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Powershift
Nov 23, 2009


Quit enjoying something the way you like it because it's not the way i like it :argh:

Be gone, beef snobs, BE GONE!

Powershift fucked around with this message at 09:11 on Mar 2, 2017

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Powershift
Nov 23, 2009


Goes great with a little bit of ketchup.

Powershift
Nov 23, 2009


If you're not taking bites straight out of the cow, you ain't poo poo.

Powershift
Nov 23, 2009


The best steak i ever had was prime rib at the back of a little casino in mesquite nevada.

It was 2pm and the prime rib dinner just started when i got there. i got it and it was probably an inch and a half thick and the size of the plate. had to be 50oz of prime rib, and it was so buttery and cooked so perfectly all the way through almost like it was sous vide. it filled the plate, so the mashed potatoes came in their own bowl on the side. It was also $11, which was nuts.

I didn't poo poo for like 3 days. i had to take a nap in the car at 3 in the afternoon before carrying on to vegas.

I stopped in there a few years later for the same thing and it was like a tv dinner, just 100% disappointment.

Powershift
Nov 23, 2009


grab a mask and hide in his bushes.

Powershift
Nov 23, 2009


Yu-Gi-Ho! posted:

No. Uber's been sued too many times to pull that poo poo.

It's a company called Deliv. The contract contradicts itself in a few different ways too. :v: I didn't sign it, but I have a copy of it.

You say that, but they keep doing piles of illegal poo poo.

Powershift
Nov 23, 2009




:catstare:

e:for you muricans, that's 52*f in the day to -2*f at night

Powershift fucked around with this message at 08:39 on Mar 5, 2017

Powershift
Nov 23, 2009


slidebite posted:

I know it's been happening since, like, forever, but I'm getting annoyed with companies lowering the weight/volume of product more and more while keeping prices the same and making no note on the package for the consumer to notice.

Latest catch: Pringles. Historically 160 gram can, now 148 grams. 10% less so physically it looks almost the same (You'd need them side by side to notice) but same selling price. I understand costs go up, but you can bet they'd change the label and mention it on a package if they go the other way like :siren: "EXTRA VALUE 10% MORE!!! SAME LOW PRICE!!!" :siren: but silent going the other way.

Also, before anyone shits on them, pringles are awesome and I'll cut anyone who says otherwise.

the Canadian market is so hosed in terms of quantity and quality of the stuff in the same boxes these days. every time i replace something in the pantry, it's ever so slightly smaller.

It seems everybody wants to keep their product at $3 or $4, and it's turning everything into garbage. lipton green tea is still 24 bags, the tube is still the same size, but you can stick your thumb down between the bags and the container now, and you basically need 2 to get anything beyond yellow water.

Powershift
Nov 23, 2009


InitialDave posted:

Garage has been broken into overnight. Welder and some socket sets stolen.

Luckily it's too messy for them to have had a proper dig in, but still annoying. They've properly trashed the door to get in, too - I have security deadbolts on it, and they've basically just ripped an entire section of door out to make a human-sized hole.

See how cooperative the insurance company feel like being when they open for me to call them.

EDIT: gently caress, they took my mountain bikes too. THAT annoys me.

That sucks, hard.

Hopefully you have the serial number of the welder somewhere, i can't imagine the bikes had one.

sorry to say though, but it often gets worse. you'll be working on something when you realize the tools to do that are loving gone too.

Powershift
Nov 23, 2009


I don't want to spoil it for anyone, but it turns out that logan guy is actually wolverine from the comic books.

Powershift
Nov 23, 2009


Metal Geir Skogul posted:

That loving sucks about the garage. I'd feel violated, and that's a difficult thing to get over.

This weekend I'll have more updates on the Crown Vic. I ordered coils and plugs, and I'll attack the throttle body and MAF as well, to see if it calms down. I'm literally not used to the power. Going from the bus to the Ford...jeeze. Big change.

It does feel like a violation.

My truck was stolen over a year ago, i still haven't bothered putting it back together. I still start it directly with the with the ignition switch mechanism and keep the shifter with me. roof is still stripped, grille is still sitting in pieces. I just can't be hosed. Put money and time into it for the next crackhead to tear up?

It's the same reason i said gently caress it and started driving the lincoln year round. it's just a cheap car. if i don't tear it up, someone's going to back into it or slam it with their door or steal it and tear it up. You can't have nice poo poo.

