Blitter posted:

I dunno, do you think it might be wise to not make assumptions given that the mutations present in the 1.617 variants have also produced reduced efficacy in other studies, particularly against less performant vaccines like AZ?

Does that look like doomposting from the CDC? Are they well known for being over cautious?

Obvious this needs further study, but some preliminary results suggesting 1.617.1 is 7-fold more resistant to neutralization by sera suggests a cautious approach as well

The advantage in transmissibility is concerning, just by itself frankly.

But sure, it's just doomposting, whatever.

Blitter posted:

From the article, yes that was fully vaccinated for 0.03%. This includes the effect of any NPI used during the study duration too of course.

The infectivity numbers are interesting compared to this pre-print

Fluffy Bunnies posted:

Okay 30, yeah, sure. Worry about 30.

Did nobody at all buy a treadmill? I bought a treadmill The little peddle bikes that go under your desk are only like $25. Now I'm sad for people. Frick.

Snowglobe of Doom posted:

Here's a fun project: take the CDC's national forecast from July 19 which was projecting that the weekly cases by August 14 would be somewhere between 92,000 (best case scenario) and 803,000 (worst case scenario):

https://twitter.com/CDCgov/status/1418311164472315907

..... and then overlay that with the updated reported averaged case number from July 20 to 27:

Oops, we already blew straight through that 95% prediction interval, their worst case scenario projection was too optimistic.

Snowglobe of Doom posted:

Platystemon posted:

What is the point of the FDA if they can’t look at the data and make a formal determination on the safety and efficacy of the vaccine at this point?

I have been told that the president of the United States cannot even request a timeline for the decision on pædiatric emergency use authorization, because that would involve ~corrosive political pressure~, but come on. Is there any genuine doubt, in the mind of any person, that the FDA will approve this vaccine? I’m sorry, but you can’t watch a hundred and sixty million citizens receive it, turn around, and say “lol whoops. turns out it was swamp water”.

I am under no illusion that the vast majority of the people currently whining about “unapproved experimental vaccine!” won’t immediately move to the next redoubt, but that does not absolve the process of being broken.

How are u posted:

Covid is not going to give anyone Parkinson's or anything like that, jesus christ. Temporary loss of taste and or smell is not a big deal.

Comfy Fleece Sweater posted:

Gaaahhh
Also what percentage of people on ECMO actually make it?

Mr Luxury Yacht posted:

It's actually basically a coin flip. Survival rate estimates range from the low 60s to somewhere in the 40s for COVID-19 patients depending on the study.

But either way something that is definitely worth trying, especially for younger patients. It's a last resort for sure but it's not something like a 95% mortality rate, patients have a pretty decent chance of surviving.

MrQwerty posted:

I worked in pharma for a half-decade and, while everyone at the top is absolutely in it for disgusting, profit-motivated reasons; most everyone else, from discovery to production, generally want to help people in some capacity. The COVID vaccine is not some government control + profit motive wet dream come to life, nobody even gave a gently caress about mRNA vaccines when they were looking into them as an HIV vax and the Federal government is just now beginning to take baby steps like "making people who took anthrax vaccines get vaxxed for COVID," and, "acknowledging that vaccine mandates are a real thing."

As such, when I read poo poo like that, I'm going to treat it as an unfounded conspiracy theory that drat near convinced someone to not get vaxxed, but the social pressure was too great.

I was a teenager/early 20's during Bush 2 as well and have no love or trust for the Federal Government, but seriously.

MrQwerty posted:

CMOs in the US are absolutely making money and generating work filling AZ

Mr Luxury Yacht posted:

It wasn't really needed. By the time they got their poo poo together after their whole clinical trial fuckup (gee who would have thought testing your COVID vaccine on the elderly would be important?) the US was so flooded in mRNA shots it was kind of pointless.

Like it's a good vaccine at all but when you have a basically unlimited supply of Pfizer and Moderna what niche does a vaccine that had, while good protection, still somewhat inferior protection, and that risk of blood clots (while small) the mRNA shots didn't.

Like a big thing with EUAs is the whole benefit to risk calculation and even though the blood clot risk was small, what sense is there to risk it just to get slightly lower protection when you can just use Pfizer/Moderna instead? J&J at least had a niche in being a single shot.

AZ wasn't making any money off it in Canada either but as soon as mRNA shot supplies picked up it was phased out with second AZ shots replaced by mRNA. But back in the winter when we had nothing? Yeah the math was a bit different then and it was being administered.

Songbearer posted:

WHAT DOES THE BRACKET MEAN.

DID A 5G NANOBOT NOT TERMINATE ITS CODE CORRECTLY?

VERY CONCERNING... EYES OPEN PATRIOTS!!!

