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Pillowpants posted:Same but every movie ever Someone has never seen No County for Old Men 
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Aug 11, 2021 20:12
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| # ? May 14, 2024 04:11 |
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triple sulk posted:serious question for all the respirator people, are you all just so immunocompromised that if you get covid you're like 100% sure you're gonna die and/or you have to be around people 75% of the day or what (1) my father is recovering from radiation treatment for cancer in his neck (2) my mother had a severe aneurysm and experimental brain surgery a few years back (3) my SO works full-time in a major metropolitan hospital, and was on a Covid-positive unit for several months in 2020 (4) my sister and her SO were infected by colleagues who got tested after being warned via contact tracing, but went into work for the day between test and positive result (5) I've had multiple stays in the Infectious Diseases ward of a different major metropolitan hospital because my immune system isn't necessarily compromised but it is definitely "non-standard". gently caress it, let's provide visuals. In 2019 I had a mild ingrown nail on my fourth finger. Bacteria got in, swelling occurred. Despite being prescribed oral antibiotics, then IV antibiotics, then IV antivirals, and finally a combo of the above, it progressed for 9 days as seen below. NSFW, it isn't godawful (i.e. no blood or open wound) but also depends on how you react to pus and stuff. Individual spoiler tags so you can bail if you regret checking it out.      This was the mild incident. The 2017 infection in my foot was much less pleasant. All of that is why I'm part of respirator crew. And it felt good to type that all out because goddamnit people up here are way too complacent and nonchalant about Delta. There is no downside to a respirator and it comes out cheaper than disposable filtered masks in the long-term.
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Aug 11, 2021 20:12
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https://www.youtube.com/watch?v=lYcp1bUb4lU
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Aug 11, 2021 20:13
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don't ever post anything like that again or else bro
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Aug 11, 2021 20:13
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you already have 1 strike for the falcon guy side quest and this is strike 2 for nasty toe
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Aug 11, 2021 20:14
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Marzzle posted:sure bud whatever you want to believe we're sorry for not taking anti-White racism seriously
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Aug 11, 2021 20:15
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SchrodingersCat posted:You can generate antibodies against more than one part of a virus, so as long as some of your antibodies can slow the virus down your body can adapt to the newly presented antigens and clear them out. Yeah, I agree with this. However I'm trying to draw attention to specifc research that suggests that COVID might not in fact be able to render the vaccines induced antibodies and the associated B-Cells totally useless. Note once again this might be a bogus, naive interpretation of the presented content, and this is just one specific lab study. I'm in part trying to understand how off-base that is. But if true it in a way makes it even worse. Due to our collective incompetence we took what might have been a disease that could be handled well by existing vaccines in concert with NPIs and turned it into a maximally dragged out ongoing crisis, with an associated maximal body count. We might be getting pushed around by a relatively trivial to handle virus, in the grand scheme of terrible viruses observed in nature.
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Aug 11, 2021 20:16
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Just got back from getting a test; one of my roommates started having upper respiratory / sinus infection symptoms, and now two more of us are, as well. All of us are double-Moderna vaxxed and I don't believe any of us have had a fever at any point. Saw a minivan with a couple of kids at the drive-thru site. gently caress. 
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Aug 11, 2021 20:17
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mod sassinator posted:ah yeah it's probably closer to 42% effective after a few months. israel data has a very clear month by month drop from mid 80s 1 month after 2nd dose down to 16% (yes, really) 6+ months after the 2nd dose i think there's something funky going on in both case with the denominators. esp when you consider the british 95% immunity numbers. so nate might be right against his best efforts. i also suspect that the antibodies do wane and that is harmful w/ delta bc it replicates faster than the vaccine mediated immune response
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Aug 11, 2021 20:17
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What's with the COVID thread and fingers We had that guy last year who ripped off his thumb skin while weightlifting and refused to go see the doctor
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Aug 11, 2021 20:18
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tiberion02 posted:So - I work in a 10 person, 100% libs office that was WFH from March 20 to June 1 2021... everyone came back, not a single mask to be found anywhere. they all post here
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Aug 11, 2021 20:19
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Well, I popped positive for Covid today. Was vaccinated back in February. I most definitely caught it from my buddy's wife who also tested positive recently - they're the only people we see and likewise for them with regard to us. We all work from home and do contactless pickup for everything we need, except my buddy's wife recently went into the grocery store for some stuff they missed from their last order and probably got it there (Texas lol). So far I'm only experiencing mild symptoms, but it's still pretty unnerving and does nothing to assuage my doomerism. A group of 4 and half of us were breakthrough cases lol.
