[Pestilence] https://youhavetoliveyour.life/

The Something Awful Forums > Discussion > C-SPAM > [Pestilence] https://youhavetoliveyour.life/

(Thread IKs: PoundSand)

Snowglobe of Doom: Mar 30, 2012; sucks to be right

The aged care facilities here in Australia are getting whacked by covid again:

Twitter link

Meanwhile the news media is starting to realise something might be happening and is publishing articles about how a new covid wave might be "approaching"

https://www.abc.net.au/news/2023-11-01/covid-cases-rise-updated-facts/103044762
Cloth mask, lol
E: I just noticed that the ear strap is tangled in her earring

# ? Nov 1, 2023 15:05

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# ? May 26, 2024 15:02

deadwing: Mar 5, 2007

WrasslorMonkey posted:

Just a little psychic damage from the Musk thread to start your morning

I like the scare caps on MONTANA

# ? Nov 1, 2023 15:06

Pittsburgh Fentanyl Cloud: Apr 7, 2003

Pingui posted:

Pure psycho poo poo.

I suppose ethics aren't inherently good.

The English are a particularly vile people

# ? Nov 1, 2023 15:10

WrasslorMonkey: Mar 5, 2012

deadwing posted:

I like the scare caps on MONTANA

Ever been there?

# ? Nov 1, 2023 15:11

Jort Fortress: Mar 3, 2005

Shady Amish Terror posted:

It is, ironically, probably easier to get through the forms if you're uninsured if number 3 is a factor. Lucky Ducky strikes again

I went back through and marked "uninsured" and it let me sign up, lol. But I foolishly didn't say that I was Covid positive, so I'm only getting some rapid tests.

# ? Nov 1, 2023 15:45

Rochallor: Apr 23, 2010; ふっっっっっっっっっっっっｃｋ

WrasslorMonkey posted:

Just a little psychic damage from the Musk thread to start your morning

It's literally impossible to reconcile this belief with "what are you wearing a mask for?" If you literally think covid is a government bio-weapon why aren't you trying not to get it?

# ? Nov 1, 2023 15:49

Zugzwang: Jan 2, 2005; You have a kind of sick desperation in your laugh.; Ramrod XTreme

Rochallor posted:

It's literally impossible to reconcile this belief with "what are you wearing a mask for?" If you literally think covid is a government bio-weapon why aren't you trying not to get it?

Their strategy when they thought it was a Chinese bioweapon was to immediately surrender, OP

# ? Nov 1, 2023 15:52

Bruce Hussein Daddy: Dec 26, 2005; I testify that there is none worthy of worship except God and I testify that Muhammad is the Messenger of God

I'll never understand that one. Ok, Tony comes out tomorrow and says "I admit it. I invented covid in Montana" He's put on trial and will be in prison for the rest of his life.

Now what.

# ? Nov 1, 2023 15:55

Pittsburgh Fentanyl Cloud: Apr 7, 2003

Covid is no big deal, just a cold, and also we need to put Nasty Tony in jail forever for inventing it.

# ? Nov 1, 2023 15:56

Zugzwang: Jan 2, 2005; You have a kind of sick desperation in your laugh.; Ramrod XTreme

The enemy won't stop shooting at us! This sucks!

*climbs out of trench, starts walking across No Man's Land toward Applebee's*

# ? Nov 1, 2023 16:31

Why Am I So Tired: Sep 28, 2021

Question for anyone who got asked to upload a video on test2treat - a) did you? b) were you able to email your way out of it? (aka "My camera doesn't work?")

# ? Nov 1, 2023 16:32

WrasslorMonkey: Mar 5, 2012

Rochallor posted:

It's literally impossible to reconcile this belief with "what are you wearing a mask for?" If you literally think covid is a government bio-weapon why aren't you trying not to get it?

Concerning.

# ? Nov 1, 2023 16:34

Why Am I So Tired: Sep 28, 2021

We've always had bioweapons.

# ? Nov 1, 2023 16:42

empireofcrime: Nov 3, 2015; The crimes of this guilty land can never be purged away but with blood.

Zugzwang posted:

Their strategy when they thought it was a Chinese bioweapon was to immediately surrender, OP

The clearest admission I've seen was a chud who acknowledged it was a bioweapon and then basically said it will kill some and some will survive and that was that.

# ? Nov 1, 2023 16:46

Precambrian Video Games: Aug 19, 2002

VA cohort study says Paxlovid doesn't reduce long COVID risk, but...

quote:

Design:
Retrospective target trial emulation study comparing matched cohorts receiving nirmatrelvir�ritonavir versus no treatment.