Snowglobe of Doom posted:

If anyone was wondering how patients would be prioritized during triage here's a list of 'tie breaker' criteria from Idaho
https://twitter.com/audreydutton/status/1438512522106007553

Iron Crowned posted:

I'd like to see the rest of that scene, but instead of the Vulvalini lady, it's a rusty rear end Chilli's sign.

Raskolnikov2089 posted:

Little from column A, little from column B. The pathway COVID uses to infect cells causes the immune overreaction that is thought to be one of the causes of long COVID, but there is mounting evidence COVID is pulling an HIV and hiding in different organs long after your infection period is over.

In the meantime though, every time you get it you're aging your immune system/organs, making it easier to get even sicker the next time you're infected. They're starting to find heart damage in many asymptomatic cases (small sample but: https://jamanetwork.com/journals/jamacardiology/fullarticle/2768916?referringSource=articleShare

Try to avoid catching it until there are some good therapeutics on the market. There's no getting used to COVID.

Comfy Fleece Sweater posted:

https://twitter.com/GillianMcKeith/status/1454444208027324416?s=20

Yeah yeah yeah, my question is : How did Kaiser Permanente hire nurses who don’t believe in medicine ?

Edit: I get schools can’t be expected to hire teachers who believe in science, and police wouldn’t give a gently caress about vaccines, I get that. How does a hospital hire a nurse that doesn’t wear a mask and understand vaccines and pretends to care for others

Elea posted:

Congrats. Did your doctor encourage it if you consulted them? I've heard a lot of stories of doctors giving conflicting advice to pregnant women on the vaccine.

My own doctor said boosters were for very specific people one day before the state said they were for everyone.

Darth TNT posted:

Just how I look at it.
Even if you have a breakthrough infection, generally the virus doesn't do that much any more. As far as I've read the only mom and unborn fetuses who are at risk are those with serious infections. It stands to reason that it wouldn't be that dangerous if you're triple protected.

Beachcomber posted:

That is very upsetting and must be very hard for you.

I don't know why you have two apartments, but if I were you I'd just completely move into the other one for the duration of the pregnancy, but I'm also a bit of an overreactor

Strep Vote posted:

You are so vulnerable when pregnant that I would seriously consider severing from a partner that doesn't take it seriously.

Darth TNT posted:

I'd need to dig up sources. I was certain I either read in the local news or saw it on some local talk show that (barring edge cases like imuno compromised and people above 50) generally the vaccin was good at keeping a serious infection from happening. Not that you're immune, but that you would generally at least not end up in the hospital any more.

I have read the article about the asymptomatic infections as well. However, the versions I read referred mostly to the first wave of Corona and pointed to unvaccinated women. Link in Dutch I'm afraid, but it links through to some UK, Spanish and US research near halfway of the text


That said, please please don't take what I said as me telling you to take it easy on any and all basic counter measures such as social distancing. I'm just trying to not make you more stressed out while still keeping to the rules. I would never take any risk with an unborn child. I remember how paranoid me and my wife were around our own and it wasn't even COVID period back then.

Take the precautions that allow you to feel the most relaxed.

Pinecone Sample posted:

They are very similar. That is also generally unlikely of the way your immune system responds.

It could theoretically happen in one extremely immunocompromised person who is exposed to each at almost the same exact time, and a long incubation in that person is where our deltomicron mutation would arise!

Seth Pecksniff posted:

At this point if you don't get it you're either protected by God or you live alone on a mountain, trap your own food and haven't seen another human for 20 years

Here's hoping for a speedy recovery y'all!

A Strange Aeon posted:

If we didn't have a 4 year old, my wife's and my anxiety would be tremendously less, but the reality is I don't see how much we can do about the risks. We already don't go anywhere we don't have to, always wear masks, etc.

But keeping our daughter out of preschool for some indeterminate amount of time just in case wreaks havoc on our whole family.

Parents are really forced to engage with this in a way adults who live by themselves and can work from home aren't. It sucks a lot.

Cretin90 posted:

What are you all doing to get exercise right now? My apartment gym is packed. My local gym is packed. By the time I get off work it’s dark and 18 degrees F outside. I’m in a 3rd story apartment so treadmill is out of the question. Im considering picking up an exercise bike and occasionally dragging my fiancé out for pitch dark 20 degree runs. Gym could be ok with n95 but it’s just full of heavy breathing New Years resolution people and makes my skin crawl.

E: Mostly asking about cardiovascular but the weights-oriented responses are helpful too.

Platystemon posted:

False positives are quite unlikely. The published rate is two percent. They may truly be below that.

There’s also this anecdote:

Yes, Cue is a nucleic acid amplification test, but I would not treat it as a false PCR.

Oracle posted:

False negatives are a lot more likely than false positives. Get a PCR test.