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Aug 11, 2021 20:19
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Fun fact: Besides the initial outbreak at the start of the pandemic, the worst day for COVID deaths in King County was Christmas day. But I'm sure we can beat that if we try hard enough.
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Aug 11, 2021 20:20
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Pulvis Sumus posted:Well, I popped positive for Covid today. Was vaccinated back in February. I most definitely caught it from my buddy's wife who also tested positive recently - they're the only people we see and likewise for them with regard to us. We all work from home and do contactless pickup for everything we need, except my buddy's wife recently went into the grocery store for some stuff they missed from their last order and probably got it there (Texas lol). So far I'm only experiencing mild symptoms, but it's still pretty unnerving and does nothing to assuage my doomerism. A group of 4 and half of us were breakthrough cases lol. Sorry buddy, hope you feel better soon.
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Aug 11, 2021 20:20
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Nocturtle posted:
It's not a trivial virus, we are getting pushed around by a virus badass enough to kill people in spite of everything modern medicine can throw at it, and still manages to infect and kill people with acquired immunity. COVID isn't the worst virus we've encountered, but it's decently lethal and if COVID had arisen a century ago you'd probably be looking at a Black Death or at least a Spanish Flu level situation. The only really effective mitigation strategy for COVID is basically cutting off all human contact until we had a vaccine, and then forcibly administering vaccines to stamp it out before novel variants could pop up. It was never going to happen in our society. SchrodingersCat has issued a correction as of 20:24 on Aug 11, 2021 |
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Aug 11, 2021 20:21
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Pulvis Sumus posted:Well, I popped positive for Covid today. Was vaccinated back in February. I most definitely caught it from my buddy's wife who also tested positive recently - they're the only people we see and likewise for them with regard to us. We all work from home and do contactless pickup for everything we need, except my buddy's wife recently went into the grocery store for some stuff they missed from their last order and probably got it there (Texas lol). So far I'm only experiencing mild symptoms, but it's still pretty unnerving and does nothing to assuage my doomerism. A group of 4 and half of us were breakthrough cases lol. Owned. Good luck on a quick recovery.
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Aug 11, 2021 20:21
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My roommate has respiratory problems, and nearly died from a severe asthma attack last year. That's why I'm respirator crew
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Aug 11, 2021 20:21
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SKULL.GIF posted:What's with the COVID thread and fingers Don't worry, he made sure that he was diligent about his respirator.
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Aug 11, 2021 20:22
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Pulvis Sumus posted:Well, I popped positive for Covid today. Was vaccinated back in February. I most definitely caught it from my buddy's wife who also tested positive recently - they're the only people we see and likewise for them with regard to us. We all work from home and do contactless pickup for everything we need, except my buddy's wife recently went into the grocery store for some stuff they missed from their last order and probably got it there (Texas lol). So far I'm only experiencing mild symptoms, but it's still pretty unnerving and does nothing to assuage my doomerism. A group of 4 and half of us were breakthrough cases lol. what version of the vaccines did y’all have?
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Aug 11, 2021 20:23
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Google Butt posted:Sorry buddy, hope you feel better soon. Thoguh posted:Owned. Thanks, hoping it will be speedy as well. Mr. Nice! posted:what version of the vaccines did y’all have? The half of us that got sick both got Pfizer. The ones that didn't get sick both had Moderna.
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Aug 11, 2021 20:25
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Pulvis Sumus posted:Thanks, hoping it will be speedy as well.  I have Pfizer
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Aug 11, 2021 20:27
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Moderna gang rise up
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Aug 11, 2021 20:29
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Iron Crowned posted:
RIP.
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Aug 11, 2021 20:29
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Pulvis Sumus posted:Thanks, hoping it will be speedy as well. oof. i hope you all recover without lasting complications.