Setting:
Veterans Health Administration (VHA).

Participants:
Nonhospitalized veterans in VHA care who were at risk for severe COVID-19 and tested positive for SARS-CoV-2 during January through July 2022.

Intervention:
Nirmatrelvir�ritonavir treatment for acute COVID-19.

Measurements:
Cumulative incidence of 31 potential PCCs at 31 to 180 days after treatment or a matched index date, including cardiac, pulmonary, renal, thromboembolic, gastrointestinal, neurologic, mental health, musculoskeletal, endocrine, and general conditions and symptoms.

Results:
Eighty-six percent of the participants were male, with a median age of 66 years, and 17.5% were unvaccinated. Baseline characteristics were well balanced between participants treated with nirmatrelvir�ritonavir and matched untreated comparators. No differences were observed between participants treated with nirmatrelvir�ritonavir (n = 9593) and their matched untreated comparators in the incidence of most PCCs examined individually or grouped by organ system, except for lower combined risk for venous thromboembolism and pulmonary embolism (subhazard ratio, 0.65 [95% CI, 0.44 to 0.97]; cumulative incidence difference, −0.29 percentage points [CI, −0.52 to −0.05 percentage points]).

So reduced risk of stroke is just about the only significant long-term benefit, albeit in an older male cohort (but it seems unlikely that a younger, healthier cohort would have fared any differently, no?). Some commentary here:

quote:

The study suggests that otherwise healthy people infected with COVID might be wasting their time if they take Paxlovid to ward off long-term symptoms, said lead researcher Dr. George Ioannou, director of hepatology with the VA Puget Sound Health Care System in Seattle.

Paxlovid (nirmatrelvir-ritonavir) is typically intended for COVID-19 patients who are at high risk of dying or landing in the hospital, because they have existing health problems that make a severe infection more likely.

"If the only reason you are taking Paxlovid is because you think it will prevent you from developing complications of COVID-19, then maybe you should think twice about that," Ioannou said.

Studies have shown that Paxlovid can reduce the risk of death or hospitalization from a new COVID infection, researchers said in background notes.

But about 1 in 5 COVID-19 survivors aged 18 to 62 and 1 in 4 who are 65 or older develop one or more lingering symptoms from their initial infection, researchers said.

Many are known collectively as long COVID, and they can linger for weeks, months and even years.

"The effectiveness of Paxlovid in ameliorating the acute adverse events of COVID-19 in appropriate patients is fairly well-established," Ioannou said. "Now we're thinking more long term. Beyond those first 30 days, is there any continuing ongoing benefit of Paxlovid?"

Using records kept by the U.S. Veterans Health Administration, researchers identified 9,593 vets diagnosed with COVID-19 and treated with Paxlovid between January and July 2022.

The team then tracked the vets' health records for six months after their COVID-19 infection, to see if they developed any of a set of 31 health problems that have been identified as potential post-COVID conditions.

These included diseases of the heart, lungs, kidneys, digestive system, brain and muscles, as well as mood disorders like depression or anxiety and general problems like fatigue and erectile dysfunction.

As a last step, researchers matched the Paxlovid-treated veterans to others that had COVID but weren't treated with Paxlovid, to see if the drug made any difference in warding off long COVID symptoms.

Only one type of post-COVID health problem -- blood clots -- appeared to occur less often after Paxlovid treatment, results showed. These included blood clots of the veins as well as pulmonary embolisms.

"Those thromboembolic events have been some of the most consistently linked to COVID of all the post-COVID conditions, even in the early days of the pandemic when nobody knew anything about long COVID," Ioannou said.

Doctors had been hopeful that limiting the severity of a COVID infection would reduce the risk of developing long COVID, said Dr. William Schaffner, a professor of infectious diseases and preventive medicine at Vanderbilt University in Nashville, Tenn.

"I think we have to go back to the notion that we'd better get ourselves vaccinated, because the data indicate that vaccines reduce the risk of long COVID," Schaffner said. "Treatment might help prevent your evolution into more serious disease, but there's no evidence here that it provides a substantial benefit against developing long COVID."

Instead, these results might indicate that long COVID is caused by subtle effects from a COVID infection that aren't necessarily tied to how severe a person fell ill, said Dr. Fernando Carnavali, an internist at Mount Sinai Hospital in New York City.

Carnavali pointed to a recent University of Pennsylvania study that suggested some of the neurological and cognitive symptoms of long COVID, such as "brain fog," are linked to lower serotonin levels in these patients.