It's heartbreaking to see people like fknlo or fps_bill and their brand new cars getting hosed up.

cakesmith handyman posted:

Now I want to look up security reviews of my garage doors when I get home.

If you have an electric door with the manual release string hanging down, at the very least remove the handle off the string, if not the string entirely. it takes less than a minute with a coat hanger to poke through the gap at the top of the door and grab that handle.

spog posted:

i am sure that if Dave racks his memory carefully, he'll remember that he had a 3,000 piece Snap-on toolset in that garage as well, it's just that he can't find the receipt for it.

adding up the cost of the missing poo poo can be depressing, even when entirely honest. you don't realize you spend $5000 a year on tools until a year's worth of tools gets stolen.

Powershift fucked around with this message at 13:40 on Mar 10, 2017

Powershift
Nov 23, 2009


cakesmith handyman posted:

I'm bored, recommend me a car film I'm unlikely to have watched before.

The driver

it's from 1978 and includes some of the best car movie scenes ever. The tryout scene with the Mercedes being my favorite.

Powershift
Nov 23, 2009


InitialDave posted:

Clearly it wasn't that educational, then.

I've only watched the (massively depressing) film rather than reading the book, and I was kind of "meh" on the concept.

Within a short time of [poorly defined apocalypse], people with practical skills will be valuable enough to either be in charge of survivor settlements, or very valuable to them. No-one who posts regularly here needs to be worried.

Of course not, we will die glorious on the fury road.

The second society collapses, i'm going shopping for a 6x6 truck to mount the body of my lincoln onto.

Powershift
Nov 23, 2009


Maybe you looked black.

Powershift
Nov 23, 2009


NitroSpazzz posted:

He's posting so I assume he didn't get shot

I said looked black, not are black.

I'm sure once he reached the driver's window he buckled his holster back up.

Powershift
Nov 23, 2009


It's depressing as all gently caress watching cops these days. it's all "we're pulling this guy over because he didn't signal when he changed lanes back there" and then they walk up to the window and go straight into asking where the drugs are."

Powershift
Nov 23, 2009


nm posted:

TBF, every time it is a white dude, he clearly appears to have meth.
As a former criminal defense attorney, cops is my guilty pleasure. Yelling at the screen is cathartic. Also, one place I worked is a common cops location, so I look for people I know.

Yeah, but the difference in treatment even the white druggos and black druggos receive is jarring. And that's when these dickheads have a god drat camera pointed at them.

Powershift
Nov 23, 2009


NitroSpazzz posted:

I know this has been asked and answered 100+ times but this time I'm saving it so I don't have to ask again.

Could someone give me the run down on good/bad diesel truck engines? I've come to the conclusion I'm most likely going to need to buy a truck capable of towing the race car and am fairly clueless. Ford/Chevy/Cummins/etc engines I know nothing about other than some are good and will run forever while some are poo poo and guaranteed to blow up or be a bitch to work on.

For example would this truck with the 7.3L turbo diesel make a good tow vehicle? https://knoxville.craigslist.org/cto/6041192415.html
I'd be towing the race car (~2200lb), tools and spares in an enclosed trailer.

Holy poo poo, buy that loving thing.

All of them are a bitch to work on, and some parts are expensive, but you'll make it up on fuel savings. with the 6.9/7.3/7.3ps, 5.9 12v/24v and pre-emissions duramaxes.

Powershift
Nov 23, 2009


bolind posted:

Maybe check out the powerstrokehelp.com yelling guy? He knows a thing or two about the Ford side.

A few years ago, his 7.3 powerstroke shop truck died at only 798,169 miles

https://www.youtube.com/watch?v=HrdcKBBVTJM

they pulled it apart and replaced only what was broken. it's now at 910,000 miles

https://www.youtube.com/watch?v=dmkQrLLzh3o


The thing i like about diesels(apart from the 6.0, 6.4, and anything with a DPF) is that when you have to fix it, you're not just spending money to get level. Repairing the common failures as they fail gets you 50 and 100hp at a time.

Powershift
Nov 23, 2009


to add to that

ford:

The trucks: coil spring front end trucks ride rough as hell but you don't care because it's a truck and it's supposed to, early twin-i trucks wander and wear tires weird sometimes, coil spring 4x4 trucks get death wobble. the truck around the engine is usually pretty solid. you have to replace ford EOD and 4R100 transmissions every 100,000 miles it's pretty much a maintinence item. 5r110 is much better, but only stuck to bad engines. The ZF 5 and 6 speeds start out mediocre but seem to stay mediocre forever.

