% of children should be inoculated for diseases that can be stopped by vaccines, in order to prevent outbreaks.

NHS data showed no routine vaccine programme met the threshold during the 12-month period. Dr Gayatri Amirthalingam, a consultant medical epidemiologist at UKHSA, said the downward trend was a “serious concern”.
(..)

trashy owl posted:

Oh that's fair I did get the initial vaccine series and the first booster round. My spouse is immunocompromised so we rarely go out and when we do we are always masked up. No slips to drink water or whatever, we plan around excursions. Since there is no sterilizing vaccine we haven't gotten more shots, especially with how short the "window of protection" has proven to be. Possible to live a cool, good, happy, and fulfilling life without taking chances. Doubt there's any protection left from those vaccine series and while they weren't the actual virus, maybe the immune system has a sort of "cold storage".

Apologies for misunderstanding

https://www.eurosurveillance.org/content/10.2807/1560-7917.ES.2023.28.39.2300489 posted:

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Overall, 33 of 38 residents tested positive by LFD or PCR (AR = 87%), of whom 19 were symptomatic (Figure 1, Table 1). Four resident cases recorded low oxygen saturation and nine required healthcare attendance (GP consultation or ambulance attendance) including one resident who was hospitalised overnight. Two resident cases died within 16 days of symptom onset; these deaths were considered unrelated to COVID-19 and occurred after their COVID-19 symptoms resolved. No cases were eligible for antiviral treatment, but two residents were prescribed antibiotics for suspected secondary infections. By 13 September (24 days after the outbreak started), 17 symptomatic residents had recovered, with none still unwell. Thirteen symptomatic residents had recovered within 14 days of symptom onset.
(..)

(..)
The AR in this setting was substantially higher than that seen in nine UK care homes that experienced outbreaks in December 2021 to January 2022; the early period in which the Omicron variant circulated in the UK (23%) [13], although it was similar to one care home outbreak during early circulation of the Delta variant (82%) [14]. This suggests high transmissibility, although enhanced testing was undertaken in this outbreak specifically because of the reported high number of cases. Therefore, the AR observed is subject to selection bias and may not be typical of all care home outbreaks involving the BA.2.86 variant as the AR in care homes may vary due to a range of factors [2].

The hospitalisation rate among residents was lower than that reported in care home outbreaks during early circulation of the Omicron variant in December 2021 to January 2022 (11%) [13] and Delta variants (17%) [14]. Although the care home reported that the symptoms had a greater impact on the day-to-day life of residents and staff compared with their previous outbreaks, it is reassuring that there was no notable increase in the most severe outcomes of hospitalisation and death associated with BA.2.86 [13,14]. Nonetheless, hospitalisation rates in care homes are very context-dependent, therefore these comparisons may not be generalisable to other settings.

The high vaccination rate in the care home and lack of substantial vaccine effect against infection in this outbreak 4 months after a booster dose suggests notable immune evasion. This is not unexpected as we have seen rapid waning of VE against infection and mild disease with other vaccines and previous Omicron subvariants [15]. While the numbers were too small for any precise assessment of VE, the point estimate against symptomatic infection 4 months after a dose was similar to that observed with previous Omicron variants [16]. With previous variants, VE against severe disease resulting in hospitalisation has been considerably higher than against infection, and this is likely to also be the case with BA.2.86 [17].

Statistical assessment indicated that the LFD predominantly used in this outbreak had non-inferior sensitivity to detect BA.2.86 compared with previous SARS-CoV-2 Omicron strains [12]. However, LFD performance tends to be strongly associated with viral load, and stratified analysis of a larger sample would provide a more unbiased comparison.
(..)

https://www.washingtonpost.com/opinions/2023/09/28/cdc-isolation-guidance-covid-protection/ posted:

The Checkup With Dr. Wen: The CDC needs to change its covid guidance

The end-of-summer increase in covid-19 infections has brought renewed attention to the Centers for Disease Control and Prevention’s isolation guidance. These outdated recommendations must be revised, as they disincentivize testing, sow confusion and fail to achieve the most important objective of protecting vulnerable individuals.
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To me, the most compelling reason for the CDC to change its recommendations is that they are not being followed, even by conscientious people.
(..)
Adding to the challenge of interpreting the current guidance is that it only applies to people who are asymptomatic or who have mild symptoms. Those with moderate illness — defined as any shortness of breath — are supposed to isolate for a full 10 days. Once again, this adds to complexity and is not likely followed by much of the public.

I think the recommendations can be simplified by shifting the focus from a blanket isolation policy for any individuals with covid to tailored guidance based on who these individuals interact with.
(..)
The Biden administration recently announced it will issue another round of free covid-19 home tests. That’s terrific, and I hope people take advantage of them. Those vulnerable to severe outcomes should take tests if they are symptomatic because they need early antiviral treatment if they are infected. And those around these high-risk individuals should have ample tests to help prevent transmitting the virus to their loved ones.

Accepting that covid-19 is endemic requires adjusting our approach to it. The path forward must emphasize safeguarding the vulnerable while minimizing societal disruption. Changing isolation guidance is a crucial component, along with targeting boosters and treatments for high-risk individuals.

Pillowpants posted:

Wastewater Data

RandolphCarter posted:

this post has angered the shot as my arm is now sore and stiff. hope it fades before I go back to work tomorrow, I need that muscle to lift poo poo.

Pingui posted:

Leana Wen posted:

And those around these high-risk individuals should have ample tests to help prevent transmitting the virus to their loved ones.

euphronius posted:

wens solution seems to be you are on your own, good luck

Pittsburgh Fentanyl Cloud posted:

drunk driving is endemic and all drivers should calibrate their risk tolerance. If you're scared, stay off the roads.

euphronius posted:

we could make it illegal to have covid ?

shazbot posted:

I feel like like we’re going to see the opposite on issues like drunk driving, where we will continue to make more and more laws in the name of more cops

Pittsburgh Fentanyl Cloud posted:

There was massive opposition to drunk driving laws, seatbelt laws, etc when they were pushed through over the objections of the general public. There's no way in hell anything like that could happen today.

thedavid posted:

So I got covid a short while back, due to other people coming to the wife's office while knowing they were sick, and it was pretty rough. First time getting it. I've been getting back to the gym with the help from great folks in this thread that have posted some good advice.

But I had another run-in with covid since, and I just need a place to vent about it.
(..)
Just let me loving work from home. I've done it since 2020 now, only coming in when absolutely necessary. There were people on the phone in the workshop meeting via teams anyway, so it wasn't like we lost anything from being remote. Paying for a bunch of flights over from the EU while not paying for promotions, certifications, etc this year is also mindblowingly stupid.

Pingui posted:

minimizing societal disruption

Pingui posted:

Plague Island doubling down on the brand.