The study -- published recently in Cell -- suggested that serotonin is reduced because of remnants of the SARS-CoV-2 virus remnants that linger in the gut following infection.

"If this is caused by residual viral particles, what would be the role of an antiviral medication like Paxlovid?" Carnavali asked.

He recommended that people confused by conflicting data about COVID and long COVID talk to their doctor or a specialist.

"We will continue to see studies that perhaps contradict themselves, and this is just natural in the first stages of long COVID research and treatment," Carnavali said. "What you need is somebody to curate that information for you because it will continue to be like this and we will have information that is contradicting."

Ah well, nevertheless. Maybe there's hope for that new(er) Japanese antiviral Ensitrelvir/Xocova? Except it doesn't seem likely to become available outside of Japan anytime soon or ever?

e: re the last bolded point, there's a UK trial using remdesivir for 100-odd really long COVID patients (2+ years of symptoms, yeesh).

Precambrian Video Games has issued a correction as of 16:54 on Nov 1, 2023

# ? Nov 1, 2023 16:49

Zugzwang: Jan 2, 2005; You have a kind of sick desperation in your laugh.; Ramrod XTreme

empireofcrime posted:

The clearest admission I've seen was a chud who acknowledged it was a bioweapon and then basically said it will kill some and some will survive and that was that.

People who say this kind of thing always think it won't be them.

# ? Nov 1, 2023 16:55

SardonicTyrant: Feb 26, 2016; BTICH IM A NEWT
熱くなれ夢みた明日を
必ずいつかつかまえる
走り出せ振り向くことなく
&

Has anyone used both the 6500QL and 7500 series respirators from 3M? Which have you found more comfortable?

# ? Nov 1, 2023 16:58

Pittsburgh Fentanyl Cloud: Apr 7, 2003

empireofcrime posted:

The clearest admission I've seen was a chud who acknowledged it was a bioweapon and then basically said it will kill some and some will survive and that was that.

things just happen to people and no one can do anything about any of it OP. that's life!

# ? Nov 1, 2023 17:00

Pingui: Jun 4, 2006; WTF?

FuturePerfect VideoGames posted:

VA cohort study says Paxlovid doesn't reduce long COVID risk, but...

So reduced risk of stroke is just about the only significant long-term benefit, albeit in an older male cohort (but it seems unlikely that a younger, healthier cohort would have fared any differently, no?). Some commentary here:

Ah well, nevertheless. Maybe there's hope for that new(er) Japanese antiviral Ensitrelvir/Xocova? Except it doesn't seem likely to become available outside of Japan anytime soon or ever?

e: re the last bolded point, there's a UK trial using remdesivir for 100-odd really long COVID patients (2+ years of symptoms, yeesh).

It would be more accurate to say the study didn't see a statistically significant effect in the cohort. I posted the study a few days back with this comment:

Pingui posted:

The results are interesting, but I am not a big fan of the count starting at day 31, though I can understand why they did it. Mainly because CVD outcomes tend to happen within those first 30 days. It should be noted that these are non-hospitalized at the day or day after of testing. It should also be noted that a lot of the negative results come down to the confidence interval, potentially indicating an underpowering (see graphic).
"Effectiveness of Nirmatrelvir�Ritonavir Against the Development of Post�COVID-19 Conditions Among U.S. Veterans"

# ? Nov 1, 2023 17:21

Why Am I So Tired: Sep 28, 2021

A timeless, relevant video

https://twitter.com/chrisburke/status/1240014593830903809?lang=en

It's kind of cute how people were so outraged about this. The official policy of the most progressive president since FDR is that it's your fault if you die lol.

# ? Nov 1, 2023 17:21

Gunshow Poophole: Sep 14, 2008; OMBUDSMAN
POSTERS LOCAL 42069; Clapping Larry

FuturePerfect VideoGames posted:

VA cohort study says Paxlovid doesn't reduce long COVID risk, but...

Ah well, nevertheless. Maybe there's hope for that new(er) Japanese antiviral Ensitrelvir/Xocova? Except it doesn't seem likely to become available outside of Japan anytime soon or ever?

I mean, OK, but also

That guy posted:

"The effectiveness of Paxlovid in ameliorating the acute adverse events of COVID-19 in appropriate patients is fairly well-established,"

end of list.

This study is targeted at a specific outcome/timeline that is irrelevant to the obvious positive benefit of gettin paxed up immediately, it should not dissuade you from doing so. It may be unfortunate that there are no significant different outcomes at 31+ days but... if you're 20? 40? 80? percent less likely to be dead, who cares.