6.9/7.3 idi - slow as hell, if they get out of of timing you have to find an old kook with the right tools to deal with it.
7.3 powerstroke - go forever, if it hasn't been done you'll have to do the injector harness under the valve cover, might as well do glowplugs at the same time. ECU controlled and 20 year old ECUs can have 20 year old ECU problems. you need an expensive computer to diagnose major problems.
6.0 - $9,000 bulletproofing required
6.4 - If you can get a truck that had it's emissions equipment properly removed early in life, it should run forever. High miles on stock EGR or any DPF trashes it, if there's no risk of getting caught for pulling that stuff
6.7 uses the Bosch Cp4.2, early 2011s had bad ones, all CP4.2s are suspect.

GM:

Probably the most solid truck if it's not beat on. interiors start out bad, go rapidly downhill. frames are waxed not painted or e-coated, so they rust quickly in rusty places, bodies rust all to poo poo right quick. 4x4 GMs will eat a hole in the transfer case. there won't be used cases around because they all do it. The allison is probably the best transmission, the 5 speed can be turned into a 6, but it's not worth it unless you tow 50k+ a year

6.2 fine but slow
6.5 slow, blocks suspect to cracking in half even at stock power levels
early 6.6 injectors go bad early and often. duramax tax
later 6.6 burns massive amounts of fuel in the DPF. used the cp4.2 from 2011, can explode. huge duramax tax.

dodge:

Not much truck around the engine. front suspension on ball joint trucks require constant attention, a lot of little things gently caress up adding to big headaches.
Dodge never put a "good' transmission in their truck until the most recent ones with the aisin. automatics explode, transfer cases explode, NV 5/6 speeds have weak synchros so they start out amazing and quickly go to poo poo, the G56 6 speed is weak as all hell, and any sort of engine tuning will twist the case and mash the gears.

12v 5.9: slow as hell stock, KDP to deal with
early 24v 5.9: VP44 weakness, a lot of rubber in the fuel system that likes to dry out. idiot magnet so watch for abuse
later 24v 5.9: common rail, if the fuel pressure is bumped up without shimming the fuel rail, injectors can constantly leak fuel into the cylinders washing oil off the cylinder walls causing compression loss, or cause the truck to run rich melting important engine gubbins. also idiot magnet
6.7: easily killed by heat, abuse, DPF. huge idiot magnet.
3.0: uses CP4.2 driven right off the exhaust cam, so when it goes, it takes the engine with it.


You can take any single owner high mileage truck and care for it and it should last a lifetime. A barely out of warranty brotruck owned by a douche will rob you blind. owner is almost as important as mileage.

Powershift
Nov 23, 2009


NitroSpazzz posted:

Same pictures are posted in a few spots all over the country, knew it was way too cheap. I'd like to stay under $5k and may end up going gas since they're cheaper and there's so many more of them available.

It would basically be used for towing but I'd probably drive it into work every other week or so to keep fluids moving and stuff. At this point I'd be aiming for 5-10 track days a year with the closest track around 200 miles away. There's really no reason for me to buy a big truck in reality but it would be useful to have since the girlfriend is probably selling her Tacoma which leaves us with the Courier which probably has a lower tow rating than the VW.

At this point I'll probably just borrow a truck/trailer or rent both from u-haul unless something pops up.

Get you a car that can do both. 70s full size fords are rated to tow 7000lbs.

How baller would you look showing up to the track day with the car on the back of an LTD

Powershift
Nov 23, 2009


NitroSpazzz posted:

One of the guys on our team always used old ambulances, he had a huge flat bed he transferred between them as they died at a million miles or whatever. Multiple times he pulled three cars on a trailer and one on the bed.

Never thought of that, that would be pretty great. Make a ramp truck car out of some old boat of a car.

oh gently caress. rampcar limo.

BRB limo shopping.

Powershift
Nov 23, 2009


NitroSpazzz posted:

I'd love to make an old 7 series BMW into a ramp car even if they are hugely impractical and it would end up costing :homebrew::homebrew::homebrew: If Citroen can do it why couldn't I? other than complete lack of fabrication or anything else



The citroen is FWD, you can make any dumb FWD junk a car hauler pretty easily.



like this guy. this is the guy you would want to be friends with.

gently caress, now look what you've got me looking up. I had poo poo to do today.