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Aug 11, 2021 20:29
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Jon Irenicus posted:Moderna gang rise up
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Aug 11, 2021 20:29
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Pulvis Sumus posted:Thanks, hoping it will be speedy as well. BahahahahahahahHh
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Aug 11, 2021 20:30
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Nocturtle posted:Hey by all means help me understand what's wrong with what I wrote, well aware I'm dumb as hell. I'm trying to understand the implications of this Bieniasz lecture about COVID antibody-influenced selection. If you're saying that I've fundamentally misunderstood the presented content then that's plausible. I don't think you're "wrong" just maybe over-optimistic. Like, what the Bieniasz work shows is that -Spike, by accumulating no more than 20 point substitution mutations, can evade most vaccinated or convalescent people's antibodies completely -If those antibodies undergo a lot of affinity maturation, this seems to be no longer the case -That degree of maturation, in order to be relevant, may require boosters or new vaccines -Absent this smorgasbord of substitution mutations, it doesn't look like there are a lot of other single point spike mutations in the virus's bag of tricks to further escape antibodies Even if you just end things there, I don't think the situation is necessarily "good". If delta achieves a significant degree of antibody escape, while retaining any semblance of it's current R0, then the next 6-12+ months are going to loving SUUUUUUUUUUUCK, worse than anything we've experienced yet. And while the news about affinity maturation is welcome, really exploiting that may require a sustained and very successful vaccination effort--possibly with a new vaccine--and, well, we see how well that's going. There are other concerns, though. One, that, Notorious R.I.M. points out, is that there are proteins other than spike which could play a role in immune escape and these aren't nearly as well studied. The biggest one I have, is that I don't think anyone really knows how much room there is for the virus to become more infectious or more virulent. What's concerning is that, with both the initial emergence of delta and the (still very limited) genomic surveilance we've seen this summer, it doesn't look like pure antibody escape is the primary thing being selected for. With alpha, beta, and gamma variants there was sort of a gradual accumulation of the various big dick immune escape substitutions, but with delta, it doesn't have most of them. Instead, it did some other weird poo poo, particularly it seems at the S1/S2 cleavage site, and just became way, way more effective at causing infections in people. I don't think we have the knowledge to constrain, let alone rule out, further developments in that direction. It may be that instead of defeating antibodies, the virus evolves towards a brute force approach (like delta), and in that case, I don't think we know how well people's immune systems or vaccines will hold up. At the end of the day, though, whatever mutations occur, as long as the spike can be neutralized by antibodies, some vaccine based approach should eventually be broadly successful, and it looks like the virus probably can't escape neutralizing antibodies on spike forever. Anyway this bitch is gonna churn through the entire globe three times over before any reasonable fraction of people are vaccinated with anything, so the best any of us can to is get whatever vaccine/boosters we can to give ourselves the best chance, and limit exposure as much as possible after that. How/when/if this finally "ends" is just speculation. In conclusion https://www.youtube.com/watch?v=UbG3qOWjoKo
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Aug 11, 2021 20:30
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Mr Hootington posted:We are past the peak! Bullshit, there is no way we’re past the peak.
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Aug 11, 2021 20:31
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Getting the impression the official vax breakthrough numbers are bunk
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Aug 11, 2021 20:33
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Pfizer/moderna gang represent we don't know wtf
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Aug 11, 2021 20:33
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I want to make a covid video now, what are some other good song suggestions? Going to do it as a timeline, with the death toll constantly ticking away at the bottom.
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Aug 11, 2021 20:33
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skewetoo posted:Getting the impression the official vax breakthrough numbers are bunk https://twitter.com/SaltySalish/status/1425303390511243270?s=20
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Aug 11, 2021 20:34
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I just want to point out that this poster was probated for 2 weeks for saying "lol @ d&d " in a thread that was gassed lmfao
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Aug 11, 2021 20:35
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lol, hotez sharing some fan mail https://twitter.com/PeterHotez/status/1425536632191692805
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Aug 11, 2021 20:36
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skewetoo posted:Getting the impression the official vax breakthrough numbers are bunk gonna lmao when it turns out like 25% efficacy against infection with delta and the reason nobody showed that is because they weren't monitoring breakthroughs or were using data from prior strains
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Aug 11, 2021 20:36
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Mr. Nice! posted:oh yeah i’m not going out or doing anything. i’m basically sitting at home all day or at my girlfriend’s apartment. just to be clear here, the study in question shows 42% with a 95% confidence interval of 13-62% (meaning there's a 95% chance the actual at large efficiency is anywhere between 13% and 62%, and a 5% chance it's not even in those bounds) also for additional information, the company nference that produced the study is not primarily a research lab, it's a tech company that hires researchers at higher salaries than normal research labs to churn out papers as a side gig to their main gig which is supposed to be pointing ai and big data at existing research papers to draw novel conclusions. they're basically the theranos of research papers
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Aug 11, 2021 20:36
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weren't they already not doing that, how is this a change
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Aug 11, 2021 20:37
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Looks at dd thread Don't know whoever is responsible for the fuckup(everyone) matters in our current worst case situation but hey whatever makes them feel better
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Aug 11, 2021 20:37
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weren't they only tracking breakthrough hospitalizations in the first place? welp too many vaccinated people are ending up in the hospital so we're going go stop paying attention also get vaccinated
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Aug 11, 2021 20:37
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must be a lot of breakthrough cases if you cant keep up
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Aug 11, 2021 20:38
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