I'm also reading your post uncharitably because unfortunately any "negative" or "non-positive" outcome of studies like this will be interpreted and run with as even more reasons to not take the efficacious treatment at all.

Gunshow Poophole has issued a correction as of 17:26 on Nov 1, 2023

# ? Nov 1, 2023 17:22

Chamale: Jul 11, 2010; I'm helping!

Funny prank: Tell someone that he should wear a mask around his teammates while he's sick. He actually fell for it! What a chump!

quote:

Several players played cards in the back of the plane, a common pastime for those who ply their craft in America's pastime. Mac Scherzer, who was dealing with a stomach bug, was one of those players. This, Jacob deGrom decided, provided the perfect opportunity to pull off an epic prank. DeGrom discreetly asked the flight assistant, Missy, to tell Scherzer to wear his mask if he's going to play cards so that no one else would get sick. Missy, per deGrom's direction, told Scherzer the request was coming from the Rangers manager, Bruce Bochy.

"He was probably cussing me out," Bochy laughed. "He actually wore it. He was respectful with everything. He put it on."

"He wore it the whole freaking flight," said a teammate, who was only comfortable speaking about this very serious prank on the condition of anonymity. "Three hours. It was hysterical. Whole flight he's wearing it. We're all cracking up. He had no idea. No idea."

If Scherzer was actually sick with something contagious, this "prank" might have contributed to their winning the World Series.

# ? Nov 1, 2023 17:54

Fansy: Feb 26, 2013; I GAVE LOWTAX COOKIE MONEY TO CHANGE YOUR STUPID AVATAR GO FUCK YOURSELF DUDE; Grimey Drawer

Good morning pax hodlers!!!! Yesterday my bag was worth $0, now it's nearly $5,000!

# ? Nov 1, 2023 17:54

Precambrian Video Games: Aug 19, 2002

Pingui posted:

It would be more accurate to say the study didn't see a statistically significant effect in the cohort. I posted the study a few days back with this comment:

Fair enough, I need to read it more closely. I figured you would have posted it but search + hazy recollection of a few hundred posts I skimmed through on mobile to catch up failed me.

Gunshow Poophole posted:

I mean, OK, but also

end of list.

This study is targeted at a specific outcome/timeline that is irrelevant to the obvious positive benefit of gettin paxed up immediately, it should not dissuade you from doing so. It may be unfortunate that there are no significant different outcomes at 31+ days but... if you're 20? 40? 80? percent less likely to be dead, who cares.

I'm also reading your post uncharitably because unfortunately any "negative" or "non-positive" outcome of studies like this will be interpreted and run with as even more reasons to not take the efficacious treatment at all.

? I didn't say or imply not to take pax. Even the lead author's quote isn't making a recommendation for or against, more saying to think twice if your only goal is not to get long COVID.

Personally I would take it again because reduced strokes and the result from the sadly canceled clinical trial where literally nobody who took pax was dead from any cause after 6 months are good enough for me, and pax mouth is tolerable.

# ? Nov 1, 2023 17:59

Bruce Hussein Daddy: Dec 26, 2005; I testify that there is none worthy of worship except God and I testify that Muhammad is the Messenger of God

Chamale posted:

this "prank"

I read the whole article and I don't get it. As in, I can't even squint my eyes and understand the "prank"/"joke". What am I missing?

# ? Nov 1, 2023 18:03

Baddog: May 12, 2001

Rochallor posted:

It's literally impossible to reconcile this belief with "what are you wearing a mask for?" If you literally think covid is a government bio-weapon why aren't you trying not to get it?

I've heard "it's not the same people who think it's a bioweapon and who also say it's just a cold" (ehhhh, I think it usually is!). But musk here is a perfect example of someone who is holding both thoughts simultaneously.

I guess they can also have the doublethink that any weapon that comes out of china sucks. Even though in that case they are also undoubtedly afraid of china and want to quadruple defense spending to protect us from "communists".

# ? Nov 1, 2023 18:03

Precambrian Video Games: Aug 19, 2002

Bruce Hussein Daddy posted:

I read the whole article and I don't get it. As in, I can't even squint my eyes and understand the "prank"/"joke". What am I missing?

The prank is lying to make a guy wear a mask for three hours. That's it.

# ? Nov 1, 2023 18:04

Chamale: Jul 11, 2010; I'm helping!

Bruce Hussein Daddy posted:

I read the whole article and I don't get it. As in, I can't even squint my eyes and understand the "prank"/"joke". What am I missing?