Powershift fucked around with this message at 21:24 on Mar 16, 2017

Powershift
Nov 23, 2009


The Door Frame posted:

Yeah, but you're living in Detroit...

I would imagine there are advantages

:911: This is 911 what's your emergency
:kingsley: There's some idiots doing donuts in the middle of woodward
:911: How many shots fired?
:kingsley: shots fired? what? none
:911: Sir, this is an emergency line, prank calls are a felony

Powershift
Nov 23, 2009


Seems like a good opportunity to paint it dukes of hazzard orange with the 01 and flag and everything.

Powershift
Nov 23, 2009


I could see that being useful for a repo guy or something.

Powershift
Nov 23, 2009


Enourmo posted:

Mam I know I'm fat, but apparently "medically normal" weight for someone my 6'5" height is 150 to 200lb? I'm pretty sure I'd look like a stick figure at that weight.

At 6'9, when i first got sick i dropped to 240lbs, and was nothing but skin and bones, but still "overweight' according to BMI.

to break into the "normal" range on BMI, i would have to be dead and be missing a leg. The bottom end of "normal" at 6'9 is 175lbs which is loving hilarious.

I'm about 265 right now, and if i went in and told a doctor i wanted to lose 90lbs, they would send me to a therapist.

Powershift
Nov 23, 2009


Applebees Appetizer posted:

I've been trying to gain weight, loving crohns disease would wither me away if I let it :(

Keep fighting. I've been battling UC, completely off meds, the remicade quit working, and the only alternate suggested by the doctor is surgery.

They're really close to pinpointing the causes, and solutions. in UC and moreso in chron's, there's significantly lower diversity in the gut biome. They can basically tell with almost absolute certainty by looking at the population of bacteria in your colon whether you're healthy, have UC, or chron's. Interestingly, they can tell with around 90% certainly if you're obese just by looking at your gut bacteria, although they're not sure if it's cause or effect. In trials with rats, they could take a clean mouse, and populate it's gut with the fecal bacteria of an obese person and without any other change of environment, the mouse would become obese. They could populate the gut of a clean mouse genetically pre-disposed to colitis with the fecal bacteria of someone with colitis, and it would form in the mouse.

Fecal transplant will likely be the cure, but the FDA is trying to say that for it to be a treatment it has to be produced in the same sterile environment as pharmaceutical biologics, which is impossible. it's only approved right now for treatment of recurring C. Diff infections where anti-biotics have failed. It seems to be a lot more complicated than a single healthy donor to someone with disbiosis, the C. Diff patients they usually use a combination from 7 or 8 healthy donors to increase the chances of a healthy population of microbes growing.

It's interesting what could be connected. Diabetes and obesity through insulin resistance, cholesterol and heart disease through triggers caused by unprocessed bile acids, most auto-immune disease from eczema to arthritis or chron's, and even possibly things like rett's disease, depression, or alzheimers. The next decade of medicine could be entirely "eat poo poo and live", and in 20 years people could be horrified that we used broad spectrum anti-biotics not because of superbugs and the like, but because of the destruction it causes within the gut, which has far more to do with every other part of the body's function than we ever thought.

The big problem is all of the research is academic and non-profit, because you can't patent poop.

it's completely painful to think back at the treatments i've gone through for this, and how they basically did the worst things they could possibly do at every step of the way. If antibiotics cleared it up in a week, why would they then not treat it as an infection? why would they treat what acts like an infection with immune suppresants? Why would they use anti-biotics to clear the gut flora, and then do nothing to healthily re-populate it? Just kill everything and then straight to garbage half cooked hospital food. With science clearly moving quickly towards a solution, why are they still removing people's loving organs forever denying them a chance at a cure?


Applebees Appetizer posted:

I can't complain too much, there are people that have it a lot worse than me. I'm 6 foot, used to average about 165, and went as low as 148 when I was first diagnosed, and now I can keep it around 155. If I eat a poo poo ton and lift weights I can stay around 160 but it's a lot of work. Especially with low energy issues, pain, and just not wanting to eat in general cuz of the disease.

I just saw a medical marijuana doctor recently and I'm waiting on my card so hopefully that will help :)

That's because the traditional treatments, immune suppressants, only treat 1 symptom, which is the immune system attacking the bacteria, and damaging the GI tract in the process. They don't even begin to address other issues caused by disbiosis like the depression that comes from a lack of serotonin production in the gut and potential insulin resistance leading to fatigue. They don't consider those problems as being part of it because they don't yet have an answer for them. They think if you're not on the toilet 20 times a day it's under control, and then going 5 days at a time without sleep is a different doctor's problem.

Powershift
Nov 23, 2009


I tried CBD oil for a while, but again it's only mild symptom management. You have to watch because a lot of "commercial" marijuana strains are high THC and almost no CBD, which is the opposite of what would help. CBD helps with inflammation, and an increase in appetite can help you eat enough to not starve, but again all it's doing is managing a few symptoms. Depending on the symptoms though, it might be all you need to feel normal

All of the biologics like humira, remicade and simponi all have at best 50% efficacy, and that's in the trials they're willing to publish. With long term steroid use, the cure is probably worse than the disease. So many doctors are practicing 30 year old science with this because it's easy and profitable.

My biggest problems with appetite and food seem to be almost entirely in my head. From keeping food journals, writing what i ate and correlating that to symptoms, i ended up identifying basically all food with pain. I would gag and get nauseous at the thought of eating something, but if i force myself to eat, within a few bites it's fine. It's just really hard to force yourself to go through the effort of preparing a meal, and i could imagine marijuana would help with that.

UC is a little different, in only affecting the colon, but what i've had success with is avoiding any food with emulsifiers like sodium stearol-2-lactylate or polysorbate 20/40/60/80, they've been proven to allow bacteria to transverse the mucosal layer in the colon, attempting to repopulate the gut somewhat with kefir yogurt, which is somewhat counterproductive with lactose intolerance but it contains a lot of the same strains as a probiotic called VSL 3 which has been proven to help, but is also pretty expensive. prebiotics like bananas and red wine, a poo poo-ton of fibre when my butthole can handle it, and a ton of berries and fruit.

I'm closer than i've ever been off prednisone and antibiotics, it feels like it's just the last few inches of colon to heal. haven't had blood in a month, i can fart without risk of it not being a fart. Starting to get my brain back, enough to at least attempt to research a way out of this, and get enough control over it to last until FMT is available or i can at least get into a clinical trial for it. A lot of people have tried to do it on their own, but doctors can't help beyond screening your donor for you, and success with a single donor is pretty low.

It's a huge pain in the rear end to research this stuff, because it seems anybody who wants to can call themselves a doctor, and a lot of bullshit "naturopaths" latch on to bits and pieces of the science, and begin to bend it to their agenda. You get 10 paragraphs into Dr. fuckface's dissertation and he starts saying poo poo like "leaky gut" and "detoxify" and you realize his doctorate is in magic from the christian science university of the bahamas and in the time you lost reading his bullshit, you could have gotten that same accreditation.

Powershift
Nov 23, 2009


The Door Frame posted:

Any Chicago locals know about Southside Hacker Space?I remember them coming up in the chat thread a while ago, and some actual metalworking tools and actual experience wouldn't be unwelcome


Spoilers for medical whoopsies
I had a friend in sophomore year with UC that was actually misdiagnosed Diverticular Colitis (DC). I can't blame her doctors, since she didn't want to be known as "that girl with UC" and intentionally missed several appointments with specialists and ignored their advice. She eventually needed a colostomy for ~3 years, a partial bowel resection, and so many -scopy procedures I don't even remember. Eventually, they did reverse the colostomy before her family moved to Virginia and she had to be weaned off of half a decade of opiates. Basically, it can necessitate surgery, but only if you aren't actually working with your doctors to get healthier and let your disease progress improperly treated. Or just without actual treatment, just like diabetes or most chronic conditions

Even with treatment, the end result is often surgery. Some people are lucky, respond to the most basic drugs like mesalamine and carry on with it for years. I went through everything, asacol, azathioprine, 6mp, simponi, remicade. each time one failed with a week or two in the hospital on IV antibiotics and steroids. people who have had the surgery and have the j-pouch surgery which creates a little mini-colon out of the end of your small intestine often still end up getting pouchitis.

For the first year, i was simply diagnosed as "indeterminate colitis" because how it's diagnosed can affect what treatments and drugs are approved, and what drugs insurance companies will cover, and it's difficult to get them to accept a different diagnosis. I had to be diagnosed as ulcerative colitis to get simponi covered by the government drug program, otherwise it would have been $2,100 every 2 weeks. when that didn't work and i went to remicade which hadn't been approved yet for UC, it was covered through the drug company's "compassionate care" program until it was approved by the government for UC. that would have been around $7000 every 6 weeks.