Needing to wear a mask is inconvenient and awful, so he pranked his teammate by telling him the boss wants him to wear a mask so his teammates don't get sick!

# ? Nov 1, 2023 18:15

shazbot: Sep 20, 2004; Ah, hon, ya got arby's all over my acoustic wave machine.

Well props to the guy for wearing it without a fuss. Just goes to show most people will accomodate if you just ask them to and mask mandates are a good thing even if it pisses off 10% of people.

# ? Nov 1, 2023 18:17

Pittsburgh Fentanyl Cloud: Apr 7, 2003

Jacob DeGrom is a certified lunatic

# ? Nov 1, 2023 18:17

Bruce Hussein Daddy: Dec 26, 2005; I testify that there is none worthy of worship except God and I testify that Muhammad is the Messenger of God

FuturePerfect VideoGames posted:

The prank is lying to make a guy wear a mask for three hours. That's it.

Chamale posted:

Needing to wear a mask is inconvenient and awful, so he pranked his teammate by telling him the boss wants him to wear a mask so his teammates don't get sick!

Baseball players are the dumbest of all pro athletes. "lol he wore his seatbelt the whole car ride lmfao"

# ? Nov 1, 2023 18:30

Pittsburgh Fentanyl Cloud: Apr 7, 2003

Bruce Hussein Daddy posted:

Baseball players are the dumbest of all pro athletes. "lol he wore his seatbelt the whole car ride lmfao"

Also they were all hosed up on amphetamines for a century until the league banned the practice in the late 90s

# ? Nov 1, 2023 18:31

TehSaurus: Jun 12, 2006

TehWife�s pax order was also successful. Now we�re wondering how long until we can do it again since more is better

# ? Nov 1, 2023 18:40

Chamale: Jul 11, 2010; I'm helping!

Pittsburgh Fentanyl Cloud posted:

Also they were all hosed up on amphetamines for a century until the league banned the practice in the late 90s

It was a memo that said "We have to test you guys for coke and amphetamines now, but we're not going to test for steroids :v:

# ? Nov 1, 2023 18:42

havelock: Jan 20, 2004; IGNORE ME; Soiled Meat

Why Am I So Tired posted:

Question for anyone who got asked to upload a video on test2treat - a) did you? b) were you able to email your way out of it? (aka "My camera doesn't work?")

I uploaded one this morning - they just want name and dob. I haven't received any other messages from them yet, though. I'll let you know if I hear back.

# ? Nov 1, 2023 18:58

Phlag: Nov 2, 2000; We make a special trip just for you, same low price.

My test2treat doctor said that state law (Maryland) requires a telephone call to begin any sort of treatment. The phone tag was a bit obnoxious, but it was extremely quick and painless once we actually connected. Other states might have similar requirements that would require more than just filling out a form or sending an email to get the prescription.

# ? Nov 1, 2023 19:19

tuyop: Sep 15, 2006; Every second that we're not growing BASIL is a second wasted; Fun Shoe

SardonicTyrant posted:

Has anyone used both the 6500QL and 7500 series respirators from 3M? Which have you found more comfortable?

I use my 6500QL any time I don�t need to talk. it�s my go-to winter, cycling and general PPE mask because it�s very comfy for me and easy to pop on and off with the latch.

haven�t tried a 7500 though

# ? Nov 1, 2023 19:20

veepfake: Oct 21, 2005

Why Am I So Tired posted:

A timeless, relevant video

https://twitter.com/chrisburke/status/1240014593830903809?lang=en

It's kind of cute how people were so outraged about this. The official policy of the most progressive president since FDR is that it's your fault if you die lol.

at least she goes "wait, is that how i really feel about it" instead of make it policy

# ? Nov 1, 2023 19:21

tuyop: Sep 15, 2006; Every second that we're not growing BASIL is a second wasted; Fun Shoe

TehSaurus posted:

TehWife�s pax order was also successful. Now we�re wondering how long until we can do it again since more is better

hell yeah get it

# ? Nov 1, 2023 19:36

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# ? May 26, 2024 15:02

maxwellhill: Jan 5, 2022

Phlag posted:

My test2treat doctor said that state law (Maryland) requires a telephone call to begin any sort of treatment. The phone tag was a bit obnoxious, but it was extremely quick and painless once we actually connected. Other states might have similar requirements that would require more than just filling out a form or sending an email to get the prescription.

ah, mystery solved. thanks and good work

# ? Nov 1, 2023 19:58

The Something Awful Forums > Discussion > C-SPAM > [Pestilence] https://youhavetoliveyour.life/

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