To say surgery is necessary only if you aren't working with your doctors is not only wrong, it's insulting. Still, surgery at this point with solutions on the horizon seems insane, especially with what's known now about the actual functions of the bowel.

Powershift fucked around with this message at 08:01 on Mar 21, 2017

Powershift
Nov 23, 2009


The Door Frame posted:

Oh drat, I didn't mean to be condescending. I'm mostly familiar with Crohn's disease and the one friend with DC who who actively avoided treatment, so maybe my view is a little skewed. From what I've learned from listening to doctors, nurses, and a bit of my own research is that most modern treatments for IBS diseases try to avoid creating stomae if at all possible

I suppose that I thought of "ideal treatment plans" instead taking the next step and thinking of real world treatments. I have firsthand knowledge of how insurance will gently caress around on the most basic level of care if they get the chance, so it should've been the first thing I thought of when "modern treatments" was a part of the discussion. And it could just be American insurance issues, but I've found that doctors are often not willing to prescribe newer drugs, except after trying everything else, because they know that they'll have to fight the insurance company every time those prescriptions try to be filled.
Insurance coverage issues can delay the proper treatment until things become much worse. Which in this case is scarring and diverticulitis, which do require surgery

Chron's disease is a little different, as it affects the entire GI tract, so even if you remove the bowel, it can start in the small intestine. Diverticulitis can happen to anybody, as you get older, diverticules can form. if something gets lodged in there and infected, it can get inflamed, to the point where it has to be surgically removed.

It's not just the US, government drug programs here in canada are like a stick in the mud with newer drugs, largely because of how combative the drug companies are, it's nearly impossible to get actual information on the drugs, even for the doctors prescribing them. http://www.cbc.ca/news/health/drug-safety-health-canada-white-paper-1.4020384

In the US, the drug companies aren't required to publish every study on a a drug, so if they fund trials 10 trials and only 4 are favorable, they only publish those 4. Still, even the best newest drugs like entyvio in cherry picked tests are only around 50% effective, with a placebo being 25% effective. And even then it's almost always temporary, because they're live antibodies which your own body will identify as invasive and form antibodies against. Basically, the drugs that do work often only do so temporarily, most patients are bounced between them, and the most severe ones are thousands of dollars a month. There's a forum called healing well, where if you want to get super depressed, you can go into almost any thread there and read people's signatures detailing the long list of drugs that have failed them, and the long list of drugs they're on that often aren't working. You can see their desperation and panic every time it pops back up to destroy their life.

Food does make a huge difference, but every person's biome is unique, to the point where they can identify you by it, so what works for you might not work for anyone else. It can also take days or weeks to produce a positive or negative effect if you see one, so your bad day might be caused by some mustard you ate a few days ago. There's also the issue of the trash being sold as food, there could be 4 different brands of chicken noodle soup on the shelf, one of them will contain polysorbate 80, which has been proven to induce colitis. It turns every grocery store into a minefield. And again, if your issue isn't the cells in your GI tract being exposed to the bacteria triggering an auto-immune response, then that's not the cause of cure for you. The elimination diet which some doctors suggest where you start with the most basic foods and add until something causes trouble is problematic too, because if you're starving and your intestinal wall is exposed, the bacteria can just eat that causing symptoms.

Food correlation studies often come up barely swinging to either side because everybody's biome is so different, what gets you into remission might harm your chances of staying in remission, and some changes take days, some take weeks, some damage done by diet can't be corrected without taking extra steps. Your gut biome can change drastically in an hour, and strains of bacteria lost are permanently lost. In UC, they've identified a lack of specific bacteria that metabolize butyrate and other short-chain fatty acids that support the function of the colon. In order to fully understand which foods help or hinder, they would basically have to map your biome to determine what it can actually metabolize.

this is interesting to skim through in relation to chron's, just looking at the fecal bacteria, they can tell within 90% certainty whether or not you have chron's. http://gut.bmj.com/content/early/2017/01/31/gutjnl-2016-313235

So the goal beyond that would be to clear out the GI tract with anti-biotics, and repopulate with a combination of fecal mater from a number of healthy donors so your biome more closely reflects theirs. Even in short trials it's shown to be more effective than all of the biologics . It really does seem to be the light at the end of the tunnel, not only for chron's and colitis, but even poo poo like obesity.

It really is important for everybody to be aware of, colitis is almost becoming an epedemic in young people, and while there's an underlying genetric pre-disposition to it, diet seems to be a trigger. make your kids eat vegetables and fish. never introduce them to mcdonalds.

Powershift
Nov 23, 2009


QuarkMartial posted:

I'm turning 31 this year and started 2017 weighing 437. Now I'm down to 417 and I've been lifting weights six days a week. I feel like I'm kicking rear end and going to be entering my prime strength and weight-wise.

While you should definitely exercise a lot so you don't die of a heart attack, most of weight loss is diet. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406229/

Most people believe it's as simple as "calories in - calories out" but it's really, really not. There are so many complex systems in play like insulin resistance, leptin resistance, and the gut microbiome. It seems the only things dieticians can ever agree on is fructose without fiber to slow it's asorbtion = bad. lots of fiber, particularly insoluble fiber = good.

I would imagine at 437lbs you're at least pre-diabetic so not feeling like poo poo when you're not eating a lot of sugar is the first big hurdle.

Keep up with it though. Dropping 100lbs and then having to walk around carrying 100lbs, you begin to wonder how you ever did it.

Powershift
Nov 23, 2009


The Door Frame posted:

Yeah, my mother has Crohn's and I am starting to think that I'm not just extremely lactose intolerant, but that I might have some form of IBS myself, thanks to intense cramping that's not always correlated with eating dairy... I've been on nearly a dozen different antibiotics in the past few years (thanks, VRE and MRSA) and I have no idea what my gut flora looks like anymore. Considering that by sheer number of cells, humans are mostly not human, that's not a good thing. I'm honestly surprised that I haven't developed C.Diff yet, but that's neither here nor there.
I cannot wait to see the day when the microbiome is understood well enough to allow for legitimate medical treatments for people, instead of hucksters pedaling probiotics with no guarantee that there's anything even in their product, thanks to unbelievably relaxed laws on supplements



As an aside, I'm well acquainted with ping-ponging between expensive drugs that you need to even function. I've been on every antidepressant on the market except for one SNRI, a couple tricyclics and any MAOI's. And my doctor said that I'm probably better off on no medicine than an MAOI, given ADHD's notorious reputation(s) for drug seeking behaviours making serotonin syndrome(which I've already gotten twice on SSRI's) a lethal inevitability. Just in 3 generic pill prescriptions 150 total pills, my monthly price without insurance would've been $750, instead of $30. Now with a brand name on my plate and a newer generic, it's $1,800 for 150 pills without insurance, and $40 with it. If I lost insurance, I'd lose my ability to work and live, which is a terrifying prospect

There's a non-profit called american gut where you donate $100, and they send you a kit to send them your poo, and then map out the population of it, show you where are you and where you should be in relation to the rest of the population. There's a good ted talk on it here :siren: everyone should watch this:siren: and maybe mail their poo


CAT INTERCEPTOR posted:

Actually it is - Basic law of thermodynamics cant be beaten. If you dont eat the calories, you WILL lose them. The complex bit is how your body sets it's base metabolism rate and working out how much food to intake to enable weight loss and also what food works best for you - but even then just eating decent food and not sugar loaded crap goes a looooong way in getting the calorie intake right.

There's really no need to overthink it even if the complex systems are difficult to understand. Eat less than what you burn. Eat food that hasnt been heavily processed. Strength training / HIIT steps your metabolism up so it burns more. ANY exercise helps. Oh and drop the soft drinks, drink water. Water is gooooood.

It is on a wide scale, but if you're leptin resistant, any energy in, the body stores as fat and tells the brain you're starving. If you have certain strains of gut bacteria, it can recover another 10-15% of the energy from starches and sugars that would otherwise be excreted undigested. The brain and body can go into starvation mode, even when consuming more calories than you need, even while storing that energy as fat, and while you do burn calories exercising an hour a day, the other 23 hours, the body can deprive muscles and organs of energy because it believes it's starving to death. Excercise doesn't guarantee an increased resting metabolism.

Diet, how it's absorbed, it's make-up, what percentage of the calories are available to you, and how your body decides to use what it takes in is far more important than calorie count. Your brain is a tremendous rear end in a top hat, and overcoming it's fuckups is a lot harder than calorie counting.

Powershift
Nov 23, 2009


QuarkMartial posted:

I dig it. I've been tracking calories and macronutrients (macros bruh! :v:) in myfitnesspal. I figured out I don't much care for sodas, so I quit drinking them sometime last year. I basically drink water, black coffee, and skim milk. I never much snacked on sugary stuff; my issues were over eating because I eat super fast, and if I went for a snack, it was (calorie-wise, most of the time) something that could constitute another meal. Chips and dips, homemade quesadillas, etc.

I enjoy cooking and am in an environment as a teacher where I can finally do proper meal preps. Stopped all the junk food and fast food stuff and went for more whole grains, lots of leafy greens and simply prepped veggies each day, and lots of protein (lots of chicken breasts and thighs, fish, ground turkey, not a lot of red meat). Oh, and a LOT of measuring to keep that portion problem in check. For dinner, my wife and I get HomeChef meals delivered, which are a lot of fun for us. Portioning is easier since it's just half of everything. The only problem is that they tend to be high in salt, which sucks (I am on a water pill which flushes most of the salt out, but still).

tl;dr: Beach body 2018 here I come!


Yesterday went from 49 in the morning to 88-89F in the afternoon. Today, we had tornadoes. Oh, Tennessee..... Seriously, my truck no longer rides like a death machine, I'm ready for nice weather to ride around in!

That's awesome, that's exactly what you have to do because the grocery store is stacked against you. 85% of the poo poo in grocery stores has added sugar, a lot of it for no reason, and they have 20+ names for it so they can stuff more and more of it in. Sodas are a problem, but when you drink a soda, you know you're drinking sugar, you're doing it because it's sweet, but when you grab a loaf of bread or a can of soup you don't think "this is going to be a delicous sweet treat" you read the label and sugar is the 8th ingredient, but there's also molasses and cane juice and maltodextrin and dextrose. most of the "healthy" sugar alternatives are still essentially 50% fructose and 50% glucose, so it doesn't matter if it's organic free range grass fed honey, it's still 50% fructose that the liver won't do gently caress all with except turn to fat.

That's why we're starting to see kids with the livers of 60 year old alcoholics. We're turning them into foie gras.

Powershift
Nov 23, 2009


It's unbelievable how relevant the 2500k still is, but the 4 thread limit is being hit.

Mine has been running at 4.8ghz for nearly 6 years now. My laptop with a 2ghz C2Q is turning 8 years old this year and still rocks all kinds of stuff.

Back in my day, a 3 year old computer was complete trash.

Powershift
Nov 23, 2009


Yu-Gi-Ho! posted:

I never did hit 4.8 - I think the highest reliable speed I ever hit was 4.6. Unfortunately, when I decided to download the UEFI to replace the BIOS for my board, it wouldn't even attempt to boot until it was dropped to 4.1, then I could bump it back up to 4.2. It reboots fine, but if it's off for more than a few minutes it tries to boot a few times before defaulting the settings and giving an OC FAIL message, and I get to do the 4.1, let it POST, then bump to 4.2 bit again.

For my motherboard, there's no going back to BIOS once you're gone to UEFI (the update tool fails - there's a couple of workarounds, but you risk bricking the board... like I can just walk into Micro Center and pick up another Z68 board these days?), and Gigabyte only released one version of UEFI for this board (but they've released plenty of BIOS updates since then). Damnit Gigabyte.

Honestly though... I don't notice a difference between 4.6 and 4.2 in 99% of what I do. Core Temp shows this thing chilling at ~900 MHz most of the time. Aside from the boot hassle, I've had exactly two BSODs on this build... both due to driver issues.

Whenever I do upgrade, the CPU and RAM are going into my mom's system (also Sandy Bridge, but it's an i3). I think it'd be a decent upgrade for her. She'll probably get the 120GB Samsung SSD I have in here too.

I coasted straight up to a hard stable 4.8ghz limit at 1.3v vcore. no multiplier, frequency or voltage would let me past it.

I've since had to bump it to 1.32, but it's still truckin.

Powershift
Nov 23, 2009


That's your god drat president, americans.

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Powershift
Nov 23, 2009


CAT INTERCEPTOR posted:

I'm trying to reconcile that comment and failing

Edit : I've lost 3kgs inthe last two days and now I cant loving fart. gently caress YOU STOMACH

You don't really realize how much good farts matter until they begin to betray you.

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